DK1626979T3 - Genetisk modificeret gærart og fremgangsmåder til fermentering, hvor den genetisk modificerede gær anvendes - Google Patents

Genetisk modificeret gærart og fremgangsmåder til fermentering, hvor den genetisk modificerede gær anvendes

Info

Publication number
DK1626979T3
DK1626979T3 DK04751126.6T DK04751126T DK1626979T3 DK 1626979 T3 DK1626979 T3 DK 1626979T3 DK 04751126 T DK04751126 T DK 04751126T DK 1626979 T3 DK1626979 T3 DK 1626979T3
Authority
DK
Denmark
Prior art keywords
genetically modified
modified yeast
fermentation
methods
species
Prior art date
Application number
DK04751126.6T
Other languages
English (en)
Inventor
Vineet Rajgarhia
Chris Miller
Kari Koivuranta
Merja Penttilae
Pirkko Suominen
Aristos Aristidou
Stacey Olson
Laura Ruohonen
Marja Ilmen
Original Assignee
Cargill Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill Inc filed Critical Cargill Inc
Application granted granted Critical
Publication of DK1626979T3 publication Critical patent/DK1626979T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/14—Multiple stages of fermentation; Multiple types of microorganisms or re-use of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C12N9/248—Xylanases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01009—D-Xylulose reductase (1.1.1.9), i.e. xylitol dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01—Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/01017—Xylulokinase (2.7.1.17)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02—Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02003—Phosphoglycerate kinase (2.7.2.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01037—Xylan 1,4-beta-xylosidase (3.2.1.37)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01001—Pyruvate decarboxylase (4.1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y501/00—Racemaces and epimerases (5.1)
    • C12Y501/03—Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • C12Y501/03002—UDP-glucose 4-epimerase (5.1.3.2), i.e. UDP-galactose 4-epimerase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y503/00—Intramolecular oxidoreductases (5.3)
    • C12Y503/01—Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01005—Xylose isomerase (5.3.1.5)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK04751126.6T 2003-05-02 2004-05-03 Genetisk modificeret gærart og fremgangsmåder til fermentering, hvor den genetisk modificerede gær anvendes DK1626979T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46772703P 2003-05-02 2003-05-02
PCT/US2004/013592 WO2004099381A2 (en) 2003-05-02 2004-05-03 Genetically modified yeast species and fermentation processes using genetically modified yeast

Publications (1)

Publication Number Publication Date
DK1626979T3 true DK1626979T3 (da) 2012-07-09

Family

ID=33435110

Family Applications (4)

Application Number Title Priority Date Filing Date
DK10183744.1T DK2338895T3 (da) 2003-05-02 2004-05-03 Genetisk modificerede gærspecies og fermenteringsproces under anvendelse af genetisk modificeret gær
DK10183712.8T DK2301949T3 (da) 2003-05-02 2004-05-03 Genetisk modificerede gærarter og fermenteringsfremgangsmåder under anvendelse af genetisk modificeret gær
DK10183662.5T DK2345662T3 (da) 2003-05-02 2004-05-03 Genetisk modificerede gærarter og fermenteringsprocesser anvendende genetisk modificeret gær
DK04751126.6T DK1626979T3 (da) 2003-05-02 2004-05-03 Genetisk modificeret gærart og fremgangsmåder til fermentering, hvor den genetisk modificerede gær anvendes

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DK10183744.1T DK2338895T3 (da) 2003-05-02 2004-05-03 Genetisk modificerede gærspecies og fermenteringsproces under anvendelse af genetisk modificeret gær
DK10183712.8T DK2301949T3 (da) 2003-05-02 2004-05-03 Genetisk modificerede gærarter og fermenteringsfremgangsmåder under anvendelse af genetisk modificeret gær
DK10183662.5T DK2345662T3 (da) 2003-05-02 2004-05-03 Genetisk modificerede gærarter og fermenteringsprocesser anvendende genetisk modificeret gær

Country Status (12)

Country Link
US (5) US7943366B2 (da)
EP (4) EP1626979B1 (da)
JP (1) JP4711955B2 (da)
CN (2) CN1922198B (da)
AU (1) AU2004236724B2 (da)
BR (1) BRPI0409954B1 (da)
CA (1) CA2524387C (da)
DK (4) DK2338895T3 (da)
ES (4) ES2586618T3 (da)
PL (4) PL2345662T3 (da)
WO (1) WO2004099381A2 (da)
ZA (1) ZA200509697B (da)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
BRPI0306740B1 (pt) 2002-01-23 2019-08-27 C5 Yeast Company B V célula hospedeira transformada com um construto de ácido nucléico e processo para a produção de etanol
BRPI0513437A (pt) * 2004-07-16 2008-05-06 Univ Delft Tech célula hospedeira eucariótica com a capacidade para isomerizar diretamente xilose em xilulose, e, processos para produzir etanol e um produto de fermentação
US20150328347A1 (en) 2005-03-24 2015-11-19 Xyleco, Inc. Fibrous materials and composites
US7708214B2 (en) 2005-08-24 2010-05-04 Xyleco, Inc. Fibrous materials and composites
EP1885842A4 (en) 2005-06-02 2009-06-10 Cargill Inc GENETICALLY MODIFIED YEAST OF ISSATCHENKIAORIENTALIS SPECIES AND CLOSELY BINDED SPECIES AND PROCESSES OF FERMENTATION USING THE SAME
EP1929009A2 (en) 2005-09-22 2008-06-11 Tate & Lyle Ingredients Americas, Inc. Improved strains for the production of organic acids
CA2631036A1 (en) 2005-11-23 2007-10-18 Natureworks Llc Lactic acid-producing yeast cells having nonfunctional l-or d-lactate: ferricytochrome c oxidoreductase gene
EP2586313B1 (en) 2006-03-13 2017-02-22 Cargill, Incorporated Fermentation process using yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol
US20080090283A1 (en) * 2006-10-13 2008-04-17 Rowan Universtity Ethanol resistant and furfural resistant strains of E. coli FBR5 for production of ethanol from cellulosic biomass
CN101463328B (zh) * 2007-12-19 2011-06-29 中国科学院微生物研究所 一株利用木糖发酵产乙醇的代谢工程酵母菌
US8455239B2 (en) * 2007-12-23 2013-06-04 Gevo, Inc. Yeast organism producing isobutanol at a high yield
BRPI0821519A2 (pt) 2007-12-27 2015-06-16 Gevo Inc Recuperação de alcoois superiores a partir de soluções aquosas diluída
US8440449B2 (en) * 2008-09-30 2013-05-14 The United States Of America, As Represented By The Secretary Of Agriculture Transformed Saccharomyces cerevisiae engineered for xylose utilization
CA3092340A1 (en) * 2008-11-21 2010-05-27 Universiteit Stellenbosch Yeast expressing cellulases for simultaneous saccharification and fermentation using cellulose
GB0822937D0 (en) 2008-12-16 2009-01-21 Terranol As Microorganism
US9334488B2 (en) 2008-12-24 2016-05-10 Dsm Ip Assets B.V. Xylose isomerase genes and their use in fermentation of pentose sugars
