IL153933A0 - Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection - Google Patents

Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection

Info

Publication number
IL153933A0
IL153933A0 IL15393301A IL15393301A IL153933A0 IL 153933 A0 IL153933 A0 IL 153933A0 IL 15393301 A IL15393301 A IL 15393301A IL 15393301 A IL15393301 A IL 15393301A IL 153933 A0 IL153933 A0 IL 153933A0
Authority
IL
Israel
Prior art keywords
cyclosporin
transplant rejection
heart transplant
treatment
combination
Prior art date
Application number
IL15393301A
Other languages
English (en)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL153933A0 publication Critical patent/IL153933A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15393301A 2000-07-31 2001-07-31 Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection IL153933A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22205300P 2000-07-31 2000-07-31
US23128200P 2000-09-08 2000-09-08
US09/915,411 US6740636B2 (en) 2000-07-31 2001-07-25 Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
PCT/US2001/023862 WO2002009762A2 (en) 2000-07-31 2001-07-31 Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection

Publications (1)

Publication Number Publication Date
IL153933A0 true IL153933A0 (en) 2003-07-31

Family

ID=27397025

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15393301A IL153933A0 (en) 2000-07-31 2001-07-31 Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection

Country Status (28)

Country Link
US (1) US6740636B2 (xx)
EP (1) EP1305047B1 (xx)
JP (1) JP2004530630A (xx)
KR (1) KR20030048000A (xx)
CN (1) CN1655818A (xx)
AT (1) ATE330634T1 (xx)
AU (2) AU7807301A (xx)
BG (1) BG107502A (xx)
BR (1) BR0113140A (xx)
CA (1) CA2417636A1 (xx)
CY (1) CY1105321T1 (xx)
DE (1) DE60120986T2 (xx)
DK (1) DK1305047T3 (xx)
EE (1) EE200300047A (xx)
ES (1) ES2261447T3 (xx)
HR (1) HRP20030121A2 (xx)
HU (1) HUP0300686A3 (xx)
IL (1) IL153933A0 (xx)
LV (1) LV13033B (xx)
MX (1) MXPA03000836A (xx)
NO (1) NO20030475L (xx)
NZ (1) NZ523688A (xx)
PL (1) PL364521A1 (xx)
PT (1) PT1305047E (xx)
SI (1) SI21123A (xx)
SK (1) SK1222003A3 (xx)
WO (1) WO2002009762A2 (xx)
YU (1) YU6703A (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06002053A (es) * 2003-08-22 2006-08-11 Schering Ag Derivados de piperazina que inhiben quimiocina y su uso para tratar miocarditis.
US10499828B2 (en) * 2004-03-05 2019-12-10 Lifescience Solutions, Llc System and method for heart monitoring
US7917195B2 (en) 2004-03-05 2011-03-29 Lifesciences Solutions LLC Systems, methods and computer program products for heart monitoring
US8103065B2 (en) * 2006-01-05 2012-01-24 Lifescience Solutions Llc Assessment of medical conditions
US20110009758A1 (en) * 2009-07-10 2011-01-13 Lifescience Solutions Llc System and method for heart monitoring

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323206B1 (en) 1996-07-12 2001-11-27 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6403587B1 (en) 1997-02-26 2002-06-11 Pfizer Inc. Heteroaryl-hexanoic acid amide derivatives, their preparation and their use as selective inhibitors of MIP-1-α binding to its CCR 1 receptor
US6207665B1 (en) 1997-06-12 2001-03-27 Schering Aktiengesellschaft Piperazine derivatives and their use as anti-inflammatory agents
CA2319077A1 (en) 1998-01-21 1999-07-29 Yoshisuke Nakasato Chemokine receptor antagonists and methods of use therefor
EP1047675A1 (en) 1998-01-21 2000-11-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
SK11262000A3 (sk) 1998-02-05 2001-01-18 Pfizer Products Inc. Deriváty dihydroxyhexánovej kyseliny a farmaceutický prostriedok,ktorý ich obsahuje
EP1000626A1 (en) 1998-09-18 2000-05-17 Applied Research Systems ARS Holding N.V. Chemokine receptor antagonist and cyclosporin in combined therapy
EP1152752A1 (en) 1999-01-29 2001-11-14 Millennium Pharmaceuticals, Inc. Methods for preventing graft rejection and ischemia-reperfusion injury

Also Published As

Publication number Publication date
LV13033B (en) 2004-02-20
WO2002009762A2 (en) 2002-02-07
EP1305047B1 (en) 2006-06-21
WO2002009762A3 (en) 2003-01-09
DE60120986D1 (de) 2006-08-03
KR20030048000A (ko) 2003-06-18
CA2417636A1 (en) 2002-02-07
DK1305047T3 (da) 2006-10-23
PT1305047E (pt) 2006-11-30
AU2001278073B2 (en) 2005-06-30
HUP0300686A2 (hu) 2003-08-28
NO20030475D0 (no) 2003-01-30
BR0113140A (pt) 2003-06-24
NO20030475L (no) 2003-03-28
AU7807301A (en) 2002-02-13
BG107502A (en) 2003-07-31
HRP20030121A2 (en) 2005-02-28
JP2004530630A (ja) 2004-10-07
HUP0300686A3 (en) 2005-03-29
ES2261447T3 (es) 2006-11-16
ATE330634T1 (de) 2006-07-15
CN1655818A (zh) 2005-08-17
US20020039997A1 (en) 2002-04-04
CY1105321T1 (el) 2010-03-03
NZ523688A (en) 2005-04-29
EP1305047A2 (en) 2003-05-02
YU6703A (sh) 2006-05-25
DE60120986T2 (de) 2006-11-23
SK1222003A3 (en) 2003-09-11
PL364521A1 (en) 2004-12-13
SI21123A (sl) 2003-08-31
US6740636B2 (en) 2004-05-25
MXPA03000836A (es) 2003-06-06
EE200300047A (et) 2004-10-15

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