BR0112119A - Polipeptìdeo isolado, molécula de ácido nucléico isolado, vetor, célula hospedeira recombinante, método de produzir a proteìna zcyto21, anticorpo ou fragmento de anticorpo, método de detectar a presença da expressão do gene zcyto21 em uma amostra biológica - Google Patents
Polipeptìdeo isolado, molécula de ácido nucléico isolado, vetor, célula hospedeira recombinante, método de produzir a proteìna zcyto21, anticorpo ou fragmento de anticorpo, método de detectar a presença da expressão do gene zcyto21 em uma amostra biológicaInfo
- Publication number
- BR0112119A BR0112119A BR0112119-7A BR0112119A BR0112119A BR 0112119 A BR0112119 A BR 0112119A BR 0112119 A BR0112119 A BR 0112119A BR 0112119 A BR0112119 A BR 0112119A
- Authority
- BR
- Brazil
- Prior art keywords
- zcyto21
- antibody
- vector
- nucleic acid
- protein
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 102000008394 Immunoglobulin Fragments Human genes 0.000 title 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 title 1
- 239000012472 biological sample Substances 0.000 title 1
- 230000014509 gene expression Effects 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 101100232735 Homo sapiens IFNL1 gene Proteins 0.000 abstract 1
- 102100020990 Interferon lambda-1 Human genes 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Abstract
"POLIPEPTìDEO ISOLADO, MOLéCULA DE áCIDO NUCLéICO ISOLADO, VETOR, CéLULA HOSPEDEIRA RECOMBINANTE, MéTODO DE PRODUZIR A PROTEìNA ZCYTO21, ANTICORPO OU FRAGMENTO DE ANTICORPO, MéTODO DE DETECTAR A PRESENçA DA EXPRESSãO DO GENE ZCYTO21 EM UMA AMOSTRA BIOLóGICA". A presente invenção diz respeito a moléculas de polinucleotídeo e polipeptídeo para Zcyto21, uma proteína semelhante ao interferon, que é mais intimamente relacionada com o interferon-<244> ao nível da seq³ência de aminoácido. A presente invenção também inclui anticorpos para os polipeptídeos Zcyto21, e métodos de usar os polinucleotídeos e polipeptídeos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21544600P | 2000-06-30 | 2000-06-30 | |
US28542401P | 2001-04-20 | 2001-04-20 | |
PCT/US2001/021087 WO2002002627A2 (en) | 2000-06-30 | 2001-06-29 | Interferon-like protein zcyto21 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0112119A true BR0112119A (pt) | 2003-05-06 |
Family
ID=26910034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0112119-7A BR0112119A (pt) | 2000-06-30 | 2001-06-29 | Polipeptìdeo isolado, molécula de ácido nucléico isolado, vetor, célula hospedeira recombinante, método de produzir a proteìna zcyto21, anticorpo ou fragmento de anticorpo, método de detectar a presença da expressão do gene zcyto21 em uma amostra biológica |
Country Status (13)
Country | Link |
---|---|
US (18) | US6927040B2 (pt) |
EP (4) | EP1294888B1 (pt) |
JP (1) | JP4377126B2 (pt) |
CN (1) | CN100448993C (pt) |
AT (2) | ATE404670T1 (pt) |
AU (1) | AU2001271786A1 (pt) |
BR (1) | BR0112119A (pt) |
CA (1) | CA2413258C (pt) |
DE (2) | DE60128093T2 (pt) |
DK (2) | DK1717316T3 (pt) |
ES (2) | ES2286128T3 (pt) |
RU (1) | RU2292394C2 (pt) |
WO (1) | WO2002002627A2 (pt) |
Families Citing this family (31)
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EP1294888B1 (en) * | 2000-06-30 | 2007-04-25 | ZymoGenetics, Inc. | Interferon-like protein zcyto21 |
US7910313B2 (en) | 2001-04-20 | 2011-03-22 | Zymogenetics, Inc. | Cytokine protein family |
US7038032B2 (en) * | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
CA2446180A1 (en) * | 2001-05-10 | 2002-11-21 | Immunex Corporation | Cytokine polypeptides |
WO2003029262A2 (en) * | 2001-08-29 | 2003-04-10 | Vanderbilt University | The human mob-5 (il-24) receptors and uses thereof |
AU2003215136A1 (en) | 2002-02-08 | 2003-09-02 | University Of Medicine And Dentistry Of New Jersey | Ifn-a/b-independent mechanism of antiviral protection |
EP1497415B1 (en) | 2002-04-19 | 2010-12-29 | ZymoGenetics, L.L.C. | Methods for detection or modulation of the interaction of a cytokine receptor with its ligand |
EP1529108A2 (en) * | 2002-08-07 | 2005-05-11 | ZLB Behring GmbH | Albumin-fused ciliary neurotrophic factor |
WO2004037995A2 (en) * | 2002-10-23 | 2004-05-06 | Zymogenetics, Inc. | Methods for treating viral infection using il-28 and il-29 |
ATE388963T1 (de) * | 2003-08-07 | 2008-03-15 | Zymogenetics Inc | Homogene herstellungen von il-29 |
WO2005097165A2 (en) | 2004-04-02 | 2005-10-20 | Zymogenetics, Inc. | Il-28 and il-29 cysteine mutants for treating viral infection |
WO2006012644A2 (en) * | 2004-07-29 | 2006-02-02 | Zymogenetics, Inc. | Use of il-28 and il-29 to treat cancer |
US20060178301A1 (en) * | 2005-02-04 | 2006-08-10 | Mathias Jurs | Albumin-fused ciliary neurotrophic factor |
JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
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CA2625208A1 (en) * | 2005-10-04 | 2007-04-12 | Zymogenetics, Inc. | Production and purification of il-29 |
