DK1527097T3 - Fremgangsmåde til rensning af preproinsulin - Google Patents

Fremgangsmåde til rensning af preproinsulin

Info

Publication number
DK1527097T3
DK1527097T3 DK03766211T DK03766211T DK1527097T3 DK 1527097 T3 DK1527097 T3 DK 1527097T3 DK 03766211 T DK03766211 T DK 03766211T DK 03766211 T DK03766211 T DK 03766211T DK 1527097 T3 DK1527097 T3 DK 1527097T3
Authority
DK
Denmark
Prior art keywords
preproinsulin
purifying
preproinsulins
chromatography
preparing
Prior art date
Application number
DK03766211T
Other languages
Danish (da)
English (en)
Inventor
Horst Thurow
Hans Blumenstock
Chantalle Havenith
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1527097T3 publication Critical patent/DK1527097T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DK03766211T 2002-08-01 2003-07-18 Fremgangsmåde til rensning af preproinsulin DK1527097T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10235168A DE10235168A1 (de) 2002-08-01 2002-08-01 Verfahren zur Reinigung von Preproinsulin
PCT/EP2003/007820 WO2004013176A1 (de) 2002-08-01 2003-07-18 Verfahren zur reinigung von preproinsulin

Publications (1)

Publication Number Publication Date
DK1527097T3 true DK1527097T3 (da) 2008-05-26

Family

ID=30128614

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03766211T DK1527097T3 (da) 2002-08-01 2003-07-18 Fremgangsmåde til rensning af preproinsulin

Country Status (16)

Country Link
US (2) US20050080000A1 (enExample)
EP (1) EP1527097B1 (enExample)
JP (1) JP4519646B2 (enExample)
AT (1) ATE384742T1 (enExample)
AU (1) AU2003254375B2 (enExample)
BR (1) BR0313131A (enExample)
CA (1) CA2493539C (enExample)
CY (1) CY1108046T1 (enExample)
DE (2) DE10235168A1 (enExample)
DK (1) DK1527097T3 (enExample)
ES (1) ES2297223T3 (enExample)
IL (1) IL166438A (enExample)
MX (1) MXPA05001042A (enExample)
PT (1) PT1527097E (enExample)
SI (1) SI1527097T1 (enExample)
WO (1) WO2004013176A1 (enExample)

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DK2498802T3 (en) 2009-11-13 2015-04-13 Sanofi Aventis Deutschland Pharmaceutical composition comprising a GLP-1 agonist, insulin and a methionine
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AU2011202239C1 (en) 2010-05-19 2017-03-16 Sanofi Long-acting formulations of insulins
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ES2606554T3 (es) 2010-08-30 2017-03-24 Sanofi-Aventis Deutschland Gmbh Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2
WO2012104339A1 (en) 2011-02-01 2012-08-09 Novo Nordisk A/S Purification of insulin
DE102011003944A1 (de) 2011-02-10 2012-08-16 Oxprotect Gmbh Detektion und Entfernung von missgefalteten Proteinen/Peptiden
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
CN102219851B (zh) * 2011-05-09 2012-05-30 甘李药业有限公司 甘精胰岛素结晶的制备方法
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
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PL2750699T3 (pl) 2011-08-29 2015-12-31 Sanofi Aventis Deutschland Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
HK1200318A1 (en) 2011-10-24 2015-08-07 曼金德公司 Methods and compositions for treating pain
EP2872205B1 (en) 2012-07-12 2017-02-08 MannKind Corporation Dry powder drug delivery systems
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US10421795B2 (en) * 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
MX369511B (es) 2013-04-03 2019-11-11 Sanofi Sa Tratamiento de la diabetes mellitus mediante formulaciones de insulinas de acción prolongada.
KR102465025B1 (ko) 2013-07-18 2022-11-09 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
RU2694063C2 (ru) * 2014-07-08 2019-07-09 Эмфастар Фармасьютикалз, Инк. Тонкодисперсный инсулин, тонкодисперсные аналоги инсулина и способы их промышленного получения
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
AU2015359376B2 (en) 2014-12-12 2021-09-09 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
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Also Published As

Publication number Publication date
JP4519646B2 (ja) 2010-08-04
WO2004013176A1 (de) 2004-02-12
AU2003254375B2 (en) 2009-01-08
BR0313131A (pt) 2005-07-05
DE10235168A1 (de) 2004-02-12
ATE384742T1 (de) 2008-02-15
US20060183666A1 (en) 2006-08-17
CA2493539A1 (en) 2004-02-12
EP1527097A1 (de) 2005-05-04
AU2003254375A1 (en) 2004-02-23
CY1108046T1 (el) 2013-09-04
IL166438A (en) 2010-11-30
US20050080000A1 (en) 2005-04-14
PT1527097E (pt) 2008-02-25
ES2297223T3 (es) 2008-05-01
MXPA05001042A (es) 2005-04-08
JP2006513978A (ja) 2006-04-27
DE50309087D1 (enExample) 2008-03-13
CA2493539C (en) 2012-01-31
EP1527097B1 (de) 2008-01-23
US7803763B2 (en) 2010-09-28
IL166438A0 (en) 2006-01-15
SI1527097T1 (sl) 2008-04-30

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