DK107032C - Fremgangsmåde til fremstilling af 1-(3-dimethylamino-propyl)-7-chlor-5-(2-fluor-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on eller syreadditionssalte deraf. - Google Patents
Fremgangsmåde til fremstilling af 1-(3-dimethylamino-propyl)-7-chlor-5-(2-fluor-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on eller syreadditionssalte deraf.Info
- Publication number
- DK107032C DK107032C DK69165AA DK69165A DK107032C DK 107032 C DK107032 C DK 107032C DK 69165A A DK69165A A DK 69165AA DK 69165 A DK69165 A DK 69165A DK 107032 C DK107032 C DK 107032C
- Authority
- DK
- Denmark
- Prior art keywords
- benzodiazepin
- dihydro
- dimethylamino
- fluoro
- chloro
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Multicomponent Fibers (AREA)
- Supply And Distribution Of Alternating Current (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US343941A US3299053A (en) | 1964-02-11 | 1964-02-11 | Novel 1-and/or 4-substituted alkyl 5-aromatic-3h-1, 4-benzodiazepines and benzodiazepine-2-ones |
Publications (1)
Publication Number | Publication Date |
---|---|
DK107032C true DK107032C (da) | 1967-04-17 |
Family
ID=23348328
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK65465AA DK118249B (da) | 1964-02-11 | 1965-02-09 | Fremgangsmåde til fremstilling af 1-substituerede 5-pyridyl-1,4-benzodiazepinderivater eller syreadditionssalte deraf. |
DK69165AA DK107032C (da) | 1964-02-11 | 1965-02-10 | Fremgangsmåde til fremstilling af 1-(3-dimethylamino-propyl)-7-chlor-5-(2-fluor-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on eller syreadditionssalte deraf. |
DK69265AA DK105984C (da) | 1964-02-11 | 1965-02-10 | Fremgangsmåde til fremstilling af 1,5-disubstituerede 1,4-benzodiazepinderivater eller syreadditionssalte deraf. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK65465AA DK118249B (da) | 1964-02-11 | 1965-02-09 | Fremgangsmåde til fremstilling af 1-substituerede 5-pyridyl-1,4-benzodiazepinderivater eller syreadditionssalte deraf. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK69265AA DK105984C (da) | 1964-02-11 | 1965-02-10 | Fremgangsmåde til fremstilling af 1,5-disubstituerede 1,4-benzodiazepinderivater eller syreadditionssalte deraf. |
Country Status (13)
Country | Link |
---|---|
US (1) | US3299053A (da) |
BE (4) | BE659444A (da) |
BR (4) | BR6567053D0 (da) |
CH (4) | CH460793A (da) |
DE (4) | DE1545933A1 (da) |
DK (3) | DK118249B (da) |
ES (4) | ES309168A1 (da) |
FR (6) | FR4123M (da) |
GB (4) | GB1077358A (da) |
IL (4) | IL22869A (da) |
NL (4) | NL6501578A (da) |
NO (3) | NO117367B (da) |
SE (4) | SE309597B (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO120269B (da) * | 1965-11-02 | 1970-09-28 | Hoffmann La Roche | |
US3464978A (en) * | 1967-04-21 | 1969-09-02 | Hoffmann La Roche | 1-substituted urea alkyl 1,2-dihydro-1,4-benzodiazepines and benzodiazepin - 2-ones |
US3523939A (en) * | 1967-07-03 | 1970-08-11 | Hoffmann La Roche | 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation |
US3506404A (en) * | 1967-12-19 | 1970-04-14 | Hoffmann La Roche | Colorimetric method for determining iron in blood |
