ATE360696T1 - Interferon-ähnliches protein zcyto21 - Google Patents
Interferon-ähnliches protein zcyto21Info
- Publication number
- ATE360696T1 ATE360696T1 AT01950827T AT01950827T ATE360696T1 AT E360696 T1 ATE360696 T1 AT E360696T1 AT 01950827 T AT01950827 T AT 01950827T AT 01950827 T AT01950827 T AT 01950827T AT E360696 T1 ATE360696 T1 AT E360696T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- zcyto21
- interferon
- acid sequence
- genetically engineered
- Prior art date
Links
- 101100232735 Homo sapiens IFNL1 gene Proteins 0.000 title 1
- 102100020990 Interferon lambda-1 Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 238000011813 knockout mouse model Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000011830 transgenic mouse model Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21544600P | 2000-06-30 | 2000-06-30 | |
US28542401P | 2001-04-20 | 2001-04-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE360696T1 true ATE360696T1 (de) | 2007-05-15 |
Family
ID=26910034
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01950827T ATE360696T1 (de) | 2000-06-30 | 2001-06-29 | Interferon-ähnliches protein zcyto21 |
AT06012489T ATE404670T1 (de) | 2000-06-30 | 2001-06-29 | Allelische variante des interferon-ähnlichen proteins zcyto21 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06012489T ATE404670T1 (de) | 2000-06-30 | 2001-06-29 | Allelische variante des interferon-ähnlichen proteins zcyto21 |
Country Status (13)
Country | Link |
---|---|
US (18) | US6927040B2 (de) |
EP (4) | EP1939293A3 (de) |
JP (1) | JP4377126B2 (de) |
CN (1) | CN100448993C (de) |
AT (2) | ATE360696T1 (de) |
AU (1) | AU2001271786A1 (de) |
BR (1) | BR0112119A (de) |
CA (1) | CA2413258C (de) |
DE (2) | DE60135393D1 (de) |
DK (2) | DK1294888T3 (de) |
ES (2) | ES2286128T3 (de) |
RU (1) | RU2292394C2 (de) |
WO (1) | WO2002002627A2 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1939293A3 (de) * | 2000-06-30 | 2008-07-09 | ZymoGenetics, Inc. | Interferonähnliches Protein ZCYTO21 |
US7038032B2 (en) * | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
US7910313B2 (en) * | 2001-04-20 | 2011-03-22 | Zymogenetics, Inc. | Cytokine protein family |
EP1412499A4 (de) * | 2001-05-10 | 2005-04-06 | Immunex Corp | Zytokinpolypeptide |
AU2002357643A1 (en) * | 2001-08-29 | 2003-04-14 | Vanderbilt University | The human mob-5 (il-24) receptors and uses thereof |
WO2003066002A2 (en) * | 2002-02-08 | 2003-08-14 | University Of Medicine And Dentistry Of New Jersey | IFN-a/b-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION |
WO2003089603A2 (en) | 2002-04-19 | 2003-10-30 | Zymogenetics, Inc. | Cytokine receptor |
CA2496002A1 (en) * | 2002-08-07 | 2004-02-19 | Delta Biotechnology Ltd. | Albumin-fused ciliary neurotrophic factor |
US7135170B2 (en) * | 2002-10-23 | 2006-11-14 | Zymogenetics, Inc. | Methods for treating viral infection using IL-28 and IL-29 |
ES2303132T3 (es) | 2003-08-07 | 2008-08-01 | Zymogenetics, Inc. | Preparaciones homogeneas de il-29. |
CA2558829C (en) * | 2004-04-02 | 2014-03-11 | Zymogenetics, Inc. | Methods for treating viral infection using il-28 and il-29 cysteine mutants |
WO2006012644A2 (en) * | 2004-07-29 | 2006-02-02 | Zymogenetics, Inc. | Use of il-28 and il-29 to treat cancer |
US20060178301A1 (en) * | 2005-02-04 | 2006-08-10 | Mathias Jurs | Albumin-fused ciliary neurotrophic factor |
