PT92319A - Processo para a preparacao de hidroxi-1,2,3,4-tetrahidroaminoacridinas e de composicoes farmaceuticas que as contem - Google Patents

Processo para a preparacao de hidroxi-1,2,3,4-tetrahidroaminoacridinas e de composicoes farmaceuticas que as contem

Info

Publication number
PT92319A
PT92319A PT92319A PT9231989A PT92319A PT 92319 A PT92319 A PT 92319A PT 92319 A PT92319 A PT 92319A PT 9231989 A PT9231989 A PT 9231989A PT 92319 A PT92319 A PT 92319A
Authority
PT
Portugal
Prior art keywords
hydroxy
preparation
loweralkyl
hydrogen
tetrahydroaminoacridines
Prior art date
Application number
PT92319A
Other languages
English (en)
Other versions
PT92319B (pt
Inventor
Gregory Michael Shutske
John Dick Tomer
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of PT92319A publication Critical patent/PT92319A/pt
Publication of PT92319B publication Critical patent/PT92319B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9
    • C07D219/12—Amino-alkylamino radicals attached in position 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
PT92319A 1988-11-16 1989-11-15 Processo para a preparacao de hidroxi-1,2,3,4-tetrahidroaminoacridinas e de composicoes farmaceuticas que as contem PT92319B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27178888A 1988-11-16 1988-11-16

Publications (2)

Publication Number Publication Date
PT92319A true PT92319A (pt) 1990-05-31
PT92319B PT92319B (pt) 1995-08-09

Family

ID=23037088

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92319A PT92319B (pt) 1988-11-16 1989-11-15 Processo para a preparacao de hidroxi-1,2,3,4-tetrahidroaminoacridinas e de composicoes farmaceuticas que as contem

Country Status (15)

Country Link
EP (1) EP0369388B1 (pt)
KR (1) KR0156241B1 (pt)
AT (1) ATE89553T1 (pt)
CA (1) CA2003023C (pt)
DE (1) DE68906647T2 (pt)
DK (1) DK168290B1 (pt)
ES (1) ES2054987T3 (pt)
FI (1) FI90417C (pt)
HU (2) HU208674B (pt)
IE (1) IE63038B1 (pt)
IL (1) IL92307A0 (pt)
NO (1) NO894547L (pt)
NZ (1) NZ231376A (pt)
PT (1) PT92319B (pt)
ZA (1) ZA898720B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200462B (pt) * 1990-09-27 1993-02-21 Hoechst Roussel Pharma
GB2264707A (en) * 1991-06-18 1993-09-08 Roger Michael Marchbanks Acridine derivatives for treating alzheimer's disease
US5422350A (en) * 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
US5466696A (en) * 1992-09-10 1995-11-14 Warner Lambert Company Tacrine and cytochrome P450 oxidase inhibitors and methods of use
WO2019207604A1 (en) * 2018-04-25 2019-10-31 Rajiv Gandhi Centre For Biotechnology Tacrine derivatives targeting nmda receptor, acetylcholine esterase, butyryl choline and beta secretase activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582995D1 (de) * 1984-10-25 1991-07-04 Hoechst Roussel Pharma 9-amino-1,2,3,4-tetrahydroacridin-1-ol und verwandte verbindungen, verfahren zu ihrer herstellung und verwendung als arzneimittel.
NZ223875A (en) * 1987-03-17 1991-01-29 Hoechst Roussel Pharma 9-aminotetrahydroacridines and related homologues and pharmaceutical compositions

Also Published As

Publication number Publication date
ATE89553T1 (de) 1993-06-15
IE63038B1 (en) 1995-03-22
PT92319B (pt) 1995-08-09
HU208674B (en) 1993-12-28
EP0369388A1 (en) 1990-05-23
NO894547D0 (no) 1989-11-15
HU895931D0 (en) 1990-02-28
FI90417B (fi) 1993-10-29
IL92307A0 (en) 1990-07-26
ZA898720B (en) 1990-08-29
NO894547L (no) 1990-05-18
EP0369388B1 (en) 1993-05-19
CA2003023A1 (en) 1990-05-16
KR0156241B1 (ko) 1998-11-16
KR900007809A (ko) 1990-06-02
NZ231376A (en) 1992-05-26
HUT53087A (en) 1990-09-28
FI90417C (fi) 1994-02-10
DE68906647D1 (de) 1993-06-24
CA2003023C (en) 2001-05-29
HU211701A9 (en) 1995-12-28
DK571989D0 (da) 1989-11-15
DK571989A (da) 1990-05-17
FI895416A0 (fi) 1989-11-14
DE68906647T2 (de) 1993-10-07
DK168290B1 (da) 1994-03-07
ES2054987T3 (es) 1994-08-16
IE893659L (en) 1990-05-16

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19950403