US3506403A (en) * | 1967-12-19 | 1970-04-14 | Hoffmann La Roche | Colorimetric method for determining iron in fluids |
US3609146A (en) * | 1968-11-01 | 1971-09-28 | Sandoz Ag | Substituted benzodiazepinone derivatives |
IL33961A (en) * | 1969-03-13 | 1973-03-30 | Sparamedica Ag | Benzodiazepine aminoalkyl carboxylates,their preparation and pharmaceutical compositions containing them |
US3691157A (en) * | 1970-08-12 | 1972-09-12 | Rodney Ian Fryer | Preparation of 7-substituted-1-(2-diethylaminoethyl)-5-(2-halophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-ones |
AT314541B (de) * | 1970-10-19 | 1974-04-10 | Sumitomo Chemical Co | Verfahren zur Herstellung von neuen Benzodiazepinen und ihren Salzen |
US3678038A (en) * | 1971-04-01 | 1972-07-18 | Hoffmann La Roche | 1,4-benzodiazepin-5-ones and methods for the preparation thereof |
US3856802A (en) * | 1971-05-10 | 1974-12-24 | Upjohn Co | 1,6-DISUBSTITUTED-4H-5-{8 4,3-a{9 BENZODIAZEPINES |
US3872089A (en) * | 1971-05-14 | 1975-03-18 | Hoffmann La Roche | Substituted thienodiazepines |
US4008223A (en) * | 1971-12-09 | 1977-02-15 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler | 6-Aza-3H-1,4-benzodiazepines |
USRE31071E (en) * | 1971-12-09 | 1982-11-02 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler | 6-Aza-3H-1,4-benzodiazepines |
US3859276A (en) * | 1972-12-13 | 1975-01-07 | Merck & Co Inc | 7-chloro-1,3-dihydro-5-2-polyfluoroalkoxyphenyl)-2h-1,4-benzodiazepin-2-ones |
GB1414370A (en) * | 1973-08-24 | 1975-11-19 | Grindstedvaerket As | Benzodiazepines and their production |
US4232016A (en) * | 1974-12-20 | 1980-11-04 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | 3-Fluorobenzodiazepines |
US4246270A (en) * | 1976-05-26 | 1981-01-20 | E. I. Du Pont De Nemours And Company | 3-Fluorobenzodiazepines and compositions and uses thereof |
FI783743A (fi) * | 1977-12-14 | 1979-06-15 | Gerot Pharmazeutika | Foerfarande foer framstaellning av 3-di-n-propyl-acetoxi-benzodiazepin-2-oner |
AT361492B (de) * | 1978-12-18 | 1981-03-10 | Gerot Pharmazeutika | Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen |
US8530463B2 (en) * | 2007-05-07 | 2013-09-10 | Hale Biopharma Ventures Llc | Multimodal particulate formulations |
KR20100017766A (ko) | 2007-05-10 | 2010-02-16 | 에이엠알 테크놀로지, 인크. | 아릴- 및 헤테로아릴-치환된 테트라히드로벤조-1,4-디아제핀 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 이의 용도 |
US20090258865A1 (en) * | 2008-03-28 | 2009-10-15 | Hale Biopharma Ventures, Llc | Administration of benzodiazepine compositions |
PL3415139T3 (pl) | 2011-06-14 | 2022-07-11 | Neurelis, Inc. | Podawanie benzodiazepiny |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3109843A (en) * | 1963-11-05 | Process for preparing | ||
US3121076A (en) * | 1964-02-11 | Benzodiazepinones and processes | ||
US2461038A (en) * | 1947-05-15 | 1949-02-08 | Searle & Co | Chemical compositions and the preparation thereof |
US2532292A (en) * | 1947-12-12 | 1950-12-05 | Searle & Co | Diarylmethyl ethers of amino alkanols |
US2576106A (en) * | 1948-07-13 | 1951-11-27 | Searle & Co | N-dicyclohexyl, dialkylaminoalkanamides |
US2687414A (en) * | 1948-11-26 | 1954-08-24 | Searle & Co | Method for producing aromatic aminoalkyl amines |
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0
- GB GB1052144D patent/GB1052144A/en active Active
- GB GB1051795D patent/GB1051795A/en active Active
-
1964
- 1964-02-11 US US343941A patent/US3299053A/en not_active Expired - Lifetime
-
1965
- 1965-01-25 CH CH332768A patent/CH460793A/de unknown
- 1965-01-25 CH CH102465A patent/CH460030A/de unknown
- 1965-01-28 CH CH118165A patent/CH467787A/de unknown
- 1965-01-28 DE DE19651545933 patent/DE1545933A1/de active Pending
- 1965-01-28 CH CH118265A patent/CH458372A/de unknown
- 1965-01-29 IL IL22869A patent/IL22869A/en unknown
- 1965-01-30 DE DE19651545934 patent/DE1545934A1/de active Pending
- 1965-02-01 DE DE1545936A patent/DE1545936B2/de active Pending
- 1965-02-01 DE DE19651545935 patent/DE1545935A1/de active Pending
- 1965-02-02 FR FR4021A patent/FR4123M/fr not_active Expired
- 1965-02-03 IL IL22902A patent/IL22902A/en unknown
- 1965-02-03 IL IL22903A patent/IL22903A/xx unknown
- 1965-02-05 SE SE1507/65A patent/SE309597B/xx unknown
- 1965-02-05 SE SE1508/65A patent/SE307952B/xx unknown
- 1965-02-06 FR FR4639A patent/FR1455059A/fr not_active Expired
- 1965-02-08 GB GB5288/65A patent/GB1077358A/en not_active Expired
- 1965-02-08 GB GB5289/65A patent/GB1098242A/en not_active Expired
- 1965-02-08 IL IL22935A patent/IL22935A/xx unknown
- 1965-02-09 BE BE659444D patent/BE659444A/xx unknown
- 1965-02-09 NL NL6501578A patent/NL6501578A/xx unknown
- 1965-02-09 BE BE659443D patent/BE659443A/xx unknown
- 1965-02-09 FR FR4800A patent/FR4138M/fr not_active Expired
- 1965-02-09 NO NO156707A patent/NO117367B/no unknown
- 1965-02-09 BE BE659442D patent/BE659442A/xx unknown
- 1965-02-09 FR FR4801A patent/FR1443116A/fr not_active Expired
- 1965-02-09 DK DK65465AA patent/DK118249B/da unknown
- 1965-02-09 SE SE1617/65A patent/SE307953B/xx unknown
- 1965-02-09 NL NL6501579A patent/NL6501579A/xx unknown
- 1965-02-09 BE BE659445D patent/BE659445A/xx unknown
- 1965-02-10 NO NO156722A patent/NO118273B/no unknown
- 1965-02-10 DK DK69165AA patent/DK107032C/da active
- 1965-02-10 NL NL6501631A patent/NL6501631A/xx unknown
- 1965-02-10 SE SE1688/65A patent/SE321477B/xx unknown
- 1965-02-10 BR BR167053/65A patent/BR6567053D0/pt unknown
- 1965-02-10 NL NL656501632A patent/NL141781B/xx unknown
- 1965-02-10 DK DK69265AA patent/DK105984C/da active
- 1965-02-10 ES ES0309168A patent/ES309168A1/es not_active Expired
- 1965-02-10 BR BR167054/65A patent/BR6567054D0/pt unknown
- 1965-02-10 ES ES0309170A patent/ES309170A1/es not_active Expired
- 1965-02-10 ES ES0309169A patent/ES309169A1/es not_active Expired
- 1965-02-10 NO NO156721A patent/NO119798B/no unknown
- 1965-02-10 BR BR167055/65A patent/BR6567055D0/pt unknown
- 1965-02-10 BR BR167051/65A patent/BR6567051D0/pt unknown
- 1965-02-10 ES ES0309167A patent/ES309167A2/es not_active Expired
- 1965-04-06 FR FR12017A patent/FR4772M/fr not_active Expired
- 1965-04-07 FR FR12188A patent/FR4609M/fr not_active Expired
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