TW200744634A (en) * | 2006-02-21 | 2007-12-16 | Wyeth Corp | Methods of using antibodies against human IL-22 |
AU2008364115B2 (en) | 2007-12-07 | 2013-11-21 | Zymogenetics, Inc. | Anti-human IL-21 monoclonal antibodies |
WO2009124309A2 (en) | 2008-04-04 | 2009-10-08 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using il-28 and compositions and methods of using the same |
CA2727026A1 (en) * | 2008-06-05 | 2009-12-10 | Zymogenetics, Llc | Use of pegylated type iii interferons for the treatment of hepatitis c |
EP2344546A1 (en) * | 2008-10-13 | 2011-07-20 | Zymogenetics, Inc. | Single chain fc type iii interferons and methods of using same |
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FR2975185A1 (fr) * | 2011-05-12 | 2012-11-16 | Univ Claude Bernard Lyon | Procede de determination in vitro de la presence d'une sclerose en plaques |
RU2549710C2 (ru) * | 2012-06-29 | 2015-04-27 | Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) | Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа |
CN102998450B (zh) * | 2012-11-22 | 2014-10-15 | 北京正旦国际科技有限责任公司 | 一种食管癌免疫质谱检测试剂盒的制备方法 |
EP3954714A1 (en) | 2014-01-08 | 2022-02-16 | Prosit Sole Biotechnology (Beijing) Co. Ltd | Fusion polypeptides and methods of use |
US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
KR102514971B1 (ko) | 2015-04-21 | 2023-03-27 | 아이거 바이오파마슈티컬스 인코포레이티드 | 로나파르닙 및 리토나버를 포함하는 약제 조성물 |
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MX2019003744A (es) * | 2016-09-30 | 2019-10-30 | Univ Leland Stanford Junior | Interferones de variante tipo iii y sintecinas. |
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2001
- 2001-06-29 EP EP01950827A patent/EP1294888B1/en not_active Expired - Lifetime
- 2001-06-29 AT AT06012489T patent/ATE404670T1/de active
- 2001-06-29 EP EP08100616A patent/EP1939293A3/en not_active Withdrawn
- 2001-06-29 US US09/895,834 patent/US6927040B2/en not_active Expired - Lifetime
- 2001-06-29 DK DK06012489T patent/DK1717316T3/da active
- 2001-06-29 ES ES01950827T patent/ES2286128T3/es not_active Expired - Lifetime
- 2001-06-29 CA CA2413258A patent/CA2413258C/en not_active Expired - Lifetime
- 2001-06-29 CN CNB018131530A patent/CN100448993C/zh not_active Ceased
- 2001-06-29 DK DK01950827T patent/DK1294888T3/da active
- 2001-06-29 AU AU2001271786A patent/AU2001271786A1/en not_active Abandoned
- 2001-06-29 AT AT01950827T patent/ATE360696T1/de active
- 2001-06-29 EP EP06012489A patent/EP1717316B1/en not_active Expired - Lifetime
- 2001-06-29 ES ES06012489T patent/ES2311253T3/es not_active Expired - Lifetime
- 2001-06-29 WO PCT/US2001/021087 patent/WO2002002627A2/en active IP Right Grant
- 2001-06-29 DE DE60128093T patent/DE60128093T2/de not_active Expired - Lifetime
- 2001-06-29 DE DE60135393T patent/DE60135393D1/de not_active Expired - Lifetime
- 2001-06-29 JP JP2002507878A patent/JP4377126B2/ja not_active Expired - Lifetime
- 2001-06-29 EP EP09172071A patent/EP2132984A3/en not_active Withdrawn
- 2001-06-29 BR BR0112119-7A patent/BR0112119A/pt active Search and Examination
- 2001-06-29 RU RU2003103099/13A patent/RU2292394C2/ru active
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2004
- 2004-03-02 US US10/790,996 patent/US20040146988A1/en not_active Abandoned
- 2004-08-27 US US10/927,815 patent/US7253261B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/927,891 patent/US7252969B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/928,539 patent/US7241870B2/en not_active Expired - Lifetime
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2006
- 2006-10-10 US US11/548,023 patent/US7445913B2/en not_active Expired - Lifetime
- 2006-10-10 US US11/548,056 patent/US7485700B2/en not_active Expired - Lifetime
- 2006-10-10 US US11/548,108 patent/US20070043209A1/en not_active Abandoned
- 2006-10-10 US US11/548,138 patent/US20070049736A1/en not_active Abandoned
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2007
- 2007-10-16 US US11/873,272 patent/US7655223B2/en not_active Expired - Lifetime
- 2007-10-26 US US11/925,097 patent/US7498154B2/en not_active Expired - Lifetime
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2008
- 2008-01-09 US US11/971,624 patent/US20080214788A1/en not_active Abandoned
- 2008-12-22 US US12/341,273 patent/US20090326204A1/en not_active Abandoned
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2009
- 2009-11-30 US US12/628,078 patent/US7833520B2/en not_active Expired - Fee Related
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2010
- 2010-09-30 US US12/895,139 patent/US7919595B2/en not_active Expired - Fee Related
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2011
- 2011-03-02 US US13/039,223 patent/US20110172170A1/en not_active Abandoned
- 2011-09-08 US US13/227,548 patent/US20120036590A1/en not_active Abandoned
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2012
- 2012-05-03 US US13/463,046 patent/US20120258458A1/en not_active Abandoned
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