DK1105728T3 - Modulering af multiple lineage kinase-proteiner - Google Patents
Modulering af multiple lineage kinase-proteinerInfo
- Publication number
- DK1105728T3 DK1105728T3 DK99943759T DK99943759T DK1105728T3 DK 1105728 T3 DK1105728 T3 DK 1105728T3 DK 99943759 T DK99943759 T DK 99943759T DK 99943759 T DK99943759 T DK 99943759T DK 1105728 T3 DK1105728 T3 DK 1105728T3
- Authority
- DK
- Denmark
- Prior art keywords
- lineage kinase
- multiple lineage
- methods
- compound
- protein
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Pain & Pain Management (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Food Science & Technology (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9798098P | 1998-08-26 | 1998-08-26 | |
EP99943759A EP1105728B1 (fr) | 1998-08-26 | 1999-08-18 | Modulation de proteines kinase a lignee multiple |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1105728T3 true DK1105728T3 (da) | 2005-08-08 |
Family
ID=22266038
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99943759T DK1105728T3 (da) | 1998-08-26 | 1999-08-18 | Modulering af multiple lineage kinase-proteiner |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP1105728B1 (fr) |
JP (1) | JP2002523780A (fr) |
KR (1) | KR100700028B1 (fr) |
CN (3) | CN1206535C (fr) |
AT (1) | ATE293254T1 (fr) |
AU (1) | AU765637B2 (fr) |
BG (1) | BG105360A (fr) |
BR (1) | BR9913190A (fr) |
CA (1) | CA2339539A1 (fr) |
CZ (1) | CZ2001701A3 (fr) |
DE (1) | DE69924738T2 (fr) |
DK (1) | DK1105728T3 (fr) |
EA (2) | EA006648B1 (fr) |
ES (1) | ES2241316T3 (fr) |
HK (1) | HK1037722A1 (fr) |
HU (1) | HUP0103079A3 (fr) |
NO (1) | NO20010389L (fr) |
NZ (1) | NZ509612A (fr) |
PL (1) | PL346246A1 (fr) |
PT (1) | PT1105728E (fr) |
SK (1) | SK2542001A3 (fr) |
TR (2) | TR200100589T2 (fr) |
UA (1) | UA74772C2 (fr) |
WO (1) | WO2000013015A1 (fr) |
ZA (1) | ZA200100835B (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6811992B1 (en) | 1998-05-14 | 2004-11-02 | Ya Fang Liu | Method for identifying MLK inhibitors for the treatment of neurological conditions |
US6841567B1 (en) | 1999-02-12 | 2005-01-11 | Cephalon, Inc. | Cyclic substituted fused pyrrolocarbazoles and isoindolones |
US7122679B2 (en) * | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
WO2002014536A2 (fr) * | 2000-08-11 | 2002-02-21 | Cephalon, Inc. | Procedes permettant de moduler des proteines kinase a lignee multiple et de cribler des composes les modulant |
US7018999B2 (en) | 2001-05-16 | 2006-03-28 | Cephalon, Inc. | Methods for the treatment and prevention of pain |
FR2826653B1 (fr) | 2001-06-29 | 2005-10-14 | Servier Lab | Nouveaux derives de pyrido-pyrido-pyrrolo[3,2-g]pyrrolo [3,4-e]-indole et pyrido-pyrrolo[2,3-a]pyrrolo[3,4-c] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP2003052395A (ja) * | 2001-08-09 | 2003-02-25 | Japan Tissue Engineering:Kk | 移植適正判定方法 |
AR069501A1 (es) | 2007-11-30 | 2010-01-27 | Genentech Inc | Anticuerpos anti- vegf (factor de crecimiento endotelial vascular) |
JP2011517339A (ja) * | 2008-02-04 | 2011-06-02 | ガラパゴス・ナムローゼ・フェンノートシャップ | 神経変性疾患の治療に有用な分子標的及び化合物並びにこれらの同定方法 |
US20100056609A1 (en) * | 2008-08-26 | 2010-03-04 | Washington University | Methods and compositions for inhibition of axonal degeneration by modulation of the dlk/jnk pathway |