WO2007013944A2 (en) * | 2005-07-20 | 2007-02-01 | Zymogenetics, Inc. | Use of truncated cysteine il28 and il29 mutants to treat cancers and autoimmune disorders |
EP1912668A2 (de) * | 2005-07-20 | 2008-04-23 | ZymoGenetics, Inc. | Il28- und il29-verkürzte cystein-mutanten und diese verwendende antivirale verfahren |
PL1931704T3 (pl) | 2005-10-04 | 2011-06-30 | Zymogenetics L L C | Wytwarzanie i oczyszczanie IL-29 |
TW200744634A (en) * | 2006-02-21 | 2007-12-16 | Wyeth Corp | Methods of using antibodies against human IL-22 |
US7883700B2 (en) | 2007-12-07 | 2011-02-08 | Zymogenetics, Inc. | Anti-human IL-21 monoclonal antibodies |
AU2009231598B2 (en) | 2008-04-04 | 2015-03-12 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using IL-28 and compositions and methods of using the same |
CN103536906A (zh) * | 2008-06-05 | 2014-01-29 | 津莫吉尼蒂克斯公司 | 利用聚乙二醇化的iii 型干扰素治疗丙型肝炎 |
WO2010045261A1 (en) * | 2008-10-13 | 2010-04-22 | Zymogenetics, Llc | Single chain fc type iii interferons and methods of using same |
CN102858691B (zh) | 2010-04-28 | 2015-09-23 | 株式会社村田制作所 | 具有阴离子控制的介电性质的钙钛矿材料、薄膜电容器器件及其制造方法 |
FR2975185A1 (fr) * | 2011-05-12 | 2012-11-16 | Univ Claude Bernard Lyon | Procede de determination in vitro de la presence d'une sclerose en plaques |
RU2549710C2 (ru) * | 2012-06-29 | 2015-04-27 | Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) | Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа |
CN102998450B (zh) * | 2012-11-22 | 2014-10-15 | 北京正旦国际科技有限责任公司 | 一种食管癌免疫质谱检测试剂盒的制备方法 |
JP6730926B2 (ja) | 2014-01-08 | 2020-07-29 | プロージット ソウル バイオテクノロジー (ベイジン) カンパニー リミテッド | 融合ポリペプチドおよび使用方法 |
US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
KR102514971B1 (ko) | 2015-04-21 | 2023-03-27 | 아이거 바이오파마슈티컬스 인코포레이티드 | 로나파르닙 및 리토나버를 포함하는 약제 조성물 |
WO2017143253A1 (en) | 2016-02-19 | 2017-08-24 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection with interferon lambda |
EP3518958A4 (de) * | 2016-09-30 | 2021-03-31 | The Board of Trustees of the Leland Stanford Junior University | Variante typ-iii-interferone und synthekine |
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DE3000213A1 (de) | 1980-01-04 | 1981-07-09 | Zahnfabrik Wienand Söhne & Co GmbH, 6072 Dreieich | Verfahren zur herstellung eines vernetzten polymerisatz fuer dentalzwecke |
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EP1939293A3 (de) * | 2000-06-30 | 2008-07-09 | ZymoGenetics, Inc. | Interferonähnliches Protein ZCYTO21 |
AU2002255478A1 (en) * | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
US7038032B2 (en) | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
EP1412499A4 (de) | 2001-05-10 | 2005-04-06 | Immunex Corp | Zytokinpolypeptide |
JP3939160B2 (ja) * | 2001-05-25 | 2007-07-04 | 独立行政法人科学技術振興機構 | 腎臓における外来遺伝子発現方法 |
WO2003066002A2 (en) | 2002-02-08 | 2003-08-14 | University Of Medicine And Dentistry Of New Jersey | IFN-a/b-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION |
US7135170B2 (en) | 2002-10-23 | 2006-11-14 | Zymogenetics, Inc. | Methods for treating viral infection using IL-28 and IL-29 |
ES2303132T3 (es) | 2003-08-07 | 2008-08-01 | Zymogenetics, Inc. | Preparaciones homogeneas de il-29. |
CA2558829C (en) | 2004-04-02 | 2014-03-11 | Zymogenetics, Inc. | Methods for treating viral infection using il-28 and il-29 cysteine mutants |
