DK1245564T3 - Benzamidinderivater - Google Patents

Benzamidinderivater

Info

Publication number
DK1245564T3
DK1245564T3 DK00970070T DK00970070T DK1245564T3 DK 1245564 T3 DK1245564 T3 DK 1245564T3 DK 00970070 T DK00970070 T DK 00970070T DK 00970070 T DK00970070 T DK 00970070T DK 1245564 T3 DK1245564 T3 DK 1245564T3
Authority
DK
Denmark
Prior art keywords
group
optionally substituted
hydrogen atom
alkyl group
halogen atom
Prior art date
Application number
DK00970070T
Other languages
Danish (da)
English (en)
Inventor
Koichi Fujimoto
Fumitoshi Asai
Hayao Matsuhashi
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of DK1245564T3 publication Critical patent/DK1245564T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Manufacture Of Alloys Or Alloy Compounds (AREA)
DK00970070T 1999-10-28 2000-10-25 Benzamidinderivater DK1245564T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30719299 1999-10-28

Publications (1)

Publication Number Publication Date
DK1245564T3 true DK1245564T3 (da) 2006-08-14

Family

ID=17966162

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00970070T DK1245564T3 (da) 1999-10-28 2000-10-25 Benzamidinderivater

Country Status (26)

Country Link
US (3) US6555556B1 (ru)
EP (1) EP1245564B1 (ru)
KR (1) KR100642953B1 (ru)
CN (2) CN1572882A (ru)
AT (1) ATE322479T1 (ru)
AU (1) AU776193B2 (ru)
BR (1) BR0015120A (ru)
CA (1) CA2389156C (ru)
CY (1) CY1106116T1 (ru)
CZ (1) CZ20021432A3 (ru)
DE (1) DE60027204T2 (ru)
DK (1) DK1245564T3 (ru)
ES (1) ES2261248T3 (ru)
HK (1) HK1047431B (ru)
HU (1) HUP0203161A3 (ru)
IL (2) IL149306A0 (ru)
MX (1) MXPA02004218A (ru)
NO (1) NO323147B1 (ru)
NZ (1) NZ518581A (ru)
PL (1) PL354619A1 (ru)
PT (1) PT1245564E (ru)
RU (1) RU2222529C2 (ru)
TR (1) TR200201654T2 (ru)
TW (1) TWI226886B (ru)
WO (1) WO2001030756A1 (ru)
ZA (1) ZA200203278B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001030756A1 (fr) * 1999-10-28 2001-05-03 Sankyo Company, Limited Derives de benzamidine
BR0208678A (pt) 2001-04-05 2004-03-30 Sankyo Co Composto, composição farmacêutica, uso de um composto
WO2002089803A1 (en) * 2001-05-07 2002-11-14 Sankyo Company, Limited Composition for iontophoresis
KR100969847B1 (ko) 2002-03-15 2010-07-13 깃세이 야쿠힌 고교 가부시키가이샤 5-히드록시카르밤이미도일-2-히드록시벤젠술폰아미드유도체의 신규한 결정
ATE445397T1 (de) * 2004-11-23 2009-10-15 Dong Wha Pharm Co Ltd N-hydroxy-4-ä5-ä4-(5-isopropyl-2-methyl-1,3- thiazol-4-yl)phenoxyüpentoxyübenzamidin 2 methansulfonsauresalz
CN103159620A (zh) * 2013-03-28 2013-06-19 广西师范大学 一种2-羟基间苯二甲酸的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA928276B (en) 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.
US5731324A (en) * 1993-07-22 1998-03-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
IL112795A (en) * 1994-03-04 2001-01-28 Astrazeneca Ab Derivatives of peptides as antithrombotic drugs, their preparation, and pharmaceutical preparations containing them
WO1996016940A1 (fr) 1994-12-02 1996-06-06 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive d'amidinonaphtyle ou sel de celui-ci
ES2197257T3 (es) * 1996-01-02 2004-01-01 Aventis Pharmaceuticals Inc. N-[(aminoiminometil o aminometil)fenil-propilamidas sustituidas.
CZ86199A3 (cs) * 1996-09-12 1999-08-11 Schering Aktiengesellschaft Benzamidinové deriváty substituované cyklickou aminokyselinou a cyklické hydrokyselinové deriváty, farmaceutický prostředek obsahující tyto látky a jejich použití jako protisrážecích činidel
TW542822B (en) * 1997-01-17 2003-07-21 Ajinomoto Kk Benzamidine derivatives
US6399627B1 (en) 1999-02-11 2002-06-04 Cor Therapeutics, Inc. Inhibitors of factor Xa
US6350761B1 (en) * 1999-07-30 2002-02-26 Berlex Laboratories, Inc. Benzenamine derivatives as anti-coagulants
WO2001030756A1 (fr) * 1999-10-28 2001-05-03 Sankyo Company, Limited Derives de benzamidine

