DK156642C - Analogifremgangsmaade til fremstilling af napthalenderivater - Google Patents

Analogifremgangsmaade til fremstilling af napthalenderivater

Info

Publication number
DK156642C
DK156642C DK477674A DK477674A DK156642C DK 156642 C DK156642 C DK 156642C DK 477674 A DK477674 A DK 477674A DK 477674 A DK477674 A DK 477674A DK 156642 C DK156642 C DK 156642C
Authority
DK
Denmark
Prior art keywords
napthalend
derivatives
preparation
analogy procedure
analogy
Prior art date
Application number
DK477674A
Other languages
English (en)
Other versions
DK156642B (da
DK477674A (da
Inventor
Anthony William Lake
Carl John Rose
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of DK477674A publication Critical patent/DK477674A/da
Priority to DK236080A priority Critical patent/DK236080A/da
Priority to DK119384A priority patent/DK156562C/da
Publication of DK156642B publication Critical patent/DK156642B/da
Application granted granted Critical
Publication of DK156642C publication Critical patent/DK156642C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/26—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydration of carbon-to-carbon triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK477674A 1973-09-11 1974-09-10 Analogifremgangsmaade til fremstilling af napthalenderivater DK156642C (da)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DK236080A DK236080A (da) 1973-09-11 1980-05-30 Analogifremgangsmaade til fremstilling af 4-(6-methoxy-2-naphthyl) butan-2-on.
DK119384A DK156562C (da) 1973-09-11 1984-02-28 Naphthalenderivater til anvendelse som mellemprodukter ved fremstilling af farmaceutisk aktive naphthalenderivater

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4255073A GB1474377A (en) 1973-09-11 1973-09-11 Naphthalene derivatives
GB4255073 1973-09-11

Publications (3)

Publication Number Publication Date
DK477674A DK477674A (da) 1975-05-12
DK156642B DK156642B (da) 1989-09-18
DK156642C true DK156642C (da) 1990-01-29

Family

ID=10424914

Family Applications (1)

Application Number Title Priority Date Filing Date
DK477674A DK156642C (da) 1973-09-11 1974-09-10 Analogifremgangsmaade til fremstilling af napthalenderivater

Country Status (15)

Country Link
JP (4) JPS5920655B2 (da)
BE (1) BE819794A (da)
CH (8) CH603524A5 (da)
CY (2) CY1082A (da)
DE (2) DE2463219C2 (da)
DK (1) DK156642C (da)
FR (1) FR2242972B1 (da)
GB (1) GB1474377A (da)
HK (2) HK56180A (da)
IE (1) IE40001B1 (da)
KE (2) KE3081A (da)
MY (2) MY8100198A (da)
NL (1) NL175812C (da)
SE (2) SE420598B (da)
ZA (1) ZA745441B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL52006A0 (en) * 1976-05-13 1977-07-31 Beecham Group Ltd Novel nephthalene derivatives their preparation and pharmaceutical compositions containing them
GB2014993B (en) * 1977-11-03 1982-05-12 Beecham Group Ltd Chemical compounds
EP0003074B1 (en) * 1978-01-07 1981-04-15 Beecham Group Plc Process for the preparation of 4-(6-methoxy-2-naphthyl)butan-2-one and 2-acetyl-3-(6-methoxy-2-naphthyl) propenoic acid esters
CA1142965A (en) * 1979-06-08 1983-03-15 Alexander C. Goudie Substituted decalins, their preparation and use
GB8416638D0 (en) * 1984-06-29 1984-08-01 Beecham Group Plc Topical treatment and composition
GB8607119D0 (en) * 1986-03-21 1986-04-30 Beecham Group Plc Process
EP0477098B1 (en) * 1990-09-18 1996-06-26 Fujitsu Limited Cursor displacement control device for a computer display
GB9108128D0 (en) * 1991-04-15 1991-06-05 Zambeletti Spa L Novel formulation
GB9201857D0 (en) 1992-01-29 1992-03-18 Smithkline Beecham Plc Novel compound
GB9222849D0 (en) * 1992-10-31 1992-12-16 Smithkline Beecham Plc Novel use of pharmaceutical compositions
WO1997032837A1 (fr) * 1996-03-06 1997-09-12 Sumitomo Pharmaceuticals Co., Ltd. Derives estrogenes non steroidiens
US5861538A (en) * 1997-08-04 1999-01-19 Albemarle Corporation Production of alkoxynaphthyl-substituted ketones from naphthaldehydes
AU2003229142A1 (en) * 2002-06-07 2003-12-22 Cortical Pty Ltd Naphthalene derivatives which inhibit the cytokine or biological activity of macrophage inhibitory factor (MIF)
EP2123621A1 (de) 2008-05-20 2009-11-25 Bayer Schering Pharma Aktiengesellschaft Neue {F-18}-markierte L-Glutaminsäure- und L-Glutaminderivate (I), ihre Verwendung sowie Verfahren zu ihrer Herstellung
EP2123619A1 (de) 2008-05-20 2009-11-25 Bayer Schering Pharma AG Neue [F-18]-Markierte L-Glutaminsäure-und L-Glutaminderivate (II), ihre Verwendung sowie Verfahren zu ihrer Herstellung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO125971B (da) * 1969-05-22 1972-12-04 Syntex Corp
BR6915468D0 (pt) * 1969-10-09 1973-03-13 Syntex Corp Processo para a preparacao de d 2-(6-substituido-2-naftil)-propanal

Also Published As

Publication number Publication date
IE40001B1 (en) 1979-02-14
CH603525A5 (da) 1978-08-15
ZA745441B (en) 1975-08-27
MY8100198A (en) 1981-12-31
CH603524A5 (da) 1978-08-15
SE7907064L (sv) 1979-08-23
BE819794A (fr) 1975-03-11
JPS5890526A (ja) 1983-05-30
DK156642B (da) 1989-09-18
DE2442305A1 (de) 1975-03-13
FR2242972A1 (da) 1975-04-04
AU7313674A (en) 1976-03-11
MY8100197A (en) 1981-12-31
DK477674A (da) 1975-05-12
SE7411261L (da) 1975-03-12
JPS605580B2 (ja) 1985-02-12
IE40001L (en) 1975-03-11
CH599090A5 (da) 1978-05-12
JPS5920655B2 (ja) 1984-05-15
KE3082A (en) 1980-10-03
JPS5053359A (da) 1975-05-12
CY1083A (en) 1980-12-27
CH603523A5 (da) 1978-08-15
SE7907064A0 (sv) 1979-08-23
HK56280A (en) 1980-10-10
CY1082A (en) 1980-12-27
CH603527A5 (da) 1978-08-15
DE2463219C2 (da) 1988-02-04
NL175812B (nl) 1984-08-01
JPS5896036A (ja) 1983-06-07
NL7412060A (nl) 1975-03-13
KE3081A (en) 1980-10-03
JPS5921850B2 (ja) 1984-05-22
GB1474377A (en) 1977-05-25
JPS6033818B2 (ja) 1985-08-05
CH613932A5 (da) 1979-10-31
CH603543A5 (da) 1978-08-31
JPS58113142A (ja) 1983-07-05
CH603526A5 (da) 1978-08-15
NL175812C (nl) 1985-01-02
SE420598B (sv) 1981-10-19
DE2442305C2 (de) 1986-04-03
HK56180A (en) 1980-10-10
FR2242972B1 (da) 1978-07-21

Similar Documents

Publication Publication Date Title
DK145676C (da) Analogifremgangsmaade til fremstilling af oxoalkyldialkylxanthiner
DK283175A (da) Fremgangsmade til fremstilling af benzocycloamid-derivater
DK239075A (da) Fremgangsmade til fremstilling af iodbenzenderivater
DK155043C (da) Analogifremgangsmaade til fremstilling af polyenforbindelser
DK156642C (da) Analogifremgangsmaade til fremstilling af napthalenderivater
DK143902C (da) Analogifremgangsmaade til fremstilling af 8alfa-ergolin-i-derivater
DK147004C (da) Analogifremgangsmaade til fremstilling af oxygenerede alkylxanthinderivater
DK145878C (da) Analogifremgangsmaade til fremstilling af alkylthiocyclopentanderivater
DK140985C (da) Analogifremgangsmaade til fremstilling af indolderivater
DK146539C (da) Analogifremgangsmaade til fremstilling af 7alfa-methoxycephalosporin-derivater
DK143804C (da) Analogifremgangsmaade til fremstilling af ergopeptinderivater
DK211075A (da) Fremgangsmade til fremstilling af abietamidderivater
DK145696C (da) Fremgangsmaade til fremstilling af 2-arylamino-2-imidazolin-derivater
DK376975A (da) Fremgangsmade til fremstilling af abietamidderivater
DK144270C (da) Analogifremgangsmaade til fremstilling af n-carbamoyl-2-phenylethensulfonamider
DK271975A (da) Fremgangsmade til fremstilling af acylderivater
DK136249C (da) Analogifremgangsmade til fremstilling af xanthenderivater
DK198175A (da) Fremgangsmade til fremstilling af indolkinolizidinderivater
DK238090D0 (da) Fremgangsmaade til fremstilling af benzocycloheptathiophenderivater
SE417967B (sv) Analogiforfarande for framstellning av reserpinderivat
DK143939C (da) Fremgangsmaade til fremstilling af prostaglandin-fbeta-derivater
DK507275A (da) Fremgangsmade til fremstilling af aminomethylarylmethylpenicillin-derivater
DK515875A (da) Fremgangsmade til fremstilling af 7alfa-alkoxycephalosporin-derivater
DK143027C (da) Analogifremgangsmaade til fremstilling af isoxazolderivater
DK144065C (da) Analogifremgangsmaade til fremstilling af thiazolderivater

Legal Events

Date Code Title Description
PUP Patent expired