DK141750B - Analogifremgangsmåde til fremstilling af 1-(3-(4-m-chlorphenyl-1-piperazinyl)propyl)-3,4-diethyl-delta2,-1,2,4-triazolin-5-on. - Google Patents

Analogifremgangsmåde til fremstilling af 1-(3-(4-m-chlorphenyl-1-piperazinyl)propyl)-3,4-diethyl-delta2,-1,2,4-triazolin-5-on. Download PDF

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Publication number
DK141750B
DK141750B DK535473AA DK535473A DK141750B DK 141750 B DK141750 B DK 141750B DK 535473A A DK535473A A DK 535473AA DK 535473 A DK535473 A DK 535473A DK 141750 B DK141750 B DK 141750B
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DK
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Prior art keywords
diethyl
triazolin
acid
chlorophenyl
propyl
Prior art date
Application number
DK535473AA
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Danish (da)
English (en)
Other versions
DK141750C (it
Inventor
Giuseppe Palazzo
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of DK141750B publication Critical patent/DK141750B/da
Application granted granted Critical
Publication of DK141750C publication Critical patent/DK141750C/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK535473AA 1972-10-16 1973-10-02 Analogifremgangsmåde til fremstilling af 1-(3-(4-m-chlorphenyl-1-piperazinyl)propyl)-3,4-diethyl-delta2,-1,2,4-triazolin-5-on. DK141750B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT53380/72A IT1052119B (it) 1972-10-16 1972-10-16 Derivati del triazolinone e procedimento per la loro preparazione
IT5338072 1972-10-16

Publications (2)

Publication Number Publication Date
DK141750B true DK141750B (da) 1980-06-09
DK141750C DK141750C (it) 1980-11-03

Family

ID=11282276

Family Applications (1)

Application Number Title Priority Date Filing Date
DK535473AA DK141750B (da) 1972-10-16 1973-10-02 Analogifremgangsmåde til fremstilling af 1-(3-(4-m-chlorphenyl-1-piperazinyl)propyl)-3,4-diethyl-delta2,-1,2,4-triazolin-5-on.

Country Status (19)

Country Link
US (1) US3857845A (it)
JP (1) JPS5550948B2 (it)
AR (1) AR204086A1 (it)
AT (1) AT336021B (it)
BE (1) BE806146A (it)
CA (1) CA1013746A (it)
CH (1) CH589643A5 (it)
DE (1) DE2351739C3 (it)
DK (1) DK141750B (it)
ES (1) ES419687A1 (it)
FI (1) FI58495C (it)
FR (1) FR2202702B1 (it)
GB (1) GB1438337A (it)
IT (1) IT1052119B (it)
KE (1) KE2823A (it)
NL (1) NL184782C (it)
NO (1) NO138565C (it)
SE (1) SE390819B (it)
YU (1) YU39914B (it)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1047702B (it) * 1975-07-24 1980-10-20 Acraf Nuova sintesi degli psicofarmaci denominati trazodone ed eteroperidone
US4162318A (en) * 1976-05-05 1979-07-24 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Use of trazodone and etoperidone in Parkinsonism and in other extrapyramidal syndromes characterized by tremors
IT1073639B (it) * 1976-05-05 1985-04-17 Acraf Impiego del trazodone e etoperidone nel morbo di parikinson ed in altre sindromi extrapiramidali caratterizzate da tremori
US4465683A (en) * 1979-09-14 1984-08-14 Mead Johnson & Company Anti-psychotic agents
US4254124A (en) * 1979-09-24 1981-03-03 Mead Johnson & Company Antidepressant agent
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4386091A (en) * 1982-02-24 1983-05-31 Mead Johnson & Company 2-Phenoxyalkyl-1,2,4-triazol-3-one antidepressants
US4575555A (en) * 1983-06-29 1986-03-11 Mead Johnson & Company 4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine derivative
US4613600A (en) * 1983-09-30 1986-09-23 Mead Johnson & Company Antidepressant 1,2,4-triazolone compounds
US4784998A (en) * 1987-04-06 1988-11-15 Bristol-Myers Company 1,3,4-oxadiazole pyschotropic compounds
US4931445A (en) * 1988-10-06 1990-06-05 Irwin Goldstein Agents for treatment of male impotence
US5229406A (en) * 1990-09-19 1993-07-20 G. D. Searle & Co. 1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
US5140036A (en) * 1990-09-19 1992-08-18 G. D. Searle & Co. 1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
US5087634A (en) * 1990-10-31 1992-02-11 G. D. Searle & Co. N-substituted imidazol-2-one compounds for treatment of circulatory disorders
US5238952A (en) * 1990-10-31 1993-08-24 G. D. Searle & Co. N-substituted imidazol-2-one compounds for treatment of circulatory disorders
US5196537A (en) * 1991-03-21 1993-03-23 G. D. Searle & Co. 5-apylheteroarylalkyl-1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
US5164403A (en) * 1991-04-05 1992-11-17 G. D. Searle & Co. N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders
IT1256387B (it) * 1992-11-13 1995-12-04 Acraf Procedimento per preparare triazoloni
CA2182241C (en) * 1996-07-29 2002-09-17 Bo Lei Methods for the manufacture of nefazodone
ES2152860B1 (es) * 1998-10-23 2001-08-16 Finaf 92 Sa Forma cristalina de la nefazodona y procedimiento para su preparacion.
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors

Also Published As

Publication number Publication date
DK141750C (it) 1980-11-03
ATA871173A (de) 1976-08-15
AT336021B (de) 1977-04-12
DE2351739C3 (de) 1980-09-04
NL184782C (nl) 1989-11-01
FI58495B (fi) 1980-10-31
NL7314204A (it) 1974-04-18
AR204086A1 (es) 1975-11-20
DE2351739B2 (de) 1980-01-10
SE390819B (sv) 1977-01-24
IT1052119B (it) 1981-06-20
BE806146A (fr) 1974-02-15
NO138565C (no) 1978-09-27
YU263473A (en) 1983-02-28
JPS4993381A (it) 1974-09-05
US3857845A (en) 1974-12-31
NL184782B (nl) 1989-06-01
YU39914B (en) 1985-06-30
CA1013746A (en) 1977-07-12
JPS5550948B2 (it) 1980-12-20
FR2202702A1 (it) 1974-05-10
NO138565B (no) 1978-06-19
FI58495C (fi) 1981-02-10
ES419687A1 (es) 1976-10-16
GB1438337A (it) 1976-06-03
KE2823A (en) 1978-03-31
FR2202702B1 (it) 1976-07-02
DE2351739A1 (de) 1974-04-18
CH589643A5 (it) 1977-07-15

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PBP Patent lapsed