DE68902386D1 - N-pyridinyl-9h-carbazol-9-amine, verfahren zu ihrer herstellung und ihre verwendung als medikamente. - Google Patents
N-pyridinyl-9h-carbazol-9-amine, verfahren zu ihrer herstellung und ihre verwendung als medikamente.Info
- Publication number
- DE68902386D1 DE68902386D1 DE8989123612T DE68902386T DE68902386D1 DE 68902386 D1 DE68902386 D1 DE 68902386D1 DE 8989123612 T DE8989123612 T DE 8989123612T DE 68902386 T DE68902386 T DE 68902386T DE 68902386 D1 DE68902386 D1 DE 68902386D1
- Authority
- DE
- Germany
- Prior art keywords
- loweralkyl
- hydrogen
- halogen
- medicaments
- carbazol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/289,887 US4868190A (en) | 1988-12-27 | 1988-12-27 | N-pyridinyl-9H-carbazol-9-amines |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68902386D1 true DE68902386D1 (de) | 1992-09-10 |
DE68902386T2 DE68902386T2 (de) | 1993-02-11 |
Family
ID=23113557
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8989123612T Expired - Fee Related DE68902386T2 (de) | 1988-12-27 | 1989-12-21 | N-pyridinyl-9h-carbazol-9-amine, verfahren zu ihrer herstellung und ihre verwendung als medikamente. |
Country Status (19)
Country | Link |
---|---|
US (1) | US4868190A (de) |
EP (1) | EP0376155B1 (de) |
JP (1) | JPH0725749B2 (de) |
KR (1) | KR900009596A (de) |
AT (1) | ATE79118T1 (de) |
AU (1) | AU623205B2 (de) |
CA (1) | CA2006529C (de) |
DE (1) | DE68902386T2 (de) |
DK (1) | DK662189A (de) |
ES (1) | ES2044043T3 (de) |
FI (1) | FI896243A0 (de) |
GR (1) | GR3006140T3 (de) |
IE (1) | IE894175L (de) |
IL (1) | IL92867A0 (de) |
NO (1) | NO895222L (de) |
NZ (1) | NZ231943A (de) |
PH (1) | PH27122A (de) |
PT (1) | PT92696A (de) |
ZA (1) | ZA899904B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916135A (en) * | 1989-05-08 | 1990-04-10 | Hoechst Roussel Pharmaceuticals Inc. | N-heteroaryl-4-quinolinamines |
US4994472A (en) * | 1989-08-02 | 1991-02-19 | Hoechst-Roussel Pharmaceuticals Incorporated | 1-(pyridinylamino)-2-pyrrolidinones as pain relievers |
US5179099A (en) * | 1989-08-02 | 1993-01-12 | Hoechst-Roussel Pharmaceuticals Incorporated | 2,3-dihydro-1-(pyridinylamino)-indoles |
DE69016531T2 (de) * | 1989-08-02 | 1995-07-06 | Hoechst Roussel Pharma | 2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel. |
US4983608A (en) * | 1989-09-05 | 1991-01-08 | Hoechst-Roussell Pharmaceuticals, Inc. | N-substituted-4-pyrimidinamines and pyrimidinediamines |
ES2174081T3 (es) * | 1995-07-27 | 2002-11-01 | Aventis Pharma Inc | Uso de n-(pirrol-1-il)piridinaminas sustituidas y no sustituidas como agentes anticonvulsivos. |
US5776955A (en) * | 1995-07-27 | 1998-07-07 | Hoechst Marion Roussel, Inc. | Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents |
ZA989365B (en) * | 1997-10-15 | 1999-04-15 | Boehringer Mannheim Pharm Corp | Preparation for treating alzheimer's disease |
WO2002007822A2 (en) * | 2000-07-21 | 2002-01-31 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR7181M (de) * | 1966-11-16 | 1969-08-11 | ||
EP0073849A1 (de) * | 1981-09-03 | 1983-03-16 | Schering Corporation | Phenyl-1,2,3,4-tetrahydrocarbazole, ihre Herstellung und pharmazeutische Zubereitungen, die sie enthalten |
US4752610A (en) * | 1985-12-04 | 1988-06-21 | Hoechst-Roussel Pharmaceuticals Inc. | N-(pyrrol-1-yl)pyridinamines having memory enhancing properties |
US4792562A (en) * | 1985-12-04 | 1988-12-20 | Hoechst-Roussel Pharmaceuticals, Inc. | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity |
DE3852335T2 (de) * | 1987-04-24 | 1995-05-11 | Hoechst Roussel Pharma | N-(Pyridinyl)-1H-indol-1-amine, Verfahren zu deren Herstellung und ihre Verwendung als Arzneimittel. |
US4806554A (en) * | 1988-01-11 | 1989-02-21 | Hoechst-Roussel Pharmaceuticals, Inc. | Pyrazol and indazolpyridinamines |
US4916135A (en) * | 1989-05-08 | 1990-04-10 | Hoechst Roussel Pharmaceuticals Inc. | N-heteroaryl-4-quinolinamines |
US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
DE69016531T2 (de) * | 1989-08-02 | 1995-07-06 | Hoechst Roussel Pharma | 2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel. |
-
1988
- 1988-12-27 US US07/289,887 patent/US4868190A/en not_active Expired - Lifetime
-
1989
- 1989-12-21 AT AT89123612T patent/ATE79118T1/de not_active IP Right Cessation
- 1989-12-21 EP EP89123612A patent/EP0376155B1/de not_active Expired - Lifetime
- 1989-12-21 ES ES89123612T patent/ES2044043T3/es not_active Expired - Lifetime
- 1989-12-21 IE IE894175A patent/IE894175L/xx unknown
- 1989-12-21 NZ NZ231943A patent/NZ231943A/en unknown
- 1989-12-21 DE DE8989123612T patent/DE68902386T2/de not_active Expired - Fee Related
- 1989-12-22 FI FI896243A patent/FI896243A0/fi not_active Application Discontinuation
- 1989-12-22 AU AU47203/89A patent/AU623205B2/en not_active Ceased
- 1989-12-22 DK DK662189A patent/DK662189A/da not_active Application Discontinuation
- 1989-12-22 PT PT92696A patent/PT92696A/pt unknown
- 1989-12-22 NO NO89895222A patent/NO895222L/no unknown
- 1989-12-22 CA CA002006529A patent/CA2006529C/en not_active Expired - Fee Related
- 1989-12-25 IL IL92867A patent/IL92867A0/xx unknown
- 1989-12-26 PH PH39801A patent/PH27122A/en unknown
- 1989-12-26 JP JP1335256A patent/JPH0725749B2/ja not_active Expired - Fee Related
- 1989-12-26 KR KR1019890019472A patent/KR900009596A/ko not_active Application Discontinuation
- 1989-12-27 ZA ZA899904A patent/ZA899904B/xx unknown
-
1992
- 1992-11-04 GR GR920402184T patent/GR3006140T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NZ231943A (en) | 1992-06-25 |
NO895222L (no) | 1990-06-28 |
US4868190A (en) | 1989-09-19 |
PH27122A (en) | 1993-03-16 |
PT92696A (pt) | 1990-06-29 |
IL92867A0 (en) | 1990-09-17 |
ZA899904B (en) | 1991-02-27 |
EP0376155B1 (de) | 1992-08-05 |
DE68902386T2 (de) | 1993-02-11 |
EP0376155A1 (de) | 1990-07-04 |
KR900009596A (ko) | 1990-07-05 |
ES2044043T3 (es) | 1994-01-01 |
DK662189D0 (da) | 1989-12-22 |
GR3006140T3 (de) | 1993-06-21 |
IE894175L (en) | 1990-06-27 |
ATE79118T1 (de) | 1992-08-15 |
CA2006529C (en) | 1999-08-10 |
NO895222D0 (no) | 1989-12-22 |
CA2006529A1 (en) | 1990-06-27 |
FI896243A0 (fi) | 1989-12-22 |
JPH02247173A (ja) | 1990-10-02 |
AU4720389A (en) | 1990-07-05 |
DK662189A (da) | 1990-06-28 |
AU623205B2 (en) | 1992-05-07 |
JPH0725749B2 (ja) | 1995-03-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3772905D1 (de) | Alpha-alkyl-4-amino-3-chinolin-methanole und 1-(4-aralkylamino-3-chinolyl)alkanone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
ATE163012T1 (de) | N-substituierte 4-pyrimidinamine und - pyrimidindiamine, verfahren zu ihrer herstellung und ihre anwendung als arzneimittel | |
DE69031259D1 (de) | Mit Physostigmine verwandte N-aminocarbamate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel | |
DE68902386D1 (de) | N-pyridinyl-9h-carbazol-9-amine, verfahren zu ihrer herstellung und ihre verwendung als medikamente. | |
DE3780015D1 (de) | Kondensierte heterocyclische tetrahydroaminochinolinole und verwandte verbindungen, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
ATE111899T1 (de) | 1,2,3,4-tetrahydro-1,9-acridindiamine, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente. | |
ATE115133T1 (de) | (1,2,3,4-tetrahydro-9-acridinimino)cyclohexan- carbonsäure und verwandte verbindungen, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente. | |
DE68906647D1 (de) | Hydroxy-1,2,3,4-tetrahydroaminoacridine, verfahren fuer ihre herstellung und ihre verwendung als arzneimittel. | |
ATE122047T1 (de) | 4,5,5a,6-tetrahydro-3h-isoxyzolo(5,4,3- k1)acridinderivate, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente. | |
PT82187A (en) | Benzo<c>-1,5-naphthyridines a process and intermediates for their preparation and their use as medicaments |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |