DK1116719T3 - 3-(1-hydroxy-pentyliden)-5-nitro-3H-benzofuran-2-on, fremgangsmåde til fremstilling deraf og anvendelse deraf - Google Patents

3-(1-hydroxy-pentyliden)-5-nitro-3H-benzofuran-2-on, fremgangsmåde til fremstilling deraf og anvendelse deraf

Info

Publication number
DK1116719T3
DK1116719T3 DK01810033T DK01810033T DK1116719T3 DK 1116719 T3 DK1116719 T3 DK 1116719T3 DK 01810033 T DK01810033 T DK 01810033T DK 01810033 T DK01810033 T DK 01810033T DK 1116719 T3 DK1116719 T3 DK 1116719T3
Authority
DK
Denmark
Prior art keywords
preparation
pentylidene
benzofuran
nitro
hydroxy
Prior art date
Application number
DK01810033T
Other languages
Danish (da)
English (en)
Inventor
Alain Schouteeten
Francoise Mordacq
Original Assignee
Clariant France Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clariant France Sa filed Critical Clariant France Sa
Application granted granted Critical
Publication of DK1116719T3 publication Critical patent/DK1116719T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK01810033T 2000-01-17 2001-01-15 3-(1-hydroxy-pentyliden)-5-nitro-3H-benzofuran-2-on, fremgangsmåde til fremstilling deraf og anvendelse deraf DK1116719T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0000523A FR2803846B1 (fr) 2000-01-17 2000-01-17 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation
EP01810033A EP1116719B1 (en) 2000-01-17 2001-01-15 3-(1-Hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-one, a process for the preparation thereof and the use thereof

Publications (1)

Publication Number Publication Date
DK1116719T3 true DK1116719T3 (da) 2005-07-18

Family

ID=8845968

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01810033T DK1116719T3 (da) 2000-01-17 2001-01-15 3-(1-hydroxy-pentyliden)-5-nitro-3H-benzofuran-2-on, fremgangsmåde til fremstilling deraf og anvendelse deraf

Country Status (13)

Country Link
US (2) US6515147B2 (zh)
EP (1) EP1116719B1 (zh)
JP (1) JP4408578B2 (zh)
KR (1) KR100788529B1 (zh)
CN (1) CN1204133C (zh)
AT (1) ATE292630T1 (zh)
DE (1) DE60109829T2 (zh)
DK (1) DK1116719T3 (zh)
ES (1) ES2238408T3 (zh)
FR (1) FR2803846B1 (zh)
HU (1) HUP0100146A3 (zh)
NO (1) NO327039B1 (zh)
TW (1) TW564246B (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10237819A1 (de) * 2002-08-19 2004-03-04 Bayer Ag 5-Nitrobenzofurane
FR2864536B1 (fr) * 2003-12-24 2006-03-17 Clariant France Sa Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
GB0719180D0 (en) * 2007-10-02 2007-11-14 Cambrex Karlskoga Ab New process
CN102065855A (zh) * 2008-04-17 2011-05-18 赛诺菲-安万特 决奈达隆在制备用于预防因心血管疾病住院或死亡的药物中的用途
FR2930149B1 (fr) * 2008-04-17 2011-02-18 Sanofi Aventis Association de dronedarone avec au moins un diuretique, son application en therapeutique
EP2116239A1 (en) * 2008-04-29 2009-11-11 Sanofi-Aventis Method for managing the risks associated with an increase in serum creatinine during dronedarone treatment
EP2246341A1 (en) 2009-01-23 2010-11-03 Lonza Ltd. Process for preparing 2-Alkyl-3-aroyl-5-nitro-benzofurans
CN102276561A (zh) * 2010-06-09 2011-12-14 江苏恒瑞医药股份有限公司 决奈达隆及其盐的制备方法
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3248401A (en) * 1966-04-26 Diethylaminoe hoxybenzoyl benzofurans
US4252817A (en) * 1975-03-12 1981-02-24 Sandoz Ltd. Substituted-2,3-dihydrobenzofuran-2-ones
FR2642755B1 (zh) * 1989-02-07 1993-11-05 Sanofi
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
GB9416219D0 (en) * 1994-08-11 1994-10-05 Karobio Ab Receptor ligands

Also Published As

Publication number Publication date
DE60109829T2 (de) 2006-01-19
JP4408578B2 (ja) 2010-02-03
EP1116719B1 (en) 2005-04-06
NO327039B1 (no) 2009-04-06
DE60109829D1 (de) 2005-05-12
FR2803846A1 (fr) 2001-07-20
NO20010265L (no) 2001-07-18
CN1306000A (zh) 2001-08-01
KR20010076278A (ko) 2001-08-11
ES2238408T3 (es) 2005-09-01
EP1116719A2 (en) 2001-07-18
NO20010265D0 (no) 2001-01-16
CN1204133C (zh) 2005-06-01
FR2803846B1 (fr) 2002-04-05
HU0100146D0 (en) 2001-03-28
HUP0100146A2 (hu) 2002-01-28
HUP0100146A3 (en) 2003-07-28
EP1116719A3 (en) 2001-10-24
JP2001233870A (ja) 2001-08-28
US20010012900A1 (en) 2001-08-09
KR100788529B1 (ko) 2007-12-24
US6515147B2 (en) 2003-02-04
ATE292630T1 (de) 2005-04-15
TW564246B (en) 2003-12-01
USRE39755E1 (en) 2007-07-31

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