BR0112119A - Polipeptìdeo isolado, molécula de ácido nucléico isolado, vetor, célula hospedeira recombinante, método de produzir a proteìna zcyto21, anticorpo ou fragmento de anticorpo, método de detectar a presença da expressão do gene zcyto21 em uma amostra biológica - Google Patents

Polipeptìdeo isolado, molécula de ácido nucléico isolado, vetor, célula hospedeira recombinante, método de produzir a proteìna zcyto21, anticorpo ou fragmento de anticorpo, método de detectar a presença da expressão do gene zcyto21 em uma amostra biológica

Info

Publication number
BR0112119A
BR0112119A BR0112119-7A BR0112119A BR0112119A BR 0112119 A BR0112119 A BR 0112119A BR 0112119 A BR0112119 A BR 0112119A BR 0112119 A BR0112119 A BR 0112119A
Authority
BR
Brazil
Prior art keywords
zcyto21
antibody
vector
nucleic acid
protein
Prior art date
Application number
BR0112119-7A
Other languages
English (en)
Inventor
Paul O Sheppard
Scott R Presnell
Brian A Fox
Teresa Gilbert
Betty A Haldeman
Francis J Grant
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26910034&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0112119(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of BR0112119A publication Critical patent/BR0112119A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Abstract

"POLIPEPTìDEO ISOLADO, MOLéCULA DE áCIDO NUCLéICO ISOLADO, VETOR, CéLULA HOSPEDEIRA RECOMBINANTE, MéTODO DE PRODUZIR A PROTEìNA ZCYTO21, ANTICORPO OU FRAGMENTO DE ANTICORPO, MéTODO DE DETECTAR A PRESENçA DA EXPRESSãO DO GENE ZCYTO21 EM UMA AMOSTRA BIOLóGICA". A presente invenção diz respeito a moléculas de polinucleotídeo e polipeptídeo para Zcyto21, uma proteína semelhante ao interferon, que é mais intimamente relacionada com o interferon-<244> ao nível da seq³ência de aminoácido. A presente invenção também inclui anticorpos para os polipeptídeos Zcyto21, e métodos de usar os polinucleotídeos e polipeptídeos.
BR0112119-7A 2000-06-30 2001-06-29 Polipeptìdeo isolado, molécula de ácido nucléico isolado, vetor, célula hospedeira recombinante, método de produzir a proteìna zcyto21, anticorpo ou fragmento de anticorpo, método de detectar a presença da expressão do gene zcyto21 em uma amostra biológica BR0112119A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21544600P 2000-06-30 2000-06-30
US28542401P 2001-04-20 2001-04-20
PCT/US2001/021087 WO2002002627A2 (en) 2000-06-30 2001-06-29 Interferon-like protein zcyto21

Publications (1)

Publication Number Publication Date
BR0112119A true BR0112119A (pt) 2003-05-06

Family

ID=26910034

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0112119-7A BR0112119A (pt) 2000-06-30 2001-06-29 Polipeptìdeo isolado, molécula de ácido nucléico isolado, vetor, célula hospedeira recombinante, método de produzir a proteìna zcyto21, anticorpo ou fragmento de anticorpo, método de detectar a presença da expressão do gene zcyto21 em uma amostra biológica

Country Status (13)

Country Link
US (18) US6927040B2 (pt)
EP (4) EP1294888B1 (pt)
JP (1) JP4377126B2 (pt)
CN (1) CN100448993C (pt)
AT (2) ATE404670T1 (pt)
AU (1) AU2001271786A1 (pt)
BR (1) BR0112119A (pt)
CA (1) CA2413258C (pt)
DE (2) DE60128093T2 (pt)
DK (2) DK1717316T3 (pt)
ES (2) ES2286128T3 (pt)
RU (1) RU2292394C2 (pt)
WO (1) WO2002002627A2 (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1294888B1 (en) * 2000-06-30 2007-04-25 ZymoGenetics, Inc. Interferon-like protein zcyto21
US7910313B2 (en) 2001-04-20 2011-03-22 Zymogenetics, Inc. Cytokine protein family
US7038032B2 (en) * 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
CA2446180A1 (en) * 2001-05-10 2002-11-21 Immunex Corporation Cytokine polypeptides
WO2003029262A2 (en) * 2001-08-29 2003-04-10 Vanderbilt University The human mob-5 (il-24) receptors and uses thereof
AU2003215136A1 (en) 2002-02-08 2003-09-02 University Of Medicine And Dentistry Of New Jersey Ifn-a/b-independent mechanism of antiviral protection
EP1497415B1 (en) 2002-04-19 2010-12-29 ZymoGenetics, L.L.C. Methods for detection or modulation of the interaction of a cytokine receptor with its ligand
EP1529108A2 (en) * 2002-08-07 2005-05-11 ZLB Behring GmbH Albumin-fused ciliary neurotrophic factor
WO2004037995A2 (en) * 2002-10-23 2004-05-06 Zymogenetics, Inc. Methods for treating viral infection using il-28 and il-29
ATE388963T1 (de) * 2003-08-07 2008-03-15 Zymogenetics Inc Homogene herstellungen von il-29
WO2005097165A2 (en) 2004-04-02 2005-10-20 Zymogenetics, Inc. Il-28 and il-29 cysteine mutants for treating viral infection
WO2006012644A2 (en) * 2004-07-29 2006-02-02 Zymogenetics, Inc. Use of il-28 and il-29 to treat cancer
US20060178301A1 (en) * 2005-02-04 2006-08-10 Mathias Jurs Albumin-fused ciliary neurotrophic factor
JP4987001B2 (ja) * 2005-07-20 2012-07-25 ザイモジェネティクス リミテッド ライアビリティ カンパニー 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法
CA2616122A1 (en) * 2005-07-20 2007-01-25 Zymogenetics, Inc. Il28 and il29 truncated cysteine mutants and antiviral methods of using same
CA2625208A1 (en) * 2005-10-04 2007-04-12 Zymogenetics, Inc. Production and purification of il-29
TW200744634A (en) * 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
AU2008364115B2 (en) 2007-12-07 2013-11-21 Zymogenetics, Inc. Anti-human IL-21 monoclonal antibodies
WO2009124309A2 (en) 2008-04-04 2009-10-08 The Trustees Of The University Of Pennsylvania Vaccines and immunotherapeutics using il-28 and compositions and methods of using the same
CA2727026A1 (en) * 2008-06-05 2009-12-10 Zymogenetics, Llc Use of pegylated type iii interferons for the treatment of hepatitis c
EP2344546A1 (en) * 2008-10-13 2011-07-20 Zymogenetics, Inc. Single chain fc type iii interferons and methods of using same
WO2011135439A1 (en) 2010-04-28 2011-11-03 Murata Manufacturing Co., Ltd. Perovskite material with anion-controlled dielectric properties, thin film capacitor device, and method for manufacturing the same
FR2975185A1 (fr) * 2011-05-12 2012-11-16 Univ Claude Bernard Lyon Procede de determination in vitro de la presence d'une sclerose en plaques
RU2549710C2 (ru) * 2012-06-29 2015-04-27 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа
CN102998450B (zh) * 2012-11-22 2014-10-15 北京正旦国际科技有限责任公司 一种食管癌免疫质谱检测试剂盒的制备方法
EP3954714A1 (en) 2014-01-08 2022-02-16 Prosit Sole Biotechnology (Beijing) Co. Ltd Fusion polypeptides and methods of use
US11311519B2 (en) 2014-05-01 2022-04-26 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
US10076512B2 (en) 2014-05-01 2018-09-18 Eiger Biopharmaceuticals, Inc. Treatment of hepatitis delta virus infection
KR102514971B1 (ko) 2015-04-21 2023-03-27 아이거 바이오파마슈티컬스 인코포레이티드 로나파르닙 및 리토나버를 포함하는 약제 조성물
PL3416675T3 (pl) 2016-02-19 2021-10-11 Eiger Biopharmaceuticals, Inc. Leczenie zakażenia wirusem zapalenia wątroby typu delta za pomocą interferonu lambda
MX2019003744A (es) * 2016-09-30 2019-10-30 Univ Leland Stanford Junior Interferones de variante tipo iii y sintecinas.

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3000213A1 (de) 1980-01-04 1981-07-09 Zahnfabrik Wienand Söhne & Co GmbH, 6072 Dreieich Verfahren zur herstellung eines vernetzten polymerisatz fuer dentalzwecke
ES498343A0 (es) * 1980-01-08 1983-09-01 Biogen Nv Un metodo de producir un polipeptido que exhibe actividad inmunologica o biologica del interferon de leucocitos humanos.
US4615974A (en) 1981-08-25 1986-10-07 Celltech Limited Yeast expression vectors
US4579821A (en) 1981-11-23 1986-04-01 University Patents, Inc. Control of DNA sequence transcription
US4656134A (en) 1982-01-11 1987-04-07 Board Of Trustees Of Leland Stanford Jr. University Gene amplification in eukaryotic cells
US4486533A (en) 1982-09-02 1984-12-04 St. Louis University Filamentous fungi functional replicating extrachromosomal element
US4599311A (en) 1982-08-13 1986-07-08 Kawasaki Glenn H Glycolytic promotersfor regulated protein expression: protease inhibitor
US4977092A (en) 1985-06-26 1990-12-11 Amgen Expression of exogenous polypeptides and polypeptide products including hepatitis B surface antigen in yeast cells
US4601978A (en) 1982-11-24 1986-07-22 The Regents Of The University Of California Mammalian metallothionein promoter system
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
US4661454A (en) 1983-02-28 1987-04-28 Collaborative Research, Inc. GAL1 yeast promoter linked to non galactokinase gene
US5139936A (en) 1983-02-28 1992-08-18 Collaborative Research, Inc. Use of the GAL1 yeast promoter
US4870008A (en) 1983-08-12 1989-09-26 Chiron Corporation Secretory expression in eukaryotes
US4496778A (en) * 1983-10-03 1985-01-29 Exxon Research & Engineering Co. Process for the hydroxylation of olefins using molecular oxygen, an osmium containing catalyst, a copper Co-catalyst, and an aromatic amine based promoter
US4931373A (en) 1984-05-25 1990-06-05 Zymogenetics, Inc. Stable DNA constructs for expression of α-1 antitrypsin
US4766073A (en) 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
ATE54167T1 (de) 1984-12-06 1990-07-15 Fina Research Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden.
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GR860984B (en) 1985-04-17 1986-08-18 Zymogenetics Inc Expression of factor vii and ix activities in mammalian cells
US4882279A (en) 1985-10-25 1989-11-21 Phillips Petroleum Company Site selective genomic modification of yeast of the genus pichia
US4935349A (en) 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus
GB8611832D0 (en) 1986-05-15 1986-06-25 Holland I B Polypeptide
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5063154A (en) 1987-06-24 1991-11-05 Whitehead Institute For Biomedical Research Pheromone - inducible yeast promoter
US4956288A (en) 1988-04-22 1990-09-11 Biogen, Inc. Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
US5162228A (en) 1988-12-28 1992-11-10 Takeda Chemical Industries, Ltd. Gylceraldehyde-3-phosphate dehydrogenase gene and promoter
US5298418A (en) 1991-09-16 1994-03-29 Boyce Thompson Institute For Plant Research, Inc. Cell line isolated from larval midgut tissue of Trichoplusia ni
US5565332A (en) * 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5700638A (en) * 1993-08-26 1997-12-23 Washington University Cell death regulator
CA2183266A1 (en) 1994-02-14 1995-08-17 Richard D. Holly Hematopoietic protein and materials and methods for making it
US6451578B1 (en) * 1994-02-14 2002-09-17 Abbott Laboratories Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use
US5641655A (en) 1994-11-30 1997-06-24 Zymogenetics, Inc. Methods for producing thrombopoietin polypeptides using a mammalian tissue plasminogen activator secretory peptide
US5679715A (en) 1995-06-07 1997-10-21 Harris; Richard Y. Method for treating multiple sclerosis
US5955349A (en) 1996-08-26 1999-09-21 Zymogenetics, Inc. Compositions and methods for producing heterologous polypeptides in Pichia methanolica
US5716808A (en) 1995-11-09 1998-02-10 Zymogenetics, Inc. Genetic engineering of pichia methanolica
US6025539A (en) * 1996-04-09 2000-02-15 Mayo Foundation For Medical Education And Research IL-5 transgenic mouse
TW517067B (en) 1996-05-31 2003-01-11 Hoffmann La Roche Interferon conjugates
AU3721397A (en) * 1996-07-09 1998-02-02 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
US5736383A (en) 1996-08-26 1998-04-07 Zymogenetics, Inc. Preparation of Pichia methanolica auxotrophic mutants
CN1230997A (zh) 1996-07-17 1999-10-06 津莫吉尼蒂克斯公司 甲醇毕赤酵母的转化
US5985614A (en) 1996-08-30 1999-11-16 Human Genome Sciences, Inc. Polynucleotides encoding interleukin-19
EP1500329B1 (en) 1996-12-03 2012-03-21 Amgen Fremont Inc. Human antibodies that specifically bind human TNF alpha
GB9702944D0 (en) * 1997-02-13 1997-04-02 Univ Manchester Reducing fibrosis
US5945511A (en) 1997-02-20 1999-08-31 Zymogenetics, Inc. Class II cytokine receptor
US5965704A (en) 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
AU2871899A (en) 1998-03-09 1999-09-27 Schering Corporation Human receptor proteins; related reagents and methods
US6143503A (en) * 1998-04-17 2000-11-07 Whitehead Institute For Biomedical Research Use of a ribozyme to join nucleic acids and peptides
AU2157000A (en) * 1998-12-18 2000-07-12 Schering Corporation Ribavirin-pegylated interferon alfa induction hcv combination therapy
AU2158000A (en) * 1998-12-22 2000-07-12 Schering Corporation Treatment of hepatitis c virus infections with interleukin-10
EP1294888B1 (en) 2000-06-30 2007-04-25 ZymoGenetics, Inc. Interferon-like protein zcyto21
AU2002255478A1 (en) * 2001-01-10 2002-09-12 Pe Corporation (Ny) Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof
US7038032B2 (en) 2001-04-20 2006-05-02 Zymogenetics, Inc. Cytokine protein family
CA2446180A1 (en) 2001-05-10 2002-11-21 Immunex Corporation Cytokine polypeptides
JP3939160B2 (ja) * 2001-05-25 2007-07-04 独立行政法人科学技術振興機構 腎臓における外来遺伝子発現方法
AU2003215136A1 (en) 2002-02-08 2003-09-02 University Of Medicine And Dentistry Of New Jersey Ifn-a/b-independent mechanism of antiviral protection
WO2004037995A2 (en) 2002-10-23 2004-05-06 Zymogenetics, Inc. Methods for treating viral infection using il-28 and il-29
ATE388963T1 (de) 2003-08-07 2008-03-15 Zymogenetics Inc Homogene herstellungen von il-29
WO2005097165A2 (en) 2004-04-02 2005-10-20 Zymogenetics, Inc. Il-28 and il-29 cysteine mutants for treating viral infection
JP4987001B2 (ja) * 2005-07-20 2012-07-25 ザイモジェネティクス リミテッド ライアビリティ カンパニー 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法
CA2727026A1 (en) 2008-06-05 2009-12-10 Zymogenetics, Llc Use of pegylated type iii interferons for the treatment of hepatitis c
EP2344546A1 (en) 2008-10-13 2011-07-20 Zymogenetics, Inc. Single chain fc type iii interferons and methods of using same

Also Published As

Publication number Publication date
RU2003103099A (ru) 2005-01-20
US20050014228A1 (en) 2005-01-20
US7655223B2 (en) 2010-02-02
EP1717316B1 (en) 2008-08-13
US20070043209A1 (en) 2007-02-22
US20070049736A1 (en) 2007-03-01
US20070048841A1 (en) 2007-03-01
CN1443240A (zh) 2003-09-17
CA2413258C (en) 2012-01-03
ES2311253T3 (es) 2009-02-01
US7498154B2 (en) 2009-03-03
US20120258458A1 (en) 2012-10-11
EP1939293A3 (en) 2008-07-09
CN100448993C (zh) 2009-01-07
EP2132984A2 (en) 2009-12-16
AU2001271786A1 (en) 2002-01-14
DK1294888T3 (da) 2007-08-20
US7241870B2 (en) 2007-07-10
DK1717316T3 (da) 2008-12-08
US6927040B2 (en) 2005-08-09
US20110172170A1 (en) 2011-07-14
US20050106680A1 (en) 2005-05-19
US20110054148A1 (en) 2011-03-03
EP1294888B1 (en) 2007-04-25
RU2292394C2 (ru) 2007-01-27
WO2002002627A2 (en) 2002-01-10
WO2002002627A3 (en) 2003-01-03
US20040146988A1 (en) 2004-07-29
US20020039763A1 (en) 2002-04-04
ATE404670T1 (de) 2008-08-15
US20080102490A1 (en) 2008-05-01
JP2004502419A (ja) 2004-01-29
US20080214788A1 (en) 2008-09-04
DE60135393D1 (de) 2008-09-25
ES2286128T3 (es) 2007-12-01
DE60128093T2 (de) 2007-12-27
JP4377126B2 (ja) 2009-12-02
US7253261B2 (en) 2007-08-07
US7445913B2 (en) 2008-11-04
EP1294888A2 (en) 2003-03-26
US7833520B2 (en) 2010-11-16
EP2132984A3 (en) 2010-11-03
US20100222266A1 (en) 2010-09-02
US20050106682A1 (en) 2005-05-19
US20090326204A1 (en) 2009-12-31
EP1717316A1 (en) 2006-11-02
EP1939293A2 (en) 2008-07-02
CA2413258A1 (en) 2002-01-10
US7485700B2 (en) 2009-02-03
US20120036590A1 (en) 2012-02-09
US7252969B2 (en) 2007-08-07
US20070042468A1 (en) 2007-02-22
ATE360696T1 (de) 2007-05-15
US20090069274A1 (en) 2009-03-12
DE60128093D1 (de) 2007-06-06
US7919595B2 (en) 2011-04-05

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