DK118249B - Fremgangsmåde til fremstilling af 1-substituerede 5-pyridyl-1,4-benzodiazepinderivater eller syreadditionssalte deraf. - Google Patents

Fremgangsmåde til fremstilling af 1-substituerede 5-pyridyl-1,4-benzodiazepinderivater eller syreadditionssalte deraf.

Info

Publication number
DK118249B
DK118249B DK65465AA DK65465A DK118249B DK 118249 B DK118249 B DK 118249B DK 65465A A DK65465A A DK 65465AA DK 65465 A DK65465 A DK 65465A DK 118249 B DK118249 B DK 118249B
Authority
DK
Denmark
Prior art keywords
pyridyl
substituted
preparation
acid addition
addition salts
Prior art date
Application number
DK65465AA
Other languages
Danish (da)
English (en)
Inventor
G Archer
R Fryer
E Reeder
L Sternbach
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23348328&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK118249(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK118249B publication Critical patent/DK118249B/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Supply And Distribution Of Alternating Current (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Multicomponent Fibers (AREA)
DK65465AA 1964-02-11 1965-02-09 Fremgangsmåde til fremstilling af 1-substituerede 5-pyridyl-1,4-benzodiazepinderivater eller syreadditionssalte deraf. DK118249B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US343941A US3299053A (en) 1964-02-11 1964-02-11 Novel 1-and/or 4-substituted alkyl 5-aromatic-3h-1, 4-benzodiazepines and benzodiazepine-2-ones

Publications (1)

Publication Number Publication Date
DK118249B true DK118249B (da) 1970-07-27

Family

ID=23348328

Family Applications (3)

Application Number Title Priority Date Filing Date
DK65465AA DK118249B (da) 1964-02-11 1965-02-09 Fremgangsmåde til fremstilling af 1-substituerede 5-pyridyl-1,4-benzodiazepinderivater eller syreadditionssalte deraf.
DK69265AA DK105984C (da) 1964-02-11 1965-02-10 Fremgangsmåde til fremstilling af 1,5-disubstituerede 1,4-benzodiazepinderivater eller syreadditionssalte deraf.
DK69165AA DK107032C (da) 1964-02-11 1965-02-10 Fremgangsmåde til fremstilling af 1-(3-dimethylamino-propyl)-7-chlor-5-(2-fluor-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on eller syreadditionssalte deraf.

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK69265AA DK105984C (da) 1964-02-11 1965-02-10 Fremgangsmåde til fremstilling af 1,5-disubstituerede 1,4-benzodiazepinderivater eller syreadditionssalte deraf.
DK69165AA DK107032C (da) 1964-02-11 1965-02-10 Fremgangsmåde til fremstilling af 1-(3-dimethylamino-propyl)-7-chlor-5-(2-fluor-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on eller syreadditionssalte deraf.

Country Status (13)

