DE60109829D1 - 3-(1-Hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-on, ein Verfahren zu seiner Herstellung und seine Verwendung - Google Patents

3-(1-Hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-on, ein Verfahren zu seiner Herstellung und seine Verwendung

Info

Publication number
DE60109829D1
DE60109829D1 DE60109829T DE60109829T DE60109829D1 DE 60109829 D1 DE60109829 D1 DE 60109829D1 DE 60109829 T DE60109829 T DE 60109829T DE 60109829 T DE60109829 T DE 60109829T DE 60109829 D1 DE60109829 D1 DE 60109829D1
Authority
DE
Germany
Prior art keywords
preparation
benzofuran
nitro
hydroxy
pentylidenes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60109829T
Other languages
English (en)
Other versions
DE60109829T2 (de
Inventor
Alain Schouteeten
Francoise Mordacq
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clariant France SA
Original Assignee
Clariant France SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clariant France SA filed Critical Clariant France SA
Publication of DE60109829D1 publication Critical patent/DE60109829D1/de
Application granted granted Critical
Publication of DE60109829T2 publication Critical patent/DE60109829T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60109829T 2000-01-17 2001-01-15 3-(1-Hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-on, ein Verfahren zu seiner Herstellung und seine Verwendung Expired - Lifetime DE60109829T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0000523 2000-01-17
FR0000523A FR2803846B1 (fr) 2000-01-17 2000-01-17 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation

Publications (2)

Publication Number Publication Date
DE60109829D1 true DE60109829D1 (de) 2005-05-12
DE60109829T2 DE60109829T2 (de) 2006-01-19

Family

ID=8845968

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60109829T Expired - Lifetime DE60109829T2 (de) 2000-01-17 2001-01-15 3-(1-Hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-on, ein Verfahren zu seiner Herstellung und seine Verwendung

Country Status (13)

Country Link
US (2) US6515147B2 (de)
EP (1) EP1116719B1 (de)
JP (1) JP4408578B2 (de)
KR (1) KR100788529B1 (de)
CN (1) CN1204133C (de)
AT (1) ATE292630T1 (de)
DE (1) DE60109829T2 (de)
DK (1) DK1116719T3 (de)
ES (1) ES2238408T3 (de)
FR (1) FR2803846B1 (de)
HU (1) HUP0100146A3 (de)
NO (1) NO327039B1 (de)
TW (1) TW564246B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10237819A1 (de) * 2002-08-19 2004-03-04 Bayer Ag 5-Nitrobenzofurane
FR2864536B1 (fr) 2003-12-24 2006-03-17 Clariant France Sa Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
GB0719180D0 (en) 2007-10-02 2007-11-14 Cambrex Karlskoga Ab New process
AR072950A1 (es) 2008-04-17 2010-10-06 Sanofi Aventis Uso de dronedarona para la preparacion de un medicamento para uso en la prevencion de la hospitalizacion cardiovascular o de la mortalidad, composicion farmaceutica, articulo de fabricacion y envase
FR2930149B1 (fr) * 2008-04-17 2011-02-18 Sanofi Aventis Association de dronedarone avec au moins un diuretique, son application en therapeutique
EP2116239A1 (de) * 2008-04-29 2009-11-11 Sanofi-Aventis Verfahren zur Verwaltung von Risiken in Zusammenhang mit der Zunahme von Serumkreatinin bei der Dronedaron-Behandlung
EP2246341A1 (de) 2009-01-23 2010-11-03 Lonza Ltd. Verfahren zur Herstellung von 2-Alkyl-3-aroyl-5-nitro-benzofuranen
CN102276561A (zh) * 2010-06-09 2011-12-14 江苏恒瑞医药股份有限公司 决奈达隆及其盐的制备方法
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3248401A (en) * 1966-04-26 Diethylaminoe hoxybenzoyl benzofurans
US4252817A (en) * 1975-03-12 1981-02-24 Sandoz Ltd. Substituted-2,3-dihydrobenzofuran-2-ones
FR2642755B1 (de) * 1989-02-07 1993-11-05 Sanofi
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
GB9416219D0 (en) * 1994-08-11 1994-10-05 Karobio Ab Receptor ligands

