ATA491874A - Verfahren zur herstellung von neuen 1- oder 7-(omega-1)-oxoalkyl-3,7 (oder 1,3)-dialkylxanthinen - Google Patents
Verfahren zur herstellung von neuen 1- oder 7-(omega-1)-oxoalkyl-3,7 (oder 1,3)-dialkylxanthinenInfo
- Publication number
- ATA491874A ATA491874A AT491874A AT491874A ATA491874A AT A491874 A ATA491874 A AT A491874A AT 491874 A AT491874 A AT 491874A AT 491874 A AT491874 A AT 491874A AT A491874 A ATA491874 A AT A491874A
- Authority
- AT
- Austria
- Prior art keywords
- dialkylxanthines
- oxoalkyl
- omega
- preparing new
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT738975A AT334392B (de) | 1973-06-16 | 1975-09-26 | Verfahren zur herstellung von neuen 1- oder 7-(omega-1)-oxoalkyl-3,7 (oder 1,3-)-dialkylxanthinen |
AT738875A AT334391B (de) | 1973-06-16 | 1975-09-26 | Verfahren zur herstellung von neuen 1- oder 7-(omega-1)-oxoalkyl-3,7-(oder 1,3-)dialkylxanthinen |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2330742A DE2330742C2 (de) | 1973-06-16 | 1973-06-16 | 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
AT334388B AT334388B (de) | 1976-01-10 |
ATA491874A true ATA491874A (de) | 1976-05-15 |
Family
ID=5884209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT491874A AT334388B (de) | 1973-06-16 | 1974-06-14 | Verfahren zur herstellung von neuen 1- oder 7-(omega-1)-oxoalkyl-3,7 (oder 1,3)-dialkylxanthinen |
Country Status (17)
Country | Link |
---|---|
US (1) | US4289776A (de) |
JP (1) | JPS5233120B2 (de) |
AR (3) | AR208179A1 (de) |
AT (1) | AT334388B (de) |
BE (1) | BE816332A (de) |
CH (2) | CH608807A5 (de) |
DE (1) | DE2330742C2 (de) |
DK (1) | DK145676C (de) |
ES (1) | ES427171A1 (de) |
FI (1) | FI58920C (de) |
FR (1) | FR2233065B1 (de) |
GB (1) | GB1470220A (de) |
IE (1) | IE39898B1 (de) |
NL (1) | NL182806C (de) |
NO (1) | NO140300C (de) |
SE (1) | SE423631B (de) |
ZA (1) | ZA743760B (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH608236A5 (de) * | 1974-01-22 | 1978-12-29 | Wuelfing J A Fa | |
DE2507554A1 (de) * | 1975-02-21 | 1976-09-02 | Wuelfing J A Fa | 7-(oxoalkyl)-1,3-dialkylxanthine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE2507555A1 (de) * | 1975-02-21 | 1976-09-02 | Wuelfing J A Fa | 7-(oxoalkyl)-1,3-dialkylxanthine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel |
JPS54112893A (en) * | 1978-02-21 | 1979-09-04 | Kohjin Co Ltd | Preparation of 1-(5'-oxohexyl)-3,7-diethylxanthine |
EP0005015B1 (de) * | 1978-04-22 | 1986-10-29 | BEECHAM - WUELFING GmbH & Co. KG | Verwendung eines Xanthinderivats für die Herstellung eines Arzneimittels |
IL59665A0 (en) * | 1979-04-05 | 1980-06-30 | Wuelfing J Kg | Xanthine derivatives,process for their preparation and their use in pharmaceutical compositions |
EP0157098A1 (de) | 1980-06-21 | 1985-10-09 | Beecham Wuelfing GmbH & Co KG | Xanthin-Derivate, diese enthaltende pharmazeutische Zusammensetzungen und ein Verfahren zu ihrer Herstellung |
US4636507A (en) * | 1984-04-30 | 1987-01-13 | Hoechst-Roussel Pharmaceuticals Inc. | Host defense mechanism enhancement |
JPH062675B2 (ja) * | 1985-04-05 | 1994-01-12 | ヘキストジヤパン株式会社 | 記憶障害治療剤 |
GB8621869D0 (en) * | 1986-09-11 | 1986-10-15 | Beecham Group Plc | Treatment |
