ATE360696T1 - Interferon-ähnliches protein zcyto21 - Google Patents
Interferon-ähnliches protein zcyto21Info
- Publication number
- ATE360696T1 ATE360696T1 AT01950827T AT01950827T ATE360696T1 AT E360696 T1 ATE360696 T1 AT E360696T1 AT 01950827 T AT01950827 T AT 01950827T AT 01950827 T AT01950827 T AT 01950827T AT E360696 T1 ATE360696 T1 AT E360696T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- zcyto21
- interferon
- acid sequence
- genetically engineered
- Prior art date
Links
- 101100232735 Homo sapiens IFNL1 gene Proteins 0.000 title 1
- 102100020990 Interferon lambda-1 Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 238000011813 knockout mouse model Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000011830 transgenic mouse model Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21544600P | 2000-06-30 | 2000-06-30 | |
| US28542401P | 2001-04-20 | 2001-04-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE360696T1 true ATE360696T1 (de) | 2007-05-15 |
Family
ID=26910034
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01950827T ATE360696T1 (de) | 2000-06-30 | 2001-06-29 | Interferon-ähnliches protein zcyto21 |
| AT06012489T ATE404670T1 (de) | 2000-06-30 | 2001-06-29 | Allelische variante des interferon-ähnlichen proteins zcyto21 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06012489T ATE404670T1 (de) | 2000-06-30 | 2001-06-29 | Allelische variante des interferon-ähnlichen proteins zcyto21 |
Country Status (13)
| Country | Link |
|---|---|
| US (18) | US6927040B2 (de) |
| EP (4) | EP1294888B1 (de) |
| JP (1) | JP4377126B2 (de) |
| CN (1) | CN100448993C (de) |
| AT (2) | ATE360696T1 (de) |
| AU (1) | AU2001271786A1 (de) |
| BR (1) | BR0112119A (de) |
| CA (1) | CA2413258C (de) |
| DE (2) | DE60135393D1 (de) |
| DK (2) | DK1717316T3 (de) |
| ES (2) | ES2311253T3 (de) |
| RU (1) | RU2292394C2 (de) |
| WO (1) | WO2002002627A2 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1717316T3 (da) * | 2000-06-30 | 2008-12-08 | Zymogenetics Inc | Allelisk variant af interferon-lignende protein Zcyto21 |
| US7038032B2 (en) * | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
| US7910313B2 (en) | 2001-04-20 | 2011-03-22 | Zymogenetics, Inc. | Cytokine protein family |
| WO2002092762A2 (en) * | 2001-05-10 | 2002-11-21 | Immunex Corporation | Cytokine polypeptides |
| US6902930B2 (en) * | 2001-08-29 | 2005-06-07 | Vanderbilt University | Human Mob-5 (IL-24) receptors and uses thereof |
| AU2003215136A1 (en) | 2002-02-08 | 2003-09-02 | University Of Medicine And Dentistry Of New Jersey | Ifn-a/b-independent mechanism of antiviral protection |
| EP1497415B1 (de) | 2002-04-19 | 2010-12-29 | ZymoGenetics, L.L.C. | Verfahren zum nachweis oder zur modulierung der wechselwirkung eines cytokinrezeptors mit seinem ligand |
| CA2496002A1 (en) * | 2002-08-07 | 2004-02-19 | Delta Biotechnology Ltd. | Albumin-fused ciliary neurotrophic factor |
| EP1575609A4 (de) * | 2002-10-23 | 2010-12-15 | Zymogenetics L L C | Verfahren zur behandlung von virusinfektionen unter verwendung von il-28 und il-29 |
| ES2303132T3 (es) * | 2003-08-07 | 2008-08-01 | Zymogenetics, Inc. | Preparaciones homogeneas de il-29. |
| CA2558829C (en) * | 2004-04-02 | 2014-03-11 | Zymogenetics, Inc. | Methods for treating viral infection using il-28 and il-29 cysteine mutants |
| CN101829318B (zh) * | 2004-07-29 | 2012-07-04 | 津莫吉尼蒂克斯有限责任公司 | Il-28和il-29治疗癌症和自身免疫性疾病的用途 |
| RU2389502C2 (ru) * | 2004-07-29 | 2010-05-20 | Займодженетикс, Инк. | Применение il-28 и il-29 для лечения карциномы и аутоиммунных нарушений |
| US20060178301A1 (en) * | 2005-02-04 | 2006-08-10 | Mathias Jurs | Albumin-fused ciliary neurotrophic factor |
| CA2616122A1 (en) * | 2005-07-20 | 2007-01-25 | Zymogenetics, Inc. | Il28 and il29 truncated cysteine mutants and antiviral methods of using same |
| JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
| ES2357152T3 (es) | 2005-10-04 | 2011-04-19 | Zymogenetics, L.L.C. | Producción y purificación de il-29. |
| TW200744634A (en) * | 2006-02-21 | 2007-12-16 | Wyeth Corp | Methods of using antibodies against human IL-22 |
| EP3103813A1 (de) | 2007-12-07 | 2016-12-14 | ZymoGenetics, Inc. | Anti-humane il-21 monoklonale antikörper |
| CN105535961A (zh) | 2008-04-04 | 2016-05-04 | 宾夕法尼亚大学托管会 | 使用il-28和组合物的疫苗和免疫治疗及其使用方法 |
| CN102099051A (zh) * | 2008-06-05 | 2011-06-15 | 津莫吉尼蒂克斯公司 | 利用聚乙二醇化的iii型干扰素治疗丙型肝炎 |
| EP2344546A1 (de) * | 2008-10-13 | 2011-07-20 | Zymogenetics, Inc. | Einzelketten-fc-typ-iii-interferone und verfahren zuen zu deren anwendung |
| WO2011135439A1 (en) | 2010-04-28 | 2011-11-03 | Murata Manufacturing Co., Ltd. | Perovskite material with anion-controlled dielectric properties, thin film capacitor device, and method for manufacturing the same |
| FR2975185A1 (fr) * | 2011-05-12 | 2012-11-16 | Univ Claude Bernard Lyon | Procede de determination in vitro de la presence d'une sclerose en plaques |
| RU2549710C2 (ru) * | 2012-06-29 | 2015-04-27 | Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) | Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа |
| CN102998450B (zh) * | 2012-11-22 | 2014-10-15 | 北京正旦国际科技有限责任公司 | 一种食管癌免疫质谱检测试剂盒的制备方法 |
| EP3092248B1 (de) | 2014-01-08 | 2021-06-23 | Prosit Sole Biotechnology (Beijing) Co. Ltd | Fusionspolypeptide und verfahren zur verwendung |
| US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
| JP2018517673A (ja) | 2015-04-21 | 2018-07-05 | アイガー・バイオファーマシューティカルズ・インコーポレイテッドEiger Biopharmaceuticals, Inc. | ロナファルニブおよびリトナビルを含む医薬組成物 |
| JP7674628B2 (ja) | 2016-02-19 | 2025-05-12 | イーアイティー・ファーマ・インコーポレイテッド | インターフェロンラムダによるデルタ型肝炎ウイルス感染の処置 |
| US11198717B2 (en) * | 2016-09-30 | 2021-12-14 | The Board Of Trustees Of The Leland Stanford Junior University | Variant type III interferons and synthekines |
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| DE3000213A1 (de) | 1980-01-04 | 1981-07-09 | Zahnfabrik Wienand Söhne & Co GmbH, 6072 Dreieich | Verfahren zur herstellung eines vernetzten polymerisatz fuer dentalzwecke |
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| DK1717316T3 (da) | 2000-06-30 | 2008-12-08 | Zymogenetics Inc | Allelisk variant af interferon-lignende protein Zcyto21 |
| AU2002255478A1 (en) * | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| US7038032B2 (en) | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
| WO2002092762A2 (en) | 2001-05-10 | 2002-11-21 | Immunex Corporation | Cytokine polypeptides |
| JP3939160B2 (ja) * | 2001-05-25 | 2007-07-04 | 独立行政法人科学技術振興機構 | 腎臓における外来遺伝子発現方法 |
| AU2003215136A1 (en) | 2002-02-08 | 2003-09-02 | University Of Medicine And Dentistry Of New Jersey | Ifn-a/b-independent mechanism of antiviral protection |
| EP1575609A4 (de) | 2002-10-23 | 2010-12-15 | Zymogenetics L L C | Verfahren zur behandlung von virusinfektionen unter verwendung von il-28 und il-29 |
