DK1169117T4 - Fremgangsmåde til fremstilling af partikler ved anvendelse af en superkritisk fluid - Google Patents

Fremgangsmåde til fremstilling af partikler ved anvendelse af en superkritisk fluid

Info

Publication number
DK1169117T4
DK1169117T4 DK99962400T DK99962400T DK1169117T4 DK 1169117 T4 DK1169117 T4 DK 1169117T4 DK 99962400 T DK99962400 T DK 99962400T DK 99962400 T DK99962400 T DK 99962400T DK 1169117 T4 DK1169117 T4 DK 1169117T4
Authority
DK
Denmark
Prior art keywords
substance
supercritical fluid
compressible fluid
antisolvent
stream
Prior art date
Application number
DK99962400T
Other languages
English (en)
Other versions
DK1169117T3 (da
Inventor
John Peter Warr
Andrew Robert Souter
Petrus Paulus Cornelis Avontuur
David Roy Merrified
Christopher Edmund Valder
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10844704&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1169117(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of DK1169117T3 publication Critical patent/DK1169117T3/da
Publication of DK1169117T4 publication Critical patent/DK1169117T4/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
DK99962400T 1998-12-21 1999-12-21 Fremgangsmåde til fremstilling af partikler ved anvendelse af en superkritisk fluid DK1169117T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9828204.9A GB9828204D0 (en) 1998-12-21 1998-12-21 Process
PCT/GB1999/004355 WO2000037169A1 (en) 1998-12-21 1999-12-21 Process and apparatus for producing particles using a supercritical fluid

Publications (2)

Publication Number Publication Date
DK1169117T3 DK1169117T3 (da) 2006-02-20
DK1169117T4 true DK1169117T4 (da) 2009-06-15

Family

ID=10844704

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99962400T DK1169117T4 (da) 1998-12-21 1999-12-21 Fremgangsmåde til fremstilling af partikler ved anvendelse af en superkritisk fluid

Country Status (11)

