DK1358332T3 - En serpin i Bifidobakterier - Google Patents
En serpin i BifidobakterierInfo
- Publication number
- DK1358332T3 DK1358332T3 DK02718062T DK02718062T DK1358332T3 DK 1358332 T3 DK1358332 T3 DK 1358332T3 DK 02718062 T DK02718062 T DK 02718062T DK 02718062 T DK02718062 T DK 02718062T DK 1358332 T3 DK1358332 T3 DK 1358332T3
- Authority
- DK
- Denmark
- Prior art keywords
- sequences
- polypeptides
- ncc2705
- pertains
- sequence
- Prior art date
Links
- 241000186000 Bifidobacterium Species 0.000 title abstract 2
- 102000008847 Serpin Human genes 0.000 title 1
- 108050000761 Serpin Proteins 0.000 title 1
- 239000003001 serine protease inhibitor Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 241001608472 Bifidobacterium longum Species 0.000 abstract 1
- 206010012735 Diarrhoea Diseases 0.000 abstract 1
- 241000702670 Rotavirus Species 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 229940009291 bifidobacterium longum Drugs 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- LWGJTAZLEJHCPA-UHFFFAOYSA-N n-(2-chloroethyl)-n-nitrosomorpholine-4-carboxamide Chemical compound ClCCN(N=O)C(=O)N1CCOCC1 LWGJTAZLEJHCPA-UHFFFAOYSA-N 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 230000002103 transcriptional effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
- A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C2220/00—Biochemical treatment
- A23C2220/20—Treatment with microorganisms
- A23C2220/202—Genetic engineering of microorganisms used in dairy technology
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
- G01N2333/8121—Serpins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Polymers & Plastics (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01102050A EP1227152A1 (de) | 2001-01-30 | 2001-01-30 | Bakterienstamm und Genom des Bifidobacteriums |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1358332T3 true DK1358332T3 (da) | 2007-01-08 |
Family
ID=8176339
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02718062T DK1358332T3 (da) | 2001-01-30 | 2002-01-30 | En serpin i Bifidobakterier |
Country Status (12)
Country | Link |
---|---|
US (2) | US7700315B2 (de) |
EP (3) | EP1227152A1 (de) |
JP (2) | JP4249483B2 (de) |
CN (3) | CN100558896C (de) |
AT (1) | ATE342986T1 (de) |
AU (3) | AU2002247668A1 (de) |
CA (2) | CA2436049C (de) |
DE (1) | DE60215461T2 (de) |
DK (1) | DK1358332T3 (de) |
ES (2) | ES2274019T3 (de) |
PT (2) | PT1360299E (de) |
WO (3) | WO2002060932A2 (de) |
Families Citing this family (111)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001241934A1 (en) | 2000-03-03 | 2001-09-17 | Beckman Coulter Inc. | Multiplex hybridization system for identification of pathogenic mycobacterium and method of use |
EP1227152A1 (de) * | 2001-01-30 | 2002-07-31 | Société des Produits Nestlé S.A. | Bakterienstamm und Genom des Bifidobacteriums |
EP1264893A1 (de) * | 2001-06-08 | 2002-12-11 | Teagasc Dairy Products Research Centre | Biosynthese von CLA durch Bifidobakterien |
JP4074251B2 (ja) | 2001-12-03 | 2008-04-09 | 協和醗酵工業株式会社 | 変異型6−ホスホグルコン酸デヒドロゲナーゼ |
CA2496990A1 (en) * | 2002-08-23 | 2004-03-04 | E.I. Du Pont De Nemours And Company | Utilization of starch products for biological production by fermentation |
EP2228379A1 (de) | 2003-04-25 | 2010-09-15 | North Carolina State University | Für Zelloberflächenproteinhomologe codierende Nukleinsäuresequenzen aus Lactobacillus acidophilus |
US7407787B2 (en) | 2003-06-23 | 2008-08-05 | North Carolina State University | Lactobacillus acidophilus nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof |
WO2005000882A2 (en) * | 2003-06-27 | 2005-01-06 | University College Cork - National University Of Ireland, Cork | Dna fragments and proteins encoded by said dna isolated from bifidobacteria |
ATE360682T1 (de) | 2003-06-30 | 2007-05-15 | Clasado Inc | Neue galactooligosaccharidzusammensetzung und herstellung davon |
KR100492455B1 (ko) * | 2003-09-26 | 2005-05-30 | 주식회사 비피도 | 로바타바이러스 억제활성을 갖는 신균주 비피도 박테리움 롱검 에이알81 및 이로부터 분리된 활성단백질 |
WO2005034971A2 (en) * | 2003-10-08 | 2005-04-21 | Masami Moriyama | Antiviral agent |
US20050158294A1 (en) | 2003-12-19 | 2005-07-21 | The Procter & Gamble Company | Canine probiotic Bifidobacteria pseudolongum |
US8877178B2 (en) | 2003-12-19 | 2014-11-04 | The Iams Company | Methods of use of probiotic bifidobacteria for companion animals |
US7455992B2 (en) | 2004-02-23 | 2008-11-25 | North Carolina State University | Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore |
WO2005085478A2 (en) * | 2004-02-27 | 2005-09-15 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Detection and identification of mycobacterium and nocardia using primers and probes directed to the seca1 gene |
US7608700B2 (en) | 2004-03-08 | 2009-10-27 | North Carolina State University | Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor |
US7459289B2 (en) | 2004-03-08 | 2008-12-02 | North Carolina State University | Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor |
US7550576B2 (en) | 2004-08-09 | 2009-06-23 | North Carolina State University | Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor |
JP4784224B2 (ja) * | 2004-09-24 | 2011-10-05 | 味の素株式会社 | 糖鎖転移方法および糖鎖転移酵素 |
JP2008517628A (ja) | 2004-10-27 | 2008-05-29 | ノース カロライナ ステイト ユニヴァーシティー | ラクトバチルス・アシドフィルス核酸及びその使用 |
US7495092B2 (en) | 2005-01-14 | 2009-02-24 | North Carolina State University | Compositions comprising promoter sequences and methods of use |
EP1856148B8 (de) | 2005-03-07 | 2013-04-10 | Barbara Kofler | Neuropeptide |
ATE432337T1 (de) * | 2005-05-16 | 2009-06-15 | Univ Liege | Probiotische bifidobacterium arten |
AU2006253006B8 (en) | 2005-05-31 | 2011-09-15 | Alimentary Health Ltd | Feline probiotic Lactobacilli |
BRPI0611492B1 (pt) | 2005-05-31 | 2021-10-13 | Mars, Incorporated | Bifidobactéria probiótica felina |
GB0525857D0 (en) * | 2005-12-20 | 2006-02-01 | Product and process | |
GB0601901D0 (en) | 2006-01-31 | 2006-03-08 | Product and Process | |
GB0606112D0 (en) | 2006-03-28 | 2006-05-03 | Product and process | |
CN100389125C (zh) * | 2006-05-30 | 2008-05-21 | 中国科学院昆明动物研究所 | 无指盘臭蛙丙精肽、基因和变异体 |
ES2551719T3 (es) | 2007-02-01 | 2015-11-23 | Iams Europe B.V. | Procedimiento para disminuir la inflamación y el estrés en un mamífero usando antimetabolitos de glucosa, aguacate o extractos de aguacate |
CN101273736B (zh) * | 2007-03-28 | 2012-08-08 | 北京弗蒙特生物技术有限公司 | 一种在常温下保持高活菌数的发酵乳的制备方法 |
