DK143604C - 18-methyl-4,15-oestradiener til anvendelse i svangerskabsforebyggende midler - Google Patents

18-methyl-4,15-oestradiener til anvendelse i svangerskabsforebyggende midler

Info

Publication number
DK143604C
DK143604C DK77678A DK77678A DK143604C DK 143604 C DK143604 C DK 143604C DK 77678 A DK77678 A DK 77678A DK 77678 A DK77678 A DK 77678A DK 143604 C DK143604 C DK 143604C
Authority
DK
Denmark
Prior art keywords
oestradients
methyl
pregnancy prevention
pregnancy
prevention
Prior art date
Application number
DK77678A
Other languages
English (en)
Other versions
DK77678A (da
DK143604B (da
Inventor
H Hofmeister
R Wiechert
K Annen
H Laurent
H Steinbeck
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19752546062 external-priority patent/DE2546062A1/de
Priority claimed from DE19762636405 external-priority patent/DE2636405C2/de
Priority claimed from DE19762636407 external-priority patent/DE2636407A1/de
Priority claimed from DE19762636404 external-priority patent/DE2636404C2/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK77678A publication Critical patent/DK77678A/da
Publication of DK143604B publication Critical patent/DK143604B/da
Application granted granted Critical
Publication of DK143604C publication Critical patent/DK143604C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK77678A 1975-10-10 1978-02-21 18-methyl-4,15-oestradiener til anvendelse i svangerskabsforebyggende midler DK143604C (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
DE2546062 1975-10-10
DE19752546062 DE2546062A1 (de) 1975-10-10 1975-10-10 Delta hoch 15 -steroide
DE2636405 1976-08-12
DE19762636405 DE2636405C2 (de) 1976-08-12 1976-08-12 Δ↑1↑↑5↑-17α-Chloräthinyl- und -Propinylsteroide der Östranreihe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Präparate
DE19762636407 DE2636407A1 (de) 1976-08-12 1976-08-12 Delta hoch 15 -steroide
DE19762636404 DE2636404C2 (de) 1976-08-12 1976-08-12 Δ↑1↑↑5↑-17α-Äthinylsteroide der Östranreihe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Präparate
DE2636404 1976-08-12
DE2636407 1976-08-12
DK454376A DK138749C (da) 1975-10-10 1976-10-08 Analogifremgangsmaade til fremstilling af 18-methyl-4,15-oestradiener
DK454376 1976-10-08

Publications (3)

Publication Number Publication Date
DK77678A DK77678A (da) 1978-02-21
DK143604B DK143604B (da) 1981-09-14
DK143604C true DK143604C (da) 1982-02-22

Family

ID=27432034

Family Applications (2)

Application Number Title Priority Date Filing Date
DK454376A DK138749C (da) 1975-10-10 1976-10-08 Analogifremgangsmaade til fremstilling af 18-methyl-4,15-oestradiener
DK77678A DK143604C (da) 1975-10-10 1978-02-21 18-methyl-4,15-oestradiener til anvendelse i svangerskabsforebyggende midler

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK454376A DK138749C (da) 1975-10-10 1976-10-08 Analogifremgangsmaade til fremstilling af 18-methyl-4,15-oestradiener

Country Status (33)

