NO20054908L - Fremgangsmate for findeling og stabilisering av sma partikler i suspensjon - Google Patents
Fremgangsmate for findeling og stabilisering av sma partikler i suspensjonInfo
- Publication number
- NO20054908L NO20054908L NO20054908A NO20054908A NO20054908L NO 20054908 L NO20054908 L NO 20054908L NO 20054908 A NO20054908 A NO 20054908A NO 20054908 A NO20054908 A NO 20054908A NO 20054908 L NO20054908 L NO 20054908L
- Authority
- NO
- Norway
- Prior art keywords
- suspension
- small particles
- comminuting
- liquid stream
- stabilizing small
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
- Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
- Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system
- Y10S516/925—Phase inversion
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/84—Manufacture, treatment, or detection of nanostructure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Colloid Chemistry (AREA)
Abstract
Fremgangsmåte og apparatur for finoppdeling og stabilisering av små partikler. I en apparatur ifølge en utførelsesform blir en organisk forbindelse oppløst i et løsningsmiddel slik at det dannes en partikkelsuspensjon beveget som en første væskestrøm, og suspensjonen beveges som en andre væskestrøm, hvor den andre væskestrøm er orientert og posisjonert med hensyn til den første strøm slik at det medfører skjærvirkning mellom strømmene og blanding av minst noen av partiklene i den første og andre strøm.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45742403P | 2003-03-24 | 2003-03-24 | |
US10/806,050 US7511079B2 (en) | 2003-03-24 | 2004-03-22 | Methods and apparatuses for the comminution and stabilization of small particles |
PCT/US2004/009242 WO2004084860A2 (en) | 2003-03-24 | 2004-03-24 | Methods for the comminution and stabilization of small particles in suspension |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20054908D0 NO20054908D0 (no) | 2005-10-24 |
NO20054908L true NO20054908L (no) | 2005-12-21 |
Family
ID=33101285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20054908A NO20054908L (no) | 2003-03-24 | 2005-10-24 | Fremgangsmate for findeling og stabilisering av sma partikler i suspensjon |
Country Status (10)
Country | Link |
---|---|
US (1) | US7511079B2 (no) |
EP (1) | EP1605915A2 (no) |
JP (1) | JP2006521396A (no) |
KR (1) | KR20050115298A (no) |
AU (1) | AU2004224307A1 (no) |
BR (1) | BRPI0408707A (no) |
CA (1) | CA2519536A1 (no) |
MX (1) | MXPA05010045A (no) |
NO (1) | NO20054908L (no) |
WO (1) | WO2004084860A2 (no) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1556018A1 (en) * | 2002-09-30 | 2005-07-27 | Acusphere, Inc. | Sustained release porous microparticles for inhalation |
US20040121003A1 (en) * | 2002-12-19 | 2004-06-24 | Acusphere, Inc. | Methods for making pharmaceutical formulations comprising deagglomerated microparticles |
US6962006B2 (en) * | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
US7511079B2 (en) | 2003-03-24 | 2009-03-31 | Baxter International Inc. | Methods and apparatuses for the comminution and stabilization of small particles |
JP2007533634A (ja) * | 2003-09-30 | 2007-11-22 | アキュスフィア, インコーポレイテッド | 注射、経口、または局所用の徐放性医薬製剤 |
ES2338039T3 (es) * | 2005-04-13 | 2010-05-03 | ABBOTT GMBH & CO. KG | Procedimiento para la obtencion cuidadosa de supensiones de particulas de elevada finura y particulas de elevada finura, asi como su aplicacion. |
DE102005053862A1 (de) * | 2005-11-04 | 2007-05-10 | Pharmasol Gmbh | Verfahren und Vorrichtung zur Herstellung hochfeiner Partikel sowie zur Beschichtung solcher Partikel |
US7913223B2 (en) * | 2005-12-16 | 2011-03-22 | Dialogic Corporation | Method and system for development and use of a user-interface for operations, administration, maintenance and provisioning of a telecommunications system |
US8946200B2 (en) * | 2006-11-02 | 2015-02-03 | Southwest Research Institute | Pharmaceutically active nanosuspensions |
US8282266B2 (en) * | 2007-06-27 | 2012-10-09 | H R D Corporation | System and process for inhibitor injection |
US20090187135A1 (en) * | 2008-01-18 | 2009-07-23 | Eilaz Babaev | Ultrasonic syringe |
US8404850B2 (en) * | 2008-03-13 | 2013-03-26 | Southwest Research Institute | Bis-quaternary pyridinium-aldoxime salts and treatment of exposure to cholinesterase inhibitors |
US8187554B2 (en) | 2008-04-23 | 2012-05-29 | Microfluidics International Corporation | Apparatus and methods for nanoparticle generation and process intensification of transport and reaction systems |
US8722706B2 (en) * | 2008-08-15 | 2014-05-13 | Southwest Research Institute | Two phase bioactive formulations of bis-quaternary pyridinium oxime sulfonate salts |
US8309134B2 (en) * | 2008-10-03 | 2012-11-13 | Southwest Research Institute | Modified calcium phosphate nanoparticle formation |
US9028873B2 (en) * | 2010-02-08 | 2015-05-12 | Southwest Research Institute | Nanoparticles for drug delivery to the central nervous system |
US10350556B2 (en) | 2011-01-07 | 2019-07-16 | Microfluidics International Corporation | Low holdup volume mixing chamber |
US9079140B2 (en) | 2011-04-13 | 2015-07-14 | Microfluidics International Corporation | Compact interaction chamber with multiple cross micro impinging jets |
US9199209B2 (en) | 2011-04-13 | 2015-12-01 | Microfluidics International Corporation | Interaction chamber with flow inlet optimization |
EP2934484A1 (en) * | 2012-12-19 | 2015-10-28 | Kashiv Pharma, LLC | Supersaturated stabilized nanoparticles for poorly soluble drugs |
JP6462403B2 (ja) * | 2015-02-23 | 2019-01-30 | 大川原化工機株式会社 | 湿式分散器 |
CA3075827C (en) | 2018-06-22 | 2021-11-16 | Delphi Scientific, Llc | Apparatus, systems, and methods for continuous manufacturing of nanomaterials and high purity chemicals |
WO2020041631A1 (en) * | 2018-08-22 | 2020-02-27 | Avalyn Pharma Inc. | Specially formulated compositions of inhaled nintedanib and nintedanib salts |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
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US3685261A (en) * | 1971-02-16 | 1972-08-22 | Environeering | Wet scrubber for contaminated gas |
US4908154A (en) * | 1981-04-17 | 1990-03-13 | Biotechnology Development Corporation | Method of forming a microemulsion |
CA1282405C (en) | 1984-05-21 | 1991-04-02 | Michael R. Violante | Method for making uniformly sized particles from water-insoluble organic compounds |
IE67187B1 (en) * | 1990-06-15 | 1996-03-06 | Merck & Co Inc | A crystallization method to improve crystal structure and size |
DE4241549A1 (de) * | 1992-12-10 | 1994-06-16 | Nied Roland | Verfahren und Vorrichtung für die Prallzerkleinerung von Feststoffpartikeln |
JPH07328471A (ja) * | 1994-06-06 | 1995-12-19 | Furukawa Co Ltd | 粉砕装置 |
US5720551A (en) * | 1994-10-28 | 1998-02-24 | Shechter; Tal | Forming emulsions |
SE9403846D0 (sv) * | 1994-11-09 | 1994-11-09 | Univ Ohio State Res Found | Small particle formation |
