DK1305047T3 - Ikke-peptidiske CCR1-receptor-antagonister i kombination med cyclosporin A til behandling af hjertetransplantatafstödning - Google Patents

Ikke-peptidiske CCR1-receptor-antagonister i kombination med cyclosporin A til behandling af hjertetransplantatafstödning

Info

Publication number
DK1305047T3
DK1305047T3 DK01956035T DK01956035T DK1305047T3 DK 1305047 T3 DK1305047 T3 DK 1305047T3 DK 01956035 T DK01956035 T DK 01956035T DK 01956035 T DK01956035 T DK 01956035T DK 1305047 T3 DK1305047 T3 DK 1305047T3
Authority
DK
Denmark
Prior art keywords
cyclosporin
peptidic
treatment
combination
receptor antagonists
Prior art date
Application number
DK01956035T
Other languages
English (en)
Inventor
Richard Horuk
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK1305047T3 publication Critical patent/DK1305047T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK01956035T 2000-07-31 2001-07-31 Ikke-peptidiske CCR1-receptor-antagonister i kombination med cyclosporin A til behandling af hjertetransplantatafstödning DK1305047T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22205300P 2000-07-31 2000-07-31
US23128200P 2000-09-08 2000-09-08
US09/915,411 US6740636B2 (en) 2000-07-31 2001-07-25 Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection

Publications (1)

Publication Number Publication Date
DK1305047T3 true DK1305047T3 (da) 2006-10-23

Family

ID=27397025

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01956035T DK1305047T3 (da) 2000-07-31 2001-07-31 Ikke-peptidiske CCR1-receptor-antagonister i kombination med cyclosporin A til behandling af hjertetransplantatafstödning

Country Status (28)

Country Link
US (1) US6740636B2 (da)
EP (1) EP1305047B1 (da)
JP (1) JP2004530630A (da)
KR (1) KR20030048000A (da)
CN (1) CN1655818A (da)
AT (1) ATE330634T1 (da)
AU (2) AU7807301A (da)
BG (1) BG107502A (da)
BR (1) BR0113140A (da)
CA (1) CA2417636A1 (da)
CY (1) CY1105321T1 (da)
DE (1) DE60120986T2 (da)
DK (1) DK1305047T3 (da)
EE (1) EE200300047A (da)
ES (1) ES2261447T3 (da)
HR (1) HRP20030121A2 (da)
HU (1) HUP0300686A3 (da)
IL (1) IL153933A0 (da)
LV (1) LV13033B (da)
MX (1) MXPA03000836A (da)
NO (1) NO20030475L (da)
NZ (1) NZ523688A (da)
PL (1) PL364521A1 (da)
PT (1) PT1305047E (da)
SI (1) SI21123A (da)
SK (1) SK1222003A3 (da)
WO (1) WO2002009762A2 (da)
YU (1) YU6703A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2006108865A (ru) * 2003-08-22 2007-09-27 Шеринг Акциенгезельшафт (De) Производные пиперазина, которые ингибируют хемокины, и их применение для лечения миокардита
US7917195B2 (en) 2004-03-05 2011-03-29 Lifesciences Solutions LLC Systems, methods and computer program products for heart monitoring
US10499828B2 (en) * 2004-03-05 2019-12-10 Lifescience Solutions, Llc System and method for heart monitoring
US8103065B2 (en) * 2006-01-05 2012-01-24 Lifescience Solutions Llc Assessment of medical conditions
US20110009758A1 (en) * 2009-07-10 2011-01-13 Lifescience Solutions Llc System and method for heart monitoring

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323206B1 (en) 1996-07-12 2001-11-27 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
CN1248968A (zh) 1997-02-26 2000-03-29 辉瑞大药厂 杂芳基-己酸酰胺衍生物、其制备方法及其作为MIP-1α与其CCRI受体结合的选择性抑制剂的用途
US6207665B1 (en) * 1997-06-12 2001-03-27 Schering Aktiengesellschaft Piperazine derivatives and their use as anti-inflammatory agents
US6433165B1 (en) 1998-01-21 2002-08-13 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
BR9910144A (pt) 1998-01-21 2002-04-02 Millennium Pharm Inc Antagonistas de receptores de quimiocinas e seu uso
KR100385529B1 (ko) 1998-02-05 2003-05-27 화이자 프로덕츠 인코포레이티드 신규 디하이드록시헥산산 유도체
EP1000626A1 (en) 1998-09-18 2000-05-17 Applied Research Systems ARS Holding N.V. Chemokine receptor antagonist and cyclosporin in combined therapy
AU2862300A (en) 1999-01-29 2000-08-18 Millennium Pharmaceuticals, Inc. Methods for preventing graft rejection and ischemia-reperfusion injury

Also Published As

Publication number Publication date
WO2002009762A2 (en) 2002-02-07
WO2002009762A3 (en) 2003-01-09
SI21123A (sl) 2003-08-31
DE60120986D1 (de) 2006-08-03
ATE330634T1 (de) 2006-07-15
MXPA03000836A (es) 2003-06-06
BR0113140A (pt) 2003-06-24
CN1655818A (zh) 2005-08-17
CA2417636A1 (en) 2002-02-07
AU2001278073B2 (en) 2005-06-30
SK1222003A3 (en) 2003-09-11
NO20030475D0 (no) 2003-01-30
DE60120986T2 (de) 2006-11-23
HRP20030121A2 (en) 2005-02-28
JP2004530630A (ja) 2004-10-07
EE200300047A (et) 2004-10-15
CY1105321T1 (el) 2010-03-03
US6740636B2 (en) 2004-05-25
IL153933A0 (en) 2003-07-31
EP1305047A2 (en) 2003-05-02
LV13033B (en) 2004-02-20
US20020039997A1 (en) 2002-04-04
EP1305047B1 (en) 2006-06-21
NZ523688A (en) 2005-04-29
HUP0300686A2 (hu) 2003-08-28
PT1305047E (pt) 2006-11-30
HUP0300686A3 (en) 2005-03-29
ES2261447T3 (es) 2006-11-16
PL364521A1 (en) 2004-12-13
BG107502A (en) 2003-07-31
AU7807301A (en) 2002-02-13
NO20030475L (no) 2003-03-28
KR20030048000A (ko) 2003-06-18
YU6703A (sh) 2006-05-25

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