Country Link
US (1) US4081537A (da)
JP (1) JPS5246060A (da)
AT (1) AT358199B (da)
AU (1) AU500942B2 (da)
BE (1) BE847090A (da)
BG (1) BG34187A3 (da)
CA (1) CA1069885A (da)
CH (2) CH630392A5 (da)
CY (1) CY1119A (da)
DD (1) DD126925B3 (da)
DK (2) DK138749C (da)
ES (1) ES452226A1 (da)
FI (1) FI56389C (da)
FR (1) FR2326927A1 (da)
GB (1) GB1569135A (da)
GR (1) GR60835B (da)
HK (1) HK41381A (da)
HU (1) HU176164B (da)
IE (1) IE43742B1 (da)
IT (1) IT1070580B (da)
KE (1) KE3153A (da)
LU (2) LU75961A1 (da)
MX (1) MX3847E (da)
MY (1) MY8200128A (da)
NL (2) NL187116C (da)
NO (2) NO144490C (da)
NZ (1) NZ182237A (da)
PH (1) PH12941A (da)
PL (1) PL103002B1 (da)
PT (1) PT65697B (da)
SE (2) SE415839B (da)
SU (1) SU671733A3 (da)
YU (1) YU39668B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3178784A (en) * 1963-03-27 1965-04-20 Krauthamer Charles Magnetic pocket pencil holder
DE3002746A1 (de) * 1980-01-23 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin 1-hydroxysteroide, verfahren zu ihrer herstellung und pharmazeutische praeparate, die diese verbindungen enthalten
DE3005374A1 (de) * 1980-02-11 1981-08-20 Schering Ag Berlin Und Bergkamen, 1000 Berlin 3-desoxy-delta hoch 15 -steroide, verfahren zu ihrer herstellung sowie diese enthaltende pharmazeutische praeparate
DE3042529A1 (de) * 1980-11-07 1982-06-24 Schering Ag, 1000 Berlin Und 4619 Bergkamen 11-methylen- (delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)5(pfeil hoch) -steroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3214690A1 (de) * 1982-04-16 1983-10-27 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-chlor-(delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)5(pfeil hoch)-steroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
CN1008820B (zh) * 1985-05-10 1990-07-18 施林工业产权保护股份公司 17α-乙炔基-17β-羟基-18-甲基-4，15-雌甾二烯-3-酮的制备方法
CA1317283C (en) * 1986-11-05 1993-05-04 Douglas Alan Livingston Steroidal 17–-silyl ethers and process to corticoids and progesterones
DE3710728A1 (de) * 1987-03-31 1988-10-13 Schering Ag Verfahren zur herstellung von 17(alpha)-ethinyl-17ss-hydroxy-18-methyl-4,15-estradien-3-on und die neuen zwischenprodukte fuer dieses verfahren
CA2091883A1 (en) * 1990-10-29 1992-04-30 Robert M. Gale Transdermal contraceptive formulations, methods and devices
US5512292A (en) * 1990-10-29 1996-04-30 Alza Corporation Transdermal contraceptive formulations methods and devices
CA2100514C (en) * 1992-07-29 2005-03-29 Johannes A. M. Hamersma 17-spiromethylene steroids
DE4329242A1 (de) * 1993-08-26 1995-03-02 Schering Ag Mittel zur transdermalen Applikation enthaltend Gestodenester
US5567830A (en) * 1994-02-14 1996-10-22 Cocensys, Inc. Process for synthesis of acetylenic carbinols
IT1271004B (it) * 1994-09-09 1997-05-26 Ind Chimica Srl Processo per la preparazione del gestodene
US20050143360A1 (en) * 2001-02-02 2005-06-30 Joel Krasnow Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dismenorrhea
UA89766C2 (en) 2003-12-12 2010-03-10 Байер Шеринг Фарма Акциенгезельшафт Transdermal delivery system of gestodene
EP2354150A1 (en) 2010-02-09 2011-08-10 Laboratoire Theramex Process for the preparation of gestodene
ME02618B (me) 2010-09-06 2017-06-20 Bayer Ip Gmbh Transdermalni flasteri sa malom dozom i velikim oslobađanjem leka
CN105237605B (zh) * 2014-07-11 2019-01-25 上海迪赛诺生物医药有限公司 一种用于合成孕二烯酮的中间体及其制备方法和应用
CN115850359B (zh) * 2022-12-14 2024-06-11 梯尔希（南京）药物研发有限公司 一种孕二烯酮杂质i的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3433785A (en) * 1966-07-11 1969-03-18 Sterling Drug Inc 15,16-disubstituted aromatic steroids,intermediates and processes
US3475463A (en) * 1966-07-11 1969-10-28 Sterling Drug Inc 15,16-unsaturated 19-norsteroids and their preparation
DE2439082A1 (de) * 1974-08-12 1976-02-26 Schering Ag 17 alpha-hydroxy-1,3,5(10),15-oestratetraene und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
CH626636A5 (en) 1981-11-30
HK41381A (en) 1981-08-28
PT65697B (pt) 1978-04-17
NZ182237A (en) 1978-09-20
NL187116B (nl) 1991-01-02
KE3153A (en) 1981-09-18
MX3847E (es) 1981-08-18
ES452226A1 (es) 1977-11-01
DD126925B3 (de) 1990-06-06
JPS6119640B2 (da) 1986-05-17
PH12941A (en) 1979-10-18
FI56389B (fi) 1979-09-28
FR2326927A1 (fr) 1977-05-06
LU75961A1 (da) 1977-05-09
AT358199B (de) 1980-08-25
DK77678A (da) 1978-02-21
DK138749C (da) 1979-04-02
LU88290I2 (de) 1994-05-04
DD126925A5 (da) 1977-08-24
SE415839B (sv) 1980-11-03
AU500942B2 (en) 1979-06-07
DK138749B (da) 1978-10-23
CY1119A (en) 1981-12-04
MY8200128A (en) 1982-12-31
JPS5246060A (en) 1977-04-12
ATA748776A (de) 1980-01-15
NO144490C (no) 1981-09-09
GB1569135A (en) 1980-06-11
NO801013L (no) 1977-04-13
FR2326927B1 (da) 1979-09-28
GR60835B (en) 1978-08-31
NO763434L (da) 1977-04-13
DK143604B (da) 1981-09-14
NL187116C (nl) 1991-06-03
SE7611145L (sv) 1977-04-11
PT65697A (en) 1976-11-01
CH630392A5 (de) 1982-06-15
IE43742L (en) 1977-04-10
BG34187A3 (en) 1983-07-15
PL103002B1 (pl) 1979-05-31
NO144967B (no) 1981-09-07
BE847090A (fr) 1977-04-08
YU245276A (en) 1982-08-31
SU671733A3 (ru) 1979-06-30
CA1069885A (en) 1980-01-15
AU1851076A (en) 1978-04-13
US4081537A (en) 1978-03-28
IT1070580B (it) 1985-03-29
NL930071I2 (nl) 1994-02-16
FI56389C (fi) 1980-01-10
FI762876A (da) 1977-04-11
SE7907224L (sv) 1979-08-30
DK454376A (da) 1977-04-11
SE428929B (sv) 1983-08-01
NL930071I1 (nl) 1993-09-01
NL7611073A (nl) 1977-04-13
NO144967C (no) 1981-12-16
IE43742B1 (en) 1981-05-20
YU39668B (en) 1985-03-20
HU176164B (en) 1980-12-28
NO144490B (no) 1981-06-01

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Legal Events

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PUP Patent expired