Also Published As

Publication number Publication date
KR100788529B1 (ko) 2007-12-24
HUP0100146A3 (en) 2003-07-28
EP1116719A2 (de) 2001-07-18
FR2803846A1 (fr) 2001-07-20
CN1204133C (zh) 2005-06-01
DK1116719T3 (da) 2005-07-18
TW564246B (en) 2003-12-01
JP4408578B2 (ja) 2010-02-03
EP1116719A3 (de) 2001-10-24
HUP0100146A2 (hu) 2002-01-28
US6515147B2 (en) 2003-02-04
KR20010076278A (ko) 2001-08-11
ES2238408T3 (es) 2005-09-01
JP2001233870A (ja) 2001-08-28
ATE292630T1 (de) 2005-04-15
USRE39755E1 (en) 2007-07-31
NO20010265L (no) 2001-07-18
US20010012900A1 (en) 2001-08-09
HU0100146D0 (en) 2001-03-28
FR2803846B1 (fr) 2002-04-05
CN1306000A (zh) 2001-08-01
NO20010265D0 (no) 2001-01-16
NO327039B1 (no) 2009-04-06
EP1116719B1 (de) 2005-04-06
DE60109829T2 (de) 2006-01-19

Similar Documents

Publication Publication Date Title
DE60109829D1 (de) 3-(1-Hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-on, ein Verfahren zu seiner Herstellung und seine Verwendung
ES2151850B1 (es) Intermedio para la sintesis de amlodipino para su obtencion y utilizacion correspondiente.
DE60233664D1 (de) Verfahren zur herstellung von pyridinverbindungen
DE59910677D1 (de) Verfahren sowie neue zwischenprodukte zur herstellung von isoxazolin-3-yl-acylbenzolen
ATE255103T1 (de) Verfahren zur herstellung von pyridinmethanol- verbindungen
HUP0202006A2 (hu) Eljárás 2-amino-4-(4-fluorfenil)-6-alkil-pirimidin-5-karboxilát-származékok előállítására
DE69521012D1 (de) Verfahren zur Herstellung von 1-(4,5-Dihydro)2-thiazolyl-3-Azetidinthiolderivaten
ATE167671T1 (de) Beta-aminovinylketone, verfahren zur herstellung und ihre verwendung bei der herstellung von beta- diketonen
ATE337304T1 (de) Neues verfahren zur herstellung einer chinolon- carbonsäure
DK1105392T3 (da) Fremgangsmåde til fremstilling af mellemprodukter for imidazodiazepin
DE60116201D1 (de) Verfahren zur Herstellung von Cephalosporin-Verbindungen und Zwischenprodukte für die Synthese dieser Verbindungen
NO330965B1 (no) Fremgangsmate for fremstilling av substituerte imidazolderivater, mellomprodukter anvendt i fremgangsmaten samt fremgangsmate for fremstilling av mellomprodukt
ATE211136T1 (de) Coumarin-derivate, verfahren zu deren herstellung und deren verwendung
DK0492350T3 (da) Fremgangsmåde til fremstilling af (S)-vinyl- og (S)-allenyl-GABA
WO2004024735A3 (en) A new process for the preparation of epothilone derivatives, new epothilone derivatives as well as new intermediate products for the process and the methods of preparing same
WO2002076940A3 (en) Process for preparing arylpiperidine carbinol intermediates and derivatives
DE60124831D1 (de) Ein verfahren zur herstellung substituierter alkylamin-derivate
DE50107619D1 (de) Verfahren zur herstellung von 4-brom-anilin-derivaten
DE60008561D1 (de) Verfahren zur herstellung von oxazol-derivaten
EP1475369A4 (de) Verfahren zur herstellung einer 3-unsubstituierten-5-amino-4-nitrosopyrazol verbindung, und 2-hydroxylmino-3-oxo propionitril, 3-hydrazono-2-hydroxyimino propionitril verbindung, und verfahren zu deren herstellung
DE60127979D1 (de) Verfahren zur herstellung von 3,5-bisalkylphenolen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DERZEIT KEIN VERTRETER BESTELLT

8328 Change in the person/name/address of the agent

Representative=s name: SPOTT & WEINMILLER, 82008 UNTERHACHING