DK15681A - Fremgangsmaade til fremstilling af cyclohexenderivater - Google Patents

Fremgangsmaade til fremstilling af cyclohexenderivater

Info

Publication number
DK15681A
DK15681A DK15681A DK15681A DK15681A DK 15681 A DK15681 A DK 15681A DK 15681 A DK15681 A DK 15681A DK 15681 A DK15681 A DK 15681A DK 15681 A DK15681 A DK 15681A
Authority
DK
Denmark
Prior art keywords
cyclohe
procedure
preparation
exchange derivatives
derivatives
Prior art date
Application number
DK15681A
Other languages
Danish (da)
English (en)
Inventor
H Bruderer
A E Fischli
R Pfister
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK15681A publication Critical patent/DK15681A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Indole Compounds (AREA)
DK15681A 1980-01-29 1981-01-14 Fremgangsmaade til fremstilling af cyclohexenderivater DK15681A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH72480A CH644580A5 (de) 1980-01-29 1980-01-29 Cyclohexen-derivate.

Publications (1)

Publication Number Publication Date
DK15681A true DK15681A (da) 1981-07-30

Family

ID=4193699

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15681A DK15681A (da) 1980-01-29 1981-01-14 Fremgangsmaade til fremstilling af cyclohexenderivater

Country Status (32)

Country Link
US (2) US4336268A (xx)
EP (1) EP0033156B1 (xx)
JP (1) JPS56120650A (xx)
KR (6) KR850000626B1 (xx)
AR (1) AR227906A1 (xx)
AT (2) ATE9895T1 (xx)
AU (1) AU540697B2 (xx)
BR (1) BR8100484A (xx)
CA (1) CA1161064A (xx)
CH (1) CH644580A5 (xx)
CS (6) CS220347B2 (xx)
DE (2) DE3102603A1 (xx)
DK (1) DK15681A (xx)
ES (6) ES8301200A1 (xx)
FI (1) FI801147A (xx)
FR (1) FR2479815A1 (xx)
GB (1) GB2068373B (xx)
HU (1) HU182280B (xx)
IE (1) IE50885B1 (xx)
IL (1) IL61961A (xx)
IT (1) IT1135001B (xx)
LU (1) LU83096A1 (xx)
MC (1) MC1365A1 (xx)
NL (1) NL8100403A (xx)
NO (1) NO149958C (xx)
NZ (1) NZ196086A (xx)
PH (1) PH16098A (xx)
PT (1) PT72415B (xx)
SE (1) SE8100403L (xx)
YU (1) YU332180A (xx)
ZA (1) ZA81459B (xx)
ZW (1) ZW31480A1 (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372919B1 (en) * 2001-01-11 2002-04-16 Dov Pharmaceutical, Inc. (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent
US20060173064A1 (en) * 2001-08-24 2006-08-03 Lippa Arnold S (-)-1-(3,4-Dichlorophenyl)-3-azabi cyclo[3.1.0]hexane, compositions thereof, and uses for treating alcohol-related disorders
US6569887B2 (en) * 2001-08-24 2003-05-27 Dov Pharmaceuticals Inc. (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake
US20080081834A1 (en) 2002-07-31 2008-04-03 Lippa Arnold S Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders
US20070043100A1 (en) * 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
US20060100263A1 (en) * 2004-11-05 2006-05-11 Anthony Basile Antipyretic compositions and methods
PL2719384T3 (pl) 2005-07-27 2019-02-28 Otsuka America Pharmaceutical, Inc. Nowe 1-naftylo-3-azabicyklo[3.1.0]heksany: wytwarzanie i zastosowanie do leczenia zaburzeń neuropsychiatrycznych
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) * 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US20080269348A1 (en) * 2006-11-07 2008-10-30 Phil Skolnick Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use
WO2008153937A2 (en) * 2007-06-06 2008-12-18 Dov Pharmaceutical, Inc. Novel 1- heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US20140206740A1 (en) 2011-07-30 2014-07-24 Neurovance, Inc. Use Of (1R,5S)-(+)-(Napthalen-2-yl)-3-Azabicyclo[3.1.0]Hexane In The Treatment Of Conditions Affected By Monoamine Neurotransmitters

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH249047A (de) * 1944-03-20 1947-05-31 Ag J R Geigy Verfahren zur Darstellung eines basischen Esters einer 1-Aryl-cycloalkyl-1-carbonsäure.
CH249052A (de) * 1944-03-20 1947-05-31 Ag J R Geigy Verfahren zur Darstellung eines basischen Amids einer 1-Aryl-cycloalkyl-1-carbonsäure.
US2647122A (en) * 1948-10-01 1953-07-28 Sterling Drug Inc Tertiary amines and process of preparing them
US3109845A (en) * 1960-02-04 1963-11-05 Thomae Gmbh Dr K 1-cyclohexyl, 1-cyclohexenyl, 1-furyl, and 1-thienyl, tertiary amino substituted methanes
DE1518545A1 (de) * 1965-04-01 1970-01-15 Boehringer Mannheim Gmbh Verfahren zur Herstellung neuer Phenylcyclohexylalkylamine und ihrer Salze
DE1518663A1 (de) * 1965-08-02 1969-12-18 Gruenenthal Chemie Basisch substituierte Cycloalken-derivate und Verfahren zu ihrer Herstellung
US3408396A (en) * 1965-10-22 1968-10-29 Colgate Palmolive Co alpha-cyclohexyl-3, 4-disubstituted-phenyl acetamides
US3485873A (en) * 1966-12-21 1969-12-23 Sterling Drug Inc N-benzyl-n-methyl-omega-phenyl-omega-cycloalkyl-lower-alkylamines
US3737451A (en) * 1970-09-23 1973-06-05 Sandoz Ag Cis-3,4-diaryl-cyclopentylidene-and 1-cyclopentene-1-acetic acids and derivatives
US4053637A (en) * 1971-06-11 1977-10-11 Astra Lakemedal Aktiebolag Compounds of diphenylcyclopentylamine type and methods for their uses
CA1130318A (en) * 1978-10-11 1982-08-24 Peter M. Muller Cyclohexadiene derivatives

Also Published As

Publication number Publication date
ES8301878A1 (es) 1982-12-16
EP0033156A2 (de) 1981-08-05
KR850000626B1 (ko) 1985-05-06
ATE9895T1 (de) 1984-11-15
GB2068373B (en) 1983-11-30
YU332180A (en) 1983-10-31
AT376654B (de) 1984-12-27
CA1161064A (en) 1984-01-24
IT8119047A0 (it) 1981-01-08
KR840001551B1 (ko) 1984-10-05
ES506687A0 (es) 1982-12-16
EP0033156B1 (de) 1984-10-17
PT72415B (en) 1982-07-26
MC1365A1 (fr) 1981-10-23
BR8100484A (pt) 1981-08-18
KR830005105A (ko) 1983-07-23
KR850002003A (ko) 1985-04-10
PH16098A (en) 1983-06-24
AU540697B2 (en) 1984-11-29
ES506684A0 (es) 1983-10-16
AU6671981A (en) 1981-08-06
IL61961A0 (en) 1981-02-27
CS219940B2 (en) 1983-03-25
ZA81459B (en) 1982-02-24
JPS56120650A (en) 1981-09-22
CS219941B2 (en) 1983-03-25
US4448991A (en) 1984-05-15
DE3166656D1 (en) 1984-11-22
FR2479815B1 (xx) 1984-02-17
IT1135001B (it) 1986-08-20
FR2479815A1 (fr) 1981-10-09
IE810153L (en) 1981-07-29
KR840001554B1 (ko) 1984-10-05
NL8100403A (nl) 1981-08-17
US4336268A (en) 1982-06-22
CS219942B2 (en) 1983-03-25
IL61961A (en) 1984-05-31
SE8100403L (sv) 1981-07-30
CS219943B2 (en) 1983-03-25
KR850000627B1 (ko) 1985-05-06
ES8301885A1 (es) 1982-12-16
LU83096A1 (de) 1982-09-10
AR227906A1 (es) 1982-12-30
NO810297L (no) 1981-07-30
NO149958C (no) 1984-07-25
EP0033156A3 (en) 1982-03-17
CH644580A5 (de) 1984-08-15
FI801147A (fi) 1981-07-30
PT72415A (en) 1981-02-01
IE50885B1 (en) 1986-08-06
KR840001553B1 (ko) 1984-10-05
DE3102603A1 (de) 1981-12-10
ZW31480A1 (en) 1981-09-02
HU182280B (en) 1983-12-28
ES8301883A1 (es) 1982-12-16
ES498866A0 (es) 1982-12-01
ES506688A0 (es) 1982-12-16
ATA35581A (de) 1984-05-15
ES506686A0 (es) 1982-12-16
KR840001552B1 (ko) 1984-10-05
NZ196086A (en) 1984-08-24
ES8301200A1 (es) 1982-12-01
ES8301884A1 (es) 1982-12-16
ES8400079A1 (es) 1983-10-16
GB2068373A (en) 1981-08-12
NO149958B (no) 1984-04-16
ES506685A0 (es) 1982-12-16
CS219944B2 (en) 1983-03-25
CS220347B2 (en) 1983-03-25