US20100311137A1 (en) 2009-06-08 2010-12-09 Ut-Battelle, Llc Microorganisms Having Enhanced Tolerance To Inhibitors and Stress
EP2446043A4 (en) * 2009-06-22 2013-02-13 Gevo Inc YEAST ORGANISMS FOR THE MANUFACTURE OF ISOBUTANOL
US20120184020A1 (en) * 2009-07-09 2012-07-19 Verdezyne, Inc. Engineered microorganisms with enhanced fermentation activity
CA2785276C (en) 2009-12-22 2019-04-23 Kabushiki Kaisha Toyota Chuo Kenkyusho Xylose isomerase and use thereof
JP5804378B2 (ja) * 2010-02-09 2015-11-04 国立大学法人山口大学 クルイベロマイセス・マルシアヌス由来の高発現プロモーター
PL2561064T3 (pl) * 2010-04-21 2018-03-30 Dsm Ip Assets B.V. Komórka odpowiednia do fermentacji kompozycji mieszanych cukrów
WO2011149353A1 (en) 2010-05-27 2011-12-01 C5 Yeast Company B.V. Yeast strains engineered to produce ethanol from acetic acid and glycerol
WO2011153516A2 (en) 2010-06-03 2011-12-08 Mascoma Corporation Yeast expressing saccharolytic enzymes for consolidated bioprocessing using starch and cellulose
CA2819315C (en) * 2010-11-11 2015-11-03 Toyota Jidosha Kabushiki Kaisha Method for producing ethanol using recombinant yeast strain
ES2532508T3 (es) 2010-11-18 2015-03-27 Dsm Ip Assets B.V. Cepas de levaduras manipuladas para producir etanol a partir de glicerol
BR112013012130A2 (pt) 2010-11-22 2017-10-31 Cargill Inc composições e métodos para titulação aumentada de etanol a partir de biomassa
EP2668281A4 (en) 2011-01-25 2015-08-26 Cargill Inc COMPOSITIONS AND METHODS OF SUCCINATE MANUFACTURE
CN102174549B (zh) 2011-02-22 2012-10-10 山东大学 一种编码木糖异构酶的核酸分子及其编码的木糖异构酶
WO2012125027A1 (en) 2011-03-14 2012-09-20 Dsm Ip Assets B.V. Yeast strains that ferment uronic acids
DK2697252T3 (da) 2011-04-11 2016-12-12 Cargill Inc Sammensætninger og fremgangsmåder til forøget ethanol produktion fra biomasse
EP2546336A1 (en) 2011-07-11 2013-01-16 DSM IP Assets B.V. Yeast strains that consume uronic acids and produce fermentation products such as ethanol
CN102304541A (zh) * 2011-08-17 2012-01-04 中国药科大学 一种含组成型启动子pPGK和G418抗性基因的酿酒酵母表达载体及其构建方法
EP2785849B1 (en) 2011-11-30 2017-09-27 DSM IP Assets B.V. Yeast strains engineered to produce ethanol from acetic acid and glycerol
CN104039970A (zh) 2012-01-13 2014-09-10 东丽株式会社 化学品的制造方法
US10378029B2 (en) 2012-01-13 2019-08-13 Toray Industries, Inc. Method of producing chemical substance
DK2806754T3 (da) 2012-01-23 2019-02-18 Dsm Ip Assets Bv Diterpen-fremstilling
CN102719481B (zh) * 2012-06-14 2014-11-05 中国科学院微生物研究所 一种将多个基因同时导入微生物基因组的方法
KR101576186B1 (ko) * 2012-06-26 2015-12-10 한국생명공학연구원 에탄올 생산 경로가 봉쇄된 클루이베로마이세스 막시아누스 균주 및 이의 용도
EP2877568B1 (en) 2012-07-25 2021-04-28 Cargill, Incorporated Yeast cells having reductive tca pathway from pyruvate to succinate and overexpressing an exogenous nad(p)+ transhydrogenase enzyme
IN2015DN01041A (da) 2012-08-28 2015-06-26 Dsm Ip Assets Bv
WO2014033019A1 (en) 2012-08-28 2014-03-06 Dsm Ip Assets B.V. Yeast strains engineered to produce ethanol from acetate
CN104797708A (zh) 2012-08-29 2015-07-22 拉勒曼德匈牙利流动性管理有限责任公司 酵母中用于木质纤维素衍生的寡聚物cbp的酶的表达
US8748152B1 (en) 2012-09-14 2014-06-10 The United States Of America, As Represented By The Secretary Of Agriculture Prevotella ruminicola xylose isomerase and co-expression with xylulokinase in yeast for xylose fermentation
US20140178954A1 (en) 2012-12-20 2014-06-26 E I Du Pont De Nemours And Company Expression of xylose isomerase activity in yeast
US8669076B1 (en) 2013-03-11 2014-03-11 E I Du Pont De Nemours And Company Cow rumen xylose isomerases active in yeast cells
US9187743B2 (en) 2013-03-11 2015-11-17 E I Du Pont De Nemours And Company Bacterial xylose isomerases active in yeast cells
JP6027559B2 (ja) 2013-03-28 2016-11-16 株式会社豊田中央研究所 キシロースイソメラーゼ活性を有するタンパク質及びその利用
TW201437367A (zh) 2013-03-29 2014-10-01 Far Eastern New Century Corp 可利用五碳糖及六碳糖生產乳酸之酵母菌
FI20135333L (fi) * 2013-04-05 2014-10-06 Teknologian Tutkimuskeskus Vtt Oy Hapon / happojen ja alkoholin tuotto sokereista käyttämällä hiivaa
DK3004366T3 (da) 2013-05-31 2019-05-20 Dsm Ip Assets Bv Mikroorganismer til diterpenproduktion
EP3885443A1 (en) 2013-07-15 2021-09-29 DSM IP Assets B.V. Diterpene production
US20160185813A1 (en) 2013-07-31 2016-06-30 Dsm Ip Assets B.V. Recovery of steviol glycosides
CN104419716B (zh) * 2013-08-27 2017-12-29 天津大学 一种标准化、高精度、通用的功能模块构建方法
AR097480A1 (es) 2013-08-29 2016-03-16 Dsm Ip Assets Bv Células de levadura convertidoras de glicerol y ácido acético con una conversión de ácido acético mejorada
CN103421698B (zh) * 2013-09-05 2015-04-22 中国科学技术大学 木糖醇高温高产工程菌株的构建及应用
US20180030482A1 (en) 2014-04-18 2018-02-01 Moralco B.V. Use of acetaldehyde in the fermentative production of ethanol
BR102014027233A2 (pt) * 2014-10-30 2016-05-24 Biocelere Agroindustrial Ltda cassete de expressão, micro-organismo geneticamente modificado para expressão de xilose isomerase, processo para produção de biocombustíveis e/ou bioquímicos e biocombustível e/ou bioquímicos produzidos
TWI551688B (zh) * 2015-02-04 2016-10-01 遠東新世紀股份有限公司 發酵纖維素水解液來生成乙醇的方法
CN115851470A (zh) 2015-03-16 2023-03-28 帝斯曼知识产权资产管理有限公司 Udp-糖基转移酶
EP3274448B1 (en) 2015-03-23 2021-08-11 DSM IP Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
CN107666834B (zh) 2015-04-03 2021-08-24 帝斯曼知识产权资产管理有限公司 甜菊醇糖苷
CA2980649A1 (en) 2015-04-21 2016-10-27 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthase
CN107820394A (zh) 2015-07-10 2018-03-20 帝斯曼知识产权资产管理有限公司 甜菊醇糖苷组合物
JP6977231B2 (ja) 2015-07-13 2021-12-08 マラ リニューアブルズ コーポレーション Ｃ５有機炭素の微生物による代謝の増強
EP3332004A1 (en) 2015-08-05 2018-06-13 Cargill, Incorporated Xylose isomerase-modified yeast strains and methods for bioproduct production
CN107922913B (zh) 2015-08-13 2022-04-05 帝斯曼知识产权资产管理有限公司 甜菊醇糖苷转运
EP4043558A3 (en) 2015-10-05 2022-11-16 DSM IP Assets B.V. Kaurenoic acid hydroxylases
WO2017091610A1 (en) 2015-11-24 2017-06-01 Cargill, Incorporated Genetically modified yeasts and fermentation processes using genetically modified yeasts
SG11201804966VA (en) * 2015-12-17 2018-07-30 Evonik Degussa China Co Ltd Gene cassette for homologous recombination knock-out in yeast cells
BR112018070645A2 (pt) 2016-04-08 2019-02-05 Du Pont células de levedura recombinante, métodos para produzir uma célula de levedura e método para produzir um composto alvo
KR101827822B1 (ko) 2016-06-07 2018-03-23 강원대학교 산학협력단 자일리톨 생산능이 향상된 클루이베로마이세스 마르시아누스 36907-fmel1 (kctc18459p) 및 이를 이용한 자일리톨의 생산방법
CA3032656A1 (en) 2016-08-09 2018-02-15 Dsm Ip Assets B.V. Crystallization of steviol glycosides
WO2018029274A1 (en) 2016-08-09 2018-02-15 Dsm Ip Assets B.V. Crystallization of steviol glycosides
WO2018078014A1 (en) 2016-10-27 2018-05-03 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthases
WO2018104238A1 (en) 2016-12-08 2018-06-14 Dsm Ip Assets B.V. Kaurenoic acid hydroxylases
BR112019013007A2 (pt) 2016-12-21 2019-10-08 Creatus Biosciences Inc organismo microbiano não natural, método de produção de um composto bioderivado, composto bioderivado e composição
WO2018114995A1 (en) 2016-12-22 2018-06-28 Dsm Ip Assets B.V. Fermentation process for producing steviol glycosides
CN110892068B (zh) 2017-06-27 2024-03-08 帝斯曼知识产权资产管理有限公司 Udp-糖基转移酶
US11718820B2 (en) 2017-08-17 2023-08-08 Cargill, Incorporated Genetically modified haploid Issatchenkia orientalis
CN112004930A (zh) 2018-03-27 2020-11-27 巴斯夫欧洲公司 木糖代谢酵母
CN112424218A (zh) 2018-04-30 2021-02-26 帝斯曼知识产权资产管理有限公司 甜菊糖苷转运
EP4165063A1 (en) 2020-06-15 2023-04-19 Melio Peptide Systems Inc. Microorganisms and methods for reducing bacterial contamination
EP4232568A1 (en) 2020-10-22 2023-08-30 DSM IP Assets B.V. Microorganisms for diterpene production

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL39710A (en) 1972-06-19 1975-04-25 Imi Inst For Res & Dev Recovery of acids from aqueous solutions by solvent extraction
US4771001A (en) 1986-03-27 1988-09-13 Neurex Corp. Production of lactic acid by continuous fermentation using an inexpensive raw material and a simplified method of lactic acid purification
US5866382A (en) 1990-04-06 1999-02-02 Xyrofin Oy Xylose utilization by recombinant yeasts
US5210296A (en) 1990-11-19 1993-05-11 E. I. Du Pont De Nemours And Company Recovery of lactate esters and lactic acid from fermentation broth
US5132456A (en) 1991-05-07 1992-07-21 The Regents Of The University Of California Sorption of carboxylic acid from carboxylic salt solutions at PHS close to or above the pKa of the acid, with regeneration with an aqueous solution of ammonia or low-molecular-weight alkylamine
FI913197A0 (fi) * 1991-07-01 1991-07-01 Xyrofin Oy Nya jaeststammar med reducerad foermaoga att metabolisera xylitol, foerfarande foer bildande av dessa och deras anvaendning vid framstaellning av xylitol.
US5420304A (en) 1992-03-19 1995-05-30 Biopak Technology, Ltd. Method to produce cyclic esters
AT398982B (de) 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US5510526A (en) 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
FR2712147B1 (fr) 1993-11-08 1996-02-02 Agronomique Inst Nat Rech Produit alimentaire, obtention et application à la fabrication de jus de fruits ou de vin.
US5789210A (en) 1993-11-08 1998-08-04 Purdue Research Foundation Recombinant yeasts for effective fermentation of glucose and xylose
IL109003A (en) 1994-03-16 1999-09-22 Yissum Res Dev Co Process and extractant composition for extracting water-soluble carboxylic and mineral acids
IN191596B (da) 1996-05-06 2003-12-06 Purdue Research Foundation
US6717014B1 (en) * 1996-06-28 2004-04-06 Fmc Corporation Processes for preparing haloamines and tertiary aminoalkylorganometallic compounds
IT1294728B1 (it) * 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
WO1999054477A2 (en) * 1998-04-20 1999-10-28 Forskarpatent I Syd Ab Genetically engineered yeast and mutants thereof for the efficient fermentation of lignocellulose hydrolysates
SE9901298D0 (sv) 1999-04-09 1999-04-09 Forskarpatent I Syd Ab Xylose isomerase with improved kinetic properties
WO2000071738A1 (en) 1999-05-21 2000-11-30 Cargill Dow Llc Methods and materials for the synthesis of organic products
US6762339B1 (en) 1999-05-21 2004-07-13 3M Innovative Properties Company Hydrophilic polypropylene fibers having antimicrobial activity
EP1301618A1 (en) * 2000-07-13 2003-04-16 Danisco Sweeteners Oy Method for the production of xylitol
AU2002237676A1 (en) 2000-11-22 2002-06-03 Cargill Dow Polymers, Llc Methods and materials for the synthesis of organic products
CA2474152A1 (en) 2001-11-23 2003-06-19 Cargill Dow Llc Methods and materials for the production of organic products in cells of candida species
BRPI0306740B1 (pt) * 2002-01-23 2019-08-27 C5 Yeast Company B V célula hospedeira transformada com um construto de ácido nucléico e processo para a produção de etanol
JP2005528112A (ja) 2002-05-30 2005-09-22 カーギル ダウ エルエルシー 酵母におけるｄ−乳酸の生産方法およびその材料
SE0302421D0 (sv) * 2003-09-11 2003-09-11 Forskarpatent I Syd Ab Construction of new xylose utilizing Saccharomyces cerevisiae strain
EP1885842A4 (en) * 2005-06-02 2009-06-10 Cargill Inc GENETICALLY MODIFIED YEAST OF ISSATCHENKIAORIENTALIS SPECIES AND CLOSELY BINDED SPECIES AND PROCESSES OF FERMENTATION USING THE SAME
CA2631036A1 (en) * 2005-11-23 2007-10-18 Natureworks Llc Lactic acid-producing yeast cells having nonfunctional l-or d-lactate: ferricytochrome c oxidoreductase gene
JP5219074B2 (ja) * 2008-01-24 2013-06-26 独立行政法人産業技術総合研究所 キシロース発酵能が優れた六炭糖・五炭糖同時発酵酵母およびそれを用いたエタノールの高効率生産方法
WO2011019894A1 (en) * 2009-08-12 2011-02-17 Gevo, Inc. Cytosolic isobutanol pathway localization for the production of isobutanol

Also Published As

Publication number Publication date
BRPI0409954A (pt) 2006-04-25
US8623633B2 (en) 2014-01-07
EP2301949A1 (en) 2011-03-30
EP1626979A2 (en) 2006-02-22
CN1922198A (zh) 2007-02-28
DK2301949T3 (da) 2015-07-20
EP2345662A1 (en) 2011-07-20
US9758799B2 (en) 2017-09-12
EP2345662B1 (en) 2016-06-22
US20110287506A1 (en) 2011-11-24
WO2004099381A2 (en) 2004-11-18
US20140080192A1 (en) 2014-03-20
ZA200509697B (en) 2007-03-28
CA2524387A1 (en) 2004-11-18
PL2301949T3 (pl) 2015-10-30
US20060234364A1 (en) 2006-10-19
DK2338895T3 (da) 2013-09-08
US9410158B2 (en) 2016-08-09
AU2004236724B2 (en) 2008-07-10
JP2006525029A (ja) 2006-11-09
PL2345662T3 (pl) 2016-11-30
DK2345662T3 (da) 2016-08-15
US20110287505A1 (en) 2011-11-24
EP2338895B1 (en) 2013-08-14
EP1626979A4 (en) 2006-11-15
US7943366B2 (en) 2011-05-17
PL2338895T3 (pl) 2013-11-29
WO2004099381A3 (en) 2005-05-06
US20160340697A1 (en) 2016-11-24
CA2524387C (en) 2012-12-04
CN1922198B (zh) 2012-07-11
CN102703336A (zh) 2012-10-03
EP2338895A1 (en) 2011-06-29
BRPI0409954B1 (pt) 2016-07-12
PL1626979T3 (pl) 2012-09-28
US8440451B2 (en) 2013-05-14
EP2301949B1 (en) 2015-06-24
EP1626979B1 (en) 2012-06-06
ES2586618T3 (es) 2016-10-17
ES2543385T3 (es) 2015-08-18
JP4711955B2 (ja) 2011-06-29
ES2426966T3 (es) 2013-10-28
ES2385561T3 (es) 2012-07-26
AU2004236724A1 (en) 2004-11-18

Similar Documents

Publication Publication Date Title
DK1626979T3 (da) Genetisk modificeret gærart og fremgangsmåder til fermentering, hvor den genetisk modificerede gær anvendes
DE60317699D1 (de) Fermentationsverfahren und -zusammensetzungen
ITRM20040638A1 (it) Gel piastrinico semisintetico e metodo per la sua preparazione.
IS7992A (is) Dýralaus frumuræktunar aðferð
DK1511734T3 (da) Forbindelser, præparater og fremgangsmåder
DK1651401T3 (da) Partikelformigt trækonserveringsmiddel og fremgangsmåde til fremstilling deraf
ZA200711038B (en) Genetically modified yeast of the species Issatchenkia orientalis and closely related species and fermentation processes using same
IL173165A0 (en) Cell cultivation and breeding method
NO20053357D0 (no) Dyrkingsmedium, dyrkingsmetode og de oppnadde myoblaster og deres anvendelse.
IS8456A (is) Fyrirtækjamatsbúnaður og fyrirtækjamatsforrit
DK1715893T3 (da) Direkte kompressionsformulering og fremgangsmåde
EP1660638A4 (en) LIPOPARTICLES COMPRISING PROTEINS, AND METHODS OF MAKING AND USING SAME LIPOPARTICLES
NO20055018D0 (no) Anti-amyolide antistoffer, sammensetninger, fremgangsmater og anvendelser
IS7684A (is) Ný efnasambönd, blöndur og aðferðir til að meðhöndla bólgusjúkdóma og -ástand
DE602004010273D1 (de) Amplifikationsmethode
DK1641910T3 (da) Glucanaser, nucleinsyrer, som koder for disse, og fremgangsmåder til at fremstille og benytte disse
NO20055686L (no) Sammensetning, fremgangsmate til fremstilling derav, og anvendelse derav.
EP1623227A4 (en) PROTEINS, SENSORS AND METHODS FOR CHARACTERIZING SUBSTANCES TO BE ANALYZED USING THESE PROTEINS AND THESE SENSORS
DK1791958T3 (da) Gær/bakterie-to-hybridsystem og fremgangsmåder til brug deraf
IS7798A (is) Efnasambönd, lyfjablöndur og aðferðir
DK1711502T3 (da) Fremgangsmåder til at fremstille 3-O-beskyttede-morphinoner og 3-O-beskyttede morphinon-dienol-carboxylater
DK1668125T3 (da) Modificerede enzymer, fremgangsmåde til fremstilling af modificerede enzymer og anvendelser deraf
DK1601744T3 (da) Forgasningsapparat og fremgangsmåde
IS8489A (is) Umritunarstillar og aðferðir þeirra
DK1768691T3 (da) Aequorinholdige præparater og fremgangsmåder til anvendelse af samme