DE68906647D1 - Hydroxy-1,2,3,4-tetrahydroaminoacridine, verfahren fuer ihre herstellung und ihre verwendung als arzneimittel. - Google Patents
Hydroxy-1,2,3,4-tetrahydroaminoacridine, verfahren fuer ihre herstellung und ihre verwendung als arzneimittel.Info
- Publication number
- DE68906647D1 DE68906647D1 DE8989121037T DE68906647T DE68906647D1 DE 68906647 D1 DE68906647 D1 DE 68906647D1 DE 8989121037 T DE8989121037 T DE 8989121037T DE 68906647 T DE68906647 T DE 68906647T DE 68906647 D1 DE68906647 D1 DE 68906647D1
- Authority
- DE
- Germany
- Prior art keywords
- hydroxy
- loweralkyl
- hydrogen
- tetrahydroaminoacridine
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
- C07D219/12—Amino-alkylamino radicals attached in position 9
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27178888A | 1988-11-16 | 1988-11-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68906647D1 true DE68906647D1 (de) | 1993-06-24 |
DE68906647T2 DE68906647T2 (de) | 1993-10-07 |
Family
ID=23037088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE89121037T Expired - Fee Related DE68906647T2 (de) | 1988-11-16 | 1989-11-14 | Hydroxy-1,2,3,4-tetrahydroaminoacridine, Verfahren für ihre Herstellung und ihre Verwendung als Arzneimittel. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0369388B1 (de) |
KR (1) | KR0156241B1 (de) |
AT (1) | ATE89553T1 (de) |
CA (1) | CA2003023C (de) |
DE (1) | DE68906647T2 (de) |
DK (1) | DK168290B1 (de) |
ES (1) | ES2054987T3 (de) |
FI (1) | FI90417C (de) |
HU (2) | HU208674B (de) |
IE (1) | IE63038B1 (de) |
IL (1) | IL92307A0 (de) |
NO (1) | NO894547L (de) |
NZ (1) | NZ231376A (de) |
PT (1) | PT92319B (de) |
ZA (1) | ZA898720B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200462B (de) * | 1990-09-27 | 1993-02-21 | Hoechst Roussel Pharma | |
GB2264707A (en) * | 1991-06-18 | 1993-09-08 | Roger Michael Marchbanks | Acridine derivatives for treating alzheimer's disease |
US5422350A (en) * | 1992-09-10 | 1995-06-06 | Warner-Lambert Company | Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use |
US5466696A (en) * | 1992-09-10 | 1995-11-14 | Warner Lambert Company | Tacrine and cytochrome P450 oxidase inhibitors and methods of use |
WO2019207604A1 (en) * | 2018-04-25 | 2019-10-31 | Rajiv Gandhi Centre For Biotechnology | Tacrine derivatives targeting nmda receptor, acetylcholine esterase, butyryl choline and beta secretase activity |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0179383B1 (de) * | 1984-10-25 | 1991-05-29 | Hoechst-Roussel Pharmaceuticals Incorporated | 9-Amino-1,2,3,4-tetrahydroacridin-1-ol und verwandte Verbindungen, Verfahren zu ihrer Herstellung und Verwendung als Arzneimittel |
NZ223875A (en) * | 1987-03-17 | 1991-01-29 | Hoechst Roussel Pharma | 9-aminotetrahydroacridines and related homologues and pharmaceutical compositions |
-
1989
- 1989-11-14 AT AT89121037T patent/ATE89553T1/de not_active IP Right Cessation
- 1989-11-14 IL IL92307A patent/IL92307A0/xx unknown
- 1989-11-14 FI FI895416A patent/FI90417C/fi not_active IP Right Cessation
- 1989-11-14 NZ NZ231376A patent/NZ231376A/en unknown
- 1989-11-14 DE DE89121037T patent/DE68906647T2/de not_active Expired - Fee Related
- 1989-11-14 ES ES89121037T patent/ES2054987T3/es not_active Expired - Lifetime
- 1989-11-14 EP EP89121037A patent/EP0369388B1/de not_active Expired - Lifetime
- 1989-11-14 KR KR1019890016456A patent/KR0156241B1/ko not_active IP Right Cessation
- 1989-11-15 IE IE365989A patent/IE63038B1/en not_active IP Right Cessation
- 1989-11-15 ZA ZA898720A patent/ZA898720B/xx unknown
- 1989-11-15 CA CA002003023A patent/CA2003023C/en not_active Expired - Fee Related
- 1989-11-15 DK DK571989A patent/DK168290B1/da not_active IP Right Cessation
- 1989-11-15 NO NO89894547A patent/NO894547L/no unknown
- 1989-11-15 PT PT92319A patent/PT92319B/pt active IP Right Grant
- 1989-11-16 HU HU593189A patent/HU208674B/hu unknown
-
1995
- 1995-06-22 HU HU95P/P00336P patent/HU211701A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
HU895931D0 (en) | 1990-02-28 |
ES2054987T3 (es) | 1994-08-16 |
IL92307A0 (en) | 1990-07-26 |
NO894547L (no) | 1990-05-18 |
KR0156241B1 (ko) | 1998-11-16 |
ATE89553T1 (de) | 1993-06-15 |
NO894547D0 (no) | 1989-11-15 |
FI90417C (fi) | 1994-02-10 |
KR900007809A (ko) | 1990-06-02 |
DK571989A (da) | 1990-05-17 |
PT92319B (pt) | 1995-08-09 |
NZ231376A (en) | 1992-05-26 |
DK168290B1 (da) | 1994-03-07 |
HUT53087A (en) | 1990-09-28 |
FI895416A0 (fi) | 1989-11-14 |
EP0369388A1 (de) | 1990-05-23 |
FI90417B (fi) | 1993-10-29 |
PT92319A (pt) | 1990-05-31 |
ZA898720B (en) | 1990-08-29 |
IE63038B1 (en) | 1995-03-22 |
IE893659L (en) | 1990-05-16 |
HU211701A9 (en) | 1995-12-28 |
DE68906647T2 (de) | 1993-10-07 |
EP0369388B1 (de) | 1993-05-19 |
CA2003023A1 (en) | 1990-05-16 |
CA2003023C (en) | 2001-05-29 |
HU208674B (en) | 1993-12-28 |
DK571989D0 (da) | 1989-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |