DK1480970T3 - Quinolinderivater - Google Patents

Quinolinderivater

Info

Publication number
DK1480970T3
DK1480970T3 DK03714784T DK03714784T DK1480970T3 DK 1480970 T3 DK1480970 T3 DK 1480970T3 DK 03714784 T DK03714784 T DK 03714784T DK 03714784 T DK03714784 T DK 03714784T DK 1480970 T3 DK1480970 T3 DK 1480970T3
Authority
DK
Denmark
Prior art keywords
quinoline
Prior art date
Application number
DK03714784T
Other languages
Danish (da)
English (en)
Inventor
Peter Gull
Villar Esteban Pombo
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK1480970T3 publication Critical patent/DK1480970T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK03714784T 2002-03-07 2003-03-06 Quinolinderivater DK1480970T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02005117 2002-03-07
EP02005115 2002-03-07
PCT/EP2003/002321 WO2003074511A1 (en) 2002-03-07 2003-03-06 Quinoline derivatives

Publications (1)

Publication Number Publication Date
DK1480970T3 true DK1480970T3 (da) 2007-03-05

Family

ID=27790094

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03714784T DK1480970T3 (da) 2002-03-07 2003-03-06 Quinolinderivater

Country Status (28)

Country Link
US (2) US7399768B2 (enExample)
EP (1) EP1480970B1 (enExample)
JP (2) JP2005519117A (enExample)
KR (1) KR101027977B1 (enExample)
CN (2) CN1939915A (enExample)
AR (1) AR038730A1 (enExample)
AU (1) AU2003219023B2 (enExample)
BR (1) BR0308201A (enExample)
CA (2) CA2706618A1 (enExample)
CO (1) CO5611196A2 (enExample)
CY (1) CY1106409T1 (enExample)
DE (1) DE60311233T2 (enExample)
DK (1) DK1480970T3 (enExample)
EC (1) ECSP045271A (enExample)
EG (1) EG24415A (enExample)
ES (1) ES2279100T3 (enExample)
IL (1) IL163769A0 (enExample)
MX (1) MXPA04008666A (enExample)
MY (1) MY134325A (enExample)
NO (1) NO20044117L (enExample)
NZ (1) NZ534732A (enExample)
PE (1) PE20030927A1 (enExample)
PL (2) PL210336B1 (enExample)
PT (1) PT1480970E (enExample)
RU (1) RU2345991C2 (enExample)
SI (1) SI1480970T1 (enExample)
TW (1) TW200406401A (enExample)
WO (1) WO2003074511A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60328732D1 (de) * 2002-03-07 2009-09-17 Novartis Ag Chinolinderivate und ihre Anwendung bei Glaukom und Kurzsichtigkeit
KR102712887B1 (ko) 2017-11-24 2024-10-02 하. 룬드벡 아크티에셀스카브 파킨슨병의 치료에 사용하기 위한 새로운 카테콜아민 전구약물
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
CN113677675B (zh) 2019-05-21 2024-07-26 H.隆德贝克有限公司 用于治疗帕金森病的新儿茶酚胺前药
JP7562562B2 (ja) 2019-05-21 2024-10-07 ハー・ルンドベック・アクチエゼルスカベット パーキンソン病の治療に使用するための新規なカテコールアミンプロドラッグ
US12398106B2 (en) 2019-05-21 2025-08-26 H. Lundbeck A/S Catecholamine carbamate prodrugs for use in the treatment of parkinson's disease
EP3972970A1 (en) 2019-05-21 2022-03-30 H. Lundbeck A/S New catecholamine prodrugs for use in the treatment of parkinson's disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100555A (en) * 1991-02-07 2000-08-31 Hoechst Marion Roussel Inc N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them
GB9326010D0 (en) * 1993-12-21 1994-02-23 Sandoz Ltd Improvements in or relating to organic compounds
TW378209B (en) * 1996-07-08 2000-01-01 Novartis Ag Benzo[g]quinoline derivatives, their preparation and the pharmaceutical composition containing them
PE20030240A1 (es) * 2001-07-09 2003-04-16 Novartis Ag DERIVADOS DE BENZO [g] QUINOLINA

Also Published As

Publication number Publication date
CO5611196A2 (es) 2006-02-28
US20080255176A1 (en) 2008-10-16
WO2003074511A1 (en) 2003-09-12
CN1639148A (zh) 2005-07-13
PL210336B1 (pl) 2012-01-31
KR101027977B1 (ko) 2011-04-13
RU2345991C2 (ru) 2009-02-10
CN1939915A (zh) 2007-04-04
PE20030927A1 (es) 2003-12-26
CY1106409T1 (el) 2011-10-12
PL370915A1 (en) 2005-06-13
ES2279100T3 (es) 2007-08-16
CA2477720A1 (en) 2003-09-12
BR0308201A (pt) 2005-01-04
KR20040089615A (ko) 2004-10-21
CN1293070C (zh) 2007-01-03
JP2010095550A (ja) 2010-04-30
AU2003219023B2 (en) 2006-11-30
EP1480970A1 (en) 2004-12-01
DE60311233D1 (de) 2007-03-08
CA2706618A1 (en) 2003-09-12
AR038730A1 (es) 2005-01-26
MXPA04008666A (es) 2004-12-06
US20050234085A1 (en) 2005-10-20
MY134325A (en) 2007-12-31
PL394208A1 (pl) 2011-08-16
SI1480970T1 (sl) 2007-06-30
ECSP045271A (es) 2004-10-26
PT1480970E (pt) 2007-03-30
EG24415A (en) 2009-05-25
CA2477720C (en) 2010-09-21
IL163769A0 (en) 2005-12-18
PL215012B1 (pl) 2013-10-31
TW200406401A (en) 2004-05-01
US7399768B2 (en) 2008-07-15
EP1480970B1 (en) 2007-01-17
JP2005519117A (ja) 2005-06-30
NO20044117L (no) 2004-09-28
NZ534732A (en) 2006-05-26
AU2003219023A1 (en) 2003-09-16
DE60311233T2 (de) 2007-11-15
RU2004129767A (ru) 2005-06-27
HK1071364A1 (en) 2005-07-15

Similar Documents

Publication Publication Date Title
NO20042121D0 (no) Kinolinforbindelse
DE50313647D1 (de) Knochenfixationseinrichtumg
ATE534648T1 (de) C-6-modifizierte indazolylpyrrolotriazine
IS7524A (is) Históndeasetýlasahemlar
DE50305852D1 (de) Einspritzventil
DE60321537D1 (de) Schtrockner
DE60332465D1 (de) Aftstoffeinspritzdüse
DE50301200D1 (de) Wischblatt
IS7498A (is) ökulagsriti
DE60333552D1 (de) Münzverarbeitungssystem
DE60318186D1 (de) Wachsamkeitsriegel
DE60325671D1 (de) Bilderzeugunsgerät
DE60335555D1 (de) Enstands
DE50305301D1 (de) Einspritzventil
DE60231468D1 (de) Einachsgrubber
DE60309990D1 (de) Schraubbefestigungsstruktur
IS2943B (is) Fínasteríðsamsetningar
DE60311233D1 (de) Chinolinderivate
DE60332551D1 (de) Ic-tag
DE60326162D1 (de) Grasendophyten
DE60236137D1 (de) Gradationsverarbeitungsmethode
ATE469773T1 (de) Zugöse
FI5303U1 (fi) Ammesovitelma
DE60304326D1 (de) Wärmeniet
DE60205924D1 (de) Mikrogreifer