EA200700707A1 - Производные 2-ациламинотиазола - Google Patents
Производные 2-ациламинотиазолаInfo
- Publication number
- EA200700707A1 EA200700707A1 EA200700707A EA200700707A EA200700707A1 EA 200700707 A1 EA200700707 A1 EA 200700707A1 EA 200700707 A EA200700707 A EA 200700707A EA 200700707 A EA200700707 A EA 200700707A EA 200700707 A1 EA200700707 A1 EA 200700707A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- acylaminothiazole
- derivatives
- compounds
- receptor
- neurological
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Изобретение относится к соединениям формулы I, переменные которой определены в формуле изобретения, для применения в качестве лекарственного средства. Соединения являются лигандами A-рецептора и применимы при лечении неврологических и психических расстройств, в которые вовлечен A-рецептор.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61223604P | 2004-09-22 | 2004-09-22 | |
DKPA200401441 | 2004-09-22 | ||
PCT/DK2005/000591 WO2006032273A1 (en) | 2004-09-22 | 2005-09-20 | 2-acylaminothiazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200700707A1 true EA200700707A1 (ru) | 2007-08-31 |
Family
ID=35169521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200700707A EA200700707A1 (ru) | 2004-09-22 | 2005-09-20 | Производные 2-ациламинотиазола |
Country Status (8)
Country | Link |
---|---|
US (1) | US7910613B2 (ru) |
EP (1) | EP1794157B1 (ru) |
AU (1) | AU2005287729A1 (ru) |
CA (1) | CA2581105A1 (ru) |
EA (1) | EA200700707A1 (ru) |
MX (1) | MX2007003381A (ru) |
NO (1) | NO20072060L (ru) |
WO (1) | WO2006032273A1 (ru) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1700856E (pt) | 2003-12-26 | 2016-02-19 | Kyowa Hakko Kirin Co Ltd | Derivado de tiazole |
US7674912B2 (en) | 2005-04-25 | 2010-03-09 | H. Lundbeck A/S | Pro-drugs of N-thiazol-2-yl-benzamide derivatives |
US20100280023A1 (en) * | 2005-06-23 | 2010-11-04 | Kyowa Hakko Kogyo Co., Ltd. | Thiazole derivatives |
DK1921077T3 (en) | 2005-08-02 | 2017-10-23 | Kyowa Hakko Kirin Co Ltd | Means for treating and / or preventing sleep disorders |
TWI473614B (zh) | 2008-05-29 | 2015-02-21 | Kyowa Hakko Kirin Co Ltd | Anti-analgesic inhibitors |
EP2322223A4 (en) * | 2008-07-23 | 2012-08-22 | Kyowa Hakko Kirin Co Ltd | THERAPEUTIC AGENT AGAINST MIGRAINE |
TWI548411B (zh) | 2009-04-28 | 2016-09-11 | Kyowa Hakko Kirin Co Ltd | Exercise disorder treatment |
WO2018166855A1 (en) | 2017-03-16 | 2018-09-20 | Basf Se | Heterobicyclic substituted dihydroisoxazoles |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE855120C (de) | 1950-10-08 | 1953-01-05 | Schering Ag | Verfahren zur Herstellung von Aminosalicylsaeureamiden |
CA2020437A1 (en) | 1989-07-05 | 1991-01-06 | Yoshihide Fuse | Cinnamamide derivative |
JP2903339B2 (ja) | 1990-10-12 | 1999-06-07 | 大日精化工業株式会社 | 電子写真感光体 |
ATE254609T1 (de) | 1995-05-18 | 2003-12-15 | Zeria Pharm Co Ltd | Aminothiazolderivate, sie enthaltende arzneimittel und zwischenprodukte in der herstellung dieser verbindungen |
TW513418B (en) * | 1996-07-31 | 2002-12-11 | Otsuka Pharma Co Ltd | Thiazole derivatives, their production and use |
US6121301A (en) | 1996-10-24 | 2000-09-19 | Zeria Pharmaceutical Co., Ltd. | Substituted benzoylaminothiazole derivatives and drugs containing the same |
AU4506399A (en) * | 1998-06-05 | 1999-12-30 | Novartis Ag | Aryl pyridinyl thiazoles |
GB9823871D0 (en) | 1998-10-30 | 1998-12-23 | Pharmacia & Upjohn Spa | 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents |
ATE295831T1 (de) | 1999-03-10 | 2005-06-15 | Shionogi & Co | Medizinische zubereitungen mit (2.2.1) und (3.1.1)bicycloskelett die antagonisten für sowohl pgd 2? als auch txa 2? rezeptoren sind |
US7125875B2 (en) | 1999-04-15 | 2006-10-24 | Bristol-Myers Squibb Company | Cyclic protein tyrosine kinase inhibitors |
KR100710100B1 (ko) | 1999-04-15 | 2007-04-23 | 브리스톨-마이어스스퀴브컴파니 | 환형 단백질 티로신 키나제 억제제 |
FR2796643B1 (fr) * | 1999-07-22 | 2005-04-29 | Sod Conseils Rech Applic | Derives de 2-arylimino-2, 3-dihydrothiazoles, leurs procedes de preparation et leur utilisation therapeutique |
AU2001260627A1 (en) | 2000-06-02 | 2001-12-17 | Shionogi And Co., Ltd. | Drug composition antagonistic to both pgd2/txa2 receptors |
GB0028383D0 (en) * | 2000-11-21 | 2001-01-03 | Novartis Ag | Organic compounds |
GB0100624D0 (en) | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds VII |
CN1516696A (zh) | 2001-01-26 | 2004-07-28 | 盐野义制药株式会社 | 对血小板生成素受体具有激动作用的卤素化合物 |
US7429593B2 (en) | 2001-09-14 | 2008-09-30 | Shionogi & Co., Ltd. | Utilities of amide compounds |
US6624163B2 (en) | 2001-11-29 | 2003-09-23 | Hoffman-La Roche Inc. | Benzothiazole derivatives |
US6713499B2 (en) | 2001-12-12 | 2004-03-30 | Hoffman-La Roche Inc. | 7-Amino-benzothiazole derivatives |
WO2003057689A1 (en) | 2002-01-02 | 2003-07-17 | Fujisawa Pharmaceutical Co., Ltd. | Aminopyrimidine compounds, processes for their preparation and pharmaceutical compositions containing them |
US20040209930A1 (en) | 2002-10-02 | 2004-10-21 | Carboni Joan M. | Synergistic methods and compositions for treating cancer |
ATE490775T1 (de) | 2002-12-19 | 2010-12-15 | Schering Corp | Verwendung von a2a rezeptor-antagonisten zur behandlung des extrapyramidalen syndroms |
DE10348022A1 (de) | 2003-10-15 | 2005-05-25 | Imtm Gmbh | Neue Dipeptidylpeptidase IV-Inhibitoren zur funktionellen Beeinflussung unterschiedlicher Zellen und zur Behandlung immunologischer, entzündlicher, neuronaler und anderer Erkrankungen |
TW200524887A (en) | 2003-10-27 | 2005-08-01 | Lundbeck & Co As H | N-thiazol-2-yl-benzamide derivatives |
PT1700856E (pt) | 2003-12-26 | 2016-02-19 | Kyowa Hakko Kirin Co Ltd | Derivado de tiazole |
MX2007002584A (es) | 2004-09-02 | 2007-09-07 | Genentech Inc | Inhibidores de piridilo de senalizacion de hedgehog. |
US20080312435A1 (en) | 2004-11-15 | 2008-12-18 | Taisho Pharmaceutical Co., Ltd. | Imine Compound |
US7674912B2 (en) | 2005-04-25 | 2010-03-09 | H. Lundbeck A/S | Pro-drugs of N-thiazol-2-yl-benzamide derivatives |
DK1921077T3 (en) | 2005-08-02 | 2017-10-23 | Kyowa Hakko Kirin Co Ltd | Means for treating and / or preventing sleep disorders |
WO2007022415A2 (en) | 2005-08-18 | 2007-02-22 | Pharmacopeia, Inc. | Substituted 2-aminothiazoles for treating neurodegenerative diseases |
-
2005
- 2005-09-20 EA EA200700707A patent/EA200700707A1/ru unknown
- 2005-09-20 MX MX2007003381A patent/MX2007003381A/es active IP Right Grant
- 2005-09-20 WO PCT/DK2005/000591 patent/WO2006032273A1/en active Application Filing
- 2005-09-20 EP EP05784170.2A patent/EP1794157B1/en active Active
- 2005-09-20 CA CA002581105A patent/CA2581105A1/en not_active Abandoned
- 2005-09-20 AU AU2005287729A patent/AU2005287729A1/en not_active Abandoned
- 2005-09-20 US US11/663,054 patent/US7910613B2/en not_active Expired - Fee Related
-
2007
- 2007-04-23 NO NO20072060A patent/NO20072060L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US7910613B2 (en) | 2011-03-22 |
CA2581105A1 (en) | 2006-03-30 |
AU2005287729A1 (en) | 2006-03-30 |
EP1794157B1 (en) | 2014-02-26 |
US20090137642A1 (en) | 2009-05-28 |
WO2006032273A1 (en) | 2006-03-30 |
MX2007003381A (es) | 2007-04-27 |
NO20072060L (no) | 2007-04-23 |
EP1794157A1 (en) | 2007-06-13 |
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