SI1645558T1 - Piperazinilpirazini kot modulatorji serotonin 5-HT2C receptorja - Google Patents

Piperazinilpirazini kot modulatorji serotonin 5-HT2C receptorja

Info

Publication number
SI1645558T1
SI1645558T1 SI200331283T SI200331283T SI1645558T1 SI 1645558 T1 SI1645558 T1 SI 1645558T1 SI 200331283 T SI200331283 T SI 200331283T SI 200331283 T SI200331283 T SI 200331283T SI 1645558 T1 SI1645558 T1 SI 1645558T1
Authority
SI
Slovenia
Prior art keywords
serotonin
piperazinylpyrazines
receptor modulators
ht2c receptor
relates
Prior art date
Application number
SI200331283T
Other languages
English (en)
Inventor
Magnus Cernerud
Helena Lundstrom
Claes Lofstrom
Margit Pelcman
Tom Fleck
Alexander Paptchikhine
Emma Andersson
Alf Nygren
Original Assignee
Biovitrum Ab Publ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0201881A external-priority patent/SE0201881D0/xx
Priority claimed from SE0202041A external-priority patent/SE0202041D0/xx
Priority claimed from SE0202516A external-priority patent/SE0202516D0/xx
Application filed by Biovitrum Ab Publ filed Critical Biovitrum Ab Publ
Publication of SI1645558T1 publication Critical patent/SI1645558T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Luminescent Compositions (AREA)
SI200331283T 2002-06-19 2003-06-18 Piperazinilpirazini kot modulatorji serotonin 5-HT2C receptorja SI1645558T1 (sl)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
SE0201881A SE0201881D0 (sv) 2002-06-19 2002-06-19 Novel compounds, their use, and preparation
US39065602P 2002-06-21 2002-06-21
SE0202041A SE0202041D0 (sv) 2002-06-28 2002-06-28 Novel process
US40611902P 2002-08-26 2002-08-26
SE0202516A SE0202516D0 (sv) 2002-08-26 2002-08-26 Novel compounds, their use, and preparation
US41670102P 2002-10-07 2002-10-07
EP05023471A EP1645558B1 (en) 2002-06-19 2003-06-18 Piperazinylpyrazines as serotonin 5-HT2C receptor modulators

Publications (1)

Publication Number Publication Date
SI1645558T1 true SI1645558T1 (sl) 2008-10-31

Family

ID=30004077

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200331283T SI1645558T1 (sl) 2002-06-19 2003-06-18 Piperazinilpirazini kot modulatorji serotonin 5-HT2C receptorja
SI200330493T SI1529043T1 (sl) 2002-06-19 2003-06-18 Postopek za pripravo 2-metil piperazinskih derivatov

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200330493T SI1529043T1 (sl) 2002-06-19 2003-06-18 Postopek za pripravo 2-metil piperazinskih derivatov

Country Status (16)

Country Link
EP (2) EP1529043B1 (sl)
JP (4) JP4592417B2 (sl)
CN (1) CN100334082C (sl)
AT (2) ATE398119T1 (sl)
AU (1) AU2003237746B8 (sl)
CA (1) CA2485532C (sl)
CY (1) CY1106225T1 (sl)
DE (2) DE60307286T2 (sl)
DK (2) DK1529043T3 (sl)
ES (2) ES2270051T3 (sl)
HK (1) HK1080079B (sl)
NO (1) NO20050279D0 (sl)
NZ (1) NZ536663A (sl)
PT (2) PT1529043E (sl)
SI (2) SI1645558T1 (sl)
WO (1) WO2004000829A1 (sl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5173190B2 (ja) 2004-08-25 2013-03-27 武田薬品工業株式会社 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法
JP5528699B2 (ja) 2006-05-16 2014-06-25 武田薬品工業株式会社 縮合複素環化合物およびその用途
BRPI0818338A2 (pt) 2007-10-16 2015-04-22 Daiichi Sankyo Co Ltd Composto de pirimidil indolina
US20100266504A1 (en) 2007-11-15 2010-10-21 Takahiro Matsumoto Condensed pyridine derivative and use thereof
AU2010260847B2 (en) 2009-06-15 2016-11-24 Takeda Pharmaceutical Company Limited Pyrazinooxazepine derivatives
US20120253036A1 (en) 2009-12-11 2012-10-04 Yukinori Nagakura Agent for treating fibromyalgia
GB201304811D0 (en) * 2013-03-15 2013-05-01 Proximagen Ltd Novel treatment for hypertension
US20210052600A1 (en) 2017-12-27 2021-02-25 Takeda Pharmaceutical Company Limited Therapeutic agents for stress urinary incontinence and incotinence of feces

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06306075A (ja) * 1993-04-23 1994-11-01 Sanwa Kagaku Kenkyusho Co Ltd エトキシベンズアミド誘導体
IL146582A0 (en) * 1999-05-21 2002-07-25 Biovitrum Ab Novel compounds, their use and preparation
AR032318A1 (es) * 2000-04-13 2003-11-05 Pharmacia Corp Compuesto derivado halogenado del acido 2-amino-5,6 heptenoico; composicion farmaceutica que lo comprende y su uso en la fabricacion de un medicamento util como inhibidor de la oxido nitrico sintetasa
PL360982A1 (en) * 2000-11-20 2004-09-20 Biovitrum Ab Piperazinylpyrazines compounds as antagonists of serotonin 5-ht2 receptor

Also Published As

Publication number Publication date
EP1529043B1 (en) 2006-08-02
AU2003237746A1 (en) 2004-01-06
DE60321606D1 (de) 2008-07-24
DK1645558T3 (da) 2008-10-06
NO20050279D0 (no) 2005-01-18
JP5378241B2 (ja) 2013-12-25
JP2013116906A (ja) 2013-06-13
EP1529043A1 (en) 2005-05-11
NZ536663A (en) 2007-05-31
WO2004000829A1 (en) 2003-12-31
EP1645558B1 (en) 2008-06-11
ES2270051T3 (es) 2007-04-01
SI1529043T1 (sl) 2006-12-31
CA2485532A1 (en) 2003-12-31
HK1080079B (zh) 2008-03-14
PT1529043E (pt) 2006-12-29
CN100334082C (zh) 2007-08-29
PT1645558E (pt) 2008-07-30
DK1529043T3 (da) 2006-12-04
JP2010120949A (ja) 2010-06-03
AU2003237746B8 (en) 2010-01-28
CY1106225T1 (el) 2011-06-08
JP2013227336A (ja) 2013-11-07
CN1662523A (zh) 2005-08-31
CA2485532C (en) 2012-03-06
DE60307286D1 (de) 2006-09-14
JP2005537316A (ja) 2005-12-08
HK1080079A1 (en) 2006-04-21
JP4592417B2 (ja) 2010-12-01
DE60307286T2 (de) 2007-10-25
AU2003237746B2 (en) 2009-12-17
ES2307102T3 (es) 2008-11-16
ATE398119T1 (de) 2008-07-15
ATE334980T1 (de) 2006-08-15
EP1645558A1 (en) 2006-04-12

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