JPS63225317A (ja) * | 1986-10-06 | 1988-09-20 | Hoechst Japan Kk | 抗消化性潰瘍剤 |
IT1197516B (it) * | 1986-12-24 | 1988-11-30 | Abc Ist Biolog Chem Spa | Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono |
US5096906A (en) * | 1986-12-31 | 1992-03-17 | University Of Virginia Alumni Patents Foundation | Method of inhibiting the activity of leukocyte derived cytokines |
US4965271A (en) * | 1986-12-31 | 1990-10-23 | Hoechst Roussel Pharmaceuticals, Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
CA2030112A1 (en) * | 1989-11-24 | 1991-05-25 | Yasuo Ito | Xanthine compound, method for preparing thereof, and a pharmaceutical composition comprising the same |
DE3942872A1 (de) * | 1989-12-23 | 1991-06-27 | Hoechst Ag | Verfahren zur enantioselektiven darstellung von ((omega)-1)-hydroxyalkylxanthinen |
US6420374B1 (en) | 1990-11-30 | 2002-07-16 | Fred Hutchinson Cancer Research Center | Use of xanthines as immunosuppressants and to inhibit allograft reactions |
DE59207086D1 (de) * | 1991-05-23 | 1996-10-17 | Hoechst Ag | Die Verwendung von 1-(5-Oxohexyl)-3-methyl-7-n-propyl-xanthin in der Gefässchirurgie |
MX9203323A (es) * | 1991-07-11 | 1994-07-29 | Hoechst Ag | El empleo de derivados de xantina para el tratamiento de lesiones secundarias de las celulas nerviosas y trastornos funcionales despues de traumas craneo-cerebrales. |
JP2549480B2 (ja) * | 1991-12-10 | 1996-10-30 | ヘキストジャパン株式会社 | 排尿障害改善剤 |
EP0570831A2 (de) * | 1992-05-20 | 1993-11-24 | Hoechst Aktiengesellschaft | Verwendung von Xanthinderivaten zur Behandlung von Nervenschädigungen nach Unterbrechung der Blutzirkulation |
US6020337A (en) * | 1993-04-05 | 2000-02-01 | Cell Therapeutics, Inc. | Electronegative-substituted long chain xanthine compounds |
US5670506A (en) * | 1993-04-05 | 1997-09-23 | Cell Therapeutics, Inc. | Halogen, isothiocyanate or azide substituted xanthines |
AU1868195A (en) * | 1994-01-28 | 1995-08-15 | Cell Therapeutics, Inc. | Cell signaling inhibitors |
US5762953A (en) * | 1996-08-22 | 1998-06-09 | Theratech, Inc. | Transdermal propentofylline compositions for the treatment of Alzheimers disease |
DE19707655A1 (de) * | 1997-02-26 | 1998-08-27 | Hoechst Ag | Kombinationspräparat zur Anwendung bei Demenz |
US20040110776A1 (en) * | 2002-02-22 | 2004-06-10 | Iok-Hou Pang | Use of propentofylline to control intraocular pressure |
BRPI0908107A2 (pt) | 2008-02-29 | 2019-09-24 | Concert Pharmaceuticals Inc | composto derivado de xantina substituída, composição farmacêutica que compreende esse composto, métodos de tratamento de uma enfermidade ou condição em um paciente com necessidade do mesmo, método de tratamento de enfermidade crônica dos rins, do fígado, relacionada com diabetes e de claudicação intermitente |
US20110053961A1 (en) | 2009-02-27 | 2011-03-03 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
EP2473052A4 (de) | 2009-09-02 | 2013-03-20 | Concert Pharmaceuticals Inc | Substituierte xanthinderivate |
EP3397640B1 (de) * | 2015-12-29 | 2021-08-04 | INSERM - Institut National de la Santé et de la Recherche Médicale | Xanthinderivatinhibitoren von bet-proteine |
CN112724160A (zh) * | 2021-03-19 | 2021-04-30 | 赤峰经方医药技术开发有限责任公司 | 一种己酮可可碱杂质的制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH325292A (de) * | 1953-10-21 | 1957-10-31 | Geigy Ag J R | Verfahren zur Herstellung von 7-Oxyalkyl-xanthinderivaten |
FR1211333A (fr) * | 1955-10-19 | 1960-03-15 | Boehringer Sohn Ingelheim | Perfectionnements apportés aux procédés pour fabriquer des oxyalcoylxanthines |
DE1545689C2 (de) | 1964-09-05 | 1982-07-01 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von 2-Methyl-3-carbäthoxy-5,6-dihydropyran |
US3422107A (en) | 1964-09-05 | 1969-01-14 | Albert Ag Chem Werke | Certain oxoalkyldimethylxanthines and a process for the preparation thereof |
US3737433A (en) | 1964-09-05 | 1973-06-05 | Albert Ag Chem Werke | Certain oxoalkyldimethylxanthines |
DE1233405B (de) | 1964-09-05 | 1967-02-02 | Albert Ag Chem Werke | Verfahren zur Herstellung von 7-(Oxoalkyl)-1, 3-dimethylxanthinen |
DE1810705C3 (de) * | 1968-11-25 | 1980-11-27 | Hoechst Ag, 6000 Frankfurt | Stabilisierung von Vitaminen |
US3864469A (en) * | 1967-12-16 | 1975-02-04 | Hoechst Ag | Xanthines in pharmaceutical preparations and for stabilization of vitamins |
DE1911279A1 (de) * | 1969-03-05 | 1970-11-12 | Eckert Dr Theodor | Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen |
-
1973
- 1973-06-16 DE DE2330742A patent/DE2330742C2/de not_active Expired
-
1974
- 1974-01-01 AR AR254209A patent/AR208179A1/es active
- 1974-06-11 NO NO742121A patent/NO140300C/no unknown
- 1974-06-11 ES ES427171A patent/ES427171A1/es not_active Expired
- 1974-06-12 ZA ZA00743760A patent/ZA743760B/xx unknown
- 1974-06-13 NL NLAANVRAGE7407890,A patent/NL182806C/xx not_active IP Right Cessation
- 1974-06-14 FR FR7420679A patent/FR2233065B1/fr not_active Expired
- 1974-06-14 SE SE7407913A patent/SE423631B/xx not_active IP Right Cessation
- 1974-06-14 CH CH748211A patent/CH608807A5/xx not_active IP Right Cessation
- 1974-06-14 CH CH123978A patent/CH612969A5/xx not_active IP Right Cessation
- 1974-06-14 FI FI1819/74A patent/FI58920C/fi active
- 1974-06-14 AT AT491874A patent/AT334388B/de not_active IP Right Cessation
- 1974-06-14 BE BE145417A patent/BE816332A/xx not_active IP Right Cessation
- 1974-06-14 IE IE1258/74A patent/IE39898B1/xx unknown
- 1974-06-14 GB GB2655574A patent/GB1470220A/en not_active Expired
- 1974-06-14 JP JP49067265A patent/JPS5233120B2/ja not_active Expired
- 1974-06-14 DK DK321574A patent/DK145676C/da active
-
1975
- 1975-08-22 AR AR260113A patent/AR209320A1/es active
- 1975-08-22 AR AR260112A patent/AR209319A1/es active
-
1979
- 1979-04-23 US US06/032,536 patent/US4289776A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IE39898L (en) | 1974-12-16 |
AR208179A1 (es) | 1976-12-09 |
AT334388B (de) | 1976-01-10 |
FI58920C (fi) | 1981-05-11 |
GB1470220A (en) | 1977-04-14 |
NL182806B (nl) | 1987-12-16 |
CH612969A5 (de) | 1979-08-31 |
NO140300B (no) | 1979-04-30 |
CH608807A5 (de) | 1979-01-31 |
IE39898B1 (en) | 1979-01-31 |
SE7407913L (de) | 1974-12-17 |
FR2233065B1 (de) | 1978-07-21 |
FI58920B (fi) | 1981-01-30 |
DK145676B (da) | 1983-01-24 |
NO140300C (no) | 1979-08-08 |
JPS5047992A (de) | 1975-04-28 |
ZA743760B (en) | 1975-06-25 |
DK321574A (de) | 1975-02-10 |
ES427171A1 (es) | 1976-07-16 |
NL7407890A (de) | 1974-12-18 |
AR209320A1 (es) | 1977-04-15 |
DE2330742A1 (de) | 1975-01-09 |
NO742121L (de) | 1975-01-13 |
US4289776A (en) | 1981-09-15 |
JPS5233120B2 (de) | 1977-08-26 |
FI181974A (de) | 1974-12-17 |
BE816332A (fr) | 1974-12-16 |
SE423631B (sv) | 1982-05-17 |
NL182806C (nl) | 1988-05-16 |
AR209319A1 (es) | 1977-04-15 |
FR2233065A1 (de) | 1975-01-10 |
AU7014774A (en) | 1975-12-18 |
DK145676C (da) | 1983-08-01 |
DE2330742C2 (de) | 1982-07-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AT334388B (de) | Verfahren zur herstellung von neuen 1- oder 7-(omega-1)-oxoalkyl-3,7 (oder 1,3)-dialkylxanthinen | |
AT337178B (de) | Verfahren zur herstellung von neuen 1-hydroxy- und 1-alkanoyloxy-3-alkyl-6,6a,7,8,10,10a-hexahydro-9h-dibenzo(b,d)pyran-9-onen | |
AT331258B (de) | Verfahren zur herstellung von neuen 1,2,3-oxathiazin-4-onen | |
DD112443A5 (de) | Verfahren zur herstellung von 2,2,6,6-tetramethyl-4-oxopiperidin | |
ATA575574A (de) | Verfahren zur herstellung von neuen 1,3-oxygenierten 8alfa-oestratrienen | |
AT342556B (de) | Verfahren zur herstellung von neuen 1,2,2,2-tetrafluorathylathern | |
AT339606B (de) | Verfahren zur herstellung von neuen, ketimingruppen enthaltenden prapolymeren | |
AT342557B (de) | Verfahren zur herstellung von neuen 2,2,2-trifluor-1-chlorathyl-athern | |
AT327902B (de) | Verfahren zur herstellung von neuen 3,4-dihydropyridonen | |
AT328452B (de) | Verfahren zur herstellung von neuen 1,4-dihydrochinolinen | |
AT339283B (de) | Verfahren zur herstellung von neuen 3,4-diamino-benzophenonen | |
AT328441B (de) | Verfahren zur herstellung von neuen 2,10-dichlor-12-methyl-12h-dibenzo- (d,g) (1,3)-dioxocinderivaten | |
ATA74374A (de) | Verfahren zur herstellung des neuen 1,3-bis-(beta-athylhexy)-5-amino-5-methyl-hexahydropyrimidin-pyridin-3-carboxylats | |
AT338761B (de) | Verfahren zur herstellung von 2,3,6-trimethylphenol | |
AT326837B (de) | Verfahren zur herstellung von neuen 2,2'-anhydro-1-beta-d-arabinofuranosyl-5-fluorcytosin-hydrofluorid, -hydrochlorid oder -hydrobromid | |
ATA299575A (de) | Verfahren zur herstellung von neuen 3,4-dicarboxycephalosporinen | |
ATA738875A (de) | Verfahren zur herstellung von neuen 1- oder 7-(omega-1)-oxoalkyl-3,7-(oder 1,3-)dialkylxanthinen | |
AT332001B (de) | Verfahren zur herstellung der neuen 20beta-hydroxy-9-oxo- 1,2,3,4,10,19 -hexanor-5,9-seco-pregnan-5-saure | |
ATA738975A (de) | Verfahren zur herstellung von neuen 1- oder 7-(omega-1)-oxoalkyl-3,7 (oder 1,3-)-dialkylxanthinen | |
AT327950B (de) | Verfahren zur herstellung von neuen 1,2-oxaphospholanen | |
AT338423B (de) | Verfahren zur herstellung von neuen 1,2,4-dithiaaz-3-enen | |
ATA868776A (de) | Verfahren zur herstellung von neuen 1,3-oxygenierten 8alfa-oestratrienen | |
AT332411B (de) | Verfahren zur herstellung von neuen 1,4-bis- (1'-alkyl-5'- nitroimidazolyl -2'- methylen-imino) -piperazinen | |
AT342066B (de) | Verfahren zur herstellung von neuen 2-phenyl-4h-3,1-benzoxazinen | |
AT341685B (de) | Verfahren zur herstellung von neuen 3',3''-didehydro- (cardenolid-3-tridigitoxosiden) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELA | Expired due to lapse of time |