CA1023746A - 2,6-dimethyl-4-phenyl-1,4-dihydropyridines - Google Patents

2,6-dimethyl-4-phenyl-1,4-dihydropyridines

Info

Publication number
CA1023746A
CA1023746A CA192,552A CA192552A CA1023746A CA 1023746 A CA1023746 A CA 1023746A CA 192552 A CA192552 A CA 192552A CA 1023746 A CA1023746 A CA 1023746A
Authority
CA
Canada
Prior art keywords
dihydropyridines
dimethyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA192,552A
Other languages
English (en)
Inventor
Kozo Takahashi
Masuo Murakami
Masaru Iwanami
Masaharu Fujimoto
Tadao Shibanuma
Ryutaro Kawai
Toichi Takenaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP48020423A external-priority patent/JPS5930704B2/ja
Priority claimed from JP2556673A external-priority patent/JPS49109384A/ja
Priority claimed from JP4482173A external-priority patent/JPS5714348B2/ja
Priority claimed from JP5230773A external-priority patent/JPS49135976A/ja
Priority claimed from JP5493973A external-priority patent/JPS504082A/ja
Priority claimed from JP8327673A external-priority patent/JPS5720950B2/ja
Priority claimed from JP13406973A external-priority patent/JPS5545075B2/ja
Priority claimed from JP13407073A external-priority patent/JPS5084577A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Priority to CA284,380A priority Critical patent/CA1029021A/en
Priority to CA284,381A priority patent/CA1029022A/en
Publication of CA1023746A publication Critical patent/CA1023746A/en
Application granted granted Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA192,552A 1973-02-20 1974-02-14 2,6-dimethyl-4-phenyl-1,4-dihydropyridines Expired CA1023746A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA284,381A CA1029022A (en) 1973-07-24 1977-08-09 Process of producing novel 1,4-dihydro-pyridine derivatives
CA284,380A CA1029021A (en) 1973-05-11 1977-08-09 Process of producing novel 1,4-dihydro-pyridine derivatives

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP48020423A JPS5930704B2 (ja) 1973-02-20 1973-02-20 新規１，４−ジヒドロピリジン誘導体の製法
JP2556673A JPS49109384A (fi) 1973-03-03 1973-03-03
JP4482173A JPS5714348B2 (fi) 1973-04-20 1973-04-20
JP5230773A JPS49135976A (fi) 1973-05-11 1973-05-11
JP5493973A JPS504082A (fi) 1973-05-17 1973-05-17
JP8327673A JPS5720950B2 (fi) 1973-07-24 1973-07-24
JP13406973A JPS5545075B2 (fi) 1973-11-29 1973-11-29
JP13407073A JPS5084577A (fi) 1973-11-29 1973-11-29

Publications (1)

Publication Number Publication Date
CA1023746A true CA1023746A (en) 1978-01-03

Family

ID=27571887

Family Applications (1)

Application Number Title Priority Date Filing Date
CA192,552A Expired CA1023746A (en) 1973-02-20 1974-02-14 2,6-dimethyl-4-phenyl-1,4-dihydropyridines

Country Status (8)

Country Link
CA (1) CA1023746A (fi)
CH (1) CH605755A5 (fi)
DE (1) DE2407115C3 (fi)
DK (1) DK142869B (fi)
FI (1) FI58772C (fi)
GB (1) GB1455502A (fi)
NL (2) NL176559C (fi)
NO (1) NO143846C (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK152285C (da) * 1975-07-02 1988-10-10 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE2815578C2 (de) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen Neue pharmazeutische Verwendung von Nimodipin
IT1097538B (it) * 1978-07-17 1985-08-31 Medea Res Srl Processo per la preparazione del 2,6-dimetil-4-3(3-nitrofenil)-3-metossicarbonil-1,4-didropiridin-5-carbossilati di 2(n-benzil-n-metilammino)
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
JPS5762257A (en) * 1980-10-03 1982-04-15 Yoshitomi Pharmaceut Ind Ltd 1,4-dihydropyridine-3,5-dicarboxylic acid ester or its salt
JPS57200386A (en) * 1981-06-04 1982-12-08 Yoshitomi Pharmaceut Ind Ltd Novel 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its salts
WO1983003249A1 (en) * 1982-03-17 1983-09-29 Yoshitomi Pharmaceutical 1,4-dihydropyridine-3,5-dicarboxylate derivatives
EP0094159B1 (en) * 1982-05-10 1990-03-14 Takeda Chemical Industries, Ltd. Dihydropyridine derivatives, their production and use
DE3577184D1 (de) * 1984-01-13 1990-05-23 Yamanouchi Pharma Co Ltd Arzneimittel fuer die behandlung und verhuetung von leberschaedigungen.
AT388375B (de) * 1984-04-11 1989-06-12 Bristol Myers Co Verfahren zur herstellung von neuen dihydropyridincarbonsaeureamiden und -estern
JPS6289662A (ja) * 1985-06-14 1987-04-24 Sankyo Co Ltd １，４−ジヒドロピリジン誘導体
DE3531498A1 (de) * 1985-09-04 1987-03-05 Bayer Ag Dihydropyridin-2-hydroxyamine, verfahren zur herstellung und ihre verwendung in arzneimitteln
DE3621104A1 (de) * 1986-06-24 1988-01-07 Heumann Pharma Gmbh & Co 1,4-dihydropyridinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4772596A (en) * 1986-10-09 1988-09-20 Sankyo Company Limited Dihydropyridine derivatives, their preparation and their use
YU45837B (sh) * 1988-01-18 1992-07-20 LEK TOVARNA FARMACEVTSKIH IN KEMIČKIH IZDELKOV d.d. Postopek za pripravo novega inkluzijskega kompleksa nikardipina oz. njegovega hidroklorida z beta-ciklodekstrinom
NL9001752A (nl) * 1990-08-02 1992-03-02 Cedona Pharm Bv Nieuwe 1,4-dihydropyridinederivaten.
US6350766B1 (en) 1997-04-25 2002-02-26 Ajinomoto Co., Inc. Dihydropyridine derivative
ES2332168B1 (es) * 2008-04-30 2010-10-27 Consejo Superior De Investigaciones Cientificas (Csic) (75%) Forma pseudopolimorfica de hidrocloruro de nicardipina, procedimiento para su preparacion y formulacion que la contiene.

Also Published As

Publication number Publication date
NO143846C (no) 1981-04-29
DE2407115B2 (de) 1979-08-09
CH605755A5 (fi) 1978-10-13
NO143846B (no) 1981-01-12
NL176559C (nl) 1985-05-01
AU6565574A (en) 1975-08-21
NO740543L (no) 1974-08-21
NL930023I2 (nl) 1997-08-01
NL176559B (nl) 1984-12-03
DK142869B (da) 1981-02-16
NL930023I1 (nl) 1993-05-17
FI58772C (fi) 1981-04-10
DK142869C (fi) 1981-09-28
DE2407115A1 (de) 1974-10-10
DE2407115C3 (de) 1980-05-08
FI58772B (fi) 1980-12-31
GB1455502A (en) 1976-11-10
NL7402277A (fi) 1974-08-22

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