DK1492517T3 - Hotmelt-TTS til administration af rotigotin - Google Patents
Hotmelt-TTS til administration af rotigotinInfo
- Publication number
- DK1492517T3 DK1492517T3 DK03750403T DK03750403T DK1492517T3 DK 1492517 T3 DK1492517 T3 DK 1492517T3 DK 03750403 T DK03750403 T DK 03750403T DK 03750403 T DK03750403 T DK 03750403T DK 1492517 T3 DK1492517 T3 DK 1492517T3
- Authority
- DK
- Denmark
- Prior art keywords
- tts
- rotigotine
- administration
- matrix
- hot melt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- External Artificial Organs (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10234673A DE10234673B4 (de) | 2002-07-30 | 2002-07-30 | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1492517T3 true DK1492517T3 (da) | 2006-08-28 |
Family
ID=30469194
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03750403T DK1492517T3 (da) | 2002-07-30 | 2003-07-29 | Hotmelt-TTS til administration af rotigotin |
Country Status (22)
Country | Link |
---|---|
US (1) | US9186335B2 (da) |
EP (2) | EP1492517B1 (da) |
JP (1) | JP4514608B2 (da) |
KR (1) | KR101041512B1 (da) |
CN (1) | CN100574755C (da) |
AT (1) | ATE324875T1 (da) |
AU (1) | AU2003269859B2 (da) |
BR (1) | BR0311437A (da) |
CA (1) | CA2494361C (da) |
CY (1) | CY1105138T1 (da) |
DE (2) | DE10234673B4 (da) |
DK (1) | DK1492517T3 (da) |
ES (1) | ES2263999T3 (da) |
HK (1) | HK1081436A1 (da) |
IL (1) | IL166070A0 (da) |
MX (1) | MXPA04012150A (da) |
NO (1) | NO20050835L (da) |
PL (1) | PL221308B1 (da) |
PT (1) | PT1492517E (da) |
RU (1) | RU2304434C2 (da) |
WO (1) | WO2004012721A2 (da) |
ZA (1) | ZA200500457B (da) |
Families Citing this family (55)
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DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
DE10041479A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
US8173155B2 (en) * | 2004-06-01 | 2012-05-08 | Hisamitsu Pharmaceutical Co., Inc. | Adhesive patch |
JP4986411B2 (ja) * | 2004-06-01 | 2012-07-25 | 久光製薬株式会社 | 貼付剤 |
EP1796610A4 (en) * | 2004-09-29 | 2012-12-05 | Schwarz Pharma Inc | TRANSDERMAL THERAPEUTIC SYSTEM FOR PARKINSON DISEASE |
DE102006026578B4 (de) | 2006-06-08 | 2009-01-08 | Lts Lohmann Therapie-Systeme Ag | Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung |
TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
DE102006059462A1 (de) * | 2006-12-14 | 2008-06-19 | Henkel Kgaa | Hot melt für Mikrowellen-Erwärmung |
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WO2008146284A2 (en) | 2007-05-30 | 2008-12-04 | Chemagis Ltd. | Crystalline rotigotine base and preparation process therefor |
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CN101970422B (zh) * | 2007-11-28 | 2014-10-22 | Ucb制药有限公司 | 罗替高汀的多晶型物 |
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DE102008060203A1 (de) | 2008-12-07 | 2010-06-10 | Dietrich Wilhelm Schacht | Wirkstoffstabilisierende flächenförmige Vorrichtung |
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DE102009052972A1 (de) | 2009-11-12 | 2011-09-15 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur Verhinderung der Kristallisation von Arzneistoffen in einem Polymerfilm |
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WO2013075823A1 (en) | 2011-11-22 | 2013-05-30 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermal therapeutic system comprising rotigotine and crystallization inhibitor |
DE102011119043A1 (de) | 2011-11-22 | 2013-05-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TDS) mit Rotigotin |
DE102012013421A1 (de) | 2012-07-03 | 2014-01-09 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TTS) mit Rotigotin |
DE102012013439A1 (de) | 2012-07-03 | 2014-01-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor |
DE102011090178A1 (de) | 2011-12-30 | 2013-07-04 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System mit geringer Neigung zur Spontankristallisation |
JP6180520B2 (ja) * | 2012-07-05 | 2017-08-16 | エスケー ケミカルス カンパニー リミテッド | ロチゴチンを含有した経皮吸収製剤(Transdermalcompositioncomprisingrotigotine) |
KR101558043B1 (ko) * | 2012-07-06 | 2015-10-07 | 에스케이케미칼주식회사 | 로티고틴 함유 경피흡수제제 |
TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片 |
WO2014193190A1 (ko) * | 2013-05-30 | 2014-12-04 | 에스케이케미칼 (주) | 로티고틴과 지방산 및 스티렌 점착제를 함유한 경피치료시스템 |
WO2014198422A1 (de) * | 2013-06-14 | 2014-12-18 | Tesa Labtec Gmbh | Transdermales therapiesystem (tts) mit rotigotin |
WO2014198423A1 (de) * | 2013-06-14 | 2014-12-18 | Tesa Labtec Gmbh | Dreischichtiges transdermales therapiesystem (tts) |
EP3010545A2 (en) * | 2013-06-20 | 2016-04-27 | Mylan Technologies, Inc. | Storage stable transdermal patch of rotigotine |
CA2916183C (en) | 2013-07-03 | 2022-03-29 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system with electronic component |
EP3145503A1 (en) | 2014-05-20 | 2017-03-29 | LTS Lohmann Therapie-Systeme AG | Method for adjusting the release of active agent in a transdermal delivery system |
WO2015177204A1 (en) | 2014-05-20 | 2015-11-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system containing rotigotine |
CA2948221C (en) | 2014-05-20 | 2022-11-22 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
KR102364378B1 (ko) | 2014-05-21 | 2022-02-16 | 에스케이케미칼 주식회사 | 안정성을 향상시킨 로티고틴 함유 경피흡수제제 |
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2002
- 2002-07-30 DE DE10234673A patent/DE10234673B4/de not_active Expired - Fee Related
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2003
- 2003-07-29 CA CA2494361A patent/CA2494361C/en not_active Expired - Fee Related
- 2003-07-29 AT AT03750403T patent/ATE324875T1/de active
- 2003-07-29 AU AU2003269859A patent/AU2003269859B2/en not_active Ceased
- 2003-07-29 PL PL374852A patent/PL221308B1/pl unknown
- 2003-07-29 KR KR1020057001416A patent/KR101041512B1/ko not_active IP Right Cessation
- 2003-07-29 US US10/523,908 patent/US9186335B2/en not_active Expired - Fee Related
- 2003-07-29 EP EP03750403A patent/EP1492517B1/de not_active Expired - Lifetime
- 2003-07-29 EP EP06005770A patent/EP1669063A1/de not_active Withdrawn
- 2003-07-29 ES ES03750403T patent/ES2263999T3/es not_active Expired - Lifetime
- 2003-07-29 JP JP2004525355A patent/JP4514608B2/ja not_active Expired - Fee Related
- 2003-07-29 IL IL16607003A patent/IL166070A0/xx unknown
- 2003-07-29 RU RU2005105684/15A patent/RU2304434C2/ru active
- 2003-07-29 PT PT03750403T patent/PT1492517E/pt unknown
- 2003-07-29 WO PCT/EP2003/008348 patent/WO2004012721A2/de active IP Right Grant
- 2003-07-29 MX MXPA04012150A patent/MXPA04012150A/es active IP Right Grant
- 2003-07-29 DK DK03750403T patent/DK1492517T3/da active
- 2003-07-29 CN CN03818378A patent/CN100574755C/zh not_active Expired - Fee Related
- 2003-07-29 DE DE50303201T patent/DE50303201D1/de not_active Expired - Lifetime
- 2003-07-29 BR BR0311437-6A patent/BR0311437A/pt not_active Application Discontinuation
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- 2005-01-18 ZA ZA2005/00457A patent/ZA200500457B/en unknown
- 2005-02-16 NO NO20050835A patent/NO20050835L/no not_active Application Discontinuation
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- 2006-02-06 HK HK06101569.3A patent/HK1081436A1/xx not_active IP Right Cessation
- 2006-07-28 CY CY20061101048T patent/CY1105138T1/el unknown
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