Country Link
US (1) US6830714B1 (da)
EP (1) EP1169117B2 (da)
JP (1) JP4718011B2 (da)
AT (1) ATE306314T1 (da)
AU (1) AU1876100A (da)
CY (1) CY1105172T1 (da)
DE (1) DE69932948T3 (da)
DK (1) DK1169117T4 (da)
ES (1) ES2251250T5 (da)
GB (1) GB9828204D0 (da)
WO (1) WO2000037169A1 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4874483B2 (ja) * 1999-06-09 2012-02-15 ロバート イー． シーバース 超臨界流体補助ネブライゼーション及びバブル乾燥
GB9920148D0 (en) * 1999-08-25 1999-10-27 Smithkline Beecham Plc Novel composition
CH694686A5 (it) * 2000-03-04 2005-06-15 Eco2 Sa Prodotto di micronizzazione di sostanze farmaceutiche.
AU2002221320B2 (en) * 2000-12-08 2006-06-15 The University Of Sydney Synthesis of small particles
GB0102075D0 (en) 2001-01-26 2001-03-14 Astrazeneca Ab Process
SI1363726T1 (en) 2001-02-26 2005-02-28 Dompe S.P.A. Apparatus and method for micron and submicron particle formation
DE10109829A1 (de) * 2001-03-01 2002-09-05 Celanese Ventures Gmbh Polymermembran, Verfahren zu deren Herstellung sowie deren Verwendung
US6869551B2 (en) 2001-03-30 2005-03-22 Picoliter Inc. Precipitation of solid particles from droplets formed using focused acoustic energy
US6610223B2 (en) 2001-03-30 2003-08-26 Picoliter Inc. Focused acoustic energy in the generation of solid particles
US6596206B2 (en) 2001-03-30 2003-07-22 Picoliter Inc. Generation of pharmaceutical agent particles using focused acoustic energy
EP1401563B2 (en) * 2001-07-02 2015-09-16 Micro & Nano Materials SAGL Process for the production of micro and/or nano particles
AU2002365617B2 (en) * 2001-12-07 2008-04-03 Map Pharmaceuticals, Inc. Synthesis of small particles
CA2466525C (en) 2001-12-07 2011-05-17 Eiffel Technologies Limited Synthesis of small particles
KR20100112206A (ko) * 2002-04-11 2010-10-18 메디뮨 엘엘씨 분무 건조에 의한 생물학적 활성 물질의 보존
WO2003086606A1 (en) * 2002-04-12 2003-10-23 Feyecon Development & Implementation B.V. Process for small particle formation
DE10248619A1 (de) * 2002-10-18 2004-04-29 Bayer Ag Verfahren zur Herstellung pulverförmiger Wirkstoff-Formulierungen mit kompressiblen Fluiden
JP2004148174A (ja) * 2002-10-29 2004-05-27 Kobe Steel Ltd 超臨界流体を利用して微粒子を製造する方法および装置
JP3663408B2 (ja) * 2003-06-30 2005-06-22 株式会社アイテック 高温高圧水を用いる微粒子製造方法および微粒子製造装置
KR100603974B1 (ko) 2003-12-05 2006-07-25 김갑식 고체상 지질을 용매로 이용한 나노수준의 또는 비결정질입자의 제조 방법
JPWO2005073285A1 (ja) * 2004-01-28 2007-09-13 独立行政法人科学技術振興機構 超臨界流体からの貧溶媒中への急速膨張法を用いた微粒子製造法
WO2007009164A1 (en) 2005-07-15 2007-01-25 Eiffel Technologies Limited Method of particle formation
EP2164647B1 (en) 2007-06-29 2013-11-06 Cellutech AB Method to prepare superhydrophobic surfaces on solid bodies by rapid expansion solutions
AU2008331967B2 (en) * 2007-12-07 2012-10-25 Xspray Microparticles Ab Method and arrangement for the production of particles
US20100294986A1 (en) * 2009-05-19 2010-11-25 Massachusetts Institute Of Technology Supercritical fluid facilitated particle formation in microfluidic systems
US20100298602A1 (en) * 2009-05-19 2010-11-25 Massachusetts Institute Of Technology Systems and methods for microfluidic crystallization
GB0915106D0 (en) 2009-08-28 2009-10-07 Glaxo Group Ltd Process
CA2793241C (en) 2010-03-22 2020-07-14 Bio-Synectics Inc. Method for preparing nano-particles
US9138705B2 (en) 2010-11-22 2015-09-22 Hong Kong Polytechnic University Method for precipitating a solute from a solution
DE102011105201A1 (de) * 2011-04-11 2012-10-11 Martin Ruda Luftkappe, Anordnung aus Haltering und Luftkappe und Farbleiteinrich-tung für eine Farbspritzpistole
US20150024209A1 (en) * 2012-03-12 2015-01-22 Sharp Kabushiki Kaisha Modified particle purification method and manufacturing method, modified particles, functional material, optical member, heat transfer member, and coverage rate analysis device and coverage rate analysis method
US10239009B2 (en) 2013-03-14 2019-03-26 Lawrence Livermore National Security, Llc Continuously-operable flow stream processing system and method
US8778181B1 (en) 2013-03-14 2014-07-15 Crititech, Inc. Equipment assembly for and method of processing particles
US20170050337A1 (en) * 2013-05-02 2017-02-23 Melior Innovations, Inc. Formation apparatus, systems and methods for manufacturing polymer derived ceramic structures
JP6429949B2 (ja) * 2017-01-26 2018-11-28 タナベウィルテック株式会社 微粒子製造装置および微粒子製造方法
CN109152745A (zh) 2017-04-21 2019-01-04 株式会社生物研究 利用脂质作为研磨工序中的润滑剂的制备活性物质纳米粒子的方法
CN112007584A (zh) * 2020-08-31 2020-12-01 胡勇刚 一种油脂的超临界颗粒制备工艺

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Publication number Priority date Publication date Assignee Title
US5639441A (en) † 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation
GB9313642D0 (en) † 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
GB9413202D0 (en) * 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
AU709384B2 (en) * 1996-03-01 1999-08-26 University Of Kansas, The Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents
GB9622173D0 (en) * 1996-10-24 1996-12-18 Glaxo Group Ltd Particulate Products
GB9703673D0 (en) † 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles

Also Published As

Publication number Publication date
AU1876100A (en) 2000-07-12
GB9828204D0 (en) 1999-02-17
EP1169117B1 (en) 2005-10-12
US6830714B1 (en) 2004-12-14
EP1169117A1 (en) 2002-01-09
DE69932948D1 (de) 2006-10-05
ATE306314T1 (de) 2005-10-15
DE69932948T3 (de) 2009-08-13
ES2251250T5 (es) 2009-07-06
JP4718011B2 (ja) 2011-07-06
JP2002532244A (ja) 2002-10-02
ES2251250T3 (es) 2006-04-16
DK1169117T3 (da) 2006-02-20
WO2000037169A1 (en) 2000-06-29
EP1169117B2 (en) 2009-03-18
CY1105172T1 (el) 2010-03-03
DE69932948T2 (de) 2007-01-11

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