AU2009308293B2 (en) * | 2008-10-22 | 2015-02-05 | Genentech, Inc. | Modulation of axon degeneration |
AU2015202365B2 (en) * | 2008-10-22 | 2016-11-24 | Genentech, Inc. | Modulation of axon degeneration |
JP2013508401A (ja) * | 2009-10-22 | 2013-03-07 | ジェネンテック, インコーポレイテッド | 軸索変性の調節 |
ES2385157B1 (es) * | 2010-02-25 | 2013-07-08 | Universidad Del País Vasco | Compuestos para el tratamiento de alzheimer. |
WO2013177367A2 (fr) | 2012-05-23 | 2013-11-28 | The Johns Hopkins University | Composés et méthodes d'utilisation de ceux-ci pour traiter des troubles neurodégénératifs |
CN109060472A (zh) * | 2018-07-20 | 2018-12-21 | 上海市农业科学院 | 一种适于荧光染色的草菇菌褶组织切片的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5756494A (en) * | 1992-07-24 | 1998-05-26 | Cephalon, Inc. | Protein kinase inhibitors for treatment of neurological disorders |
US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US5475110A (en) * | 1994-10-14 | 1995-12-12 | Cephalon, Inc. | Fused Pyrrolocarbazoles |
US6811992B1 (en) * | 1998-05-14 | 2004-11-02 | Ya Fang Liu | Method for identifying MLK inhibitors for the treatment of neurological conditions |
-
1999
- 1999-08-18 DK DK99943759T patent/DK1105728T3/da active
- 1999-08-18 CA CA002339539A patent/CA2339539A1/fr not_active Abandoned
- 1999-08-18 UA UA2001031963A patent/UA74772C2/uk unknown
- 1999-08-18 AT AT99943759T patent/ATE293254T1/de active
- 1999-08-18 SK SK254-2001A patent/SK2542001A3/sk unknown
- 1999-08-18 HU HU0103079A patent/HUP0103079A3/hu unknown
- 1999-08-18 JP JP2000567949A patent/JP2002523780A/ja active Pending
- 1999-08-18 BR BR9913190-0A patent/BR9913190A/pt not_active Application Discontinuation
- 1999-08-18 NZ NZ509612A patent/NZ509612A/en not_active IP Right Cessation
- 1999-08-18 CN CNB998101354A patent/CN1206535C/zh not_active Expired - Fee Related
- 1999-08-18 TR TR2001/00589T patent/TR200100589T2/xx unknown
- 1999-08-18 CN CNA200610099703XA patent/CN1879617A/zh active Pending
- 1999-08-18 KR KR1020017002385A patent/KR100700028B1/ko active IP Right Grant
- 1999-08-18 TR TR2004/00635T patent/TR200400635T2/xx unknown
- 1999-08-18 EA EA200100278A patent/EA006648B1/ru not_active IP Right Cessation
- 1999-08-18 ES ES99943759T patent/ES2241316T3/es not_active Expired - Lifetime
- 1999-08-18 EA EA200500934A patent/EA200500934A1/ru unknown
- 1999-08-18 DE DE69924738T patent/DE69924738T2/de not_active Expired - Lifetime
- 1999-08-18 CN CNA2004100491086A patent/CN1589788A/zh active Pending
- 1999-08-18 EP EP99943759A patent/EP1105728B1/fr not_active Expired - Lifetime
- 1999-08-18 AU AU56793/99A patent/AU765637B2/en not_active Ceased
- 1999-08-18 PT PT99943759T patent/PT1105728E/pt unknown
- 1999-08-18 CZ CZ2001701A patent/CZ2001701A3/cs unknown
- 1999-08-18 WO PCT/US1999/018864 patent/WO2000013015A1/fr active IP Right Grant
- 1999-08-18 PL PL99346246A patent/PL346246A1/xx not_active Application Discontinuation
-
2001
- 2001-01-23 NO NO20010389A patent/NO20010389L/no not_active Application Discontinuation
- 2001-01-30 ZA ZA2001/00835A patent/ZA200100835B/en unknown
- 2001-03-19 BG BG105360A patent/BG105360A/bg unknown
- 2001-11-23 HK HK01108292A patent/HK1037722A1/xx not_active IP Right Cessation
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