SE423631B - Forfarande for framstellning av oxaalhyl-dialkylxantiner - Google Patents

Forfarande for framstellning av oxaalhyl-dialkylxantiner

Info

Publication number
SE423631B
SE423631B SE7407913A SE7407913A SE423631B SE 423631 B SE423631 B SE 423631B SE 7407913 A SE7407913 A SE 7407913A SE 7407913 A SE7407913 A SE 7407913A SE 423631 B SE423631 B SE 423631B
Authority
SE
Sweden
Prior art keywords
oxalhyl
dialkylxantines
procedure
preparation
oxalhyl dialkylxantines
Prior art date
Application number
SE7407913A
Other languages
English (en)
Swedish (sv)
Other versions
SE7407913L (es
Inventor
W Mohler
M Jayme
J Komarek
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of SE7407913L publication Critical patent/SE7407913L/xx
Publication of SE423631B publication Critical patent/SE423631B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SE7407913A 1973-06-16 1974-06-14 Forfarande for framstellning av oxaalhyl-dialkylxantiner SE423631B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2330742A DE2330742C2 (de) 1973-06-16 1973-06-16 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Publications (2)

Publication Number Publication Date
SE7407913L SE7407913L (es) 1974-12-17
SE423631B true SE423631B (sv) 1982-05-17

Family

ID=5884209

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7407913A SE423631B (sv) 1973-06-16 1974-06-14 Forfarande for framstellning av oxaalhyl-dialkylxantiner

Country Status (17)

Country Link
US (1) US4289776A (es)
JP (1) JPS5233120B2 (es)
AR (3) AR208179A1 (es)
AT (1) AT334388B (es)
BE (1) BE816332A (es)
CH (2) CH612969A5 (es)
DE (1) DE2330742C2 (es)
DK (1) DK145676C (es)
ES (1) ES427171A1 (es)
FI (1) FI58920C (es)
FR (1) FR2233065B1 (es)
GB (1) GB1470220A (es)
IE (1) IE39898B1 (es)
NL (1) NL182806C (es)
NO (1) NO140300C (es)
SE (1) SE423631B (es)
ZA (1) ZA743760B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608236A5 (es) * 1974-01-22 1978-12-29 Wuelfing J A Fa
DE2507554A1 (de) * 1975-02-21 1976-09-02 Wuelfing J A Fa 7-(oxoalkyl)-1,3-dialkylxanthine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2507555A1 (de) * 1975-02-21 1976-09-02 Wuelfing J A Fa 7-(oxoalkyl)-1,3-dialkylxanthine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel
JPS54112893A (en) * 1978-02-21 1979-09-04 Kohjin Co Ltd Preparation of 1-(5'-oxohexyl)-3,7-diethylxanthine
EP0005015B1 (en) * 1978-04-22 1986-10-29 BEECHAM - WUELFING GmbH & Co. KG Use of a xanthine derivate in the manufacture of a medicament
IL59665A0 (en) * 1979-04-05 1980-06-30 Wuelfing J Kg Xanthine derivatives,process for their preparation and their use in pharmaceutical compositions
DE3173289D1 (en) 1980-06-21 1986-02-06 Beecham Wuelfing Gmbh & Co Kg Xanthine derivatives, pharmaceutical compositions containing them and a process for their preparation
US4636507A (en) * 1984-04-30 1987-01-13 Hoechst-Roussel Pharmaceuticals Inc. Host defense mechanism enhancement
JPH062675B2 (ja) * 1985-04-05 1994-01-12 ヘキストジヤパン株式会社 記憶障害治療剤
GB8621869D0 (en) * 1986-09-11 1986-10-15 Beecham Group Plc Treatment
JPS63225317A (ja) * 1986-10-06 1988-09-20 Hoechst Japan Kk 抗消化性潰瘍剤
IT1197516B (it) * 1986-12-24 1988-11-30 Abc Ist Biolog Chem Spa Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono
US4965271A (en) * 1986-12-31 1990-10-23 Hoechst Roussel Pharmaceuticals, Inc. Method of inhibiting the activity of leukocyte derived cytokines
US5096906A (en) * 1986-12-31 1992-03-17 University Of Virginia Alumni Patents Foundation Method of inhibiting the activity of leukocyte derived cytokines
CA2030112A1 (en) * 1989-11-24 1991-05-25 Yasuo Ito Xanthine compound, method for preparing thereof, and a pharmaceutical composition comprising the same
DE3942872A1 (de) * 1989-12-23 1991-06-27 Hoechst Ag Verfahren zur enantioselektiven darstellung von ((omega)-1)-hydroxyalkylxanthinen
US6420374B1 (en) 1990-11-30 2002-07-16 Fred Hutchinson Cancer Research Center Use of xanthines as immunosuppressants and to inhibit allograft reactions
ATE142498T1 (de) * 1991-05-23 1996-09-15 Hoechst Ag Die verwendung von 1-(5-oxohexyl)-3-methyl-7-n- propyl-xanthin in der gefässchirurgie
MX9203323A (es) * 1991-07-11 1994-07-29 Hoechst Ag El empleo de derivados de xantina para el tratamiento de lesiones secundarias de las celulas nerviosas y trastornos funcionales despues de traumas craneo-cerebrales.
JP2549480B2 (ja) * 1991-12-10 1996-10-30 ヘキストジャパン株式会社 排尿障害改善剤
EP0570831A2 (de) * 1992-05-20 1993-11-24 Hoechst Aktiengesellschaft Verwendung von Xanthinderivaten zur Behandlung von Nervenschädigungen nach Unterbrechung der Blutzirkulation
US5670506A (en) * 1993-04-05 1997-09-23 Cell Therapeutics, Inc. Halogen, isothiocyanate or azide substituted xanthines
US6020337A (en) * 1993-04-05 2000-02-01 Cell Therapeutics, Inc. Electronegative-substituted long chain xanthine compounds
WO1995020589A1 (en) * 1994-01-28 1995-08-03 Cell Therapeutics, Inc. Cell signaling inhibitors
US5762953A (en) * 1996-08-22 1998-06-09 Theratech, Inc. Transdermal propentofylline compositions for the treatment of Alzheimers disease
DE19707655A1 (de) * 1997-02-26 1998-08-27 Hoechst Ag Kombinationspräparat zur Anwendung bei Demenz
US20040110776A1 (en) * 2002-02-22 2004-06-10 Iok-Hou Pang Use of propentofylline to control intraocular pressure
MX2010009300A (es) 2008-02-29 2010-11-05 Concert Pharmaceuticals Inc Derivados de xantina substituidos.
US20110053961A1 (en) 2009-02-27 2011-03-03 Concert Pharmaceuticals, Inc. Substituted xanthine derivatives
EP2473052A4 (en) 2009-09-02 2013-03-20 Concert Pharmaceuticals Inc SUBSTITUTED XANTHINE DERIVATIVES
EP3397640B1 (en) * 2015-12-29 2021-08-04 INSERM - Institut National de la Santé et de la Recherche Médicale Xanthine derivative inhibitors of bet proteins
CN112724160A (zh) * 2021-03-19 2021-04-30 赤峰经方医药技术开发有限责任公司 一种己酮可可碱杂质的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH325292A (de) * 1953-10-21 1957-10-31 Geigy Ag J R Verfahren zur Herstellung von 7-Oxyalkyl-xanthinderivaten
FR1211333A (fr) * 1955-10-19 1960-03-15 Boehringer Sohn Ingelheim Perfectionnements apportés aux procédés pour fabriquer des oxyalcoylxanthines
DE1545689C2 (de) 1964-09-05 1982-07-01 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von 2-Methyl-3-carbäthoxy-5,6-dihydropyran
US3737433A (en) 1964-09-05 1973-06-05 Albert Ag Chem Werke Certain oxoalkyldimethylxanthines
DE1233405B (de) 1964-09-05 1967-02-02 Albert Ag Chem Werke Verfahren zur Herstellung von 7-(Oxoalkyl)-1, 3-dimethylxanthinen
US3422107A (en) 1964-09-05 1969-01-14 Albert Ag Chem Werke Certain oxoalkyldimethylxanthines and a process for the preparation thereof
US3864469A (en) * 1967-12-16 1975-02-04 Hoechst Ag Xanthines in pharmaceutical preparations and for stabilization of vitamins
DE1810705C3 (de) * 1968-11-25 1980-11-27 Hoechst Ag, 6000 Frankfurt Stabilisierung von Vitaminen
DE1911279A1 (de) * 1969-03-05 1970-11-12 Eckert Dr Theodor Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen

Also Published As

Publication number Publication date
IE39898B1 (en) 1979-01-31
FR2233065A1 (es) 1975-01-10
BE816332A (fr) 1974-12-16
AR208179A1 (es) 1976-12-09
SE7407913L (es) 1974-12-17
AU7014774A (en) 1975-12-18
FI58920B (fi) 1981-01-30
CH612969A5 (es) 1979-08-31
ES427171A1 (es) 1976-07-16
GB1470220A (en) 1977-04-14
FR2233065B1 (es) 1978-07-21
NO140300C (no) 1979-08-08
DE2330742C2 (de) 1982-07-29
IE39898L (en) 1974-12-16
JPS5047992A (es) 1975-04-28
AT334388B (de) 1976-01-10
DK145676C (da) 1983-08-01
FI181974A (es) 1974-12-17
NL182806B (nl) 1987-12-16
DK321574A (es) 1975-02-10
US4289776A (en) 1981-09-15
AR209320A1 (es) 1977-04-15
DK145676B (da) 1983-01-24
NO742121L (es) 1975-01-13
CH608807A5 (es) 1979-01-31
ATA491874A (de) 1976-05-15
ZA743760B (en) 1975-06-25
NL182806C (nl) 1988-05-16
JPS5233120B2 (es) 1977-08-26
NL7407890A (es) 1974-12-18
NO140300B (no) 1979-04-30
DE2330742A1 (de) 1975-01-09
AR209319A1 (es) 1977-04-15
FI58920C (fi) 1981-05-11

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