| ES2303132T3 (es) | 2003-08-07 | 2008-08-01 | Zymogenetics, Inc. | Preparaciones homogeneas de il-29. |
| CA2558829C (en) | 2004-04-02 | 2014-03-11 | Zymogenetics, Inc. | Methods for treating viral infection using il-28 and il-29 cysteine mutants |
| JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
| CN102099051A (zh) | 2008-06-05 | 2011-06-15 | 津莫吉尼蒂克斯公司 | 利用聚乙二醇化的iii型干扰素治疗丙型肝炎 |
| EP2344546A1 (de) | 2008-10-13 | 2011-07-20 | Zymogenetics, Inc. | Einzelketten-fc-typ-iii-interferone und verfahren zuen zu deren anwendung |
-
2001
- 2001-06-29 DK DK06012489T patent/DK1717316T3/da active
- 2001-06-29 CN CNB018131530A patent/CN100448993C/zh not_active Ceased
- 2001-06-29 BR BR0112119-7A patent/BR0112119A/pt active Search and Examination
- 2001-06-29 DE DE60135393T patent/DE60135393D1/de not_active Expired - Lifetime
- 2001-06-29 JP JP2002507878A patent/JP4377126B2/ja not_active Expired - Lifetime
- 2001-06-29 DK DK01950827T patent/DK1294888T3/da active
- 2001-06-29 AU AU2001271786A patent/AU2001271786A1/en not_active Abandoned
- 2001-06-29 EP EP01950827A patent/EP1294888B1/de not_active Expired - Lifetime
- 2001-06-29 DE DE60128093T patent/DE60128093T2/de not_active Expired - Lifetime
- 2001-06-29 ES ES06012489T patent/ES2311253T3/es not_active Expired - Lifetime
- 2001-06-29 EP EP06012489A patent/EP1717316B1/de not_active Expired - Lifetime
- 2001-06-29 AT AT01950827T patent/ATE360696T1/de active
- 2001-06-29 CA CA2413258A patent/CA2413258C/en not_active Expired - Lifetime
- 2001-06-29 ES ES01950827T patent/ES2286128T3/es not_active Expired - Lifetime
- 2001-06-29 US US09/895,834 patent/US6927040B2/en not_active Expired - Lifetime
- 2001-06-29 AT AT06012489T patent/ATE404670T1/de active
- 2001-06-29 RU RU2003103099/13A patent/RU2292394C2/ru active
- 2001-06-29 WO PCT/US2001/021087 patent/WO2002002627A2/en not_active Ceased
- 2001-06-29 EP EP08100616A patent/EP1939293A3/de not_active Withdrawn
- 2001-06-29 EP EP09172071A patent/EP2132984A3/de not_active Withdrawn
-
2004
- 2004-03-02 US US10/790,996 patent/US20040146988A1/en not_active Abandoned
- 2004-08-27 US US10/928,539 patent/US7241870B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/927,815 patent/US7253261B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/927,891 patent/US7252969B2/en not_active Expired - Lifetime
-
2006
- 2006-10-10 US US11/548,108 patent/US20070043209A1/en not_active Abandoned
- 2006-10-10 US US11/548,056 patent/US7485700B2/en not_active Expired - Lifetime
- 2006-10-10 US US11/548,023 patent/US7445913B2/en not_active Expired - Lifetime
- 2006-10-10 US US11/548,138 patent/US20070049736A1/en not_active Abandoned
-
2007
- 2007-10-16 US US11/873,272 patent/US7655223B2/en not_active Expired - Lifetime
- 2007-10-26 US US11/925,097 patent/US7498154B2/en not_active Expired - Lifetime
-
2008
- 2008-01-09 US US11/971,624 patent/US20080214788A1/en not_active Abandoned
- 2008-12-22 US US12/341,273 patent/US20090326204A1/en not_active Abandoned
-
2009
- 2009-11-30 US US12/628,078 patent/US7833520B2/en not_active Expired - Fee Related
-
2010
- 2010-09-30 US US12/895,139 patent/US7919595B2/en not_active Expired - Fee Related
-
2011
- 2011-03-02 US US13/039,223 patent/US20110172170A1/en not_active Abandoned
- 2011-09-08 US US13/227,548 patent/US20120036590A1/en not_active Abandoned
-
2012
- 2012-05-03 US US13/463,046 patent/US20120258458A1/en not_active Abandoned
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