DK145676C - Analogifremgangsmaade til fremstilling af oxoalkyldialkylxanthiner - Google Patents
Analogifremgangsmaade til fremstilling af oxoalkyldialkylxanthinerInfo
- Publication number
- DK145676C DK145676C DK321574A DK321574A DK145676C DK 145676 C DK145676 C DK 145676C DK 321574 A DK321574 A DK 321574A DK 321574 A DK321574 A DK 321574A DK 145676 C DK145676 C DK 145676C
- Authority
- DK
- Denmark
- Prior art keywords
- choydialychylxanthines
- oxoal
- preparation
- analogy procedure
- analogy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2330742 | 1973-06-16 | ||
| DE2330742A DE2330742C2 (de) | 1973-06-16 | 1973-06-16 | 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK321574A DK321574A (es) | 1975-02-10 |
| DK145676B DK145676B (da) | 1983-01-24 |
| DK145676C true DK145676C (da) | 1983-08-01 |
Family
ID=5884209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK321574A DK145676C (da) | 1973-06-16 | 1974-06-14 | Analogifremgangsmaade til fremstilling af oxoalkyldialkylxanthiner |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4289776A (es) |
| JP (1) | JPS5233120B2 (es) |
| AR (3) | AR208179A1 (es) |
| AT (1) | AT334388B (es) |
| BE (1) | BE816332A (es) |
| CH (2) | CH612969A5 (es) |
| DE (1) | DE2330742C2 (es) |
| DK (1) | DK145676C (es) |
| ES (1) | ES427171A1 (es) |
| FI (1) | FI58920C (es) |
| FR (1) | FR2233065B1 (es) |
| GB (1) | GB1470220A (es) |
| IE (1) | IE39898B1 (es) |
| NL (1) | NL182806C (es) |
| NO (1) | NO140300C (es) |
| SE (1) | SE423631B (es) |
| ZA (1) | ZA743760B (es) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH608236A5 (es) * | 1974-01-22 | 1978-12-29 | Wuelfing J A Fa | |
| DE2507554A1 (de) * | 1975-02-21 | 1976-09-02 | Wuelfing J A Fa | 7-(oxoalkyl)-1,3-dialkylxanthine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE2507555A1 (de) * | 1975-02-21 | 1976-09-02 | Wuelfing J A Fa | 7-(oxoalkyl)-1,3-dialkylxanthine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel |
| JPS54112893A (en) * | 1978-02-21 | 1979-09-04 | Kohjin Co Ltd | Preparation of 1-(5'-oxohexyl)-3,7-diethylxanthine |
| EP0005015B1 (en) * | 1978-04-22 | 1986-10-29 | BEECHAM - WUELFING GmbH & Co. KG | Use of a xanthine derivate in the manufacture of a medicament |
| IL59665A0 (en) * | 1979-04-05 | 1980-06-30 | Wuelfing J Kg | Xanthine derivatives,process for their preparation and their use in pharmaceutical compositions |
| DE3173289D1 (en) | 1980-06-21 | 1986-02-06 | Beecham Wuelfing Gmbh & Co Kg | Xanthine derivatives, pharmaceutical compositions containing them and a process for their preparation |
| US4636507A (en) * | 1984-04-30 | 1987-01-13 | Hoechst-Roussel Pharmaceuticals Inc. | Host defense mechanism enhancement |
| JPH062675B2 (ja) * | 1985-04-05 | 1994-01-12 | ヘキストジヤパン株式会社 | 記憶障害治療剤 |
| GB8621869D0 (en) * | 1986-09-11 | 1986-10-15 | Beecham Group Plc | Treatment |
| JPS63225317A (ja) * | 1986-10-06 | 1988-09-20 | Hoechst Japan Kk | 抗消化性潰瘍剤 |
| IT1197516B (it) * | 1986-12-24 | 1988-11-30 | Abc Ist Biolog Chem Spa | Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono |
| US4965271A (en) * | 1986-12-31 | 1990-10-23 | Hoechst Roussel Pharmaceuticals, Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
| US5096906A (en) * | 1986-12-31 | 1992-03-17 | University Of Virginia Alumni Patents Foundation | Method of inhibiting the activity of leukocyte derived cytokines |
| CA2030112A1 (en) * | 1989-11-24 | 1991-05-25 | Yasuo Ito | Xanthine compound, method for preparing thereof, and a pharmaceutical composition comprising the same |
| DE3942872A1 (de) * | 1989-12-23 | 1991-06-27 | Hoechst Ag | Verfahren zur enantioselektiven darstellung von ((omega)-1)-hydroxyalkylxanthinen |
| US6420374B1 (en) | 1990-11-30 | 2002-07-16 | Fred Hutchinson Cancer Research Center | Use of xanthines as immunosuppressants and to inhibit allograft reactions |
| ATE142498T1 (de) * | 1991-05-23 | 1996-09-15 | Hoechst Ag | Die verwendung von 1-(5-oxohexyl)-3-methyl-7-n- propyl-xanthin in der gefässchirurgie |
| MX9203323A (es) * | 1991-07-11 | 1994-07-29 | Hoechst Ag | El empleo de derivados de xantina para el tratamiento de lesiones secundarias de las celulas nerviosas y trastornos funcionales despues de traumas craneo-cerebrales. |
| JP2549480B2 (ja) * | 1991-12-10 | 1996-10-30 | ヘキストジャパン株式会社 | 排尿障害改善剤 |
| EP0570831A2 (de) * | 1992-05-20 | 1993-11-24 | Hoechst Aktiengesellschaft | Verwendung von Xanthinderivaten zur Behandlung von Nervenschädigungen nach Unterbrechung der Blutzirkulation |
| US5670506A (en) * | 1993-04-05 | 1997-09-23 | Cell Therapeutics, Inc. | Halogen, isothiocyanate or azide substituted xanthines |
| US6020337A (en) * | 1993-04-05 | 2000-02-01 | Cell Therapeutics, Inc. | Electronegative-substituted long chain xanthine compounds |
| WO1995020589A1 (en) * | 1994-01-28 | 1995-08-03 | Cell Therapeutics, Inc. | Cell signaling inhibitors |
| US5762953A (en) * | 1996-08-22 | 1998-06-09 | Theratech, Inc. | Transdermal propentofylline compositions for the treatment of Alzheimers disease |
| DE19707655A1 (de) * | 1997-02-26 | 1998-08-27 | Hoechst Ag | Kombinationspräparat zur Anwendung bei Demenz |
| US20040110776A1 (en) * | 2002-02-22 | 2004-06-10 | Iok-Hou Pang | Use of propentofylline to control intraocular pressure |
| MX2010009300A (es) | 2008-02-29 | 2010-11-05 | Concert Pharmaceuticals Inc | Derivados de xantina substituidos. |
| US20110053961A1 (en) | 2009-02-27 | 2011-03-03 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
| EP2473052A4 (en) | 2009-09-02 | 2013-03-20 | Concert Pharmaceuticals Inc | SUBSTITUTED XANTHINE DERIVATIVES |
| EP3397640B1 (en) * | 2015-12-29 | 2021-08-04 | INSERM - Institut National de la Santé et de la Recherche Médicale | Xanthine derivative inhibitors of bet proteins |
| CN112724160A (zh) * | 2021-03-19 | 2021-04-30 | 赤峰经方医药技术开发有限责任公司 | 一种己酮可可碱杂质的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH325292A (de) * | 1953-10-21 | 1957-10-31 | Geigy Ag J R | Verfahren zur Herstellung von 7-Oxyalkyl-xanthinderivaten |
| FR1211333A (fr) * | 1955-10-19 | 1960-03-15 | Boehringer Sohn Ingelheim | Perfectionnements apportés aux procédés pour fabriquer des oxyalcoylxanthines |
| DE1545689C2 (de) | 1964-09-05 | 1982-07-01 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von 2-Methyl-3-carbäthoxy-5,6-dihydropyran |
| US3737433A (en) | 1964-09-05 | 1973-06-05 | Albert Ag Chem Werke | Certain oxoalkyldimethylxanthines |
| DE1233405B (de) | 1964-09-05 | 1967-02-02 | Albert Ag Chem Werke | Verfahren zur Herstellung von 7-(Oxoalkyl)-1, 3-dimethylxanthinen |
| US3422107A (en) | 1964-09-05 | 1969-01-14 | Albert Ag Chem Werke | Certain oxoalkyldimethylxanthines and a process for the preparation thereof |
| US3864469A (en) * | 1967-12-16 | 1975-02-04 | Hoechst Ag | Xanthines in pharmaceutical preparations and for stabilization of vitamins |
| DE1810705C3 (de) * | 1968-11-25 | 1980-11-27 | Hoechst Ag, 6000 Frankfurt | Stabilisierung von Vitaminen |
| DE1911279A1 (de) * | 1969-03-05 | 1970-11-12 | Eckert Dr Theodor | Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen |
-
1973
- 1973-06-16 DE DE2330742A patent/DE2330742C2/de not_active Expired
-
1974
- 1974-01-01 AR AR254209A patent/AR208179A1/es active
- 1974-06-11 NO NO742121A patent/NO140300C/no unknown
- 1974-06-11 ES ES427171A patent/ES427171A1/es not_active Expired
- 1974-06-12 ZA ZA00743760A patent/ZA743760B/xx unknown
- 1974-06-13 NL NLAANVRAGE7407890,A patent/NL182806C/xx not_active IP Right Cessation
- 1974-06-14 IE IE1258/74A patent/IE39898B1/xx unknown
- 1974-06-14 CH CH123978A patent/CH612969A5/xx not_active IP Right Cessation
- 1974-06-14 FR FR7420679A patent/FR2233065B1/fr not_active Expired
- 1974-06-14 AT AT491874A patent/AT334388B/de not_active IP Right Cessation
- 1974-06-14 SE SE7407913A patent/SE423631B/xx not_active IP Right Cessation
- 1974-06-14 GB GB2655574A patent/GB1470220A/en not_active Expired
- 1974-06-14 CH CH748211A patent/CH608807A5/xx not_active IP Right Cessation
- 1974-06-14 FI FI1819/74A patent/FI58920C/fi active
- 1974-06-14 JP JP49067265A patent/JPS5233120B2/ja not_active Expired
- 1974-06-14 BE BE145417A patent/BE816332A/xx not_active IP Right Cessation
- 1974-06-14 DK DK321574A patent/DK145676C/da active
-
1975
- 1975-08-22 AR AR260112A patent/AR209319A1/es active
- 1975-08-22 AR AR260113A patent/AR209320A1/es active
-
1979
- 1979-04-23 US US06/032,536 patent/US4289776A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IE39898B1 (en) | 1979-01-31 |
| FR2233065A1 (es) | 1975-01-10 |
| BE816332A (fr) | 1974-12-16 |
| AR208179A1 (es) | 1976-12-09 |
| SE7407913L (es) | 1974-12-17 |
| AU7014774A (en) | 1975-12-18 |
| FI58920B (fi) | 1981-01-30 |
| CH612969A5 (es) | 1979-08-31 |
| ES427171A1 (es) | 1976-07-16 |
| GB1470220A (en) | 1977-04-14 |
| FR2233065B1 (es) | 1978-07-21 |
| NO140300C (no) | 1979-08-08 |
| SE423631B (sv) | 1982-05-17 |
| DE2330742C2 (de) | 1982-07-29 |
| IE39898L (en) | 1974-12-16 |
| JPS5047992A (es) | 1975-04-28 |
| AT334388B (de) | 1976-01-10 |
| FI181974A (es) | 1974-12-17 |
| NL182806B (nl) | 1987-12-16 |
| DK321574A (es) | 1975-02-10 |
| US4289776A (en) | 1981-09-15 |
| AR209320A1 (es) | 1977-04-15 |
| DK145676B (da) | 1983-01-24 |
| NO742121L (es) | 1975-01-13 |
| CH608807A5 (es) | 1979-01-31 |
| ATA491874A (de) | 1976-05-15 |
| ZA743760B (en) | 1975-06-25 |
| NL182806C (nl) | 1988-05-16 |
| JPS5233120B2 (es) | 1977-08-26 |
| NL7407890A (es) | 1974-12-18 |
| NO140300B (no) | 1979-04-30 |
| DE2330742A1 (de) | 1975-01-09 |
| AR209319A1 (es) | 1977-04-15 |
| FI58920C (fi) | 1981-05-11 |
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