BG107502A - Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection - Google Patents

Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection

Info

Publication number
BG107502A
BG107502A BG107502A BG10750203A BG107502A BG 107502 A BG107502 A BG 107502A BG 107502 A BG107502 A BG 107502A BG 10750203 A BG10750203 A BG 10750203A BG 107502 A BG107502 A BG 107502A
Authority
BG
Bulgaria
Prior art keywords
cyclosporin
transplant rejection
heart transplant
treatment
combination
Prior art date
Application number
BG107502A
Other languages
Bulgarian (bg)
English (en)
Inventor
Richard Horuk
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of BG107502A publication Critical patent/BG107502A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG107502A 2000-07-31 2003-01-27 Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection BG107502A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22205300P 2000-07-31 2000-07-31
US23128200P 2000-09-08 2000-09-08
US09/915,411 US6740636B2 (en) 2000-07-31 2001-07-25 Non-peptide CCR1 receptor antagonists in combination with cyclosporin A for the treatment of heart transplant rejection
PCT/US2001/023862 WO2002009762A2 (en) 2000-07-31 2001-07-31 Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection

Publications (1)

Publication Number Publication Date
BG107502A true BG107502A (en) 2003-07-31

Family

ID=27397025

Family Applications (1)

Application Number Title Priority Date Filing Date
BG107502A BG107502A (en) 2000-07-31 2003-01-27 Non-peptide ccr1 receptor antagonists in combination with cyclosporin a for the treatment of heart transplant rejection

Country Status (28)

Country Link
US (1) US6740636B2 (xx)
EP (1) EP1305047B1 (xx)
JP (1) JP2004530630A (xx)
KR (1) KR20030048000A (xx)
CN (1) CN1655818A (xx)
AT (1) ATE330634T1 (xx)
AU (2) AU7807301A (xx)
BG (1) BG107502A (xx)
BR (1) BR0113140A (xx)
CA (1) CA2417636A1 (xx)
CY (1) CY1105321T1 (xx)
DE (1) DE60120986T2 (xx)
DK (1) DK1305047T3 (xx)
EE (1) EE200300047A (xx)
ES (1) ES2261447T3 (xx)
HR (1) HRP20030121A2 (xx)
HU (1) HUP0300686A3 (xx)
IL (1) IL153933A0 (xx)
LV (1) LV13033B (xx)
MX (1) MXPA03000836A (xx)
NO (1) NO20030475L (xx)
NZ (1) NZ523688A (xx)
PL (1) PL364521A1 (xx)
PT (1) PT1305047E (xx)
SI (1) SI21123A (xx)
SK (1) SK1222003A3 (xx)
WO (1) WO2002009762A2 (xx)
YU (1) YU6703A (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0413846A (pt) * 2003-08-22 2006-10-24 Schering Aktiengellschaft derivados de piperazina inibidores de quimiocina e seu uso para tratar miocardite
US7917195B2 (en) 2004-03-05 2011-03-29 Lifesciences Solutions LLC Systems, methods and computer program products for heart monitoring
US10499828B2 (en) * 2004-03-05 2019-12-10 Lifescience Solutions, Llc System and method for heart monitoring
US8103065B2 (en) * 2006-01-05 2012-01-24 Lifescience Solutions Llc Assessment of medical conditions
US20110009758A1 (en) * 2009-07-10 2011-01-13 Lifescience Solutions Llc System and method for heart monitoring

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6323206B1 (en) 1996-07-12 2001-11-27 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
DE69840519D1 (de) 1997-02-26 2009-03-19 Pfizer Heteroaryl-hexansäureamid-derivate, ihre herstellung und ihre verwendung als selektive inhibitoren der bindung von mip-1-alpha an seinen ccr1 rezeptor
US6207665B1 (en) 1997-06-12 2001-03-27 Schering Aktiengesellschaft Piperazine derivatives and their use as anti-inflammatory agents
EP1049700B9 (en) 1998-01-21 2006-05-10 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
JP2002501052A (ja) 1998-01-21 2002-01-15 ミレニアム・ファーマシューティカルズ・インコーポレイテッド ケモカイン受容体アンタゴニストおよびその使用方法
IL137330A0 (en) 1998-02-05 2001-07-24 Pfizer Prod Inc Novel dihydroxyhexanoic acid derivatives
EP1000626A1 (en) 1998-09-18 2000-05-17 Applied Research Systems ARS Holding N.V. Chemokine receptor antagonist and cyclosporin in combined therapy
JP2002535358A (ja) 1999-01-29 2002-10-22 ミレニアム・ファーマシューティカルズ・インコーポレイテッド 移植片拒絶反応及び虚血−再灌流障害の予防方法

Also Published As

Publication number Publication date
DK1305047T3 (da) 2006-10-23
KR20030048000A (ko) 2003-06-18
HUP0300686A2 (hu) 2003-08-28
EP1305047A2 (en) 2003-05-02
CN1655818A (zh) 2005-08-17
MXPA03000836A (es) 2003-06-06
DE60120986D1 (de) 2006-08-03
ES2261447T3 (es) 2006-11-16
PT1305047E (pt) 2006-11-30
CA2417636A1 (en) 2002-02-07
BR0113140A (pt) 2003-06-24
SK1222003A3 (en) 2003-09-11
SI21123A (sl) 2003-08-31
ATE330634T1 (de) 2006-07-15
NO20030475D0 (no) 2003-01-30
PL364521A1 (en) 2004-12-13
EP1305047B1 (en) 2006-06-21
CY1105321T1 (el) 2010-03-03
WO2002009762A2 (en) 2002-02-07
EE200300047A (et) 2004-10-15
IL153933A0 (en) 2003-07-31
AU2001278073B2 (en) 2005-06-30
NO20030475L (no) 2003-03-28
NZ523688A (en) 2005-04-29
YU6703A (sh) 2006-05-25
HRP20030121A2 (en) 2005-02-28
JP2004530630A (ja) 2004-10-07
US6740636B2 (en) 2004-05-25
US20020039997A1 (en) 2002-04-04
AU7807301A (en) 2002-02-13
LV13033B (en) 2004-02-20
DE60120986T2 (de) 2006-11-23
WO2002009762A3 (en) 2003-01-09
HUP0300686A3 (en) 2005-03-29

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