DK1399458T3 - Fremgangsmåde til arylering af funktionaliserede O-allyl-erythromycin-derivater - Google Patents

Fremgangsmåde til arylering af funktionaliserede O-allyl-erythromycin-derivater

Info

Publication number
DK1399458T3
DK1399458T3 DK02741957T DK02741957T DK1399458T3 DK 1399458 T3 DK1399458 T3 DK 1399458T3 DK 02741957 T DK02741957 T DK 02741957T DK 02741957 T DK02741957 T DK 02741957T DK 1399458 T3 DK1399458 T3 DK 1399458T3
Authority
DK
Denmark
Prior art keywords
erythromycin
heck reaction
derivative
alkenylaryl
arylating
Prior art date
Application number
DK02741957T
Other languages
Danish (da)
English (en)
Inventor
Weijiang Zhang
Margaret Chi-Ping Hsu
Anthony R Haight
Matthew John Peterson
Bikshandarkoil A Narayanan
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK1399458T3 publication Critical patent/DK1399458T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK02741957T 2001-05-30 2002-05-21 Fremgangsmåde til arylering af funktionaliserede O-allyl-erythromycin-derivater DK1399458T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29432601P 2001-05-30 2001-05-30

Publications (1)

Publication Number Publication Date
DK1399458T3 true DK1399458T3 (da) 2005-12-12

Family

ID=23132927

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02741957T DK1399458T3 (da) 2001-05-30 2002-05-21 Fremgangsmåde til arylering af funktionaliserede O-allyl-erythromycin-derivater

Country Status (16)

Country Link
US (1) US7071314B2 (es)
EP (1) EP1399458B1 (es)
JP (1) JP2004536075A (es)
KR (1) KR20040014537A (es)
CN (1) CN100422201C (es)
AT (1) ATE301128T1 (es)
BR (1) BR0206106A (es)
CA (1) CA2449173A1 (es)
DE (1) DE60205377T2 (es)
DK (1) DK1399458T3 (es)
ES (1) ES2246403T3 (es)
HK (1) HK1064390A1 (es)
IL (1) IL159004A0 (es)
MX (1) MXPA03010939A (es)
TW (1) TWI246515B (es)
WO (1) WO2002096922A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2343141T3 (es) * 2005-11-16 2010-07-23 F. Hoffmann-La Roche Ag Nuevo procedimiento para la preparacion de thoc.
US7595300B2 (en) * 2005-12-13 2009-09-29 Kosan Biosciences Incorporated 7-quinolyl ketolide antibacterial agents
US8293715B2 (en) 2007-08-06 2012-10-23 Taisho Pharmaceutical Co., Ltd. 10a-Azalide compound crosslinked at 10a- and 12-positions
WO2009139181A1 (ja) 2008-05-15 2009-11-19 大正製薬株式会社 ４員環構造を有する１０ａ－アザライド化合物
KR200457752Y1 (ko) * 2008-12-02 2012-01-02 다폰 일렉트로닉스 코퍼레이션 변압기 및 백라이트 장치
CN102766181A (zh) * 2011-05-06 2012-11-07 上海医药工业研究院 6-o-取代的红霉素衍生物的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331803A (en) 1980-06-04 1982-05-25 Taisho Pharmaceutical Co., Ltd. Novel erythromycin compounds
JPS5896097A (ja) 1981-12-01 1983-06-07 Taisho Pharmaceut Co Ltd エリスロマイシンｂ誘導体
US5872229A (en) 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
AU2340797A (en) 1996-05-07 1997-11-26 Abbott Laboratories 6-o-substituted erythromycins and method for making them
UA51730C2 (uk) 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
ZA987689B (en) * 1997-09-02 1999-02-24 Abbott Lab 3-descladinose 6-O substituted erythromycin derivatives
US6124269A (en) 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
US5932710A (en) 1997-12-01 1999-08-03 Abbott Laboratories Process for preparing 6-O-alkyl-9-oxime erythromycin B
IL135792A0 (en) 1997-12-01 2001-05-20 Abbott Lab 6-o-alkyl derivatives of erythronolide b
US6040440A (en) 1998-03-06 2000-03-21 Abbott Laboratories Hypophosphite deoxygenation reactions in the synthesis of erythromycin derivatives
DK1161438T3 (da) * 1999-03-15 2004-08-30 Abbott Lab 6-O-substituerede makrolider, som har antibakteriel aktivitet
US6437106B1 (en) * 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives

Also Published As

Publication number Publication date
EP1399458B1 (en) 2005-08-03
KR20040014537A (ko) 2004-02-14
US20030125531A1 (en) 2003-07-03
JP2004536075A (ja) 2004-12-02
DE60205377T2 (de) 2006-05-24
BR0206106A (pt) 2003-10-14
CA2449173A1 (en) 2002-12-05
CN1633443A (zh) 2005-06-29
HK1064390A1 (en) 2005-01-28
US7071314B2 (en) 2006-07-04
EP1399458A1 (en) 2004-03-24
ATE301128T1 (de) 2005-08-15
IL159004A0 (en) 2004-05-12
DE60205377D1 (de) 2005-09-08
TWI246515B (en) 2006-01-01
MXPA03010939A (es) 2004-02-27
CN100422201C (zh) 2008-10-01
ES2246403T3 (es) 2006-02-16
WO2002096922A1 (en) 2002-12-05

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