Similar Documents

Publication Publication Date Title
DK534481A (da) Fremgangsmaade til fremstilling af 1-sulfo-2-oxoazetidinderivater
DK99781A (da) Fremgangsmaade til fremstilling af carboxtyrilderivater
DK2281A (da) Fremgangsmaade til fremstilling af tiazolinderivater
DK157876C (da) Analogifremgangsmaade til fremstilling af imidazo-rifamycin-derivater
DK300981A (da) Fremgangsmaade til fremstilling af imidazolderivater
DK112582A (da) Fremgangsmaade til fremstilling af triazolonderivater
DK435181A (da) Fremgangsmaade til fremstilling af thiazol-derivater
DK66582A (da) Fremgangsmaade til fremstilling af carbostyrilderivater
DK161581A (da) Fremgangsmaade til fremstilling af imidazolderivater
DK162524C (da) Analogifremgangsmaade til fremstilling af 5-alkylthio-tetrazolderivater
DK491582A (da) Fremgangsmaade til fremstilling af morphinanderivater
DK100281A (da) Fremgangsmaade til fremstilling af imidazolderivater
DK352082A (da) Fremgangsmaade til fremstilling af ergopeptinderivater
DK15681A (da) Fremgangsmaade til fremstilling af cyclohexenderivater
DK160555C (da) Fremgangsmaade til fremstilling af eburnamoninderivater
DK564781A (da) Fremgangsmaade til fremstilling af pyrazoloindazolderivater
DK116982A (da) Fremgangsmaade til fremstilling af alkylendioxybenzenderivater
DK554581A (da) Fremgangsmaade til fremstilling af alkylendioxybenzenderivater
DK172181A (da) Fremgangsmaade til fremstilling af 9-carbamoyl-9-aminoalkylfluoren-derivater
DK100181A (da) Fremgangsmaade til fremstilling af acylderivater af carnitin
DK565281A (da) Fremgangsmaade til fremstilling af quinolon-derivater
DK151956C (da) Analogifremgangsmaade til fremstilling af carbostyrilderivater
DK85281A (da) Fremgangsmaade til fremstilling af phenoxyderivater
DK448981A (da) Fremgangsmaade til fremstilling af 4-chinolinmethanderivater
DK424781A (da) Fremgangsmaade til fremstilling af quinolonderivater

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
AHB Application shelved due to non-payment