BRPI0818338A2 - Composto de pirimidil indolina - Google Patents

Composto de pirimidil indolina

Info

Publication number
BRPI0818338A2
BRPI0818338A2 BRPI0818338A BRPI0818338A2 BR PI0818338 A2 BRPI0818338 A2 BR PI0818338A2 BR PI0818338 A BRPI0818338 A BR PI0818338A BR PI0818338 A2 BRPI0818338 A2 BR PI0818338A2
Authority
BR
Brazil
Prior art keywords
pyrimidil
indoline
compound
pyrimidil compound
indoline pyrimidil
Prior art date
Application number
Other languages
English (en)
Inventor
Toshio Kaneko
Takeshi Shida
Koji Matsumoto
Kazumasa Aoki
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of BRPI0818338A2 publication Critical patent/BRPI0818338A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
BRPI0818338 2007-10-16 2008-10-15 Composto de pirimidil indolina BRPI0818338A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007268937 2007-10-16
PCT/JP2008/068607 WO2009051119A1 (ja) 2007-10-16 2008-10-15 ピリミジルインドリン化合物

Publications (1)

Publication Number Publication Date
BRPI0818338A2 true BRPI0818338A2 (pt) 2015-04-22

Family

ID=40567381

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0818338 BRPI0818338A2 (pt) 2007-10-16 2008-10-15 Composto de pirimidil indolina

Country Status (16)

Country Link
US (1) US8232287B2 (pt)
EP (1) EP2210886B1 (pt)
JP (1) JP5317354B2 (pt)
KR (1) KR101536021B1 (pt)
CN (1) CN101896481B (pt)
AU (1) AU2008312948C1 (pt)
BR (1) BRPI0818338A2 (pt)
CA (1) CA2710182C (pt)
IL (1) IL205057A0 (pt)
MX (1) MX2010004232A (pt)
MY (1) MY151295A (pt)
NZ (1) NZ585284A (pt)
RU (1) RU2464269C2 (pt)
TW (1) TWI421074B (pt)
WO (1) WO2009051119A1 (pt)
ZA (1) ZA201002552B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8410089B2 (en) * 2009-02-18 2013-04-02 Takeda Pharmaceutical Company Limited Fused heterocyclic ring compound
WO2010128414A1 (en) * 2009-05-08 2010-11-11 Pfizer Inc. Gpr 119 modulators
EP2427450A1 (en) * 2009-05-08 2012-03-14 Pfizer Inc. Gpr 119 modulators
JP2012530758A (ja) * 2009-06-24 2012-12-06 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規化合物、医薬組成物及びそれに関する方法
NZ596445A (en) 2009-06-24 2013-04-26 Boehringer Ingelheim Int New compounds, pharmaceutical composition and methods relating thereto
EP2462123B1 (en) * 2009-08-04 2013-10-02 Merck Sharp & Dohme Corp. 4,5,6-trisubstituted pyrimidine derivatives as factor ixa inhibitors
WO2011025006A1 (ja) * 2009-08-31 2011-03-03 日本ケミファ株式会社 Ｇｐｒ１１９作動薬
EP2504342A1 (en) * 2009-11-23 2012-10-03 Pfizer Inc. Imidazo-pyrazoles as gpr119 inhibitors
KR20120125302A (ko) 2010-01-20 2012-11-14 사노피 알킬-헤테로사이클 카르바메이트 유도체, 그의 제조법 및 그의 치료 용도
FR2955580A1 (fr) * 2010-01-28 2011-07-29 Sanofi Aventis Derives de carbamate d'alkyl-heterocycles, leur preparation et leur application en therapeutique
TW201204733A (en) 2010-06-25 2012-02-01 Kowa Co Novel condensed pyridine or condensed pyrimidine derivative, and medicinal agent comprising same
WO2012025811A1 (en) 2010-08-23 2012-03-01 Lupin Limited Indolylpyrimidines as modulators of gpr119
DK2625177T3 (en) 2010-10-08 2015-10-12 Cadila Healthcare Ltd New GPR 119 agonists
AU2011333472A1 (en) * 2010-11-26 2013-06-06 Lupin Limited Bicyclic GPR119 modulators
EP2567959B1 (en) 2011-09-12 2014-04-16 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
NZ627303A (en) 2012-01-18 2015-11-27 Daiichi Sankyo Co Ltd Substituted phenylazole derivative
JP6540505B2 (ja) * 2013-03-29 2019-07-10 国立大学法人 熊本大学 ２型糖尿病治療剤
MX2021007017A (es) * 2019-01-08 2021-07-21 Kyorin Seiyaku Kk Inhibidor de la 15-pgdh.

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW406075B (en) * 1994-12-13 2000-09-21 Upjohn Co Alkyl substituted piperidinyl and piperazinyl anti-AIDS compounds
US7101869B2 (en) 1999-11-30 2006-09-05 Pfizer Inc. 2,4-diaminopyrimidine compounds useful as immunosuppressants
AP2002002530A0 (en) * 1999-11-30 2002-06-30 Pfizer Prod Inc 2,4 diaminopyrimidine compounds useful as immunosuppressants.
EP1645558B1 (en) 2002-06-19 2008-06-11 Biovitrum AB (publ) Piperazinylpyrazines as serotonin 5-HT2C receptor modulators
US7078419B2 (en) * 2003-03-10 2006-07-18 Boehringer Ingelheim Pharmaceuticals, Inc. Cytokine inhibitors
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
UA86943C2 (ru) * 2003-07-11 2009-06-10 Арена Фармасьютикалз, Инк. Тризамещенные производные арилов и гетероарилов как модуляторы метаболизма и профилактика и лечение связанных с ними нарушений
FR2866884B1 (fr) * 2004-02-26 2007-08-31 Sanofi Synthelabo Derives d'aryl-et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application en therapeutique
ATE415397T1 (de) 2004-06-04 2008-12-15 Arena Pharm Inc Substituierte aryl- und heteroarylderivate als modulatoren des stoffwechsels und für die prophylaxe und behandlung von damit in zusammenhang stehenden erkrankungen
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
BRPI0613505A2 (pt) 2005-06-30 2011-01-11 Prosidion Ltd agonistas de gpcr
EP2043744A2 (en) * 2006-07-13 2009-04-08 SmithKline Beecham Corporation Chemical compounds

Also Published As

Publication number Publication date
KR20100071068A (ko) 2010-06-28
AU2008312948C1 (en) 2012-08-09
US20100292259A1 (en) 2010-11-18
KR101536021B1 (ko) 2015-07-10
TWI421074B (zh) 2014-01-01
AU2008312948A1 (en) 2009-04-23
EP2210886A4 (en) 2011-08-17
MY151295A (en) 2014-04-30
IL205057A0 (en) 2010-11-30
JPWO2009051119A1 (ja) 2011-03-03
WO2009051119A1 (ja) 2009-04-23
AU2008312948B2 (en) 2012-03-01
US8232287B2 (en) 2012-07-31
ZA201002552B (en) 2011-10-26
MX2010004232A (es) 2010-09-30
CA2710182A1 (en) 2009-04-23
CN101896481A (zh) 2010-11-24
RU2464269C2 (ru) 2012-10-20
JP5317354B2 (ja) 2013-10-16
RU2010119487A (ru) 2011-11-27
CA2710182C (en) 2012-08-14
TW200922588A (en) 2009-06-01
CN101896481B (zh) 2014-04-30
EP2210886B1 (en) 2015-09-23
EP2210886A1 (en) 2010-07-28
NZ585284A (en) 2011-03-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]