DK1523486T3 - Tetracykliske arylsulfonylindoler med serotoninreceptor-affinitet - Google Patents
Tetracykliske arylsulfonylindoler med serotoninreceptor-affinitetInfo
- Publication number
- DK1523486T3 DK1523486T3 DK03760857T DK03760857T DK1523486T3 DK 1523486 T3 DK1523486 T3 DK 1523486T3 DK 03760857 T DK03760857 T DK 03760857T DK 03760857 T DK03760857 T DK 03760857T DK 1523486 T3 DK1523486 T3 DK 1523486T3
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutically acceptable
- compound
- serotonin receptor
- receptor affinity
- indoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN478CH2002 | 2002-06-21 | ||
| PCT/IN2003/000222 WO2004000849A2 (fr) | 2002-06-21 | 2003-06-19 | Nouveaux indoles tetracycliques arylsulfonyle ayant une affinite du recepteur de la serotonine et utiles comme agents therapeutiques, leur procede de preparation et compositions pharmaceutiques les contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1523486T3 true DK1523486T3 (da) | 2008-03-03 |
Family
ID=29798513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03760857T DK1523486T3 (da) | 2002-06-21 | 2003-06-19 | Tetracykliske arylsulfonylindoler med serotoninreceptor-affinitet |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7649097B2 (fr) |
| EP (1) | EP1523486B1 (fr) |
| JP (1) | JP4473120B2 (fr) |
| CN (1) | CN100378108C (fr) |
| AT (1) | ATE377603T1 (fr) |
| AU (1) | AU2003249582B2 (fr) |
| BR (1) | BR0312176A (fr) |
| CA (1) | CA2490254C (fr) |
| DE (1) | DE60317333T2 (fr) |
| DK (1) | DK1523486T3 (fr) |
| ES (1) | ES2297216T3 (fr) |
| HK (1) | HK1074843A1 (fr) |
| MX (1) | MXPA04012832A (fr) |
| NZ (1) | NZ537770A (fr) |
| RU (1) | RU2340619C2 (fr) |
| WO (1) | WO2004000849A2 (fr) |
| ZA (1) | ZA200409886B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100776118B1 (ko) * | 2002-11-28 | 2007-11-15 | 수벤 라이프 사이언시스 리미티드 | 엔-아릴술포닐-3-아미노알콕시인돌 |
| JP4571507B2 (ja) * | 2002-12-18 | 2010-10-27 | スベン ライフ サイエンシズ リミティド | セロトニン受容体親和性を有する四環系３−置換インドール |
| CA2552106C (fr) * | 2004-01-02 | 2011-10-11 | Suven Life Sciences Limited | Nouveaux indeno[2,1a]indenes et isoindol[2,1-a]indoles |
| US7786119B2 (en) * | 2004-04-01 | 2010-08-31 | Cardiome Pharma Corp. | Drug conjugates of ion channel modulating compounds |
| EP1856132B1 (fr) * | 2005-03-08 | 2009-04-01 | Suven Life Sciences Limited | Procede pour preparer des benzothiazinoindoles substitues |
| MX2022007994A (es) | 2019-12-26 | 2022-09-23 | Gilgamesh Pharmaceuticals Inc | Derivados de arilciclohexilamina y su uso en el tratamiento de trastornos psiquiátricos. |
| CA3172046A1 (fr) | 2020-02-18 | 2021-08-26 | Gilgamesh Pharmaceuticals, Inc. | Tryptamines specifiques destinees a etre utilisees dans le traitement de troubles de l'humeur |
| KR20240096817A (ko) | 2020-05-19 | 2024-06-26 | 사이빈 아이알엘 리미티드 | 중수소화된 트립타민 유도체 및 사용 방법 |
| AU2021289147A1 (en) | 2020-06-12 | 2023-02-02 | Beckley Psytech Limited | Composition comprising a benzoate salt of 5-methoxy-N,N-dimethyltryptamine |
| GB202212116D0 (en) | 2022-08-19 | 2022-10-05 | Beckley Psytech Ltd | Pharmaceutically acceptable salts and Compositions thereof |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3481953A (en) * | 1967-12-18 | 1969-12-02 | American Home Prod | 1-arylsulfonyl-3-(2-substituted ethyl) indoles |
| ZA795239B (en) | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
| BE889931A (fr) * | 1980-08-12 | 1982-02-11 | Glaxo Group Ltd | Derives indoliques, leur preparation et leurs applications en tant que medicaments |
| GB8600397D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| GB8719167D0 (en) | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
| GB8724912D0 (en) | 1987-10-23 | 1987-11-25 | Wellcome Found | Indole derivatives |
| GB8819024D0 (en) | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
| IL96891A0 (en) | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
| CA2042295A1 (fr) | 1990-05-15 | 1991-11-16 | Jacques Chauveau | Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant |
| NZ238424A (en) | 1990-06-07 | 1993-12-23 | Wellcome Found | 3,5-substituted indole derivatives; medicaments and preparatory processes. |
| CZ283018B6 (cs) | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
| GB9113802D0 (en) | 1991-06-26 | 1991-08-14 | Smithkline Beecham Plc | Medicaments |
| GB9210400D0 (en) | 1992-05-15 | 1992-07-01 | Merck Sharp & Dohme | Therapeutic agents |
| KR940007001A (ko) | 1992-09-16 | 1994-04-26 | 최승주 | 새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제 |
| JP2000026471A (ja) | 1998-07-10 | 2000-01-25 | Nippon Soda Co Ltd | １１−ホルミル−インドロ［１，２−ｂ］［１，２］ベンズイソチアゾールおよび農園芸用殺菌剤 |
| GB9820113D0 (en) * | 1998-09-15 | 1998-11-11 | Merck Sharp & Dohme | Therapeutic agents |
| DE69930308T2 (de) * | 1998-12-11 | 2006-11-30 | Virginia Commonwealth University | Selektive 5-ht 6-rezeptor-liganden |
| ES2566056T3 (es) | 2001-03-29 | 2016-04-08 | Eli Lilly And Company | N-(2-ariletil)bencilaminas como antagonistas del receptor 5-HT6 |
-
2003
- 2003-06-19 AU AU2003249582A patent/AU2003249582B2/en not_active Ceased
- 2003-06-19 CN CNB038146029A patent/CN100378108C/zh not_active Expired - Fee Related
- 2003-06-19 CA CA2490254A patent/CA2490254C/fr not_active Expired - Fee Related
- 2003-06-19 DE DE60317333T patent/DE60317333T2/de not_active Expired - Lifetime
- 2003-06-19 JP JP2004515418A patent/JP4473120B2/ja not_active Expired - Fee Related
- 2003-06-19 MX MXPA04012832A patent/MXPA04012832A/es active IP Right Grant
- 2003-06-19 RU RU2005101344/04A patent/RU2340619C2/ru not_active IP Right Cessation
- 2003-06-19 EP EP03760857A patent/EP1523486B1/fr not_active Expired - Lifetime
- 2003-06-19 WO PCT/IN2003/000222 patent/WO2004000849A2/fr active IP Right Grant
- 2003-06-19 US US10/519,219 patent/US7649097B2/en not_active Expired - Fee Related
- 2003-06-19 DK DK03760857T patent/DK1523486T3/da active
- 2003-06-19 ES ES03760857T patent/ES2297216T3/es not_active Expired - Lifetime
- 2003-06-19 AT AT03760857T patent/ATE377603T1/de active
- 2003-06-19 BR BR0312176-3A patent/BR0312176A/pt not_active IP Right Cessation
- 2003-06-19 NZ NZ537770A patent/NZ537770A/en not_active IP Right Cessation
-
2004
- 2004-12-07 ZA ZA200409886A patent/ZA200409886B/en unknown
-
2005
- 2005-10-06 HK HK05108865A patent/HK1074843A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BR0312176A (pt) | 2005-04-05 |
| DE60317333T2 (de) | 2008-08-28 |
| ZA200409886B (en) | 2006-07-26 |
| US20050203154A1 (en) | 2005-09-15 |
| JP4473120B2 (ja) | 2010-06-02 |
| CA2490254C (fr) | 2011-11-01 |
| HK1074843A1 (en) | 2005-11-25 |
| CA2490254A1 (fr) | 2003-12-31 |
| MXPA04012832A (es) | 2005-05-27 |
| ATE377603T1 (de) | 2007-11-15 |
| US7649097B2 (en) | 2010-01-19 |
| DE60317333D1 (de) | 2007-12-20 |
| AU2003249582B2 (en) | 2006-08-03 |
| CN1662544A (zh) | 2005-08-31 |
| JP2005535621A (ja) | 2005-11-24 |
| AU2003249582A1 (en) | 2004-01-06 |
| WO2004000849A3 (fr) | 2004-03-25 |
| EP1523486B1 (fr) | 2007-11-07 |
| RU2340619C2 (ru) | 2008-12-10 |
| ES2297216T3 (es) | 2008-05-01 |
| WO2004000849A2 (fr) | 2003-12-31 |
| CN100378108C (zh) | 2008-04-02 |
| NZ537770A (en) | 2007-03-30 |
| EP1523486A2 (fr) | 2005-04-20 |
| RU2005101344A (ru) | 2005-08-20 |
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