WO2007013944A2 (en) * | 2005-07-20 | 2007-02-01 | Zymogenetics, Inc. | Use of truncated cysteine il28 and il29 mutants to treat cancers and autoimmune disorders |
CN103536906A (zh) | 2008-06-05 | 2014-01-29 | 津莫吉尼蒂克斯公司 | 利用聚乙二醇化的iii 型干扰素治疗丙型肝炎 |
WO2010045261A1 (en) | 2008-10-13 | 2010-04-22 | Zymogenetics, Llc | Single chain fc type iii interferons and methods of using same |
-
2001
- 2001-06-29 EP EP08100616A patent/EP1939293A3/de not_active Withdrawn
- 2001-06-29 ES ES01950827T patent/ES2286128T3/es not_active Expired - Lifetime
- 2001-06-29 CA CA2413258A patent/CA2413258C/en not_active Expired - Lifetime
- 2001-06-29 RU RU2003103099/13A patent/RU2292394C2/ru active
- 2001-06-29 EP EP01950827A patent/EP1294888B1/de not_active Expired - Lifetime
- 2001-06-29 EP EP06012489A patent/EP1717316B1/de not_active Expired - Lifetime
- 2001-06-29 DE DE60135393T patent/DE60135393D1/de not_active Expired - Lifetime
- 2001-06-29 ES ES06012489T patent/ES2311253T3/es not_active Expired - Lifetime
- 2001-06-29 DK DK01950827T patent/DK1294888T3/da active
- 2001-06-29 JP JP2002507878A patent/JP4377126B2/ja not_active Expired - Lifetime
- 2001-06-29 EP EP09172071A patent/EP2132984A3/de not_active Withdrawn
- 2001-06-29 CN CNB018131530A patent/CN100448993C/zh not_active Ceased
- 2001-06-29 DK DK06012489T patent/DK1717316T3/da active
- 2001-06-29 AT AT01950827T patent/ATE360696T1/de active
- 2001-06-29 WO PCT/US2001/021087 patent/WO2002002627A2/en active IP Right Grant
- 2001-06-29 AT AT06012489T patent/ATE404670T1/de active
- 2001-06-29 US US09/895,834 patent/US6927040B2/en not_active Expired - Lifetime
- 2001-06-29 AU AU2001271786A patent/AU2001271786A1/en not_active Abandoned
- 2001-06-29 BR BR0112119-7A patent/BR0112119A/pt active Search and Examination
- 2001-06-29 DE DE60128093T patent/DE60128093T2/de not_active Expired - Lifetime
-
2004
- 2004-03-02 US US10/790,996 patent/US20040146988A1/en not_active Abandoned
- 2004-08-27 US US10/927,891 patent/US7252969B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/927,815 patent/US7253261B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/928,539 patent/US7241870B2/en not_active Expired - Lifetime
-
2006
- 2006-10-10 US US11/548,023 patent/US7445913B2/en not_active Expired - Lifetime
- 2006-10-10 US US11/548,056 patent/US7485700B2/en not_active Expired - Lifetime
- 2006-10-10 US US11/548,138 patent/US20070049736A1/en not_active Abandoned
- 2006-10-10 US US11/548,108 patent/US20070043209A1/en not_active Abandoned
-
2007
- 2007-10-16 US US11/873,272 patent/US7655223B2/en not_active Expired - Lifetime
- 2007-10-26 US US11/925,097 patent/US7498154B2/en not_active Expired - Lifetime
-
2008
- 2008-01-09 US US11/971,624 patent/US20080214788A1/en not_active Abandoned
- 2008-12-22 US US12/341,273 patent/US20090326204A1/en not_active Abandoned
-
2009
- 2009-11-30 US US12/628,078 patent/US7833520B2/en not_active Expired - Fee Related
-
2010
- 2010-09-30 US US12/895,139 patent/US7919595B2/en not_active Expired - Fee Related
-
2011
- 2011-03-02 US US13/039,223 patent/US20110172170A1/en not_active Abandoned
- 2011-09-08 US US13/227,548 patent/US20120036590A1/en not_active Abandoned
-
2012
- 2012-05-03 US US13/463,046 patent/US20120258458A1/en not_active Abandoned
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