Country Link
US (1) US3299053A (es)
BE (4) BE659443A (es)
BR (4) BR6567053D0 (es)
CH (4) CH460793A (es)
DE (4) DE1545933A1 (es)
DK (3) DK118249B (es)
ES (4) ES309169A1 (es)
FR (6) FR4123M (es)
GB (4) GB1098242A (es)
IL (4) IL22869A (es)
NL (4) NL6501578A (es)
NO (3) NO117367B (es)
SE (4) SE307952B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO120269B (es) * 1965-11-02 1970-09-28 Hoffmann La Roche
US3464978A (en) * 1967-04-21 1969-09-02 Hoffmann La Roche 1-substituted urea alkyl 1,2-dihydro-1,4-benzodiazepines and benzodiazepin - 2-ones
US3523939A (en) * 1967-07-03 1970-08-11 Hoffmann La Roche 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation
US3506403A (en) * 1967-12-19 1970-04-14 Hoffmann La Roche Colorimetric method for determining iron in fluids
US3506404A (en) * 1967-12-19 1970-04-14 Hoffmann La Roche Colorimetric method for determining iron in blood
US3609146A (en) * 1968-11-01 1971-09-28 Sandoz Ag Substituted benzodiazepinone derivatives
IL33961A (en) * 1969-03-13 1973-03-30 Sparamedica Ag Benzodiazepine aminoalkyl carboxylates,their preparation and pharmaceutical compositions containing them
US3691157A (en) * 1970-08-12 1972-09-12 Rodney Ian Fryer Preparation of 7-substituted-1-(2-diethylaminoethyl)-5-(2-halophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-ones
AT314541B (de) * 1970-10-19 1974-04-10 Sumitomo Chemical Co Verfahren zur Herstellung von neuen Benzodiazepinen und ihren Salzen
US3678038A (en) * 1971-04-01 1972-07-18 Hoffmann La Roche 1,4-benzodiazepin-5-ones and methods for the preparation thereof
US3856802A (en) * 1971-05-10 1974-12-24 Upjohn Co 1,6-DISUBSTITUTED-4H-5-{8 4,3-a{9 BENZODIAZEPINES
US3872089A (en) * 1971-05-14 1975-03-18 Hoffmann La Roche Substituted thienodiazepines
US4008223A (en) * 1971-12-09 1977-02-15 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
USRE31071E (en) * 1971-12-09 1982-11-02 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
US3859276A (en) * 1972-12-13 1975-01-07 Merck & Co Inc 7-chloro-1,3-dihydro-5-2-polyfluoroalkoxyphenyl)-2h-1,4-benzodiazepin-2-ones
GB1414370A (en) * 1973-08-24 1975-11-19 Grindstedvaerket As Benzodiazepines and their production
US4232016A (en) * 1974-12-20 1980-11-04 Merck Patent Gesellschaft Mit Beschraenkter Haftung 3-Fluorobenzodiazepines
US4246270A (en) * 1976-05-26 1981-01-20 E. I. Du Pont De Nemours And Company 3-Fluorobenzodiazepines and compositions and uses thereof
DE2852606A1 (de) * 1977-12-14 1979-06-21 Gerot Pharmazeutika 3-di-n-propyl-acetoxy-benzodiazepin-2-one und verfahren zu deren herstellung
AT361492B (de) * 1978-12-18 1981-03-10 Gerot Pharmazeutika Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen
US8530463B2 (en) * 2007-05-07 2013-09-10 Hale Biopharma Ventures Llc Multimodal particulate formulations
EP2146722A4 (en) 2007-05-10 2011-08-03 Amr Technology Inc ARYL AND HETEROARYL SUBSTITUTED TETRAHYDROBENZO-1,4-DIAZEPINES AND THEIR USE FOR BLOCKING THE RECOVERY OF NOREPINEPHRIN, DOPAMINE AND SEROTONINE
JP5613657B2 (ja) 2008-03-28 2014-10-29 ヘイル バイオファーマ ベンチャーズ，エルエルシー ベンゾジアゼピン組成物の投与
DK3415139T3 (da) 2011-06-14 2022-06-20 Neurelis Inc Administration af benzodiazepin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121076A (en) * 1964-02-11 Benzodiazepinones and processes
US3109843A (en) * 1963-11-05 Process for preparing
US2461038A (en) * 1947-05-15 1949-02-08 Searle & Co Chemical compositions and the preparation thereof
US2532292A (en) * 1947-12-12 1950-12-05 Searle & Co Diarylmethyl ethers of amino alkanols
US2576106A (en) * 1948-07-13 1951-11-27 Searle & Co N-dicyclohexyl, dialkylaminoalkanamides
US2687414A (en) * 1948-11-26 1954-08-24 Searle & Co Method for producing aromatic aminoalkyl amines

Also Published As

Publication number Publication date
NL6501631A (es) 1965-08-12
IL22902A (en) 1969-01-29
NL6501632A (es) 1965-08-12
DE1545936A1 (de) 1969-12-18
SE309597B (es) 1969-03-31
BR6567055D0 (pt) 1973-08-02
FR4123M (es) 1966-04-25
SE307953B (es) 1969-01-27
BR6567054D0 (pt) 1973-08-14
BE659442A (es) 1965-08-09
FR4138M (es) 1966-05-02
ES309170A1 (es) 1965-07-16
BE659444A (es) 1965-08-09
FR4609M (es) 1966-11-21
GB1098242A (en) 1968-01-10
NL6501578A (es) 1965-08-12
ES309168A1 (es) 1965-10-01
NO118273B (es) 1969-12-08
FR4772M (es) 1967-01-23
GB1051795A (es)
FR1443116A (fr) 1966-06-24
BR6567051D0 (pt) 1973-08-14
CH458372A (de) 1968-06-30
SE321477B (es) 1970-03-09
DE1545935A1 (de) 1969-12-11
NO119798B (es) 1970-07-06
DE1545933A1 (de) 1969-12-18
NO117367B (es) 1969-08-04
NL141781B (nl) 1974-04-16
DK107032C (da) 1967-04-17
ES309169A1 (es) 1965-10-16
IL22935A (en) 1969-11-30
CH460030A (de) 1968-07-31
GB1077358A (en) 1967-07-26
DE1545934A1 (de) 1970-10-22
CH460793A (de) 1968-08-15
IL22903A (en) 1969-03-27
FR1455059A (fr) 1966-10-07
IL22869A (en) 1968-11-27
GB1052144A (es)
BE659443A (es) 1965-08-09
NL6501579A (es) 1965-08-12
DE1545936B2 (de) 1975-09-18
BE659445A (es) 1965-08-09
BR6567053D0 (pt) 1973-12-26
SE307952B (es) 1969-01-27
DK105984C (da) 1966-12-05
ES309167A2 (es) 1965-10-01
CH467787A (de) 1969-01-31
US3299053A (en) 1967-01-17

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