DK1201659T3 - Fremgangsmåde til fremstilling af N-carboxyanhydrider - Google Patents

Fremgangsmåde til fremstilling af N-carboxyanhydrider

Info

Publication number
DK1201659T3
DK1201659T3 DK01402707T DK01402707T DK1201659T3 DK 1201659 T3 DK1201659 T3 DK 1201659T3 DK 01402707 T DK01402707 T DK 01402707T DK 01402707 T DK01402707 T DK 01402707T DK 1201659 T3 DK1201659 T3 DK 1201659T3
Authority
DK
Denmark
Prior art keywords
carboxyanhydrides
preparation
reaction
atoms
nca
Prior art date
Application number
DK01402707T
Other languages
Danish (da)
English (en)
Inventor
Fabrice Cornille
Jean-Luc Copier
Jean-Pierre Senet
Yves Robin
Original Assignee
Isochem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isochem Sa filed Critical Isochem Sa
Application granted granted Critical
Publication of DK1201659T3 publication Critical patent/DK1201659T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK01402707T 2000-10-30 2001-10-19 Fremgangsmåde til fremstilling af N-carboxyanhydrider DK1201659T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0013906A FR2815962B1 (fr) 2000-10-30 2000-10-30 Procede de preparation des n-carboxyanhydrides

Publications (1)

Publication Number Publication Date
DK1201659T3 true DK1201659T3 (da) 2004-09-13

Family

ID=8855887

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01402707T DK1201659T3 (da) 2000-10-30 2001-10-19 Fremgangsmåde til fremstilling af N-carboxyanhydrider

Country Status (15)

Country Link
US (1) US6479665B2 (ja)
EP (1) EP1201659B1 (ja)
JP (1) JP4203786B2 (ja)
KR (1) KR100772349B1 (ja)
CN (1) CN1195746C (ja)
AT (1) ATE267181T1 (ja)
CA (1) CA2360033C (ja)
DE (1) DE60103345T2 (ja)
DK (1) DK1201659T3 (ja)
ES (1) ES2220692T3 (ja)
FR (1) FR2815962B1 (ja)
HK (1) HK1046408B (ja)
HU (1) HU228392B1 (ja)
IL (1) IL146008A (ja)
SG (1) SG101497A1 (ja)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2828195B1 (fr) * 2001-05-31 2003-12-26 Isochem Sa Procede de preparation des n-carboxyanhydrides
FR2846326A1 (fr) * 2002-10-29 2004-04-30 Isochem Sa Procede de purification des n-carboxyanhydrides
US7317070B1 (en) 2004-03-12 2008-01-08 Sigma-Aldrich Co. Process for the preparation of polyamino acids
WO2006027788A1 (en) * 2004-09-06 2006-03-16 Biocon Limited Process for the preparation of n-carboxyanhydrides
DE602005025521D1 (de) * 2004-10-26 2011-02-03 Sigma Aldrich Co Synthese von aminosäure-n-carboxyanhydriden
FR2928372B1 (fr) * 2008-03-10 2010-12-31 Solvay Procede de synthese peptidique
HUE025042T2 (en) * 2008-08-07 2016-07-28 Sigma Aldrich Co Llc High-yield production of low molecular weight polylysine and poliornitine
EP2406300B1 (en) 2009-03-10 2016-11-16 Sigma-Aldrich Co. LLC Method for the production of polyamino acid random copolymers
CN101684078B (zh) * 2009-08-24 2013-01-16 浙江工业大学 2-氨基丁酰胺盐酸盐的化学合成方法
NO2635592T3 (ja) 2010-11-03 2018-01-13
WO2012067974A1 (en) * 2010-11-17 2012-05-24 Sigma-Aldrich Co. Llc. A greener method for the production of copolymer 1
EP2690097B1 (en) * 2011-03-25 2017-05-17 Nippon Soda Co., Ltd. Method for crystallizing glutamic acid benzyl ester n-carboxylic anhydride
CN103335873B (zh) * 2013-06-04 2017-04-19 深圳翰宇药业股份有限公司 测量氨基酸‑n‑甲酸酐中氯离子含量的方法
CN104777114A (zh) * 2015-04-10 2015-07-15 合肥安德生制药有限公司 一种氨基酸-n-甲酸酐中氯离子的测定方法
JP6995695B2 (ja) 2018-05-25 2022-01-17 信越化学工業株式会社 アミノ酸ｎ－カルボキシ無水物の精製方法
WO2020064904A1 (en) 2018-09-28 2020-04-02 Lonza Ltd Method for preparation of n-carboxyanhydrides
CN114634460A (zh) * 2020-12-16 2022-06-17 北京大学 羧基环内酸酐的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1012498A (en) * 1963-07-23 1965-12-08 Ajinomoto Kk A process for preparing ª†-methyl glutamate n-carboxy anhydride
GB1189261A (en) 1967-01-21 1970-04-22 Kyowa Hakko Kogyo Kk Process for Producing N-Carboxy Anhydrides of Glutamic Acid-gamma-Esters
NL6808553A (ja) * 1967-06-30 1968-12-31
GB1208251A (en) * 1968-01-12 1970-10-14 Kyowa Hakko Kogyo Kk PROCESS FOR THE PREPARATION OF N-CARBOXYLIC ACID ANHYDRIDES OF GLUTAMIC ACID-gamma-ESTERS
US4496541A (en) * 1983-01-12 1985-01-29 Usv Pharmaceutical Corporation Compounds for treating hypertension
JPH0543560A (ja) * 1991-08-09 1993-02-23 Ajinomoto Co Inc 新規ｎ−カルボキシアミノ酸無水物及びこれを原料とするポリペプチドの製造法
SI9200213A (en) * 1992-09-16 1994-03-31 Krka Process for preparing alkyl-l-alanil-l-proline derivates
US6262274B1 (en) * 2000-10-13 2001-07-17 Everlight Usa, Inc. Process for preparing N-[1-(S)-ethyoxycarbonyl-3-phenylpropyl]-L-ananine N-carboxyanhydride

Also Published As

Publication number Publication date
DE60103345D1 (de) 2004-06-24
US6479665B2 (en) 2002-11-12
FR2815962B1 (fr) 2003-03-07
SG101497A1 (en) 2004-01-30
ES2220692T3 (es) 2004-12-16
KR100772349B1 (ko) 2007-11-02
CA2360033A1 (en) 2002-04-30
IL146008A (en) 2006-12-31
HU0104566D0 (en) 2002-01-28
HUP0104566A3 (en) 2002-12-28
HUP0104566A2 (hu) 2002-07-29
HU228392B1 (hu) 2013-03-28
JP4203786B2 (ja) 2009-01-07
EP1201659A1 (fr) 2002-05-02
FR2815962A1 (fr) 2002-05-03
EP1201659B1 (fr) 2004-05-19
JP2002145871A (ja) 2002-05-22
KR20020034896A (ko) 2002-05-09
ATE267181T1 (de) 2004-06-15
HK1046408B (zh) 2005-10-14
DE60103345T2 (de) 2005-06-16
CN1355166A (zh) 2002-06-26
US20020082431A1 (en) 2002-06-27
CN1195746C (zh) 2005-04-06
HK1046408A1 (en) 2003-01-10
CA2360033C (en) 2007-02-06

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