DK148960C - Analogifremgangsmaade til fremstilling af n-(4-piperidinyl)-n-phenyl-carbamoyl-derivater - Google Patents

Analogifremgangsmaade til fremstilling af n-(4-piperidinyl)-n-phenyl-carbamoyl-derivater

Info

Publication number
DK148960C
DK148960C DK110376A DK110376A DK148960C DK 148960 C DK148960 C DK 148960C DK 110376 A DK110376 A DK 110376A DK 110376 A DK110376 A DK 110376A DK 148960 C DK148960 C DK 148960C
Authority
DK
Denmark
Prior art keywords
piperidinyl
phenyl
preparing
analogy procedure
carbamoyl derivatives
Prior art date
Application number
DK110376A
Other languages
Danish (da)
English (en)
Other versions
DK110376A (da
DK148960B (da
Inventor
Paul Adriaan Jan Janssen
Georges Henri Paul Van Daele
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of DK110376A publication Critical patent/DK110376A/da
Publication of DK148960B publication Critical patent/DK148960B/da
Application granted granted Critical
Publication of DK148960C publication Critical patent/DK148960C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK110376A 1975-03-14 1976-03-12 Analogifremgangsmaade til fremstilling af n-(4-piperidinyl)-n-phenyl-carbamoyl-derivater DK148960C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US55851175A 1975-03-14 1975-03-14
US55851175 1975-03-14
US64868576 1976-01-13
US05/648,685 US3998834A (en) 1975-03-14 1976-01-13 N-(4-piperidinyl)-n-phenylamides and -carbamates

Publications (3)

Publication Number Publication Date
DK110376A DK110376A (da) 1976-09-15
DK148960B DK148960B (da) 1985-12-02
DK148960C true DK148960C (da) 1986-06-23

Family

ID=27071767

Family Applications (1)

Application Number Title Priority Date Filing Date
DK110376A DK148960C (da) 1975-03-14 1976-03-12 Analogifremgangsmaade til fremstilling af n-(4-piperidinyl)-n-phenyl-carbamoyl-derivater

Country Status (28)

Country Link
US (1) US3998834A (pt)
JP (1) JPS5946217B2 (pt)
AT (1) AT359493B (pt)
AU (1) AU503632B2 (pt)
BG (1) BG28259A3 (pt)
CA (1) CA1080232A (pt)
CH (1) CH629486A5 (pt)
CZ (1) CZ278060B6 (pt)
DE (1) DE2610228A1 (pt)
DK (1) DK148960C (pt)
ES (1) ES446034A1 (pt)
FI (1) FI61481C (pt)
FR (1) FR2303546A1 (pt)
GB (1) GB1538938A (pt)
HU (1) HU172963B (pt)
IE (1) IE42512B1 (pt)
IL (1) IL49204A (pt)
IT (1) IT1057988B (pt)
LU (1) LU74511A1 (pt)
NL (1) NL185279C (pt)
NO (1) NO146162C (pt)
NZ (1) NZ180096A (pt)
PH (1) PH12746A (pt)
PL (1) PL102474B1 (pt)
PT (1) PT64898B (pt)
SE (1) SE426486B (pt)
SU (1) SU1227109A3 (pt)
YU (1) YU39960B (pt)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179569A (en) * 1975-03-14 1979-12-18 Janssen Pharmaceutica N.V. N-(4-piperidinyl)-N-phenylamides
US4208418A (en) * 1975-09-23 1980-06-17 Janssen Pharmaceutica N.V. N-Aryl-N-(1-alkyl-4-piperidinyl)arylacetamides
US4225606A (en) * 1975-09-23 1980-09-30 Janssen Pharmaceutica N.V. N-Aryl-N-(1-L-4-piperidinyl)arylacetamides
FR2389622B1 (pt) * 1977-05-05 1982-05-21 Janssen Pharmaceutica Nv
US4167574A (en) * 1978-03-13 1979-09-11 Janssen Pharmaceutica, N.V. N-phenyl-N-(4-piperidinyl)amides
US4584303A (en) * 1984-04-09 1986-04-22 The Boc Group, Inc. N-aryl-N-(4-piperidinyl)amides and pharmaceutical compositions and method employing such compounds
FR2608602A1 (fr) * 1986-12-23 1988-06-24 Cerm Cent Europ Rech Mauvernay Nouvelles 3-piperidineamines ou 3-azepineamines substituees, leur preparation et leurs applications en therapeutique
US4849521A (en) * 1987-11-02 1989-07-18 Boc, Inc. Stereoselective preparation of 3-substituted-4-piperidine compounds and derivatives
US4791121A (en) * 1987-11-02 1988-12-13 The Boc Group, Inc. 4-phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
US5013742A (en) * 1987-11-02 1991-05-07 Boc, Inc. 4-phenyl-4-N-(phenyl) amido piperidine derivatives and pharmaceutical compositions and method employing such compounds
USRE33495E (en) * 1987-11-02 1990-12-18 Boc, Inc. Stereoselective preparation of 3-substituted-4-anilino-piperidine compounds and derivatives
US4957929A (en) * 1987-11-02 1990-09-18 Boc, Inc. 4-phenyl-4-[N-(phenyl)amido]piperidine compounds and pharmaceutical compositions employing such compounds
US4921864A (en) * 1987-11-02 1990-05-01 Boc, Inc. 4-Phenyl-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
US4801615A (en) * 1987-12-31 1989-01-31 The Boc Group, Inc. 4-heterohexacyclic-4-(N-(phenyl)amido) piperidine derivatives and pharmaceutical compositions and method employing such compounds
US4791120A (en) * 1987-12-31 1988-12-13 The Boc Group, Inc. 4-heteropentacyclic-4-[N-(phenyl)amino] piperidine derivatives and pharmaceutical compositions and method employing such compounds
US5019583A (en) * 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics
USRE34201E (en) * 1989-04-20 1993-03-23 Anaquest, Inc. N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds
US5053411A (en) * 1989-04-20 1991-10-01 Anaquest, Inc. N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides and pharmaceutical compositions and methods employing such compounds
US5145967A (en) * 1989-04-20 1992-09-08 Anaquest, Inc. Method for preparing 4-alkoxyalkyl-4-phenylaminopiperdines and derivatives thereof
US5100903A (en) * 1989-05-12 1992-03-31 Anaquest, Inc. N-aryl-n-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds
US4994471A (en) * 1989-05-12 1991-02-19 Boc, Inc. N-aryl-N-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds
US4939161A (en) * 1989-05-12 1990-07-03 Boc, Inc. Analgesic N-aryl-N-[1-substituted-3,5-dimethyl-4-piperidinyl]amides
US5039804A (en) * 1989-12-13 1991-08-13 Glaxo Inc. Preparation of substituted alkali metal piperidine-4-carboxylates
US5126455A (en) * 1989-12-13 1992-06-30 Glaxo Inc. Preparation of substituted alkali metal piperidine-4-carboxylates
US5214148A (en) * 1990-12-18 1993-05-25 Glaxo Inc. Analgesic N-phenyl-N-(3-OR1 -3-ME-4-piperidinyl)amides
US5130321A (en) * 1990-12-18 1992-07-14 Glaxo Inc. Analgesic n-phenyl-n-(3-or 1-3-me-4-piperidinyl)amides
FR2676054B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
GB9316863D0 (en) * 1993-08-13 1993-09-29 Glaxo Group Ltd Chemical process
US5489689A (en) * 1993-09-30 1996-02-06 Mallinckrodt Chemical, Inc. Preparation of piperidine derivatives
US6835194B2 (en) * 1999-03-18 2004-12-28 Durect Corporation Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners
US6541021B1 (en) 1999-03-18 2003-04-01 Durect Corporation Devices and methods for pain management
AU3676000A (en) * 1999-04-09 2000-11-14 Mochida Pharmaceutical Co., Ltd. 4-hydroxypiperidine derivatives having antiarrhythmic effect
US7361666B2 (en) * 1999-05-25 2008-04-22 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
US6635661B2 (en) 2000-05-25 2003-10-21 Sepracor Inc. Heterocyclic analgesic compounds and methods of use thereof
US6677332B1 (en) 1999-05-25 2004-01-13 Sepracor, Inc. Heterocyclic analgesic compounds and methods of use thereof
ES2272354T3 (es) * 1999-12-06 2007-05-01 Mallinckrodt Inc. Metodos para la sintesis de alfentanilo,sufentanilo remifentanilo.
US7074803B2 (en) * 2001-03-02 2006-07-11 Durect Corporation Opioid formulations
US20040102476A1 (en) * 2002-11-25 2004-05-27 Chan Tai Wah High concentration formulations of opioids and opioid derivatives
US20090030041A1 (en) * 2004-09-14 2009-01-29 Toshihiro Takahashi N-substituted N-(4-piperidinyl) Amide Derivative
JP2008088057A (ja) * 2005-03-23 2008-04-17 Nippon Chemiphar Co Ltd Ｎ−置換−ｎ−（４−ピペリジニル）アミド誘導体
AU2006317591A1 (en) * 2005-11-17 2007-05-31 Mallinckrodt Inc. Process for synthesizing remifentanil
EP1984336A2 (en) * 2006-01-24 2008-10-29 Mallinckrodt, Inc. Process for synthesizing remifentanil
EP1867635A1 (en) * 2006-06-15 2007-12-19 Kern Pharma, S.L. Process for preparing remifentanil, intermediates thereof, use of said intermediates and processes for their preparation
US20080009782A1 (en) * 2006-06-28 2008-01-10 Alza Corporation Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
WO2008005423A1 (en) * 2006-07-03 2008-01-10 Cambrex Charles City, Inc. Improved method of making sufentanil
US20100048908A1 (en) * 2006-11-29 2010-02-25 Brian Kai-Ming Cheng Process for Remifentanil Synthesis
US20100056574A1 (en) * 2008-09-04 2010-03-04 Mallinckrodt Inc. Crystalline Forms of Sufentanil
WO2010053944A1 (en) * 2008-11-04 2010-05-14 Cambrex Charles City, Inc. Improved method of making piperidine derivatives
PL2616464T3 (pl) 2010-09-17 2018-05-30 Mallinckrodt Llc Udoskonalony sposób wytwarzania prekursora zasady sufentanilu
EP2455377B1 (de) 2010-11-11 2014-07-09 hameln rds gmbh Synthese von Fentanyl Analoga
CN103328038A (zh) 2010-12-01 2013-09-25 史拜诺莫度雷森公司 向神经解剖结构直接递送药剂
KR20150131244A (ko) * 2013-03-13 2015-11-24 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 스테이플드 및 스티치드 폴리펩티드 및 그의 용도
US10633336B2 (en) 2014-12-19 2020-04-28 The Broad Institute, Inc. Dopamine D2 receptor ligands
US10752588B2 (en) 2014-12-19 2020-08-25 The Broad Institute, Inc. Dopamine D2 receptor ligands
ES2806631T3 (es) 2015-05-27 2021-02-18 SpecGx LLC Preparación de citrato de sufentanilo y base de sufentanilo
CN106854203B (zh) * 2015-12-08 2020-12-01 江苏恩华药业股份有限公司 枸橼酸舒芬太尼的新晶型及其制备方法
SI3199523T1 (sl) 2016-01-29 2018-12-31 Bioka S.R.O. Nov postopek za pridobivanje n-fenil-n-(4-piperinidil)amidnih derivatov kot sta remifentanil in karfentanil
CN108503579B (zh) * 2018-03-28 2021-03-26 南京医科大学 芬太尼类似物及其应用
CN113214140B (zh) * 2020-02-03 2022-09-09 江苏谛奇医药科技有限公司 哌啶酰胺类衍生物、其药物组合物及其应用
JP2023537357A (ja) 2020-08-14 2023-08-31 ノバルティス アーゲー ヘテロアリール置換スピロピペリジニル誘導体及びその薬学的使用
CN114262320A (zh) * 2021-12-28 2022-04-01 宜昌人福药业有限责任公司 一种利用连续流微通道反应器制备苯胺基哌啶类药物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL284196A (pt) * 1961-10-10
US3171838A (en) * 1961-10-10 1965-03-02 Res Lab Dr C Janssen N V Aroylalkyl and hydroxyaralkyl derivatives of 4-(n-arylalkanamido)-piperidines and related compounds

Also Published As

Publication number Publication date
FR2303546B1 (pt) 1980-11-28
SE426486B (sv) 1983-01-24
CZ278060B6 (en) 1993-08-11
FI61481C (fi) 1982-08-10
NO760591L (pt) 1976-09-15
DE2610228C2 (pt) 1990-04-05
ATA184676A (de) 1980-04-15
AT359493B (de) 1980-11-10
PT64898A (en) 1976-04-01
PH12746A (en) 1979-08-09
NO146162B (no) 1982-05-03
DK110376A (da) 1976-09-15
NL7602612A (nl) 1976-09-16
JPS51115478A (en) 1976-10-12
CA1080232A (en) 1980-06-24
LU74511A1 (pt) 1976-09-01
JPS5946217B2 (ja) 1984-11-10
YU39960B (en) 1985-06-30
GB1538938A (en) 1979-01-24
NZ180096A (en) 1978-06-02
IL49204A (en) 1979-11-30
DE2610228A1 (de) 1976-09-30
BG28259A3 (en) 1980-03-25
IT1057988B (it) 1982-03-30
CZ163276A3 (en) 1993-03-17
DK148960B (da) 1985-12-02
IE42512L (en) 1976-09-14
NO146162C (no) 1982-08-11
US3998834A (en) 1976-12-21
AU1200676A (en) 1977-09-22
FI760646A (pt) 1976-09-15
PL102474B1 (pl) 1979-03-31
NL185279B (nl) 1989-10-02
NL185279C (nl) 1990-03-01
CH629486A5 (de) 1982-04-30
IL49204A0 (en) 1976-05-31
SU1227109A3 (ru) 1986-04-23
FI61481B (fi) 1982-04-30
HU172963B (hu) 1979-01-28
FR2303546A1 (fr) 1976-10-08
PT64898B (en) 1977-08-18
AU503632B2 (en) 1979-09-13
ES446034A1 (es) 1977-10-16
IE42512B1 (en) 1980-08-27
SE7602740L (sv) 1976-09-15
YU65276A (en) 1982-08-31

Similar Documents

Publication Publication Date Title
DK148960C (da) Analogifremgangsmaade til fremstilling af n-(4-piperidinyl)-n-phenyl-carbamoyl-derivater
DK494876A (da) Fremgangsmade til fremstilling af piperidinderivater
DK365176A (da) Fremgangsmade til fremstilling af pyrrolidinderivater
DK150155C (da) Analogifremgangsmaade til fremstilling af benzocycloamid-derivater
DK298176A (da) Fremgangsmade til fremstilling af 1,4-dihydropyrinderivater
DK149115C (da) Fremgangsmaade til fremstilling af polyolefiner
DK149107C (da) Analogifremgangsmaade til fremstilling af quinazolonderivater
DK145228C (da) Analogifremgangsmaade til fremstilling af 3-amino-4-deoxo-4-iminorifamycinderivater
DK154764C (da) Analogifremgangsmaade til fremstilling af 1-sulfonylbenzimidazol-derivater
DK562376A (da) Fremgangsmade til fremstilling af ergolinderivater
DK462376A (da) Fremgangsmade til fremstilling af 5-halogenpyrimidinderivater
DK155002C (da) Analogifremgangsmaade til fremstilling af salicylanilidderivater
DK517776A (da) Fremgangsmade til femstilling af heterocycliske forbindelser
DK415676A (da) Fremgangsmade til fremstilling af pilocarpiniumsalte
DK164476A (da) Fremgangsmade til fremstilling af piperazinylpyrazinforbindelser
DK360576A (da) Fremgangsmade til fremstilling af pyridinderivater
DK324776A (da) Fremgangsmade til fremstilling af 3-cyanoimino-3-aminopropionitriler
DK150478C (da) Analogifremgangsmaade til fremstilling af n-aryl-n-(4-piperidyl)-arylacetamidderivater
DK372576A (da) Fremgangsmade til fremstilling af polyaminforbindelser
DK305876A (da) Fremgangsmade til fremstilling af l-pyroglutamyl-l-prolinamid
DK97376A (da) Fremgangsmade til fremstilling af histidinderivater
DK267976A (da) Fremgangsmade til fremstilling af piperidiner
DK143137C (da) Fremgangsmaade til fremstilling af phosphitchlorider
DK143281C (da) Fremgangsmaade til fremstilling af phosphitchlorider
DK155598C (da) Fremgangsmaade til fremstilling af ethylchlorthioformiat

Legal Events

Date Code Title Description
PUP Patent expired