DK105984C - Fremgangsmåde til fremstilling af 1,5-disubstituerede 1,4-benzodiazepinderivater eller syreadditionssalte deraf. - Google Patents

Fremgangsmåde til fremstilling af 1,5-disubstituerede 1,4-benzodiazepinderivater eller syreadditionssalte deraf.

Info

Publication number
DK105984C
DK105984C DK69265AA DK69265A DK105984C DK 105984 C DK105984 C DK 105984C DK 69265A A DK69265A A DK 69265AA DK 69265 A DK69265 A DK 69265A DK 105984 C DK105984 C DK 105984C
Authority
DK
Denmark
Prior art keywords
disubstituted
preparation
acid addition
addition salts
benzodiazepine derivatives
Prior art date
Application number
DK69265AA
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23348328&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK105984(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK105984C publication Critical patent/DK105984C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Supply And Distribution Of Alternating Current (AREA)
  • Multicomponent Fibers (AREA)
DK69265AA 1964-02-11 1965-02-10 Fremgangsmåde til fremstilling af 1,5-disubstituerede 1,4-benzodiazepinderivater eller syreadditionssalte deraf. DK105984C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US343941A US3299053A (en) 1964-02-11 1964-02-11 Novel 1-and/or 4-substituted alkyl 5-aromatic-3h-1, 4-benzodiazepines and benzodiazepine-2-ones

Publications (1)

Publication Number Publication Date
DK105984C true DK105984C (da) 1966-12-05

Family

ID=23348328

Family Applications (3)

Application Number Title Priority Date Filing Date
DK65465AA DK118249B (da) 1964-02-11 1965-02-09 Fremgangsmåde til fremstilling af 1-substituerede 5-pyridyl-1,4-benzodiazepinderivater eller syreadditionssalte deraf.
DK69265AA DK105984C (da) 1964-02-11 1965-02-10 Fremgangsmåde til fremstilling af 1,5-disubstituerede 1,4-benzodiazepinderivater eller syreadditionssalte deraf.
DK69165AA DK107032C (da) 1964-02-11 1965-02-10 Fremgangsmåde til fremstilling af 1-(3-dimethylamino-propyl)-7-chlor-5-(2-fluor-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on eller syreadditionssalte deraf.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK65465AA DK118249B (da) 1964-02-11 1965-02-09 Fremgangsmåde til fremstilling af 1-substituerede 5-pyridyl-1,4-benzodiazepinderivater eller syreadditionssalte deraf.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK69165AA DK107032C (da) 1964-02-11 1965-02-10 Fremgangsmåde til fremstilling af 1-(3-dimethylamino-propyl)-7-chlor-5-(2-fluor-phenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-on eller syreadditionssalte deraf.

Country Status (13)

Country Link
US (1) US3299053A (da)
BE (4) BE659443A (da)
BR (4) BR6567053D0 (da)
CH (4) CH460793A (da)
DE (4) DE1545933A1 (da)
DK (3) DK118249B (da)
ES (4) ES309170A1 (da)
FR (6) FR4123M (da)
GB (4) GB1098242A (da)
IL (4) IL22869A (da)
NL (4) NL6501579A (da)
NO (3) NO117367B (da)
SE (4) SE307952B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO120269B (da) * 1965-11-02 1970-09-28 Hoffmann La Roche
US3464978A (en) * 1967-04-21 1969-09-02 Hoffmann La Roche 1-substituted urea alkyl 1,2-dihydro-1,4-benzodiazepines and benzodiazepin - 2-ones
US3523939A (en) * 1967-07-03 1970-08-11 Hoffmann La Roche 5-(2,6-disubstituted phenyl)-1,4-benzodiazepines and methods for their preparation
US3506403A (en) * 1967-12-19 1970-04-14 Hoffmann La Roche Colorimetric method for determining iron in fluids
US3506404A (en) * 1967-12-19 1970-04-14 Hoffmann La Roche Colorimetric method for determining iron in blood
US3609146A (en) * 1968-11-01 1971-09-28 Sandoz Ag Substituted benzodiazepinone derivatives
DE2008612A1 (de) * 1969-03-13 1970-10-01 F. Hoffmann-La Roche & Co Ag, Basel (Schweiz) Benzodiazepin-Derivate
US3691157A (en) * 1970-08-12 1972-09-12 Rodney Ian Fryer Preparation of 7-substituted-1-(2-diethylaminoethyl)-5-(2-halophenyl)-1,3-dihydro-2h-1,4-benzodiazepin-2-ones
AT314541B (de) * 1970-10-19 1974-04-10 Sumitomo Chemical Co Verfahren zur Herstellung von neuen Benzodiazepinen und ihren Salzen
US3678038A (en) * 1971-04-01 1972-07-18 Hoffmann La Roche 1,4-benzodiazepin-5-ones and methods for the preparation thereof
US3856802A (en) * 1971-05-10 1974-12-24 Upjohn Co 1,6-DISUBSTITUTED-4H-5-{8 4,3-a{9 BENZODIAZEPINES
US3872089A (en) * 1971-05-14 1975-03-18 Hoffmann La Roche Substituted thienodiazepines
US4008223A (en) * 1971-12-09 1977-02-15 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
USRE31071E (en) * 1971-12-09 1982-11-02 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler 6-Aza-3H-1,4-benzodiazepines
US3859276A (en) * 1972-12-13 1975-01-07 Merck & Co Inc 7-chloro-1,3-dihydro-5-2-polyfluoroalkoxyphenyl)-2h-1,4-benzodiazepin-2-ones
GB1414370A (en) * 1973-08-24 1975-11-19 Grindstedvaerket As Benzodiazepines and their production
US4232016A (en) * 1974-12-20 1980-11-04 Merck Patent Gesellschaft Mit Beschraenkter Haftung 3-Fluorobenzodiazepines
US4246270A (en) * 1976-05-26 1981-01-20 E. I. Du Pont De Nemours And Company 3-Fluorobenzodiazepines and compositions and uses thereof
DE2852606A1 (de) * 1977-12-14 1979-06-21 Gerot Pharmazeutika 3-di-n-propyl-acetoxy-benzodiazepin-2-one und verfahren zu deren herstellung
AT361492B (de) * 1978-12-18 1981-03-10 Gerot Pharmazeutika Verfahren zur herstellung von neuen 3-hydroxy- 1,4-benzodiazepin-2-onen
US8530463B2 (en) * 2007-05-07 2013-09-10 Hale Biopharma Ventures Llc Multimodal particulate formulations
KR20100017766A (ko) 2007-05-10 2010-02-16 에이엠알 테크놀로지, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤조-1,4-디아제핀 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 이의 용도
ES2586032T3 (es) 2008-03-28 2016-10-11 Hale Biopharma Ventures, Llc Administración de composiciones de benzodiazepinas
CN103796656A (zh) 2011-06-14 2014-05-14 哈尔生物药投资有限责任公司 苯二氮卓的投与

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3121076A (en) * 1964-02-11 Benzodiazepinones and processes
US3109843A (en) * 1963-11-05 Process for preparing
US2461038A (en) * 1947-05-15 1949-02-08 Searle & Co Chemical compositions and the preparation thereof
US2532292A (en) * 1947-12-12 1950-12-05 Searle & Co Diarylmethyl ethers of amino alkanols
US2576106A (en) * 1948-07-13 1951-11-27 Searle & Co N-dicyclohexyl, dialkylaminoalkanamides
US2687414A (en) * 1948-11-26 1954-08-24 Searle & Co Method for producing aromatic aminoalkyl amines

Also Published As

Publication number Publication date
FR1455059A (fr) 1966-10-07
NL6501578A (da) 1965-08-12
ES309167A2 (es) 1965-10-01
DE1545934A1 (de) 1970-10-22
GB1077358A (en) 1967-07-26
US3299053A (en) 1967-01-17
FR4609M (da) 1966-11-21
FR4123M (da) 1966-04-25
DK107032C (da) 1967-04-17
IL22935A (en) 1969-11-30
ES309170A1 (es) 1965-07-16
DE1545936A1 (de) 1969-12-18
IL22869A (en) 1968-11-27
NO119798B (da) 1970-07-06
BE659442A (da) 1965-08-09
CH458372A (de) 1968-06-30
BR6567054D0 (pt) 1973-08-14
FR1443116A (fr) 1966-06-24
IL22902A (en) 1969-01-29
BE659443A (da) 1965-08-09
ES309168A1 (es) 1965-10-01
NO117367B (da) 1969-08-04
NL6501631A (da) 1965-08-12
FR4138M (da) 1966-05-02
BE659444A (da) 1965-08-09
NL141781B (nl) 1974-04-16
BR6567053D0 (pt) 1973-12-26
DK118249B (da) 1970-07-27
DE1545936B2 (de) 1975-09-18
NL6501632A (da) 1965-08-12
GB1051795A (da)
SE307953B (da) 1969-01-27
FR4772M (da) 1967-01-23
BR6567051D0 (pt) 1973-08-14
SE307952B (da) 1969-01-27
SE309597B (da) 1969-03-31
GB1098242A (en) 1968-01-10
BE659445A (da) 1965-08-09
CH467787A (de) 1969-01-31
GB1052144A (da)
CH460030A (de) 1968-07-31
CH460793A (de) 1968-08-15
NO118273B (da) 1969-12-08
ES309169A1 (es) 1965-10-16
BR6567055D0 (pt) 1973-08-02
NL6501579A (da) 1965-08-12
DE1545933A1 (de) 1969-12-18
IL22903A (en) 1969-03-27
DE1545935A1 (de) 1969-12-11
SE321477B (da) 1970-03-09

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