Also Published As

Publication number Publication date
HUP0203161A3 (en) 2003-12-29
NO20021990D0 (no) 2002-04-26
US6555556B1 (en) 2003-04-29
KR100642953B1 (ko) 2006-11-10
IL149306A (en) 2007-07-04
DE60027204T2 (de) 2006-11-23
WO2001030756A1 (fr) 2001-05-03
CY1106116T1 (el) 2011-06-08
CN1293052C (zh) 2007-01-03
ES2261248T3 (es) 2006-11-16
NO20021990L (no) 2002-06-25
IL149306A0 (en) 2002-11-10
HK1047431A1 (en) 2003-02-21
AU7957400A (en) 2001-05-08
NZ518581A (en) 2004-11-26
CZ20021432A3 (cs) 2002-10-16
EP1245564B1 (en) 2006-04-05
CN1572882A (zh) 2005-02-02
BR0015120A (pt) 2002-06-25
US20040248981A1 (en) 2004-12-09
CA2389156A1 (en) 2001-05-03
MXPA02004218A (es) 2002-10-17
EP1245564A4 (en) 2003-03-05
EP1245564A1 (en) 2002-10-02
AU776193B2 (en) 2004-09-02
ATE322479T1 (de) 2006-04-15
PT1245564E (pt) 2006-06-30
CA2389156C (en) 2009-05-12
TR200201654T2 (tr) 2002-12-23
HUP0203161A2 (hu) 2002-12-28
DE60027204D1 (en) 2006-05-18
ZA200203278B (en) 2003-08-26
HK1047431B (zh) 2006-07-14
KR20020092347A (ko) 2002-12-11
RU2222529C2 (ru) 2004-01-27
US20040010009A1 (en) 2004-01-15
PL354619A1 (en) 2004-02-09
CN1413189A (zh) 2003-04-23
NO323147B1 (no) 2007-01-08
TWI226886B (en) 2005-01-21

Similar Documents

Publication Publication Date Title
WO2002081448A1 (fr) Derive benzamidine
GB9801690D0 (en) Therapeutic agents
MA28010A1 (fr) Derives de piperazine et leur utilisation comme agents therapeutiques
EP1070714A4 (en) Amidine CONNECTIONS
WO2000071510A3 (en) INHIBITORS OF FACTOR Xa
PT863875E (pt) Novos compostos 4-(oxialcoxifenil)-3-oxi-piperidina para o tratamento de insuficiencia cardiaca e renal
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
WO2000047554A3 (en) INHIBITORS OF FACTOR Xa
NO20052182L (no) Nye forbindelser
DK0976748T3 (da) Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet
NO20060147L (no) Benzimidazolderivater, sammensetninger som inneholder slike, fremstilling derav og anvendelse derav
NO20060146L (no) Benzimidazolderivater, sammensetninger som inneholder slike, fremstilling derav og anvendelse derav
DK0976722T3 (da) Benzamidin-derivater
ATE416157T1 (de) Inhibitoren von integrin alpha-v-beta-6
DE60121461D1 (de) Kondensierte pyridoindolderivate
TW200420545A (en) 1-(4-benzyl-piperazin-1-yl)-3-phenyl-propenone derivatives
TR200001452T2 (tr) Bifenilamidin türevleri.
NO20022123L (no) Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII
DK1245564T3 (da) Benzamidinderivater
DK0896822T3 (da) 4-aminopyrrol (3,2-d) pyrimidiner som neuropeptide Y receptorantagonister
ATE293961T1 (de) Verwendung von hydantoin und seinen derivaten gegen hypalbuminämie
HRP20010885B1 (en) Ethanesulfonyl-piperidine derivatives
EP1130018A4 (en) DRUGS FOR DRUG ADDICTION
AU1651201A (en) Amidinophenylpyruvic acid derivative
NO893039L (no) Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler.