DK1228028T3 - Hydroxyicosatetraenoatsalte, præparater og fremgangsmåder til anvendelse til behandling af öjentörhedslidelser - Google Patents

Hydroxyicosatetraenoatsalte, præparater og fremgangsmåder til anvendelse til behandling af öjentörhedslidelser

Info

Publication number
DK1228028T3
DK1228028T3 DK00972338T DK00972338T DK1228028T3 DK 1228028 T3 DK1228028 T3 DK 1228028T3 DK 00972338 T DK00972338 T DK 00972338T DK 00972338 T DK00972338 T DK 00972338T DK 1228028 T3 DK1228028 T3 DK 1228028T3
Authority
DK
Denmark
Prior art keywords
hydroxyicosatetraenoate
preparations
salts
treatment
methods
Prior art date
Application number
DK00972338T
Other languages
Danish (da)
English (en)
Inventor
L Wayne Schneider
Raymond E Conrow
Daniel A Gamache
Terri Pasquine
John M Yanni
Haresh G Bhagat
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of DK1228028T3 publication Critical patent/DK1228028T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK00972338T 1999-11-09 2000-10-23 Hydroxyicosatetraenoatsalte, præparater og fremgangsmåder til anvendelse til behandling af öjentörhedslidelser DK1228028T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16437099P 1999-11-09 1999-11-09
US16438299P 1999-11-09 1999-11-09
US16438499P 1999-11-09 1999-11-09

Publications (1)

Publication Number Publication Date
DK1228028T3 true DK1228028T3 (da) 2005-11-14

Family

ID=27389012

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00972338T DK1228028T3 (da) 1999-11-09 2000-10-23 Hydroxyicosatetraenoatsalte, præparater og fremgangsmåder til anvendelse til behandling af öjentörhedslidelser

Country Status (20)

Country Link
US (1) US6429227B1 (zh)
EP (1) EP1228028B1 (zh)
JP (1) JP2003513949A (zh)
KR (1) KR20020050240A (zh)
CN (1) CN1387503A (zh)
AR (1) AR032607A1 (zh)
AT (1) ATE301630T1 (zh)
AU (1) AU776187B2 (zh)
BR (1) BR0015436A (zh)
CA (1) CA2388044A1 (zh)
DE (1) DE60021908T2 (zh)
DK (1) DK1228028T3 (zh)
ES (1) ES2242643T3 (zh)
HK (1) HK1045302B (zh)
MX (1) MXPA02004701A (zh)
PL (1) PL356093A1 (zh)
PT (1) PT1228028E (zh)
TR (1) TR200201250T2 (zh)
TW (1) TWI283176B (zh)
WO (1) WO2001034549A1 (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002034246A2 (en) * 2000-10-23 2002-05-02 Alcon, Inc. Use of hydroperoxyeicosatetraenoic acid derivatives following refractive surgery
WO2003030894A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
WO2003030892A1 (en) * 2001-10-11 2003-04-17 Alcon, Inc. Methods for treating dry eye
US6825232B2 (en) * 2002-06-14 2004-11-30 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
WO2003105823A1 (en) * 2002-06-14 2003-12-24 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat dry mouth
US20030236284A1 (en) * 2002-06-14 2003-12-25 Alcon, Inc. Use of hydroxyeicosatetraenoic acid compounds to treat vaginal dryness
US20040002514A1 (en) * 2002-06-14 2004-01-01 Alcon, Inc. Topical use of hydroxyeicosatetraenoic acid compounds to treat psoriasis
MXPA05003063A (es) * 2002-09-20 2005-05-27 Alcon Inc Uso de inhibidores de la sintesis de citosina para el tratamiento de trastornos de ojos secos.
BR0306662A (pt) * 2002-10-18 2005-02-22 Joel S Echols Formulação lacrimal de três camadas
US20050187192A1 (en) * 2004-02-20 2005-08-25 Kucera Pharmaceutical Company Phospholipids for the treatment of infection by togaviruses, herpes viruses and coronaviruses
SI2574341T1 (sl) 2004-03-29 2017-08-31 University Of South Florida Učinkovito zdravljenje tumorjev in raka s triciribin fosfatom
KR100642425B1 (ko) * 2004-07-09 2006-11-03 (유) 이도건설 친수호안 구조
EP1793836A4 (en) * 2004-10-01 2008-09-03 Richard L Lindstrom OPHTHALMIC COMPOSITIONS WITH LUBRICANTS, DETERMINANTS AND GLYCOSAMINOGLYCAN AND METHOD FOR THEIR USE
US7638142B2 (en) * 2005-10-12 2009-12-29 Vitamin Science, Inc. Therapeutic composition for the treatment of dry eye syndrome
WO2010064636A1 (ja) * 2008-12-02 2010-06-10 ロート製薬株式会社 眼科用組成物
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
RU2599036C2 (ru) * 2011-01-26 2016-10-10 Аллерган, Инк. Андрогенная композиция для лечения офтальмологического заболевания
IL212725A (en) * 2011-05-05 2016-06-30 Resdevco Res And Dev Co Glycerol Preparation for Non-surgical Conjunctivochalysis
BR112015018414B1 (pt) * 2013-02-01 2022-11-08 Allergan, Inc Lágrimas artificiais compreendendo hialuronato de sódio e carboximetilcelulose
CN109232278A (zh) * 2013-11-15 2019-01-18 Ds生物制药有限公司 多不饱和羟基脂肪酸的药学上可接受的盐

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991759A (en) 1975-10-28 1976-11-16 Alza Corporation Method and therapeutic system for treating aqueous deficient dry eye
US4131651A (en) 1977-10-25 1978-12-26 Barnes-Hind Pharmaceuticals, Inc. Treatment of dry eye
US4409205A (en) 1979-03-05 1983-10-11 Cooper Laboratories, Inc. Ophthalmic solution
US4370325A (en) 1979-03-30 1983-01-25 Dermik Laboratories Pharmaceutical compositions and method of treatment
AU546872B2 (en) 1982-06-16 1985-09-26 Unilever Plc Skin treatment compositions containing a fatty acid or ester
US4421748A (en) 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
GB8319073D0 (en) 1983-07-14 1983-08-17 Efamol Ltd Fatty acid compositions
US4753945A (en) 1986-02-19 1988-06-28 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with phosphodiesterase inhibitors
US4868154A (en) 1986-02-19 1989-09-19 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with melanocyte stimulating hormones
US4744980A (en) 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4883658A (en) 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US4818537A (en) 1986-10-21 1989-04-04 Liposome Technology, Inc. Liposome composition for treating dry eye
US4966773A (en) 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
US5278151A (en) 1987-04-02 1994-01-11 Ocular Research Of Boston, Inc. Dry eye treatment solution
US4914088A (en) 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US4921644A (en) 1988-02-29 1990-05-01 Technology Unlimited, Inc. Mucin directed lipsome
US4906467A (en) 1988-03-24 1990-03-06 New York Medical College Novel, long-duration treatment for glaucoma
US4923700A (en) 1988-06-03 1990-05-08 Kaufman Herbert E Artificial tear suspension
US5064655A (en) 1989-02-24 1991-11-12 Liposome Technology, Inc. Liposome gel composition and method
US5075104A (en) 1989-03-31 1991-12-24 Alcon Laboratories, Inc. Ophthalmic carboxy vinyl polymer gel for dry eye syndrome
US5174988A (en) 1989-07-27 1992-12-29 Scientific Development & Research, Inc. Phospholipid delivery system
JPH05503527A (ja) 1990-02-22 1993-06-10 マクノート・ピーティーワイ・リミテッド 人工涙液
US5041434A (en) 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
ZA912797B (en) 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
ES2084722T3 (es) 1990-05-29 1996-05-16 Boston Ocular Res Composicion para tratamiento del ojo seco.
US5102670A (en) 1990-09-14 1992-04-07 Abraham Nader G Method for treating eye disorders by reducing 12(r)-hydroxyeicosatetraenoic acid and 12(r)-dihydroxyeicosatrienoic acid levels
JP2594486B2 (ja) 1991-01-15 1997-03-26 アルコン ラボラトリーズ インコーポレイテッド 局所的眼薬組成物
ZA927277B (en) 1991-10-02 1993-05-19 Boston Ocular Res Dry eye treatment process and solution.
EP0546728A3 (en) 1991-12-13 1993-09-08 Alcon Laboratories Inc Physiological tear compositions and methods for their preparation
ATE185697T1 (de) 1992-04-21 1999-11-15 Schepens Eye Res Inst Androgentherapie am auge beim sjögrensyndrom
US5290572A (en) 1992-08-06 1994-03-01 Deo Corporation Opthalmic composition for treating dry eye
US5358706A (en) 1992-09-30 1994-10-25 Union Carbide Chemicals & Plastics Technology Corporation Muco-adhesive polymers
US5455265A (en) 1993-02-11 1995-10-03 Allergan, Inc. Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors
US5389383A (en) 1993-06-18 1995-02-14 Allergan, Inc. Method for treating hypoxia-associated ocular complications
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
ATE244572T1 (de) 1996-10-15 2003-07-15 Liposome Co Inc Peptid-lipid konjugate, liposomen und liposomale arzneimittelverabreichung
US5800807A (en) 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
JP2002538124A (ja) 1999-03-01 2002-11-12 ヴィスタ サイエンティフィック エルエルシー ムチンを含む眼科用調合物

Also Published As

Publication number Publication date
DE60021908D1 (de) 2005-09-15
TWI283176B (en) 2007-07-01
ATE301630T1 (de) 2005-08-15
TR200201250T2 (tr) 2002-09-23
AU1101401A (en) 2001-06-06
PT1228028E (pt) 2005-10-31
AR032607A1 (es) 2003-11-19
MXPA02004701A (es) 2004-09-10
PL356093A1 (en) 2004-06-14
BR0015436A (pt) 2002-07-16
KR20020050240A (ko) 2002-06-26
WO2001034549A1 (en) 2001-05-17
HK1045302B (zh) 2005-10-14
EP1228028A1 (en) 2002-08-07
JP2003513949A (ja) 2003-04-15
CA2388044A1 (en) 2001-05-17
CN1387503A (zh) 2002-12-25
DE60021908T2 (de) 2006-04-06
ES2242643T3 (es) 2005-11-16
HK1045302A1 (en) 2002-11-22
US6429227B1 (en) 2002-08-06
AU776187B2 (en) 2004-09-02
EP1228028B1 (en) 2005-08-10

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