ATE404670T1 - Allelische variante des interferon-ähnlichen proteins zcyto21 - Google Patents
Allelische variante des interferon-ähnlichen proteins zcyto21Info
- Publication number
- ATE404670T1 ATE404670T1 AT06012489T AT06012489T ATE404670T1 AT E404670 T1 ATE404670 T1 AT E404670T1 AT 06012489 T AT06012489 T AT 06012489T AT 06012489 T AT06012489 T AT 06012489T AT E404670 T1 ATE404670 T1 AT E404670T1
- Authority
- AT
- Austria
- Prior art keywords
- interferon
- zcyto21
- allelic variant
- amino acid
- protein
- Prior art date
Links
- 101100232735 Homo sapiens IFNL1 gene Proteins 0.000 title 1
- 102100020990 Interferon lambda-1 Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 238000011813 knockout mouse model Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 238000011830 transgenic mouse model Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21544600P | 2000-06-30 | 2000-06-30 | |
US28542401P | 2001-04-20 | 2001-04-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE404670T1 true ATE404670T1 (de) | 2008-08-15 |
Family
ID=26910034
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06012489T ATE404670T1 (de) | 2000-06-30 | 2001-06-29 | Allelische variante des interferon-ähnlichen proteins zcyto21 |
AT01950827T ATE360696T1 (de) | 2000-06-30 | 2001-06-29 | Interferon-ähnliches protein zcyto21 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01950827T ATE360696T1 (de) | 2000-06-30 | 2001-06-29 | Interferon-ähnliches protein zcyto21 |
Country Status (13)
Country | Link |
---|---|
US (18) | US6927040B2 (de) |
EP (4) | EP1294888B1 (de) |
JP (1) | JP4377126B2 (de) |
CN (1) | CN100448993C (de) |
AT (2) | ATE404670T1 (de) |
AU (1) | AU2001271786A1 (de) |
BR (1) | BR0112119A (de) |
CA (1) | CA2413258C (de) |
DE (2) | DE60128093T2 (de) |
DK (2) | DK1717316T3 (de) |
ES (2) | ES2311253T3 (de) |
RU (1) | RU2292394C2 (de) |
WO (1) | WO2002002627A2 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1294888B1 (de) * | 2000-06-30 | 2007-04-25 | ZymoGenetics, Inc. | Interferon-ähnliches protein zcyto21 |
US7038032B2 (en) * | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
US7910313B2 (en) * | 2001-04-20 | 2011-03-22 | Zymogenetics, Inc. | Cytokine protein family |
MXPA03010181A (es) * | 2001-05-10 | 2004-03-16 | Immunex Corp | Polipeptidos de citocinas. |
US6902930B2 (en) * | 2001-08-29 | 2005-06-07 | Vanderbilt University | Human Mob-5 (IL-24) receptors and uses thereof |
WO2003066002A2 (en) * | 2002-02-08 | 2003-08-14 | University Of Medicine And Dentistry Of New Jersey | IFN-a/b-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION |
CN101676728A (zh) | 2002-04-19 | 2010-03-24 | 津莫吉尼蒂克斯公司 | 细胞因子受体 |
AU2003271043A1 (en) * | 2002-08-07 | 2004-02-25 | Novozymes Biopharma Dk A/S | Albumin-fused ciliary neurotrophic factor |
EP1575609A4 (de) * | 2002-10-23 | 2010-12-15 | Zymogenetics L L C | Verfahren zur behandlung von virusinfektionen unter verwendung von il-28 und il-29 |
EP1927600A1 (de) | 2003-08-07 | 2008-06-04 | Zymogenetics, Inc. | Homogene Präparate von IL-28 und IL-29 |
EP1750749A2 (de) * | 2004-04-02 | 2007-02-14 | ZymoGenetics, Inc. | Il-28 und il-29-cystein-mutanten zur behandlung von virusinfektion |
CA2574564C (en) * | 2004-07-29 | 2013-04-16 | Zymogenetics, Inc. | Use of il-28 and il-29 to treat cancer and autoimmune disorders |
US20060178301A1 (en) * | 2005-02-04 | 2006-08-10 | Mathias Jurs | Albumin-fused ciliary neurotrophic factor |
US20070053933A1 (en) * | 2005-07-20 | 2007-03-08 | Sheppard Paul O | IL28 and IL29 TRUNCATED CYSTEINE MUTANTS AND ANTIVIRAL METHODS OF USING SAME |
JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
ES2357152T3 (es) * | 2005-10-04 | 2011-04-19 | Zymogenetics, L.L.C. | Producción y purificación de il-29. |
TW200744634A (en) * | 2006-02-21 | 2007-12-16 | Wyeth Corp | Methods of using antibodies against human IL-22 |
ES2572231T3 (es) | 2007-12-07 | 2016-05-30 | Zymogenetics Inc | Anticuerpos monoclonales anti-IL-21 humana |
WO2009124309A2 (en) * | 2008-04-04 | 2009-10-08 | The Trustees Of The University Of Pennsylvania | Vaccines and immunotherapeutics using il-28 and compositions and methods of using the same |
WO2009149377A1 (en) * | 2008-06-05 | 2009-12-10 | Zymogenetics, Llc | Use of pegylated type iii interferons for the treatment of hepatitis c |
US20110263484A1 (en) * | 2008-10-13 | 2011-10-27 | Zymogenetics, Inc. | Single chain fc type iii interferons and methods of using same |
JP5673796B2 (ja) | 2010-04-28 | 2015-02-18 | 株式会社村田製作所 | アニオン制御された誘電特性を有するペロブスカイト材料の製造方法、およびそれを用いた薄膜コンデンサ装置の製造方法 |
FR2975185A1 (fr) * | 2011-05-12 | 2012-11-16 | Univ Claude Bernard Lyon | Procede de determination in vitro de la presence d'une sclerose en plaques |
RU2549710C2 (ru) * | 2012-06-29 | 2015-04-27 | Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) | Способ очистки рекомбинантного белка интерфероноподобного фактора iii типа |
CN102998450B (zh) * | 2012-11-22 | 2014-10-15 | 北京正旦国际科技有限责任公司 | 一种食管癌免疫质谱检测试剂盒的制备方法 |
WO2015103749A1 (en) | 2014-01-08 | 2015-07-16 | Prosit Sole Biotechnology (Beijing) Co. Ltd | Fusion polypeptides and methods of use |
US10076512B2 (en) | 2014-05-01 | 2018-09-18 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
US11311519B2 (en) | 2014-05-01 | 2022-04-26 | Eiger Biopharmaceuticals, Inc. | Treatment of hepatitis delta virus infection |
ES2844848T3 (es) | 2015-04-21 | 2021-07-22 | Eiger Biopharmaceuticals Inc | Composiciones farmacéuticas que comprenden Lonafarnib y Ritonavir |
RS61944B1 (sr) | 2016-02-19 | 2021-07-30 | Eiger Biopharmaceuticals Inc | Lečenje infekcije hepatitis delta virusom sa interferonom lambda |
CA3038533A1 (en) * | 2016-09-30 | 2018-04-05 | The Board Of Trustees Of The Leland Stanford Junior University | Variant type iii interferons and synthekines |
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AR021876A1 (es) * | 1998-12-18 | 2002-08-07 | Schering Corp | Terapia de combinacion para vhc por induccion de ribavirina - interferon alfa pegilado |
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EP1294888B1 (de) * | 2000-06-30 | 2007-04-25 | ZymoGenetics, Inc. | Interferon-ähnliches protein zcyto21 |
AU2002255478A1 (en) * | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
US7038032B2 (en) | 2001-04-20 | 2006-05-02 | Zymogenetics, Inc. | Cytokine protein family |
MXPA03010181A (es) | 2001-05-10 | 2004-03-16 | Immunex Corp | Polipeptidos de citocinas. |
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WO2003066002A2 (en) | 2002-02-08 | 2003-08-14 | University Of Medicine And Dentistry Of New Jersey | IFN-a/b-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION |
EP1575609A4 (de) | 2002-10-23 | 2010-12-15 | Zymogenetics L L C | Verfahren zur behandlung von virusinfektionen unter verwendung von il-28 und il-29 |
EP1927600A1 (de) | 2003-08-07 | 2008-06-04 | Zymogenetics, Inc. | Homogene Präparate von IL-28 und IL-29 |
EP1750749A2 (de) | 2004-04-02 | 2007-02-14 | ZymoGenetics, Inc. | Il-28 und il-29-cystein-mutanten zur behandlung von virusinfektion |
