DK142812B - Analogifremgangsmåde til fremstilling af 3-(1,2,3,6-tetrahydro-4-pyridyl)-1-H-indolderivater eller syreadditionssalte deraf. - Google Patents
Analogifremgangsmåde til fremstilling af 3-(1,2,3,6-tetrahydro-4-pyridyl)-1-H-indolderivater eller syreadditionssalte deraf. Download PDFInfo
- Publication number
- DK142812B DK142812B DK376577AA DK376577A DK142812B DK 142812 B DK142812 B DK 142812B DK 376577A A DK376577A A DK 376577AA DK 376577 A DK376577 A DK 376577A DK 142812 B DK142812 B DK 142812B
- Authority
- DK
- Denmark
- Prior art keywords
- tetrahydro
- indole
- pyridyl
- acid
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
- C07C55/10—Succinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7625798A FR2362628A1 (fr) | 1976-08-26 | 1976-08-26 | Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments |
FR7625798 | 1976-08-26 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK376577A DK376577A (el) | 1978-02-27 |
DK142812B true DK142812B (da) | 1981-02-02 |
DK142812C DK142812C (el) | 1981-09-21 |
Family
ID=9177152
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK376577AA DK142812B (da) | 1976-08-26 | 1977-08-25 | Analogifremgangsmåde til fremstilling af 3-(1,2,3,6-tetrahydro-4-pyridyl)-1-H-indolderivater eller syreadditionssalte deraf. |
Country Status (19)
Country | Link |
---|---|
US (1) | US4196209A (el) |
JP (1) | JPS5328178A (el) |
AT (1) | AT358582B (el) |
AU (1) | AU510037B2 (el) |
BE (1) | BE858101A (el) |
CA (1) | CA1103676A (el) |
CH (2) | CH624952A5 (el) |
DE (1) | DE2738646C2 (el) |
DK (1) | DK142812B (el) |
ES (1) | ES461875A1 (el) |
FR (1) | FR2362628A1 (el) |
GB (1) | GB1556919A (el) |
HU (1) | HU172711B (el) |
IE (1) | IE45574B1 (el) |
LU (1) | LU78028A1 (el) |
NL (1) | NL7709383A (el) |
PT (1) | PT66953B (el) |
SE (1) | SE432595B (el) |
ZA (1) | ZA775134B (el) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK152048B (da) * | 1979-07-13 | 1988-01-25 | Roussel Uclaf | Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf. |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2421899A1 (fr) * | 1978-01-16 | 1979-11-02 | Roussel Uclaf | Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits |
FR2444678A2 (fr) * | 1978-12-22 | 1980-07-18 | Roussel Uclaf | Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels |
SE8004129L (sv) * | 1979-07-13 | 1981-01-14 | Roussel Uclaf | Nya tetrahydropyridin-4-yl-indolderivat samt salter derav, framstellning och anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar |
DE3035403C2 (de) | 1980-09-19 | 1982-08-26 | Rütgerswerke AG, 6000 Frankfurt | Verfahren zur Herstellung von 5-Chlorindol |
FR2510111A1 (fr) * | 1981-07-24 | 1983-01-28 | Roussel Uclaf | Nouveaux derives du piperidin-3-yl indole, leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
IE55972B1 (en) * | 1982-10-07 | 1991-03-13 | Kefalas As | Phenylindene derivatives,acid addition salts thereof,and methods of preparation |
US4548939A (en) * | 1984-10-01 | 1985-10-22 | Janssen Pharmaceutica N. V. | 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones |
IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
US4742057A (en) * | 1985-12-05 | 1988-05-03 | Fujisawa Pharmaceutical Co., Ltd. | Antiallergic thiazole compounds |
FR2608157B1 (fr) * | 1986-12-11 | 1989-09-08 | Roussel Uclaf | Nouveaux derives de l'azaspirodecane, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant et intermediaires |
GB8719167D0 (en) * | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
DK172696B1 (da) * | 1987-08-13 | 1999-05-31 | Glaxo Group Ltd | Indolderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende forbindelserne |
FR2621586B1 (fr) * | 1987-10-08 | 1990-02-02 | Roussel Uclaf | Nouveaux derives de l'azapirodecane, leur procede de preparation et leur application comme medicaments |
GB8819024D0 (en) * | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
MX19185A (es) * | 1989-01-20 | 1993-12-01 | Pfizer | Procedimiento para preparar 3-(1,2,5,6-tretrahidropiridil)-pirrolopiridinas. |
US5643784A (en) * | 1990-12-04 | 1997-07-01 | H, Lundbeck A/S | Indan derivatives |
DK36291D0 (da) * | 1991-03-01 | 1991-03-01 | Lundbeck & Co As H | Anvendelse af piperidylsubstituerede indolderivater til behandling af kognitive lidelser |
NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
US5846982A (en) * | 1996-06-14 | 1998-12-08 | Eli Lilly And Company | Inhibition of serotonin reuptake |
JP2004517081A (ja) * | 2000-11-29 | 2004-06-10 | イーライ・リリー・アンド・カンパニー | 1−(2−m−メタンスルホンアミドフェニルエチル)−4−(m−トリフルオロメチルフェニル)ピペラジンならびにその医薬的に許容しうる塩および溶媒和物 |
WO2004069828A1 (ja) * | 2003-02-04 | 2004-08-19 | Mitsubishi Pharma Corporation | ピペリジン化合物およびその医薬用途 |
JP2009515833A (ja) * | 2005-10-24 | 2009-04-16 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 3−ピペリジン−4−イル−インドールorl−1受容体モジュレーター |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2872453A (en) * | 1959-02-03 | Indole derivatives | ||
US3361759A (en) * | 1963-10-07 | 1968-01-02 | Upjohn Co | 3-(2-pyrrolidinyl)-indoles and method of preparation |
JPS4856687A (el) * | 1971-11-18 | 1973-08-09 | ||
FR2193584B1 (el) * | 1972-07-28 | 1975-08-08 | Roussel Uclaf | |
DE2322470A1 (de) * | 1973-05-04 | 1974-11-21 | Boehringer Sohn Ingelheim | Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung |
FR2258843B1 (el) * | 1974-01-30 | 1977-09-09 | Roussel Uclaf | |
IL48508A (en) * | 1974-12-09 | 1979-10-31 | Roussel Uclaf | Pharmaceutical compositions comprising piperidylindole derivatives |
FR2349331A1 (fr) * | 1976-04-30 | 1977-11-25 | Roussel Uclaf | Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments |
-
1976
- 1976-08-26 FR FR7625798A patent/FR2362628A1/fr active Granted
-
1977
- 1977-07-04 SE SE7707731A patent/SE432595B/xx not_active IP Right Cessation
- 1977-08-01 US US05/820,835 patent/US4196209A/en not_active Expired - Lifetime
- 1977-08-24 ZA ZA00775134A patent/ZA775134B/xx unknown
- 1977-08-24 PT PT66953A patent/PT66953B/pt unknown
- 1977-08-25 AU AU28213/77A patent/AU510037B2/en not_active Expired
- 1977-08-25 ES ES461875A patent/ES461875A1/es not_active Expired
- 1977-08-25 JP JP10116577A patent/JPS5328178A/ja active Granted
- 1977-08-25 BE BE180423A patent/BE858101A/xx not_active IP Right Cessation
- 1977-08-25 NL NL7709383A patent/NL7709383A/xx not_active Application Discontinuation
- 1977-08-25 CA CA285,446A patent/CA1103676A/fr not_active Expired
- 1977-08-25 LU LU78028A patent/LU78028A1/xx unknown
- 1977-08-25 DK DK376577AA patent/DK142812B/da not_active IP Right Cessation
- 1977-08-26 GB GB35882/77A patent/GB1556919A/en not_active Expired
- 1977-08-26 CH CH1046877A patent/CH624952A5/fr not_active IP Right Cessation
- 1977-08-26 AT AT619677A patent/AT358582B/de not_active IP Right Cessation
- 1977-08-26 IE IE1792/77A patent/IE45574B1/en unknown
- 1977-08-26 DE DE2738646A patent/DE2738646C2/de not_active Expired
- 1977-08-26 HU HU77RO00000938A patent/HU172711B/hu not_active IP Right Cessation
-
1981
- 1981-01-14 CH CH22781A patent/CH628344A5/fr not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK152048B (da) * | 1979-07-13 | 1988-01-25 | Roussel Uclaf | Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf. |
Also Published As
Publication number | Publication date |
---|---|
SE7707731L (sv) | 1978-02-27 |
PT66953B (fr) | 1979-11-12 |
US4196209A (en) | 1980-04-01 |
DK142812C (el) | 1981-09-21 |
GB1556919A (en) | 1979-11-28 |
FR2362628B1 (el) | 1979-03-02 |
JPS631312B2 (el) | 1988-01-12 |
AT358582B (de) | 1980-09-25 |
ATA619677A (de) | 1980-02-15 |
CA1103676A (fr) | 1981-06-23 |
SE432595B (sv) | 1984-04-09 |
BE858101A (fr) | 1978-02-27 |
HU172711B (hu) | 1978-11-28 |
IE45574L (en) | 1978-02-26 |
NL7709383A (nl) | 1978-02-28 |
AU2821377A (en) | 1979-03-01 |
AU510037B2 (en) | 1980-06-05 |
IE45574B1 (en) | 1982-10-06 |
DE2738646A1 (de) | 1978-03-02 |
DK376577A (el) | 1978-02-27 |
FR2362628A1 (fr) | 1978-03-24 |
ZA775134B (en) | 1978-09-27 |
CH624952A5 (el) | 1981-08-31 |
ES461875A1 (es) | 1978-05-16 |
CH628344A5 (fr) | 1982-02-26 |
DE2738646C2 (de) | 1985-08-08 |
JPS5328178A (en) | 1978-03-16 |
PT66953A (fr) | 1977-09-01 |
LU78028A1 (el) | 1978-04-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |