DK1294888T3 - Interferonlignende protein Zcyto21 - Google Patents
Interferonlignende protein Zcyto21Info
- Publication number
- DK1294888T3 DK1294888T3 DK01950827T DK01950827T DK1294888T3 DK 1294888 T3 DK1294888 T3 DK 1294888T3 DK 01950827 T DK01950827 T DK 01950827T DK 01950827 T DK01950827 T DK 01950827T DK 1294888 T3 DK1294888 T3 DK 1294888T3
- Authority
- DK
- Denmark
- Prior art keywords
- amino acid
- zcyto21
- interferon
- acid sequence
- genetically engineered
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 238000011813 knockout mouse model Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000011830 transgenic mouse model Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21544600P | 2000-06-30 | 2000-06-30 | |
US28542401P | 2001-04-20 | 2001-04-20 | |
PCT/US2001/021087 WO2002002627A2 (fr) | 2000-06-30 | 2001-06-29 | Proteine zcyto21de type interferon |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1294888T3 true DK1294888T3 (da) | 2007-08-20 |
Family
ID=26910034
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01950827T DK1294888T3 (da) | 2000-06-30 | 2001-06-29 | Interferonlignende protein Zcyto21 |
DK06012489T DK1717316T3 (da) | 2000-06-30 | 2001-06-29 | Allelisk variant af interferon-lignende protein Zcyto21 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06012489T DK1717316T3 (da) | 2000-06-30 | 2001-06-29 | Allelisk variant af interferon-lignende protein Zcyto21 |
Country Status (13)
Country | Link |
---|---|
US (18) | US6927040B2 (fr) |
EP (4) | EP2132984A3 (fr) |
JP (1) | JP4377126B2 (fr) |
CN (1) | CN100448993C (fr) |
AT (2) | ATE360696T1 (fr) |
AU (1) | AU2001271786A1 (fr) |
BR (1) | BR0112119A (fr) |
CA (1) | CA2413258C (fr) |
DE (2) | DE60128093T2 (fr) |
DK (2) | DK1294888T3 (fr) |
ES (2) | ES2286128T3 (fr) |
RU (1) | RU2292394C2 (fr) |
WO (1) | WO2002002627A2 (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100448993C (zh) * | 2000-06-30 | 2009-01-07 | 津莫吉尼蒂克斯公司 | 干扰素样蛋白质Zcyto21 |
US7910313B2 (en) | 2001-04-20 | 2011-03-22 | Zymogenetics, Inc. | Cytokine protein family |
US7038032B2 (en) * | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
JP2004535795A (ja) * | 2001-05-10 | 2004-12-02 | イミュネックス・コーポレーション | サイトカインポリペプチド群 |
US6902930B2 (en) * | 2001-08-29 | 2005-06-07 | Vanderbilt University | Human Mob-5 (IL-24) receptors and uses thereof |
AU2003215136A1 (en) | 2002-02-08 | 2003-09-02 | University Of Medicine And Dentistry Of New Jersey | Ifn-a/b-independent mechanism of antiviral protection |
JP4409962B2 (ja) | 2002-04-19 | 2010-02-03 | ザイモジェネティクス,インコーポレイティド | サイトカイン受容体 |
JP2005534330A (ja) * | 2002-08-07 | 2005-11-17 | デルタ バイオテクノロジー リミテッド | アルブミン融合繊毛様神経栄養因子 |
JP2006509041A (ja) | 2002-10-23 | 2006-03-16 | ザイモジェネティクス,インコーポレイティド | Il−28およびil−29を用いるウイルス感染を治療するための方法 |
DK1668031T3 (da) | 2003-08-07 | 2008-06-30 | Zymogenetics Inc | Homogene præparater af IL-29 |
US20050244423A1 (en) * | 2004-04-02 | 2005-11-03 | Klucher Kevin M | Methods for treating viral infection using IL-28 and IL-29 cysteine mutants |
US7351689B2 (en) * | 2004-07-29 | 2008-04-01 | Zymogenetics, Inc. | Use of IL-28 and IL-29 to treat cancer and autoimmune disorders |
US20060178301A1 (en) * | 2005-02-04 | 2006-08-10 | Mathias Jurs | Albumin-fused ciliary neurotrophic factor |
JP2009502803A (ja) * | 2005-07-20 | 2009-01-29 | ザイモジェネティクス, インコーポレイテッド | Il−28およびil−29のシステイン欠失変異体、ならびにそれを用いる抗ウイルス法 |
JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
SI1931704T1 (sl) | 2005-10-04 | 2011-04-29 | Zymogenetics L L C | Priprava in čiščenje IL-29 |
TW200744634A (en) * | 2006-02-21 | 2007-12-16 | Wyeth Corp | Methods of using antibodies against human IL-22 |
CA2910933C (fr) | 2007-12-07 | 2017-04-11 | Zymogenetics, Inc. | Anticorps monoclonaux anti-il-21 humain |
CN105535961A (zh) * | 2008-04-04 | 2016-05-04 | 宾夕法尼亚大学托管会 | 使用il-28和组合物的疫苗和免疫治疗及其使用方法 |
CN103536906A (zh) * | 2008-06-05 | 2014-01-29 | 津莫吉尼蒂克斯公司 | 利用聚乙二醇化的iii 型干扰素治疗丙型肝炎 |
WO2010045261A1 (fr) * | 2008-10-13 | 2010-04-22 | Zymogenetics, Llc | Interférons de type iii à fc de chaîne unique et leurs procédés d'utilisation |
EP2563720A1 (fr) | 2010-04-28 | 2013-03-06 | Murata Manufacturing Co., Ltd. | Matériau de perovskite avec propriétés diélectriques contrôlées par anion, dispositif de condensateur à couche mince, et procédé pour fabriquer celui-ci |
FR2975185A1 (fr) * | 2011-05-12 | 2012-11-16 | Univ Claude Bernard Lyon | Procede de determination in vitro de la presence d'une sclerose en plaques |
RU2549710C2 (ru) * | 2012-06-29 | 2015-04-27 | Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) | Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа |
CN102998450B (zh) * | 2012-11-22 | 2014-10-15 | 北京正旦国际科技有限责任公司 | 一种食管癌免疫质谱检测试剂盒的制备方法 |
CN104968673B (zh) | 2014-01-08 | 2018-11-02 | 德益阳光生物技术(北京)有限责任公司 | 融合多肽及使用方法 |
US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
CN107530338B (zh) | 2015-04-21 | 2020-12-01 | 艾格尔峰生物制药有限公司 | 包含洛那法尼和利托那韦的药物组合物 |
US10953072B2 (en) | 2016-02-19 | 2021-03-23 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection with interferon lambda |
AU2017336078B2 (en) * | 2016-09-30 | 2022-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Variant type III interferons and synthekines |
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CN100448993C (zh) | 2000-06-30 | 2009-01-07 | 津莫吉尼蒂克斯公司 | 干扰素样蛋白质Zcyto21 |
WO2002068579A2 (fr) * | 2001-01-10 | 2002-09-06 | Pe Corporation (Ny) | Kits tels que des dosages d'acides nucleiques comprenant une majorite d'exons ou de transcrits humains, destines a detecter l'expression et pouvant avoir d'autres applications |
US7038032B2 (en) | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
JP2004535795A (ja) | 2001-05-10 | 2004-12-02 | イミュネックス・コーポレーション | サイトカインポリペプチド群 |
JP3939160B2 (ja) * | 2001-05-25 | 2007-07-04 | 独立行政法人科学技術振興機構 | 腎臓における外来遺伝子発現方法 |
AU2003215136A1 (en) | 2002-02-08 | 2003-09-02 | University Of Medicine And Dentistry Of New Jersey | Ifn-a/b-independent mechanism of antiviral protection |
JP2006509041A (ja) | 2002-10-23 | 2006-03-16 | ザイモジェネティクス,インコーポレイティド | Il−28およびil−29を用いるウイルス感染を治療するための方法 |
DK1668031T3 (da) | 2003-08-07 | 2008-06-30 | Zymogenetics Inc | Homogene præparater af IL-29 |
US20050244423A1 (en) | 2004-04-02 | 2005-11-03 | Klucher Kevin M | Methods for treating viral infection using IL-28 and IL-29 cysteine mutants |
JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
CN103536906A (zh) | 2008-06-05 | 2014-01-29 | 津莫吉尼蒂克斯公司 | 利用聚乙二醇化的iii 型干扰素治疗丙型肝炎 |
WO2010045261A1 (fr) | 2008-10-13 | 2010-04-22 | Zymogenetics, Llc | Interférons de type iii à fc de chaîne unique et leurs procédés d'utilisation |
-
2001
- 2001-06-29 CN CNB018131530A patent/CN100448993C/zh not_active Ceased
- 2001-06-29 JP JP2002507878A patent/JP4377126B2/ja not_active Expired - Lifetime
- 2001-06-29 DE DE60128093T patent/DE60128093T2/de not_active Expired - Lifetime
- 2001-06-29 EP EP09172071A patent/EP2132984A3/fr not_active Withdrawn
- 2001-06-29 WO PCT/US2001/021087 patent/WO2002002627A2/fr active IP Right Grant
- 2001-06-29 CA CA2413258A patent/CA2413258C/fr not_active Expired - Lifetime
- 2001-06-29 DK DK01950827T patent/DK1294888T3/da active
- 2001-06-29 ES ES01950827T patent/ES2286128T3/es not_active Expired - Lifetime
- 2001-06-29 AT AT01950827T patent/ATE360696T1/de active
- 2001-06-29 BR BR0112119-7A patent/BR0112119A/pt active Search and Examination
- 2001-06-29 DK DK06012489T patent/DK1717316T3/da active
- 2001-06-29 EP EP01950827A patent/EP1294888B1/fr not_active Expired - Lifetime
- 2001-06-29 ES ES06012489T patent/ES2311253T3/es not_active Expired - Lifetime
- 2001-06-29 DE DE60135393T patent/DE60135393D1/de not_active Expired - Lifetime
- 2001-06-29 EP EP08100616A patent/EP1939293A3/fr not_active Withdrawn
- 2001-06-29 AU AU2001271786A patent/AU2001271786A1/en not_active Abandoned
- 2001-06-29 AT AT06012489T patent/ATE404670T1/de active
- 2001-06-29 US US09/895,834 patent/US6927040B2/en not_active Expired - Lifetime
- 2001-06-29 RU RU2003103099/13A patent/RU2292394C2/ru active
- 2001-06-29 EP EP06012489A patent/EP1717316B1/fr not_active Expired - Lifetime
-
2004
- 2004-03-02 US US10/790,996 patent/US20040146988A1/en not_active Abandoned
- 2004-08-27 US US10/927,891 patent/US7252969B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/928,539 patent/US7241870B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/927,815 patent/US7253261B2/en not_active Expired - Lifetime
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2006
- 2006-10-10 US US11/548,056 patent/US7485700B2/en not_active Expired - Lifetime
- 2006-10-10 US US11/548,023 patent/US7445913B2/en not_active Expired - Lifetime
- 2006-10-10 US US11/548,138 patent/US20070049736A1/en not_active Abandoned
- 2006-10-10 US US11/548,108 patent/US20070043209A1/en not_active Abandoned
-
2007
- 2007-10-16 US US11/873,272 patent/US7655223B2/en not_active Expired - Lifetime
- 2007-10-26 US US11/925,097 patent/US7498154B2/en not_active Expired - Lifetime
-
2008
- 2008-01-09 US US11/971,624 patent/US20080214788A1/en not_active Abandoned
- 2008-12-22 US US12/341,273 patent/US20090326204A1/en not_active Abandoned
-
2009
- 2009-11-30 US US12/628,078 patent/US7833520B2/en not_active Expired - Fee Related
-
2010
- 2010-09-30 US US12/895,139 patent/US7919595B2/en not_active Expired - Fee Related
-
2011
- 2011-03-02 US US13/039,223 patent/US20110172170A1/en not_active Abandoned
- 2011-09-08 US US13/227,548 patent/US20120036590A1/en not_active Abandoned
-
2012
- 2012-05-03 US US13/463,046 patent/US20120258458A1/en not_active Abandoned
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