JP4987001B2 (ja) * | 2005-07-20 | 2012-07-25 | ザイモジェネティクス リミテッド ライアビリティ カンパニー | 癌および自己免疫障害を処置するためのil28およびil29の短縮型システイン変異体の使用法 |
WO2009149377A1 (en) | 2008-06-05 | 2009-12-10 | Zymogenetics, Llc | Use of pegylated type iii interferons for the treatment of hepatitis c |
US20110263484A1 (en) | 2008-10-13 | 2011-10-27 | Zymogenetics, Inc. | Single chain fc type iii interferons and methods of using same |
-
2001
- 2001-06-29 EP EP01950827A patent/EP1294888B1/de not_active Expired - Lifetime
- 2001-06-29 JP JP2002507878A patent/JP4377126B2/ja not_active Expired - Lifetime
- 2001-06-29 US US09/895,834 patent/US6927040B2/en not_active Expired - Lifetime
- 2001-06-29 EP EP09172071A patent/EP2132984A3/de not_active Withdrawn
- 2001-06-29 CN CNB018131530A patent/CN100448993C/zh not_active Ceased
- 2001-06-29 DE DE60128093T patent/DE60128093T2/de not_active Expired - Lifetime
- 2001-06-29 DK DK06012489T patent/DK1717316T3/da active
- 2001-06-29 AT AT06012489T patent/ATE404670T1/de active
- 2001-06-29 BR BR0112119-7A patent/BR0112119A/pt active Search and Examination
- 2001-06-29 CA CA2413258A patent/CA2413258C/en not_active Expired - Lifetime
- 2001-06-29 DK DK01950827T patent/DK1294888T3/da active
- 2001-06-29 RU RU2003103099/13A patent/RU2292394C2/ru active
- 2001-06-29 DE DE60135393T patent/DE60135393D1/de not_active Expired - Lifetime
- 2001-06-29 AU AU2001271786A patent/AU2001271786A1/en not_active Abandoned
- 2001-06-29 ES ES06012489T patent/ES2311253T3/es not_active Expired - Lifetime
- 2001-06-29 EP EP06012489A patent/EP1717316B1/de not_active Expired - Lifetime
- 2001-06-29 WO PCT/US2001/021087 patent/WO2002002627A2/en active IP Right Grant
- 2001-06-29 EP EP08100616A patent/EP1939293A3/de not_active Withdrawn
- 2001-06-29 ES ES01950827T patent/ES2286128T3/es not_active Expired - Lifetime
- 2001-06-29 AT AT01950827T patent/ATE360696T1/de active
-
2004
- 2004-03-02 US US10/790,996 patent/US20040146988A1/en not_active Abandoned
- 2004-08-27 US US10/927,891 patent/US7252969B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/927,815 patent/US7253261B2/en not_active Expired - Lifetime
- 2004-08-27 US US10/928,539 patent/US7241870B2/en not_active Expired - Lifetime
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2006
- 2006-10-10 US US11/548,138 patent/US20070049736A1/en not_active Abandoned
- 2006-10-10 US US11/548,108 patent/US20070043209A1/en not_active Abandoned
- 2006-10-10 US US11/548,056 patent/US7485700B2/en not_active Expired - Lifetime
- 2006-10-10 US US11/548,023 patent/US7445913B2/en not_active Expired - Lifetime
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2007
- 2007-10-16 US US11/873,272 patent/US7655223B2/en not_active Expired - Lifetime
- 2007-10-26 US US11/925,097 patent/US7498154B2/en not_active Expired - Lifetime
-
2008
- 2008-01-09 US US11/971,624 patent/US20080214788A1/en not_active Abandoned
- 2008-12-22 US US12/341,273 patent/US20090326204A1/en not_active Abandoned
-
2009
- 2009-11-30 US US12/628,078 patent/US7833520B2/en not_active Expired - Fee Related
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2010
- 2010-09-30 US US12/895,139 patent/US7919595B2/en not_active Expired - Fee Related
-
2011
- 2011-03-02 US US13/039,223 patent/US20110172170A1/en not_active Abandoned
- 2011-09-08 US US13/227,548 patent/US20120036590A1/en not_active Abandoned
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2012
- 2012-05-03 US US13/463,046 patent/US20120258458A1/en not_active Abandoned
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