EP2179028B1 (de) * | 2007-06-27 | 2014-08-13 | Laboratorios Ordesa, S.l. | Neuer bifidobacterium-stamm und aktive peptide gegen rotavirusinfektionen |
EP2053122A1 (de) * | 2007-10-23 | 2009-04-29 | Nestec S.A. | Stresstolerante Bifidobakterien |
US9730968B2 (en) | 2008-04-17 | 2017-08-15 | Anaeropharma Science, Inc. | Therapeutic agent for ischemic diseases |
CN101570755B (zh) * | 2008-04-29 | 2011-09-28 | 中国农业科学院植物保护研究所 | 一种细菌源蛋白酶抑制剂新基因及其表达与应用 |
US9771199B2 (en) | 2008-07-07 | 2017-09-26 | Mars, Incorporated | Probiotic supplement, process for making, and packaging |
US9232813B2 (en) * | 2008-07-07 | 2016-01-12 | The Iams Company | Probiotic supplement, process for making, and packaging |
EP2352389B1 (de) | 2008-11-11 | 2016-01-06 | Alimentary Health Limited | Bifidobacterium longum |
EP2429538B1 (de) | 2009-05-11 | 2015-10-21 | Nestec S.A. | Nicht-replizierende bifidobacterium longum ncc2705 und immunerkrankungen |
US11065268B2 (en) | 2009-05-27 | 2021-07-20 | Clasado Research Services Limited | Method of preventing diarrhoea |
EP2270134A1 (de) * | 2009-07-03 | 2011-01-05 | Nestec S.A. | Gegen oxidativen Stress resistente Bifido-Bakterien |
US10104903B2 (en) | 2009-07-31 | 2018-10-23 | Mars, Incorporated | Animal food and its appearance |
BR112012003633A2 (pt) * | 2009-08-18 | 2015-09-01 | Nestec Sa | "composição nutricional que compreende cepas de bifidobacterium longum e reduz os sintomas de alergia alimentar, especialmente em bebês e crianças." |
WO2011027875A1 (ja) * | 2009-09-03 | 2011-03-10 | 独立行政法人理化学研究所 | 腸管バリア機能改善剤 |
RU2557310C2 (ru) * | 2009-11-11 | 2015-07-20 | Алиментари Хелс Лимитед | ШТАММ Bifidobacterium longum, ПРИГОДНЫЙ ДЛЯ ПРИМЕНЕНИЯ В ИММУНОМОДУЛЯЦИИ, ИНДУКЦИИ ПРОДУКЦИИ ЦИТОКИНОВ, ЛЕЧЕНИИ АУТОИММУННОГО ЗАБОЛЕВАНИЯ, КОНТРОЛЕ ОТНОШЕНИЯ IL - 10:IL - 12, И ЕГО ИСПОЛЬЗОВАНИЕ |
EP2451467B1 (de) * | 2010-01-14 | 2016-12-21 | INSERM - Institut National de la Santé et de la Recherche Médicale | Rekombinante probiotische bakterien zur vorbeugung und behandlung der chronisch-entzündlichen darmerkrankung und des reizdarmsyndroms |
WO2011093467A1 (ja) * | 2010-01-29 | 2011-08-04 | 株式会社アネロファーマ・サイエンス | 形質転換用プラスミド |
US8755425B2 (en) * | 2010-06-30 | 2014-06-17 | Comtech Ef Data Corp. | Method and system for transmission of identification via metadata for repeating relays using spread-spectrum technology |
CN101880668B (zh) * | 2010-05-07 | 2012-05-23 | 广西大学 | 一种编码丝氨酸蛋白酶抑制剂的基因及其应用 |
EP2397145A1 (de) * | 2010-06-18 | 2011-12-21 | Nestec S.A. | L. johnsonii La1, B. longum NCC2705 und Immunerkrankungen |
CN101884782B (zh) * | 2010-06-29 | 2015-09-16 | 南昌大学 | 长双歧杆菌粘附抑制蛋白Aip在防治腹泻中的应用 |
RU2553295C2 (ru) | 2010-07-02 | 2015-06-10 | Дзе Проктер Энд Гэмбл Компани | Моющий продукт и способы его изготовления |
CN105332075B (zh) | 2010-07-02 | 2017-11-24 | 宝洁公司 | 包含活性剂的长丝、非织造纤维网和制备它们的方法 |
BR112013000044B1 (pt) | 2010-07-02 | 2022-01-04 | The Procter & Gamble Company | Método para a distribuição de agentes ativos a artigos de tecido ou superfícies duras |
EP2449891A1 (de) * | 2010-11-05 | 2012-05-09 | Nestec S.A. | Trinkjoghurtzubereitungen mit nicht-replizierenden probiotischen Mikroorganismen |
GB201021399D0 (en) | 2010-12-16 | 2011-01-26 | Genetic Analysis As | Oligonucleotide probe set and methods of microbiota profiling |
TWI487530B (zh) * | 2011-01-10 | 2015-06-11 | 可產生高免疫激活反應之比菲德氏龍根菌分離株 | |
KR20140046463A (ko) * | 2011-07-13 | 2014-04-18 | 가부시키가이샤 아네로파마·사이엔스 | 허혈성질환 치료제 |
GB201112091D0 (en) | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
GB201117313D0 (en) | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
RU2527069C2 (ru) * | 2011-11-08 | 2014-08-27 | Автономная Некоммерческая Организация "Научно-исследовательский центр биотехнологи антибиотиков и других биологически активных веществ "БИОАН" | СПОСОБ ВИДОВОЙ И ШТАММОВОЙ ИДЕНТИФИКАЦИИ БИФИДОБАКТЕРИЙ ФИЛОТИПА Bifidobacterium longum |
BR112014021388A2 (pt) | 2012-02-29 | 2017-07-18 | Ethicon Endo Surgery Inc | composições de microbiota e métodos rela-cionados às mesmas |
US8686114B2 (en) | 2012-03-05 | 2014-04-01 | E I Du Pont De Nemours And Company | Variant sucrose transporter polypeptides |
US9161957B2 (en) | 2012-08-03 | 2015-10-20 | Life Well Lived, Llc | Compositions and methods for reducing blood alcohol content |
JP6752016B2 (ja) * | 2012-10-17 | 2020-09-09 | アンテローム | 肝臓に関する炎症性障害の遺伝子シグネチャー |
FR2999933B1 (fr) * | 2012-12-21 | 2020-01-31 | Société des Produits Nestlé S.A. | Utilisation de microorganismes probiotiques comme agent favorisant la synthese de melanine |
GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
US9861666B2 (en) | 2013-08-12 | 2018-01-09 | Mansel Griffiths | Antiviral methods and compositions comprising probiotic bacterial molecules |
JP6634625B2 (ja) * | 2014-05-01 | 2020-01-22 | 株式会社アネロファーマ・サイエンス | 異種ポリペプチド発現カセット |
SG11201609108TA (en) | 2014-05-02 | 2016-12-29 | Univ Shinshu | Antibody gene expression-secretion system |
GB2551642B (en) | 2014-10-31 | 2020-09-23 | Pendulum Therapeutics Inc | Methods and compositions relating to microbial treatment and diagnosis of disorders |
SG11201704450UA (en) | 2014-12-03 | 2017-06-29 | Anaeropharma Science Inc | Coexpression plasmid |
MX2017008449A (es) | 2014-12-23 | 2017-10-12 | 4D Pharma Res Ltd | Polipeptido de pirina y modulacion inmune. |
US20180267037A1 (en) * | 2014-12-23 | 2018-09-20 | Evolve Biosystems Inc. | Method for the noninvasive detection of activated bifidobacteria |
CN113862175A (zh) | 2014-12-23 | 2021-12-31 | 4D制药研究有限公司 | 免疫调控 |
GB201508860D0 (en) | 2015-05-22 | 2015-07-01 | Nat Univ Ireland | Diagnostic method |
AU2016278067B2 (en) | 2015-06-15 | 2022-09-22 | Cj Bioscience, Inc. | Compositions comprising bacterial strains |
MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
CA2988695A1 (en) | 2015-06-15 | 2016-12-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
CN114984057A (zh) | 2015-06-15 | 2022-09-02 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
PT3209310T (pt) | 2015-11-20 | 2018-04-20 | 4D Pharma Res Ltd | Composições compreendendo estirpes bacterianas |
GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
CA3016179C (en) | 2016-03-04 | 2019-08-13 | 4D Pharma Plc | Compositions comprising bacterial blautia strains for treating visceral hypersensitivity |
CN105694892A (zh) * | 2016-03-16 | 2016-06-22 | 山东大学 | 一种表面带正电荷的CdSe量子点的制备方法 |
TWI802545B (zh) | 2016-07-13 | 2023-05-21 | 英商4D製藥有限公司 | 包含細菌菌株之組合物 |
US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
CN106478812B (zh) * | 2016-10-21 | 2020-11-20 | 沈阳药科大学 | 丝氨酸蛋白酶抑制剂-3及其功能、制备方法和应用 |
GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
MX2019008761A (es) | 2017-01-27 | 2019-09-18 | Procter & Gamble | Composiciones en la forma de estructuras solidas solubles que comprenden particulas aglomeradas efervescentes. |
AR111589A1 (es) | 2017-04-11 | 2019-07-31 | Chr Hansen As | Enzimas lactasas con propiedades mejoradas |
PL3630136T3 (pl) | 2017-05-22 | 2021-09-13 | 4D Pharma Research Limited | Kompozycje zawierające szczepy bakteryjne |
WO2018215782A1 (en) | 2017-05-24 | 2018-11-29 | 4D Pharma Research Limited | Compositions comprising bacterial strain |
DK3600364T3 (da) | 2017-06-14 | 2020-08-31 | 4D Pharma Res Ltd | Sammensætninger omfattende en bakteriestamme af slægten megasphaera og anvendelser deraf |
WO2018229188A1 (en) | 2017-06-14 | 2018-12-20 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
JP2020532515A (ja) | 2017-08-30 | 2020-11-12 | ペンデュラム セラピューティクス, インコーポレイテッド | マイクロバイオーム関連障害の処置のための方法および組成物 |
WO2019055940A1 (en) * | 2017-09-18 | 2019-03-21 | Dupont Nutrition Biosciences Aps | ENZYMES RIBOFLAVINASES AND THEIR USE FOR REMOVING AROMA DURING BREWING |
US11666514B2 (en) | 2018-09-21 | 2023-06-06 | The Procter & Gamble Company | Fibrous structures containing polymer matrix particles with perfume ingredients |
BR112021007244A2 (pt) * | 2018-10-17 | 2021-08-10 | Chr. Hansen A/S | enzimas lactase com propriedades melhoradas em ph ácido |
CN110343672B (zh) * | 2018-12-27 | 2021-07-06 | 华东理工大学 | 一种抗尿苷酸反馈抑制的氨甲酰磷酸合成酶突变体及其应用 |
JP2021083433A (ja) * | 2019-11-29 | 2021-06-03 | 地方独立行政法人神奈川県立産業技術総合研究所 | 抗原結合分子、核酸組成物、ベクター組成物、細胞およびBifidobacterium longumの精製方法 |
MX2023001042A (es) | 2020-07-31 | 2023-02-16 | Procter & Gamble | Bolsa fibrosa soluble en agua que contiene granulos para el cuidado del cabello. |
CN112458015B (zh) * | 2020-11-27 | 2021-11-19 | 石家庄君乐宝乳业有限公司 | 长双歧杆菌长亚种i772、其分离纯化方法及应用 |
KR102277034B1 (ko) * | 2021-01-29 | 2021-07-13 | 씨제이제일제당 (주) | 신규한 dahp 신타아제 변이체 및 이를 이용한 l-라이신 생산 방법 |
CN113957073B (zh) * | 2021-10-19 | 2023-09-01 | 山东寿光巨能金玉米开发有限公司 | 一种tkt基因启动子突变体及其在生产L-赖氨酸中的应用 |
CN114774335B (zh) * | 2022-06-22 | 2022-09-02 | 广东省科学院微生物研究所(广东省微生物分析检测中心) | 具有靶向葡萄糖激酶显著降血糖和降血脂功效的长双歧杆菌070103及其应用 |
CN116814822B (zh) * | 2023-08-25 | 2023-11-24 | 中国食品发酵工业研究院有限公司 | 一种长双歧杆菌婴儿亚种cicc 6069菌株的鉴定方法和应用 |
CN117551799B (zh) * | 2024-01-11 | 2024-03-19 | 广东海洋大学 | 用于鰤鱼诺卡氏菌菌株分型的引物组合、多重pcr鉴定方法及应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0687732B2 (ja) * | 1987-02-25 | 1994-11-09 | カルピス食品工業株式会社 | ビフイズス菌入り発酵乳の製造法 |
ES2102485T3 (es) * | 1992-07-06 | 1997-08-01 | Nestle Sa | Bacteria lactica. |
US6737248B2 (en) * | 1996-01-05 | 2004-05-18 | Human Genome Sciences, Inc. | Staphylococcus aureus polynucleotides and sequences |
EP1770164B1 (de) * | 1996-10-31 | 2010-09-01 | Human Genome Sciences, Inc. | Streptococcus pneumoniae-Antigene und Impfstoffe |
WO1998050555A2 (en) * | 1997-05-06 | 1998-11-12 | Human Genome Sciences, Inc. | Enterococcus faecalis polynucleotides and polypeptides |
JP4046389B2 (ja) * | 1997-09-04 | 2008-02-13 | 株式会社ヤクルト本社 | ビフィドバクテリウム・ブレーベ及びこれを用いた発酵豆乳 |
EP1227152A1 (de) * | 2001-01-30 | 2002-07-31 | Société des Produits Nestlé S.A. | Bakterienstamm und Genom des Bifidobacteriums |
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