DK1753778T3 - Fremgangsmåde til rensning af erythropoietin - Google Patents

Fremgangsmåde til rensning af erythropoietin

Info

Publication number
DK1753778T3
DK1753778T3 DK05748375T DK05748375T DK1753778T3 DK 1753778 T3 DK1753778 T3 DK 1753778T3 DK 05748375 T DK05748375 T DK 05748375T DK 05748375 T DK05748375 T DK 05748375T DK 1753778 T3 DK1753778 T3 DK 1753778T3
Authority
DK
Denmark
Prior art keywords
chromatography
anion exchange
relates
hydrophobic interaction
purification steps
Prior art date
Application number
DK05748375T
Other languages
English (en)
Inventor
Christof Schumann
Michael Mack
Jan-Ole Hesse
Original Assignee
Bioceuticals Arzneimittel Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioceuticals Arzneimittel Ag filed Critical Bioceuticals Arzneimittel Ag
Application granted granted Critical
Publication of DK1753778T3 publication Critical patent/DK1753778T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK05748375T 2004-06-08 2005-06-07 Fremgangsmåde til rensning af erythropoietin DK1753778T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004027816A DE102004027816A1 (de) 2004-06-08 2004-06-08 Verfahren zur Reinigung von Erythropoietin
PCT/EP2005/006099 WO2005121173A1 (de) 2004-06-08 2005-06-07 Verfahren zur reinigung von erythropoietin

Publications (1)

Publication Number Publication Date
DK1753778T3 true DK1753778T3 (da) 2009-08-17

Family

ID=34969642

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05748375T DK1753778T3 (da) 2004-06-08 2005-06-07 Fremgangsmåde til rensning af erythropoietin

Country Status (13)

Country Link
US (1) US7619073B2 (da)
EP (1) EP1753778B9 (da)
AT (1) ATE428728T1 (da)
CA (1) CA2569465C (da)
CY (1) CY1109251T1 (da)
DE (2) DE102004027816A1 (da)
DK (1) DK1753778T3 (da)
ES (1) ES2325771T3 (da)
PL (1) PL1753778T3 (da)
PT (1) PT1753778E (da)
RS (1) RS50960B (da)
SI (1) SI1753778T1 (da)
WO (1) WO2005121173A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4155385A1 (en) † 2005-12-08 2023-03-29 Amgen Inc. Improved production of glycoproteins using manganese
EP2287174B8 (en) 2008-01-18 2016-12-07 Bio-Rad Laboratories, Inc. Enhanced purification of antibody fragments by apatite chromatography
DE102008002209A1 (de) 2008-06-04 2009-12-10 Evonik Degussa Gmbh Verfahren zur Aufreinigung von Erythropoietin
DE102008002210A1 (de) * 2008-06-04 2009-12-10 Evonik Degussa Gmbh Verfahren zur fermentativen Herstellung von Erythropoietin
WO2010034442A1 (en) * 2008-09-23 2010-04-01 F. Hoffmann-La Roche Ag Purification of erythropoietin
DE102008054716A1 (de) 2008-12-16 2010-06-17 Evonik Degussa Gmbh Inprozesskontrolle in einem Verfahren zur Herstellung von EPO
CN102648286A (zh) * 2009-10-16 2012-08-22 默沙东公司 在巴斯德毕赤氏酵母中生产缺乏与针对宿主细胞抗原的抗体的可检测交叉结合活性的蛋白质的方法
LT3037104T (lt) 2009-10-20 2020-09-10 Abbvie Inc. Anti-il-13 antikūnų izoliavimas ir gryninimas, naudojant afininę baltymo a chromatografiją
EP2444495A1 (en) * 2010-10-20 2012-04-25 Algenics Secretion of recombinant polypeptides in the extracellular medium of diatoms
CN102127164B (zh) 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 一种从水稻种子中提取重组人血清白蛋白的方法
CN102532254B (zh) * 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
KR101443257B1 (ko) 2011-10-18 2014-09-19 주식회사 종근당 낮은 등전점을 갖는 에리스로포이에틴 유사체의 정제방법
CN103880947B (zh) 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 一种分离纯化高纯度重组人血清白蛋白的层析方法
EP4400507A2 (en) * 2015-09-08 2024-07-17 Waters Technologies Corporation Multidimensional chromatography method for analysis of antibody-drug conjugates
EP3153522A1 (en) * 2015-10-09 2017-04-12 Hetero Drugs Limited Process for the purification of erythropoietin and darbepoetin alfa
JP6906497B2 (ja) 2016-03-09 2021-07-21 Ｊｃｒファーマ株式会社 変異型ヒトエリスロポエチンの製造方法
DK3613486T3 (da) * 2018-08-24 2021-01-04 Uga Biopharma Gmbh Metode og anlæg til rengøring af epo og/eller et epo-derivat

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3045996A1 (de) * 1980-12-05 1982-07-08 Medic Eschmann Handelsgesellschaft für medizinische Instrumente mbH, 2000 Hamburg Elektro-chirurgiegeraet
IL79176A (en) * 1985-06-20 1992-06-21 Kirin Amgen Inc Process for the recovery of erythropoietin from a fluid
US4954437A (en) * 1986-09-15 1990-09-04 Integrated Genetics, Inc. Cell encoding recombinant human erythropoietin
IL118201A (en) * 1995-05-11 2004-12-15 Roche Diagnostics Gmbh Preparation comprising a protein with human erythropoietin activity which is free of serum and non-recombinant mammalian protein and process for the preparation thereof
US5744587A (en) * 1995-06-07 1998-04-28 Zymogenetics, Inc. Method for purifying thrombopoietin
WO1999028346A1 (de) 1997-12-03 1999-06-10 Roche Diagnostics Gmbh Erythropoietin mit hoher spezifischer aktivität
BR9917606A (pt) * 1998-11-06 2002-12-31 Bio Sidus S A Procedimento para a purificação de eritropoetina humana recombinante a partir de sobrenadantes de cultivo de células e eritropoetina humana recombinante obtida com tal procedimento
US20060099674A1 (en) 2001-11-28 2006-05-11 Peter Alliger Chromatographic purification of recombinant human erythropoietin
DE60220451T2 (de) 2002-03-26 2008-01-24 Lek Pharmaceutical And Chemical Co. D.D. Verfahren für die herstellung eines gewünschten profils von erythropoietin glyko-isoformen
PT1428878E (pt) * 2002-12-13 2008-11-18 Bioceuticals Arzneimittel Ag Processo para a produção e purificação de eritropoietina

Also Published As

Publication number Publication date
PT1753778E (pt) 2009-07-16
CA2569465C (en) 2011-12-06
SI1753778T1 (sl) 2009-10-31
US7619073B2 (en) 2009-11-17
RS50960B (sr) 2010-10-31
CY1109251T1 (el) 2014-07-02
CA2569465A1 (en) 2005-12-22
PL1753778T3 (pl) 2009-10-30
ES2325771T3 (es) 2009-09-16
EP1753778B1 (de) 2009-04-15
EP1753778A1 (de) 2007-02-21
US20070293420A1 (en) 2007-12-20
WO2005121173A1 (de) 2005-12-22
DE502005007091D1 (de) 2009-05-28
ATE428728T1 (de) 2009-05-15
EP1753778B9 (de) 2010-02-24
DE102004027816A1 (de) 2006-01-05

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