DK142869B - Analogifremgangsmåde til fremstilling af 2,6-dialkyl-4-phenyl-1,4-dihydropyridin-3-carboxylsyre-aminoalkylester-forbindelser. - Google Patents

Analogifremgangsmåde til fremstilling af 2,6-dialkyl-4-phenyl-1,4-dihydropyridin-3-carboxylsyre-aminoalkylester-forbindelser. Download PDF

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Publication number
DK142869B
DK142869B DK87774AA DK87774A DK142869B DK 142869 B DK142869 B DK 142869B DK 87774A A DK87774A A DK 87774AA DK 87774 A DK87774 A DK 87774A DK 142869 B DK142869 B DK 142869B
Authority
DK
Denmark
Prior art keywords
formula
compound
defined above
ester
acid
Prior art date
Application number
DK87774AA
Other languages
Danish (da)
English (en)
Other versions
DK142869C (fi
Inventor
Toichi Takenaka
Masuo Murakami
Kozo Takahashi
Masaru Iwanami
Masaharu Fujimoto
Tadao Shibanuma
Ryutaro Kawai
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP48020423A external-priority patent/JPS5930704B2/ja
Priority claimed from JP2556673A external-priority patent/JPS49109384A/ja
Priority claimed from JP4482173A external-priority patent/JPS5714348B2/ja
Priority claimed from JP5230773A external-priority patent/JPS49135976A/ja
Priority claimed from JP5493973A external-priority patent/JPS504082A/ja
Priority claimed from JP8327673A external-priority patent/JPS5720950B2/ja
Priority claimed from JP13407073A external-priority patent/JPS5084577A/ja
Priority claimed from JP13406973A external-priority patent/JPS5545075B2/ja
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of DK142869B publication Critical patent/DK142869B/da
Application granted granted Critical
Publication of DK142869C publication Critical patent/DK142869C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK87774AA 1973-02-20 1974-02-19 Analogifremgangsmåde til fremstilling af 2,6-dialkyl-4-phenyl-1,4-dihydropyridin-3-carboxylsyre-aminoalkylester-forbindelser. DK142869B (da)

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
JP48020423A JPS5930704B2 (ja) 1973-02-20 1973-02-20 新規１，４−ジヒドロピリジン誘導体の製法
JP2042373 1973-02-20
JP2556673 1973-03-03
JP2556673A JPS49109384A (fi) 1973-03-03 1973-03-03
JP4482173 1973-04-20
JP4482173A JPS5714348B2 (fi) 1973-04-20 1973-04-20
JP5230773A JPS49135976A (fi) 1973-05-11 1973-05-11
JP5230773 1973-05-11
JP5493973A JPS504082A (fi) 1973-05-17 1973-05-17
JP5493973 1973-05-17
JP8327673A JPS5720950B2 (fi) 1973-07-24 1973-07-24
JP8327673 1973-07-24
JP13407073A JPS5084577A (fi) 1973-11-29 1973-11-29
JP13407073 1973-11-29
JP13406973 1973-11-29
JP13406973A JPS5545075B2 (fi) 1973-11-29 1973-11-29

Publications (2)

Publication Number Publication Date
DK142869B true DK142869B (da) 1981-02-16
DK142869C DK142869C (fi) 1981-09-28

Family

ID=27571887

Family Applications (1)

Application Number Title Priority Date Filing Date
DK87774AA DK142869B (da) 1973-02-20 1974-02-19 Analogifremgangsmåde til fremstilling af 2,6-dialkyl-4-phenyl-1,4-dihydropyridin-3-carboxylsyre-aminoalkylester-forbindelser.

Country Status (8)

Country Link
CA (1) CA1023746A (fi)
CH (1) CH605755A5 (fi)
DE (1) DE2407115C3 (fi)
DK (1) DK142869B (fi)
FI (1) FI58772C (fi)
GB (1) GB1455502A (fi)
NL (2) NL176559C (fi)
NO (1) NO143846C (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK152285B (da) * 1975-07-02 1988-02-15 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE2815578C2 (de) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen Neue pharmazeutische Verwendung von Nimodipin
IT1097538B (it) * 1978-07-17 1985-08-31 Medea Res Srl Processo per la preparazione del 2,6-dimetil-4-3(3-nitrofenil)-3-metossicarbonil-1,4-didropiridin-5-carbossilati di 2(n-benzil-n-metilammino)
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
JPS5762257A (en) * 1980-10-03 1982-04-15 Yoshitomi Pharmaceut Ind Ltd 1,4-dihydropyridine-3,5-dicarboxylic acid ester or its salt
JPS57200386A (en) * 1981-06-04 1982-12-08 Yoshitomi Pharmaceut Ind Ltd Novel 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its salts
WO1983003249A1 (en) * 1982-03-17 1983-09-29 Yoshitomi Pharmaceutical 1,4-dihydropyridine-3,5-dicarboxylate derivatives
EP0094159B1 (en) * 1982-05-10 1990-03-14 Takeda Chemical Industries, Ltd. Dihydropyridine derivatives, their production and use
DE3577184D1 (de) * 1984-01-13 1990-05-23 Yamanouchi Pharma Co Ltd Arzneimittel fuer die behandlung und verhuetung von leberschaedigungen.
AT388375B (de) * 1984-04-11 1989-06-12 Bristol Myers Co Verfahren zur herstellung von neuen dihydropyridincarbonsaeureamiden und -estern
JPS6289662A (ja) * 1985-06-14 1987-04-24 Sankyo Co Ltd １，４−ジヒドロピリジン誘導体
DE3531498A1 (de) * 1985-09-04 1987-03-05 Bayer Ag Dihydropyridin-2-hydroxyamine, verfahren zur herstellung und ihre verwendung in arzneimitteln
DE3621104A1 (de) * 1986-06-24 1988-01-07 Heumann Pharma Gmbh & Co 1,4-dihydropyridinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4772596A (en) * 1986-10-09 1988-09-20 Sankyo Company Limited Dihydropyridine derivatives, their preparation and their use
YU45837B (sh) * 1988-01-18 1992-07-20 LEK TOVARNA FARMACEVTSKIH IN KEMIČKIH IZDELKOV d.d. Postopek za pripravo novega inkluzijskega kompleksa nikardipina oz. njegovega hidroklorida z beta-ciklodekstrinom
NL9001752A (nl) * 1990-08-02 1992-03-02 Cedona Pharm Bv Nieuwe 1,4-dihydropyridinederivaten.
US6350766B1 (en) 1997-04-25 2002-02-26 Ajinomoto Co., Inc. Dihydropyridine derivative
ES2332168B1 (es) * 2008-04-30 2010-10-27 Consejo Superior De Investigaciones Cientificas (Csic) (75%) Forma pseudopolimorfica de hidrocloruro de nicardipina, procedimiento para su preparacion y formulacion que la contiene.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK152285B (da) * 1975-07-02 1988-02-15 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater

Also Published As

Publication number Publication date
NO143846C (no) 1981-04-29
DE2407115B2 (de) 1979-08-09
CH605755A5 (fi) 1978-10-13
NO143846B (no) 1981-01-12
NL176559C (nl) 1985-05-01
AU6565574A (en) 1975-08-21
NO740543L (no) 1974-08-21
NL930023I2 (nl) 1997-08-01
CA1023746A (en) 1978-01-03
NL176559B (nl) 1984-12-03
NL930023I1 (nl) 1993-05-17
FI58772C (fi) 1981-04-10
DK142869C (fi) 1981-09-28
DE2407115A1 (de) 1974-10-10
DE2407115C3 (de) 1980-05-08
FI58772B (fi) 1980-12-31
GB1455502A (en) 1976-11-10
NL7402277A (fi) 1974-08-22

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PUP Patent expired