DK1230209T3 - Stabile salte af hidtil ukendte derivater af 3,3-diphenylpropylaminer - Google Patents
Stabile salte af hidtil ukendte derivater af 3,3-diphenylpropylaminerInfo
- Publication number
- DK1230209T3 DK1230209T3 DK00989857T DK00989857T DK1230209T3 DK 1230209 T3 DK1230209 T3 DK 1230209T3 DK 00989857 T DK00989857 T DK 00989857T DK 00989857 T DK00989857 T DK 00989857T DK 1230209 T3 DK1230209 T3 DK 1230209T3
- Authority
- DK
- Denmark
- Prior art keywords
- new
- diphenylpropylamines
- novel derivatives
- stable salts
- salts
- Prior art date
Links
- KISZTEOELCMZPY-UHFFFAOYSA-N 3,3-diphenylpropylamine Chemical class C=1C=CC=CC=1C(CCN)C1=CC=CC=C1 KISZTEOELCMZPY-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title 1
- -1 Diphenylpropylamine derivative salts Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229940051806 diphenylpropylamine derivative analgesics Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
- Luminescent Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19955190A DE19955190A1 (de) | 1999-11-16 | 1999-11-16 | Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen |
| PCT/EP2000/011309 WO2001035957A1 (de) | 1999-11-16 | 2000-11-15 | Stabile salze neuartiger derivate von 3,3-diphenylpropylaminen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1230209T3 true DK1230209T3 (da) | 2005-05-30 |
Family
ID=7929277
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06011207T DK1690536T3 (da) | 1999-11-16 | 2000-11-15 | Anvendelse af R-( )-2-(3-diisopropylamino-1-phenylpropyl)4-4-hydroxy-methyl-phenylsobutyrat hydrogenfumarat til behandling af urininkontinens og andre spasmogene lidelser |
| DK04018487T DK1481964T3 (da) | 1999-11-16 | 2000-11-15 | Stabile salte af hidtil ukendte derivater af 3,3-diphenylpropylaminer |
| DK00989857T DK1230209T3 (da) | 1999-11-16 | 2000-11-15 | Stabile salte af hidtil ukendte derivater af 3,3-diphenylpropylaminer |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06011207T DK1690536T3 (da) | 1999-11-16 | 2000-11-15 | Anvendelse af R-( )-2-(3-diisopropylamino-1-phenylpropyl)4-4-hydroxy-methyl-phenylsobutyrat hydrogenfumarat til behandling af urininkontinens og andre spasmogene lidelser |
| DK04018487T DK1481964T3 (da) | 1999-11-16 | 2000-11-15 | Stabile salte af hidtil ukendte derivater af 3,3-diphenylpropylaminer |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6858650B1 (OSRAM) |
| EP (3) | EP1230209B3 (OSRAM) |
| JP (6) | JP4083431B2 (OSRAM) |
| KR (2) | KR100563149B1 (OSRAM) |
| CN (1) | CN1215045C (OSRAM) |
| AT (3) | ATE395056T1 (OSRAM) |
| AU (1) | AU778132B2 (OSRAM) |
| BR (1) | BRPI0015610C1 (OSRAM) |
| CA (1) | CA2389749C (OSRAM) |
| CY (2) | CY1106204T1 (OSRAM) |
| CZ (2) | CZ302497B6 (OSRAM) |
| DE (5) | DE29923134U1 (OSRAM) |
| DK (3) | DK1690536T3 (OSRAM) |
| EA (1) | EA005588B1 (OSRAM) |
| ES (3) | ES2270240T3 (OSRAM) |
| GE (1) | GEP20084430B (OSRAM) |
| HK (1) | HK1045148B (OSRAM) |
| HU (2) | HU227608B1 (OSRAM) |
| IL (2) | IL149567A0 (OSRAM) |
| IS (2) | IS2124B (OSRAM) |
| MX (1) | MXPA02004603A (OSRAM) |
| NO (2) | NO323920B1 (OSRAM) |
| NZ (1) | NZ519230A (OSRAM) |
| PL (1) | PL201422B1 (OSRAM) |
| PT (3) | PT1690536E (OSRAM) |
| SI (3) | SI1230209T1 (OSRAM) |
| SK (3) | SK288185B6 (OSRAM) |
| UA (2) | UA73324C2 (OSRAM) |
| WO (1) | WO2001035957A1 (OSRAM) |
| ZA (1) | ZA200203315B (OSRAM) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0957073A1 (en) * | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| DE29923134U1 (de) * | 1999-11-16 | 2000-06-29 | Schwarz Pharma Ag, 40789 Monheim | Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen |
| DE10028443C1 (de) * | 2000-06-14 | 2002-05-29 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen |
| DE10315917A1 (de) * | 2003-04-08 | 2004-11-18 | Schwarz Pharma Ag | Hochreine Basen von 3,3-Diphenylpropylaminmonoestern |
| DE10315878B4 (de) | 2003-04-08 | 2009-06-04 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Fesoterodin und Verwendung |
| WO2005012227A2 (en) * | 2003-08-05 | 2005-02-10 | Ranbaxy Laboratories Limited | Process for preparation of 2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethyl-phenol, a metabolite of tolterodine |
| ES2235648B1 (es) * | 2003-12-22 | 2006-11-01 | Ragactives, S.L. | Procedimiento para la obtencion de tolterodina. |
| US8034823B2 (en) * | 2005-02-22 | 2011-10-11 | Savvipharm Inc | Method of increasing drug oral bioavailability and compositions of less toxic orotate salts |
| KR100647068B1 (ko) | 2005-09-15 | 2006-11-23 | 하나제약 주식회사 | 라세믹ｎ,ｎ-디이소프로필-3-(2-히드록시-5-메틸페닐)-3-페닐프로판아민의 제조방법 |
| DK2029567T3 (da) * | 2006-05-24 | 2010-11-29 | Pfizer Ltd | Fremgangsmåde til frembringelse af benzopyran-2-ol-derivater |
| AU2007267371B2 (en) * | 2006-05-31 | 2012-09-20 | Schwarz Pharma Ltd. | New synthesis of substituted hydroxymethyl phenols |
| EP1862449A1 (en) * | 2006-05-31 | 2007-12-05 | Schwarz Pharma Ltd. | A shortened synthesis of substituted hydroxymethyl phenols |
| IES20060424A2 (en) * | 2006-06-08 | 2007-10-31 | Schwarz Pharma Ltd | Accelerated synthesis of (3-Diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)phenol and its phenolic monoesters |
| DE602007008389D1 (de) * | 2006-06-09 | 2010-09-23 | Schwarz Pharma Ltd | Synthese von phenolischen estern von hydroxymethylphenolen |
| US7807715B2 (en) | 2006-06-09 | 2010-10-05 | Ucb Pharma Gmbh | Pharmaceutical compositions comprising fesoterodine |
| BRPI0712865B1 (pt) * | 2006-06-09 | 2021-08-17 | Schwarz Pharma Ag | Composição farmacêutica estabilizada compreendendo fesoterodina, método para preparação da mesma e uso de uma substância |
| IES20060435A2 (en) * | 2006-06-12 | 2007-12-12 | Schwarz Pharma Ltd | Shortened synthesis using paraformaldehyde or trioxane |
| SI2027103T1 (sl) | 2006-06-12 | 2014-07-31 | Ucb Pharma Gmbh | Novi kiralni vmesni produkt, postopek za njegovo proizvodnjo in njega uporaba pri proizvodnji tolterodina, fesoterodina ali njih aktivnega metabolita |
| US20100217034A1 (en) * | 2007-09-21 | 2010-08-26 | Actavis Group Ptc Ehf | Process for the Preparation of Fesoterodine |
| WO2009044278A1 (en) * | 2007-10-01 | 2009-04-09 | Actavis Group Ptc Ehf | Amorphous fesoterodine fumarate |
| WO2009122303A2 (en) * | 2008-04-04 | 2009-10-08 | Actavis Group Ptc Ehf | Novel mandelate salt of fesoterodine |
| WO2010010464A2 (en) * | 2008-07-21 | 2010-01-28 | Actavis Group Ptc Ehf | Fesoterodine substantially free of dehydroxy impurity |
| IT1392082B1 (it) * | 2008-12-10 | 2012-02-09 | Chemi Spa | Nuove forme solide della fesoterodina fumarato |
| US9085507B2 (en) | 2009-05-11 | 2015-07-21 | Ratiopharm Gmbh | Desfesoterodine in the form of a tartaric acid salt |
| IT1394219B1 (it) | 2009-05-15 | 2012-06-01 | Chemi Spa | Metodo di preparazione di fesoterodina fumarato di elevata purezza. |
| IT1394217B1 (it) * | 2009-05-15 | 2012-06-01 | Chemi Spa | Metodo di preparazione di fesoterodina e/o fesoterodina fumarato. |
| WO2011029005A1 (en) | 2009-09-03 | 2011-03-10 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Crystalline forms of fesoterodine fumarate and fesoterodine base |
| IT1396373B1 (it) * | 2009-10-29 | 2012-11-19 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina. |
| EP2316432A1 (de) | 2009-10-30 | 2011-05-04 | ratiopharm GmbH | Zusammensetzung enthaltend Fesoterodin und Ballaststoffe |
| US20110124903A1 (en) * | 2009-11-20 | 2011-05-26 | Actavis Group Ptc Ehf | Solid state forms of fesoterodine intermediates |
| IT1397521B1 (it) * | 2009-12-21 | 2013-01-16 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina con un basso contenuto di impurezze. |
| IT1397920B1 (it) * | 2010-02-08 | 2013-02-04 | Dipharma Francis Srl | Forma cristallina di fesoterodina fumarato e procedimento per la sua preparazione |
| EP2549985A1 (en) | 2010-03-22 | 2013-01-30 | Cadila Healthcare Limited | Stable pharmaceutical compositions comprising fesoterodine |
| US8748433B2 (en) | 2010-04-30 | 2014-06-10 | Merck Sharp & Dohme Corp. | β3 adrenergic receptor agonists |
| WO2011141932A2 (en) | 2010-05-11 | 2011-11-17 | Intas Pharmaceuticals Limited | Process for preparation of phenolic monoesters of hydroxymethyl phenols |
| WO2011145019A1 (en) * | 2010-05-17 | 2011-11-24 | Orchid Chemicals And Pharmaceuticals Limited | Improved process for diphenylpropylamine derivatives |
| IT1401451B1 (it) | 2010-06-10 | 2013-07-26 | Chemi Spa | Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. |
| WO2011158257A1 (en) | 2010-06-18 | 2011-12-22 | Panacea Biotec Ltd | Preparation process of fesoterodine and intermediates |
| WO2012025941A2 (en) | 2010-08-25 | 2012-03-01 | Cadila Healthcare Limited | Processes for the preparation of fesoterodine |
| IT1403094B1 (it) * | 2010-12-09 | 2013-10-04 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina o un suo sale |
| WO2012098560A2 (en) * | 2011-01-17 | 2012-07-26 | Msn Laboratories Limited | Process for the preparation of muscarinic receptor antagonist |
| TWI590821B (zh) | 2011-01-18 | 2017-07-11 | 輝瑞有限公司 | 固體分子分散液 |
| EP2508175A1 (en) | 2011-04-08 | 2012-10-10 | LEK Pharmaceuticals d.d. | Pharmaceutical composition comprising fesoterodine or a salt or a solvate thereof |
| EP2508173A1 (en) | 2011-04-08 | 2012-10-10 | LEK Pharmaceuticals d.d. | Stabilized pharmaceutical composition comprising fesoterodine |
| US9422228B2 (en) | 2012-05-04 | 2016-08-23 | Crystal Pharma, S.A.U. | Process for the preparation of optically pure fesoterodine derivatives |
| ITMI20121232A1 (it) | 2012-07-16 | 2014-01-17 | Cambrex Profarmaco Milano Srl | Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati |
| TR201721437A2 (tr) | 2017-12-25 | 2019-07-22 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Fesoterodi̇ni̇n modi̇fi̇ye salim sağlayan formülasyonlari |
| CN116472262A (zh) * | 2020-10-27 | 2023-07-21 | 威娜德国有限责任公司 | 化妆品级品质的2-甲氧基甲基-对苯二胺 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1181430A (en) * | 1980-11-14 | 1985-01-22 | Bennie J. Foster | (-) - n-methyl-3-(2-methylphenox)-3-phenylpropylamine, antidepressant |
| IL66831A0 (en) * | 1981-10-05 | 1982-12-31 | Kefalas As | Indane derivatives |
| SE8800207D0 (sv) * | 1988-01-22 | 1988-01-22 | Kabivitrum Ab | Nya aminer, deras anvendning och framstellning |
| EP0445749B1 (en) * | 1990-03-08 | 1996-07-10 | Fujisawa Pharmaceutical Co., Ltd. | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments |
| JPH0483431A (ja) * | 1990-07-26 | 1992-03-17 | Seiko Epson Corp | 選択呼出受信機 |
| SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
| SE9701144D0 (sv) * | 1997-03-27 | 1997-03-27 | Pharmacia & Upjohn Ab | Novel compounds, their use and preparation |
| EP0957073A1 (en) | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| DE29923134U1 (de) * | 1999-11-16 | 2000-06-29 | Schwarz Pharma Ag, 40789 Monheim | Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen |
-
1999
- 1999-11-16 DE DE29923134U patent/DE29923134U1/de not_active Expired - Lifetime
- 1999-11-16 DE DE19955190A patent/DE19955190A1/de not_active Ceased
-
2000
- 2000-11-15 EA EA200200511A patent/EA005588B1/ru not_active IP Right Cessation
- 2000-11-15 DK DK06011207T patent/DK1690536T3/da active
- 2000-11-15 IL IL14956700A patent/IL149567A0/xx unknown
- 2000-11-15 SK SK5027-2010A patent/SK288185B6/sk not_active IP Right Cessation
- 2000-11-15 CZ CZ20060247A patent/CZ302497B6/cs not_active IP Right Cessation
- 2000-11-15 WO PCT/EP2000/011309 patent/WO2001035957A1/de not_active Ceased
- 2000-11-15 AT AT06011207T patent/ATE395056T1/de active
- 2000-11-15 DE DE50009239T patent/DE50009239D1/de not_active Expired - Lifetime
- 2000-11-15 KR KR1020057018318A patent/KR100563149B1/ko not_active Expired - Lifetime
- 2000-11-15 SK SK5024-2013A patent/SK288384B6/sk not_active IP Right Cessation
- 2000-11-15 KR KR10-2002-7006306A patent/KR100536095B1/ko not_active Expired - Fee Related
- 2000-11-15 CA CA002389749A patent/CA2389749C/en not_active Expired - Lifetime
- 2000-11-15 PL PL356766A patent/PL201422B1/pl unknown
- 2000-11-15 AU AU26667/01A patent/AU778132B2/en not_active Expired
- 2000-11-15 SK SK657-2002A patent/SK287430B6/sk not_active IP Right Cessation
- 2000-11-15 ES ES04018487T patent/ES2270240T3/es not_active Expired - Lifetime
- 2000-11-15 EP EP00989857A patent/EP1230209B3/de not_active Expired - Lifetime
- 2000-11-15 UA UA2002043609A patent/UA73324C2/uk unknown
- 2000-11-15 HU HU0900587A patent/HU227608B1/hu unknown
- 2000-11-15 SI SI200030617T patent/SI1230209T1/xx unknown
- 2000-11-15 SI SI200030890T patent/SI1481964T1/sl unknown
- 2000-11-15 EP EP04018487A patent/EP1481964B1/de not_active Expired - Lifetime
- 2000-11-15 AT AT00989857T patent/ATE286872T1/de active
- 2000-11-15 HK HK02106545.5A patent/HK1045148B/zh not_active IP Right Cessation
- 2000-11-15 BR BRPI0015610A patent/BRPI0015610C1/pt not_active IP Right Cessation
- 2000-11-15 PT PT06011207T patent/PT1690536E/pt unknown
- 2000-11-15 CZ CZ20021343A patent/CZ302967B6/cs not_active IP Right Cessation
- 2000-11-15 JP JP2001537950A patent/JP4083431B2/ja not_active Expired - Lifetime
- 2000-11-15 MX MXPA02004603A patent/MXPA02004603A/es active IP Right Grant
- 2000-11-15 CN CNB008157057A patent/CN1215045C/zh not_active Expired - Lifetime
- 2000-11-15 DE DE50015163T patent/DE50015163D1/de not_active Expired - Lifetime
- 2000-11-15 DK DK04018487T patent/DK1481964T3/da active
- 2000-11-15 HU HU0204034A patent/HU228197B1/hu unknown
- 2000-11-15 EP EP06011207A patent/EP1690536B1/de not_active Expired - Lifetime
- 2000-11-15 DE DE50013365T patent/DE50013365D1/de not_active Expired - Lifetime
- 2000-11-15 PT PT00989857T patent/PT1230209E/pt unknown
- 2000-11-15 NZ NZ519230A patent/NZ519230A/en not_active IP Right Cessation
- 2000-11-15 ES ES00989857T patent/ES2236032T7/es active Active
- 2000-11-15 US US10/130,214 patent/US6858650B1/en not_active Expired - Lifetime
- 2000-11-15 PT PT04018487T patent/PT1481964E/pt unknown
- 2000-11-15 ES ES06011207T patent/ES2303708T3/es not_active Expired - Lifetime
- 2000-11-15 SI SI200030998T patent/SI1690536T1/sl unknown
- 2000-11-15 DK DK00989857T patent/DK1230209T3/da active
- 2000-11-15 AT AT04018487T patent/ATE337293T1/de active
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2002
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2005
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2006
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2007
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2008
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2010
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2011
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2013
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