DK1487863T3 - Fremgangsmåde til oprensning af glycopeptidphosponatderivater - Google Patents

Fremgangsmåde til oprensning af glycopeptidphosponatderivater

Info

Publication number
DK1487863T3
DK1487863T3 DK02761476T DK02761476T DK1487863T3 DK 1487863 T3 DK1487863 T3 DK 1487863T3 DK 02761476 T DK02761476 T DK 02761476T DK 02761476 T DK02761476 T DK 02761476T DK 1487863 T3 DK1487863 T3 DK 1487863T3
Authority
DK
Denmark
Prior art keywords
glycopeptide
purification
phosphate derivatives
resin
methods
Prior art date
Application number
DK02761476T
Other languages
Danish (da)
English (en)
Inventor
Donald Schmidt Jr
Jeanmarie Donovan Sganga
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Application granted granted Critical
Publication of DK1487863T3 publication Critical patent/DK1487863T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK02761476T 2001-08-24 2002-08-23 Fremgangsmåde til oprensning af glycopeptidphosponatderivater DK1487863T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31471201P 2001-08-24 2001-08-24
PCT/US2002/026854 WO2003018608A2 (en) 2001-08-24 2002-08-23 Process for purifying glycopeptide phosphonate derivatives

Publications (1)

Publication Number Publication Date
DK1487863T3 true DK1487863T3 (da) 2009-07-13

Family

ID=23221118

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02761476T DK1487863T3 (da) 2001-08-24 2002-08-23 Fremgangsmåde til oprensning af glycopeptidphosponatderivater

Country Status (14)

Country Link
US (5) US7015307B2 (zh)
EP (1) EP1487863B1 (zh)
JP (1) JP4116547B2 (zh)
KR (1) KR100905009B1 (zh)
CN (1) CN100418980C (zh)
AT (1) ATE430159T1 (zh)
AU (1) AU2002326740A1 (zh)
CA (1) CA2457218C (zh)
DE (1) DE60232197D1 (zh)
DK (1) DK1487863T3 (zh)
ES (1) ES2324771T3 (zh)
NO (1) NO330734B1 (zh)
TW (1) TWI233932B (zh)
WO (1) WO2003018608A2 (zh)

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TWI233932B (en) * 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives
TWI342312B (en) * 2003-10-22 2011-05-21 Theravance Inc Hydrochloride salts of a glycopeptide phosphonate derivative
CA2588285A1 (en) 2004-11-29 2006-06-01 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives
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JP2011507959A (ja) * 2007-12-26 2011-03-10 レアド トヘラペウトイクス，インコーポレーテッド 抗菌薬としての新規半合成糖ペプチド
GB2465863A (en) * 2008-12-05 2010-06-09 Lead Therapeutics Inc Semi-synthetic heptapeptidic glycopeptides for the treatment of bacterial infections
CN103105327A (zh) * 2011-11-11 2013-05-15 中国科学院大连化学物理研究所 采用金属氧化物富集糖肽的通用方法
US9753436B2 (en) 2013-06-11 2017-09-05 Apple Inc. Rotary input mechanism for an electronic device
US9627163B2 (en) 2013-08-09 2017-04-18 Apple Inc. Tactile switch for an electronic device
CN104418941B (zh) * 2013-08-19 2017-11-07 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
WO2015122885A1 (en) 2014-02-12 2015-08-20 Bodhi Technology Ventures Llc Rejection of false turns of rotary inputs for electronic devices
US10190891B1 (en) 2014-07-16 2019-01-29 Apple Inc. Optical encoder for detecting rotational and axial movement
US10599101B2 (en) 2014-09-02 2020-03-24 Apple Inc. Wearable electronic device
TN2017000358A1 (en) 2015-02-23 2019-01-16 Theravance Biopharma Antibiotics Ip Llc Doses and methods of administering telavancin
CN105985412A (zh) * 2015-02-28 2016-10-05 爱斯医药科技(南京)有限公司 万古霉素衍生物、制备方法及其应用
JP6515185B2 (ja) 2015-03-05 2019-05-15 アップル インコーポレイテッドＡｐｐｌｅ Ｉｎｃ． 方向依存光学特性を有する光学エンコーダを有する時計、手首装着型電子デバイス及びウェラブル電子デバイス
KR102163612B1 (ko) 2015-03-08 2020-10-08 애플 인크. 회전 및 병진 가능한 입력 메커니즘을 갖는 시계
US10018966B2 (en) 2015-04-24 2018-07-10 Apple Inc. Cover member for an input mechanism of an electronic device
US9891651B2 (en) 2016-02-27 2018-02-13 Apple Inc. Rotatable input mechanism having adjustable output
CN107325159A (zh) * 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
US10551798B1 (en) 2016-05-17 2020-02-04 Apple Inc. Rotatable crown for an electronic device
US10061399B2 (en) 2016-07-15 2018-08-28 Apple Inc. Capacitive gap sensor ring for an input device
US10019097B2 (en) 2016-07-25 2018-07-10 Apple Inc. Force-detecting input structure
US10664074B2 (en) 2017-06-19 2020-05-26 Apple Inc. Contact-sensitive crown for an electronic watch
US10962935B1 (en) 2017-07-18 2021-03-30 Apple Inc. Tri-axis force sensor
US11360440B2 (en) 2018-06-25 2022-06-14 Apple Inc. Crown for an electronic watch
US11561515B2 (en) 2018-08-02 2023-01-24 Apple Inc. Crown for an electronic watch
US11181863B2 (en) 2018-08-24 2021-11-23 Apple Inc. Conductive cap for watch crown
CN211293787U (zh) 2018-08-24 2020-08-18 苹果公司 电子表
CN209625187U (zh) 2018-08-30 2019-11-12 苹果公司 电子手表和电子设备
US11194298B2 (en) 2018-08-30 2021-12-07 Apple Inc. Crown assembly for an electronic watch
US11194299B1 (en) 2019-02-12 2021-12-07 Apple Inc. Variable frictional feedback device for a digital crown of an electronic watch
US11550268B2 (en) 2020-06-02 2023-01-10 Apple Inc. Switch module for electronic crown assembly
US11269376B2 (en) 2020-06-11 2022-03-08 Apple Inc. Electronic device

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US4667024A (en) * 1983-07-13 1987-05-19 Smithkline Beckman Corporation Process for the preparation of purified vancomycin class antibiotics
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US4845104A (en) * 1986-11-20 1989-07-04 Merck & Co., Inc. Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones
US4845194A (en) * 1987-02-27 1989-07-04 Eli Lilly And Company Glycopeptide recovery process
US4874843A (en) * 1987-12-03 1989-10-17 Eli Lilly And Company Chromatographic purification process
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JP2577133B2 (ja) 1989-11-27 1997-01-29 スティフティング フォール ド テフニスヘ ウェッテンスハッペン 船舶のプロペラ
US5258495A (en) * 1990-07-10 1993-11-02 Abbott Laboratories Process for making vancomycin HC1
US5149784A (en) * 1990-07-10 1992-09-22 Abbott Laboratories Process for making vancomycin
DE4039451A1 (de) * 1990-12-11 1992-06-17 Hoechst Ag Metallocene mit bicyclischen cyclopentadienderivaten als liganden, verfahren zu ihrer herstellung und ihre verwendung als katalysatoren
ATE167871T1 (de) 1992-04-20 1998-07-15 Abbott Lab Verfahren zur herstellung von vancomycin
RU2145609C1 (ru) * 1994-01-28 2000-02-20 Эли Лилли Энд Компани Производные гликопептида или их соли, способ получения, фармацевтическая композиция
SI9500039B (sl) * 1995-02-07 2002-02-28 Lek, Nov kombiniran postopek čiščenja Vankomicin hidroklorida
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UA75083C2 (uk) * 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
TWI233932B (en) * 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives

Also Published As

Publication number Publication date
EP1487863B1 (en) 2009-04-29
US7015307B2 (en) 2006-03-21
US20060100415A1 (en) 2006-05-11
EP1487863A4 (en) 2007-08-29
ES2324771T3 (es) 2009-08-14
JP4116547B2 (ja) 2008-07-09
US20110257364A1 (en) 2011-10-20
ATE430159T1 (de) 2009-05-15
WO2003018608A3 (en) 2004-10-07
US20030119722A1 (en) 2003-06-26
CA2457218A1 (en) 2003-03-06
TWI233932B (en) 2005-06-11
NO20040768L (no) 2004-04-29
DE60232197D1 (de) 2009-06-10
US20080103290A1 (en) 2008-05-01
AU2002326740A1 (en) 2003-03-10
CN100418980C (zh) 2008-09-17
CA2457218C (en) 2011-08-02
WO2003018608A2 (en) 2003-03-06
US7375181B2 (en) 2008-05-20
CN1671732A (zh) 2005-09-21
WO2003018608A8 (en) 2003-04-24
EP1487863A2 (en) 2004-12-22
US7468420B2 (en) 2008-12-23
US7858583B2 (en) 2010-12-28
US20090215673A1 (en) 2009-08-27
NO330734B1 (no) 2011-06-27
KR100905009B1 (ko) 2009-06-29
JP2005505542A (ja) 2005-02-24
KR20040028998A (ko) 2004-04-03

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