SI1527097T1 - Postopek za ciscenje preproinzulina - Google Patents

Postopek za ciscenje preproinzulina

Info

Publication number
SI1527097T1
SI1527097T1 SI200331119T SI200331119T SI1527097T1 SI 1527097 T1 SI1527097 T1 SI 1527097T1 SI 200331119 T SI200331119 T SI 200331119T SI 200331119 T SI200331119 T SI 200331119T SI 1527097 T1 SI1527097 T1 SI 1527097T1
Authority
SI
Slovenia
Prior art keywords
preproinsulin
purifying
preproinsulins
chromatography
preparing
Prior art date
Application number
SI200331119T
Other languages
English (en)
Slovenian (sl)
Inventor
Horst Thurow
Hans Blumenstock
Chantalle Havenith
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of SI1527097T1 publication Critical patent/SI1527097T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
SI200331119T 2002-08-01 2003-07-18 Postopek za ciscenje preproinzulina SI1527097T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10235168A DE10235168A1 (de) 2002-08-01 2002-08-01 Verfahren zur Reinigung von Preproinsulin
PCT/EP2003/007820 WO2004013176A1 (de) 2002-08-01 2003-07-18 Verfahren zur reinigung von preproinsulin
EP03766211A EP1527097B1 (de) 2002-08-01 2003-07-18 Verfahren zur reinigung von preproinsulin

Publications (1)

Publication Number Publication Date
SI1527097T1 true SI1527097T1 (sl) 2008-04-30

Family

ID=30128614

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200331119T SI1527097T1 (sl) 2002-08-01 2003-07-18 Postopek za ciscenje preproinzulina

Country Status (16)

Country Link
US (2) US20050080000A1 (enExample)
EP (1) EP1527097B1 (enExample)
JP (1) JP4519646B2 (enExample)
AT (1) ATE384742T1 (enExample)
AU (1) AU2003254375B2 (enExample)
BR (1) BR0313131A (enExample)
CA (1) CA2493539C (enExample)
CY (1) CY1108046T1 (enExample)
DE (2) DE10235168A1 (enExample)
DK (1) DK1527097T3 (enExample)
ES (1) ES2297223T3 (enExample)
IL (1) IL166438A (enExample)
MX (1) MXPA05001042A (enExample)
PT (1) PT1527097E (enExample)
SI (1) SI1527097T1 (enExample)
WO (1) WO2004013176A1 (enExample)

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PL2464655T3 (pl) * 2009-08-11 2017-08-31 Biocon Limited Procesy chromatograficzne
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
DK2498802T3 (en) 2009-11-13 2015-04-13 Sanofi Aventis Deutschland Pharmaceutical composition comprising a GLP-1 agonist, insulin and a methionine
KR101337322B1 (ko) 2009-11-13 2013-12-06 사노피-아벤티스 도이칠란트 게엠베하 Ｇｌｐ-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
AU2011202239C1 (en) 2010-05-19 2017-03-16 Sanofi Long-acting formulations of insulins
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ES2606554T3 (es) 2010-08-30 2017-03-24 Sanofi-Aventis Deutschland Gmbh Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2
WO2012104339A1 (en) 2011-02-01 2012-08-09 Novo Nordisk A/S Purification of insulin
DE102011003944A1 (de) 2011-02-10 2012-08-16 Oxprotect Gmbh Detektion und Entfernung von missgefalteten Proteinen/Peptiden
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
CN102219851B (zh) * 2011-05-09 2012-05-30 甘李药业有限公司 甘精胰岛素结晶的制备方法
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
PL2750699T3 (pl) 2011-08-29 2015-12-31 Sanofi Aventis Deutschland Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
HK1200318A1 (en) 2011-10-24 2015-08-07 曼金德公司 Methods and compositions for treating pain
EP2872205B1 (en) 2012-07-12 2017-02-08 MannKind Corporation Dry powder drug delivery systems
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US10421795B2 (en) * 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
MX369511B (es) 2013-04-03 2019-11-11 Sanofi Sa Tratamiento de la diabetes mellitus mediante formulaciones de insulinas de acción prolongada.
KR102465025B1 (ko) 2013-07-18 2022-11-09 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
RU2694063C2 (ru) * 2014-07-08 2019-07-09 Эмфастар Фармасьютикалз, Инк. Тонкодисперсный инсулин, тонкодисперсные аналоги инсулина и способы их промышленного получения
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
AU2015359376B2 (en) 2014-12-12 2021-09-09 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
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Also Published As

Publication number Publication date
JP4519646B2 (ja) 2010-08-04
WO2004013176A1 (de) 2004-02-12
AU2003254375B2 (en) 2009-01-08
BR0313131A (pt) 2005-07-05
DE10235168A1 (de) 2004-02-12
ATE384742T1 (de) 2008-02-15
US20060183666A1 (en) 2006-08-17
CA2493539A1 (en) 2004-02-12
EP1527097A1 (de) 2005-05-04
AU2003254375A1 (en) 2004-02-23
CY1108046T1 (el) 2013-09-04
IL166438A (en) 2010-11-30
US20050080000A1 (en) 2005-04-14
PT1527097E (pt) 2008-02-25
ES2297223T3 (es) 2008-05-01
MXPA05001042A (es) 2005-04-08
DK1527097T3 (da) 2008-05-26
JP2006513978A (ja) 2006-04-27
DE50309087D1 (enExample) 2008-03-13
CA2493539C (en) 2012-01-31
EP1527097B1 (de) 2008-01-23
US7803763B2 (en) 2010-09-28
IL166438A0 (en) 2006-01-15

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