DK1529043T3 - Fremgangsmåde til fremstilling af 2-methylpiperazin-derivater - Google Patents

Fremgangsmåde til fremstilling af 2-methylpiperazin-derivater

Info

Publication number
DK1529043T3
DK1529043T3 DK03736405T DK03736405T DK1529043T3 DK 1529043 T3 DK1529043 T3 DK 1529043T3 DK 03736405 T DK03736405 T DK 03736405T DK 03736405 T DK03736405 T DK 03736405T DK 1529043 T3 DK1529043 T3 DK 1529043T3
Authority
DK
Denmark
Prior art keywords
preparation
relates
present
methylpiperazine
derivatives
Prior art date
Application number
DK03736405T
Other languages
Danish (da)
English (en)
Inventor
Claes Loefstroem
Alexander Paptchikhine
Emma Andersson
Alf Nygren
Tom Di Fleck
Magnus Cernerud
Helena Lundstroem
Margit Pelcman
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0201881A external-priority patent/SE0201881D0/xx
Priority claimed from SE0202041A external-priority patent/SE0202041D0/xx
Priority claimed from SE0202516A external-priority patent/SE0202516D0/xx
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Application granted granted Critical
Publication of DK1529043T3 publication Critical patent/DK1529043T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
DK03736405T 2002-06-19 2003-06-18 Fremgangsmåde til fremstilling af 2-methylpiperazin-derivater DK1529043T3 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
SE0201881A SE0201881D0 (sv) 2002-06-19 2002-06-19 Novel compounds, their use, and preparation
US39065602P 2002-06-21 2002-06-21
SE0202041A SE0202041D0 (sv) 2002-06-28 2002-06-28 Novel process
US40611902P 2002-08-26 2002-08-26
SE0202516A SE0202516D0 (sv) 2002-08-26 2002-08-26 Novel compounds, their use, and preparation
US41670102P 2002-10-07 2002-10-07

Publications (1)

Publication Number Publication Date
DK1529043T3 true DK1529043T3 (da) 2006-12-04

Family

ID=30004077

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03736405T DK1529043T3 (da) 2002-06-19 2003-06-18 Fremgangsmåde til fremstilling af 2-methylpiperazin-derivater
DK05023471T DK1645558T3 (da) 2002-06-19 2003-06-18 Piperazinylpyraziner som serotonin 5-HT2C receptormodulatorer

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK05023471T DK1645558T3 (da) 2002-06-19 2003-06-18 Piperazinylpyraziner som serotonin 5-HT2C receptormodulatorer

Country Status (16)

Country Link
EP (2) EP1645558B1 (de)
JP (4) JP4592417B2 (de)
CN (1) CN100334082C (de)
AT (2) ATE334980T1 (de)
AU (1) AU2003237746B8 (de)
CA (1) CA2485532C (de)
CY (1) CY1106225T1 (de)
DE (2) DE60321606D1 (de)
DK (2) DK1529043T3 (de)
ES (2) ES2307102T3 (de)
HK (1) HK1080079B (de)
NO (1) NO20050279D0 (de)
NZ (1) NZ536663A (de)
PT (2) PT1645558E (de)
SI (2) SI1529043T1 (de)
WO (1) WO2004000829A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2248524A3 (de) 2004-08-25 2011-03-09 Takeda Pharmaceutical Company Limited Mittel zur prävention/behandlung von stressbedingter harninkontinenz und vorsorgeuntersuchungsverfahren dafür
JP5528699B2 (ja) 2006-05-16 2014-06-25 武田薬品工業株式会社 縮合複素環化合物およびその用途
RU2464269C2 (ru) 2007-10-16 2012-10-20 Дайити Санкио Компани, Лимитед Пиримидилиндолиновое соединение
EP2789338A3 (de) 2007-11-15 2015-01-14 Takeda Pharmaceutical Company Limited Kondensiertes Pyridinderivat und seine Verwendung
KR101768234B1 (ko) 2009-06-15 2017-08-14 다케다 야쿠힌 고교 가부시키가이샤 피라지노옥사제핀 유도체
EP2510949A4 (de) 2009-12-11 2013-11-13 Astellas Pharma Inc Therapeutikum für fibromyalgie
GB201304811D0 (en) * 2013-03-15 2013-05-01 Proximagen Ltd Novel treatment for hypertension
JPWO2019131902A1 (ja) 2017-12-27 2020-12-10 武田薬品工業株式会社 腹圧性尿失禁および便失禁の治療薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06306075A (ja) * 1993-04-23 1994-11-01 Sanwa Kagaku Kenkyusho Co Ltd エトキシベンズアミド誘導体
BR0010783A (pt) * 1999-05-21 2002-04-09 Biovitrum Ab Novos compostos, seu uso e preparação
AR032318A1 (es) * 2000-04-13 2003-11-05 Pharmacia Corp Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa
DE60139021D1 (de) * 2000-11-20 2009-07-30 Biovitrum Ab Publ Piperazinylpyrazinverbindungen als antagonisten des serotonin-5-ht2-rezeptors

Also Published As

Publication number Publication date
JP2013116906A (ja) 2013-06-13
PT1645558E (pt) 2008-07-30
AU2003237746B8 (en) 2010-01-28
JP2010120949A (ja) 2010-06-03
JP2013227336A (ja) 2013-11-07
JP5378241B2 (ja) 2013-12-25
DE60307286D1 (de) 2006-09-14
SI1645558T1 (sl) 2008-10-31
NO20050279D0 (no) 2005-01-18
EP1529043B1 (de) 2006-08-02
EP1645558B1 (de) 2008-06-11
CN100334082C (zh) 2007-08-29
WO2004000829A1 (en) 2003-12-31
HK1080079A1 (en) 2006-04-21
JP4592417B2 (ja) 2010-12-01
DK1645558T3 (da) 2008-10-06
ES2307102T3 (es) 2008-11-16
CY1106225T1 (el) 2011-06-08
EP1529043A1 (de) 2005-05-11
AU2003237746B2 (en) 2009-12-17
HK1080079B (zh) 2008-03-14
CA2485532C (en) 2012-03-06
NZ536663A (en) 2007-05-31
AU2003237746A1 (en) 2004-01-06
ATE398119T1 (de) 2008-07-15
CA2485532A1 (en) 2003-12-31
PT1529043E (pt) 2006-12-29
DE60307286T2 (de) 2007-10-25
SI1529043T1 (sl) 2006-12-31
DE60321606D1 (de) 2008-07-24
EP1645558A1 (de) 2006-04-12
JP2005537316A (ja) 2005-12-08
ATE334980T1 (de) 2006-08-15
ES2270051T3 (es) 2007-04-01
CN1662523A (zh) 2005-08-31

Similar Documents

Publication Publication Date Title
BR0311494A (pt) Novos indóis substituìdos
SE0303180D0 (sv) Novel compounds
SE0302232D0 (sv) Novel Compounds
MXPA03011484A (es) Heteroarilos multiciclicos sustituidos con quinuclidinas para el tratamiento de enfermedades.
SE0203713D0 (sv) Novel compounds
EA200600317A1 (ru) Производные омега-карбоксиарилдифенилмочевины (варианты), фармацевтическая композиция (варианты) и способ лечения и предупреждения заболеваний и состояний с их использованием (варианты)
HK1080079A1 (en) A process for the preparation of 2-methylpiperazine derivative
DE502005008057D1 (de) Substituierte cyclopenten-verbindungen
WO2005075425A3 (en) Substituted bisarylurea derivatives as kinase inhibitors
JO2282B1 (en) Oxazole derivatives
SE0200979D0 (sv) New compounds
EA200601798A1 (ru) Замещенные соединения морфолина для лечения расстройств центральной нервной системы
TW200616979A (en) Non-nucleoside reverse transcriptase inhibitors
EA200600223A1 (ru) Замещённый 2-аминотетралины для лечения депрессии
EA200700909A1 (ru) Азаиндолкарбоксамиды
ATE307810T1 (de) Imidazol-2-carbonsäureamid derivate als raf- kinase-inhibitoren
ATE356621T1 (de) (s)-2-n-propylamino-5-hydroxytetralin als d3- agonistisches therapeutikum
TNSN04250A1 (en) Diphenyl azetidinones substituted by acidic groups, method for their production, medicaments containing said compounds and use thereof.
EA200601194A1 (ru) Новые производные бензофурана, используемые для профилактики или лечения нарушений, связанных с 5-ht-рецептором
DK1745010T3 (da) Substituerede cyklohexyl-1,4-diaminderivater
EA200700707A1 (ru) Производные 2-ациламинотиазола
BRPI0517734A (pt) derivados de 1-[(6,7-alcoxiquinoxalinil substituìdo) aminocarbonil]-4- (hetero) arilpiperazina
SE0101082D0 (sv) Novel use
EA200401432A1 (ru) Сложноэфирные производные декагидроизохинолин-3-карбоновой кислоты в качестве анальгетиков
ATE473737T1 (de) Verwendung von 2,3-dehydronaringenin-derivaten zur behandlung von entzündungsprozessen und diese derivate enthaltende pharmazeutische zusammensetzung