DE4440337A1 (de) * | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
SE9501384D0 (sv) * | 1995-04-13 | 1995-04-13 | Astra Ab | Process for the preparation of respirable particles |
US5833891A (en) * | 1996-10-09 | 1998-11-10 | The University Of Kansas | Methods for a particle precipitation and coating using near-critical and supercritical antisolvents |
JPH10137618A (ja) * | 1996-11-14 | 1998-05-26 | Ritsumeikan | 微細粒子製造方法 |
DE69813254T2 (de) * | 1997-08-05 | 2004-04-01 | Microfluidics International Corp., Newton | Hochdruck mischer-reaktor mit mehrfachströmen |
EP1293259A3 (en) | 1997-12-17 | 2004-01-07 | Universidad De Sevilla | Device and method for creating aerosols for drug delivery |
US6086376A (en) * | 1998-01-30 | 2000-07-11 | Rtp Pharma Inc. | Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant |
JP2934229B1 (ja) * | 1998-05-14 | 1999-08-16 | 清二 加川 | 固液混合流体の破砕・分散装置 |
US8293277B2 (en) * | 1998-10-01 | 2012-10-23 | Alkermes Pharma Ireland Limited | Controlled-release nanoparticulate compositions |
US6610317B2 (en) * | 1999-05-27 | 2003-08-26 | Acusphere, Inc. | Porous paclitaxel matrices and methods of manufacture thereof |
DE10007816A1 (de) | 2000-02-21 | 2001-09-06 | Bayer Ag | Verfahren zur Herstellung von Nanosuspensionen |
EP1276465B1 (en) * | 2000-04-20 | 2014-03-12 | Jagotec AG | Improved water-insoluble drug particle process |
KR100867392B1 (ko) * | 2000-08-15 | 2008-11-06 | 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 | 마이크로입자 |
US6977085B2 (en) * | 2000-12-22 | 2005-12-20 | Baxter International Inc. | Method for preparing submicron suspensions with polymorph control |
EP1642571A3 (en) * | 2000-12-22 | 2007-06-27 | Baxter International Inc. | Method for preparing submicron particle suspensions |
US6884436B2 (en) * | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
US7037528B2 (en) * | 2000-12-22 | 2006-05-02 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
JP2003001079A (ja) * | 2001-06-18 | 2003-01-07 | Karasawa Fine Ltd | 粒子微細化装置 |
US7511079B2 (en) | 2003-03-24 | 2009-03-31 | Baxter International Inc. | Methods and apparatuses for the comminution and stabilization of small particles |
-
2004
- 2004-03-22 US US10/806,050 patent/US7511079B2/en not_active Expired - Fee Related
- 2004-03-24 AU AU2004224307A patent/AU2004224307A1/en not_active Abandoned
- 2004-03-24 BR BRPI0408707-0A patent/BRPI0408707A/pt not_active IP Right Cessation
- 2004-03-24 MX MXPA05010045A patent/MXPA05010045A/es unknown
- 2004-03-24 JP JP2006509324A patent/JP2006521396A/ja active Pending
- 2004-03-24 CA CA002519536A patent/CA2519536A1/en not_active Abandoned
- 2004-03-24 KR KR1020057017803A patent/KR20050115298A/ko not_active Application Discontinuation
- 2004-03-24 EP EP04758149A patent/EP1605915A2/en not_active Withdrawn
- 2004-03-24 WO PCT/US2004/009242 patent/WO2004084860A2/en active Application Filing
-
2005
- 2005-10-24 NO NO20054908A patent/NO20054908L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR20050115298A (ko) | 2005-12-07 |
AU2004224307A1 (en) | 2004-10-07 |
NO20054908D0 (no) | 2005-10-24 |
US7511079B2 (en) | 2009-03-31 |
CA2519536A1 (en) | 2004-10-07 |
WO2004084860A2 (en) | 2004-10-07 |
MXPA05010045A (es) | 2005-10-26 |
JP2006521396A (ja) | 2006-09-21 |
US20040266890A1 (en) | 2004-12-30 |
BRPI0408707A (pt) | 2006-03-07 |
WO2004084860A3 (en) | 2005-03-24 |
EP1605915A2 (en) | 2005-12-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |