DK1185279T3 - Midler til behandling af maligne sygdomme ved anvendelse af proteinet YB-1 - Google Patents

Midler til behandling af maligne sygdomme ved anvendelse af proteinet YB-1

Info

Publication number
DK1185279T3
DK1185279T3 DK00949114T DK00949114T DK1185279T3 DK 1185279 T3 DK1185279 T3 DK 1185279T3 DK 00949114 T DK00949114 T DK 00949114T DK 00949114 T DK00949114 T DK 00949114T DK 1185279 T3 DK1185279 T3 DK 1185279T3
Authority
DK
Denmark
Prior art keywords
protein
treatment
agents
malignant diseases
tumour cells
Prior art date
Application number
DK00949114T
Other languages
English (en)
Inventor
Per Sonne Holm
Hans-Dieter Royer
Manfred Dietel
Hermann Lage
Axel Ladhoff
Karsten Juerchott
Stephan Bergmann
Karsten Brand
Original Assignee
Per Sonne Holm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Per Sonne Holm filed Critical Per Sonne Holm
Application granted granted Critical
Publication of DK1185279T3 publication Critical patent/DK1185279T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • A61K35/761Adenovirus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK00949114T 1999-06-21 2000-06-20 Midler til behandling af maligne sygdomme ved anvendelse af proteinet YB-1 DK1185279T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19929569A DE19929569A1 (de) 1999-06-21 1999-06-21 Mittel zur Behandlung maligner Erkrankungen unter Verwendung des Proteins YB-1
PCT/DE2000/001978 WO2000078327A2 (de) 1999-06-21 2000-06-20 Mittel zur behandlung maligner erkrankungen unter verwendung von e1a-defizienten adenoviren mit yb-1 abhängiger replikation

Publications (1)

Publication Number Publication Date
DK1185279T3 true DK1185279T3 (da) 2005-05-23

Family

ID=7912815

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00949114T DK1185279T3 (da) 1999-06-21 2000-06-20 Midler til behandling af maligne sygdomme ved anvendelse af proteinet YB-1

Country Status (8)

Country Link
US (2) US20020086411A1 (da)
EP (1) EP1185279B1 (da)
JP (1) JP2003502378A (da)
AT (1) ATE287722T1 (da)
DE (2) DE19929569A1 (da)
DK (1) DK1185279T3 (da)
ES (1) ES2235917T3 (da)
WO (1) WO2000078327A2 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002044363A1 (en) * 2000-11-28 2002-06-06 Genesis Research And Development Corporation Limited Methods for modulating apoptotic cell death
AU2002230958A1 (en) * 2000-12-18 2002-07-16 Geron Corporation Chimeric cytolytic viruses for cancer treatment
DE50112463D1 (de) * 2000-12-28 2007-06-14 Per Sonne Holm Adenovirale systeme und deren anwendungen
CN1655827B (zh) 2002-05-27 2010-06-23 佩尔·松内·霍尔姆 腺病毒和编码其的核酸的新应用
WO2005051430A1 (de) 2003-11-14 2005-06-09 Per Sonne Holm Neue verwendung von adenoviren und dafür codierenden nukleinsäuren
CA2590257A1 (en) * 2003-11-14 2005-06-09 Per Sonne Holm Novel adenoviruses, nucleic acids that code for the same and the use of said viruses
DE102004060385A1 (de) * 2004-12-14 2006-07-06 Rwth Aachen Verfahren zur Bestimmung entzündlicher Vorgänge und pharmazeutische Zusammensetzungen zur Behandlung derselben
WO2006070023A2 (en) * 2004-12-31 2006-07-06 Per Sonne Holm Method for reversing multiple resistance in animal cells
WO2011071859A1 (en) * 2009-12-08 2011-06-16 Memorial Sloan-Kettering Cancer Center Method and composition to increase radiation-induced tumor therapeutic effects
KR102089121B1 (ko) 2013-03-14 2020-03-13 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 종양살상형 아데노바이러스 조성물
CN108699566B (zh) 2016-02-23 2023-06-30 萨克生物研究学院 对病毒动力学影响最小的治疗性腺病毒中的外源基因表达
CA3013637A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
CA3045892A1 (en) 2016-12-12 2018-06-21 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4947842A (en) * 1988-09-22 1990-08-14 Medical Engineering And Development Institute, Inc. Method and apparatus for treating tissue with first and second modalities
US20020099179A1 (en) * 1989-12-21 2002-07-25 Linda K. Jolliffe Cdr-grafted antibodies
US5846945A (en) * 1993-02-16 1998-12-08 Onyx Pharmaceuticals, Inc. Cytopathic viruses for therapy and prophylaxis of neoplasia
DE69417734T2 (de) * 1993-02-16 1999-10-07 Onyx Pharma Inc Cytopathische viren zur therapie und prophylaxe der neoplasie
US6096718A (en) * 1997-06-05 2000-08-01 Gene Targeting Corp. Tissue specific adenovirus vectors for breast cancer treatment
US20020151461A1 (en) * 1998-02-19 2002-10-17 Hong-Ji Xu Modified retinoblastoma tumor supressor proteins
US6428968B1 (en) * 1999-03-15 2002-08-06 The Trustees Of The University Of Pennsylvania Combined therapy with a chemotherapeutic agent and an oncolytic virus for killing tumor cells in a subject
US6140126A (en) * 1999-10-26 2000-10-31 Isis Pharmaceuticals Inc. Antisense modulation of Y-box binding protein 1 expression
US20030095989A1 (en) * 2000-12-18 2003-05-22 Irving John M. Chimeric cytolytic viruses for cancer treatment
DE10150984A1 (de) * 2001-10-16 2003-04-17 Holm Per Sonne Verwendung des adenoviralen E2-late-Promotors

Also Published As

Publication number Publication date
WO2000078327A2 (de) 2000-12-28
EP1185279A2 (de) 2002-03-13
ATE287722T1 (de) 2005-02-15
DE19929569A1 (de) 2000-12-28
JP2003502378A (ja) 2003-01-21
US20040265277A1 (en) 2004-12-30
US20020086411A1 (en) 2002-07-04
EP1185279B1 (de) 2005-01-26
DE50009365D1 (de) 2005-03-03
ES2235917T3 (es) 2005-07-16
WO2000078327A3 (de) 2001-05-10

Similar Documents

Publication Publication Date Title
TW200607505A (en) Fused heterocyclic kinase inhibitors
PT1206474E (pt) Compostos de sulfonilfenilpirazole uteis como inibidores de cox-2
FR16C0028I2 (fr) Vecteurs viraux et utilisation de ces derniers dans des methodes therapeutiques
DK1185279T3 (da) Midler til behandling af maligne sygdomme ved anvendelse af proteinet YB-1
EP1322307A4 (en) METHODS OF TREATING CELL PROLIFERATION DISORDERS AND VIRAL INFECTIONS
ATE304017T1 (de) Oxazolylpyrazol-derivate als kinase-inhibitoren
BR0114978A (pt) Composições e métodos que são úteis no tratamento de condições ou doenças inflamatórias, metabólicas, e proliferativas celulares
EP1435946B8 (en) Linked biaryl compounds
WO2004050026A3 (en) Compositions and methods for treating prostate cancer
ATE372341T1 (de) Inhibitoren von mitotischem kinesin
NO20052923L (no) Fusjonerte bicykliske nitrogeninneholdende heteroringer
WO2004113571A3 (en) Prostate specific genes and the use thereof as targets for prostate cancer therapy and diagnosis
BRPI0412845A (pt) herpes-vìrus, uso de um vìrus, composição farmacêutica, e, método de tratamento de um tumor em um indivìduo em necessidade do mesmo
DK1742644T3 (da) Terapeutisk sammensætning indeholdende mindst et pyrrolbenzodiazepin-derivat og fludarabin
UA84954C2 (ru) Конденсированные пиримидоны, пригодные для лечения и профилактики злокачественного новообразования
EA200801853A1 (ru) Пептиды, эффективные в лечении опухолей и других заболеваний, требующих удаления или разрушения клеток
DK1755659T3 (da) Anvendelse af anti-alfa5beta1-antistoffer til inhibering af kræftcelleproliferation
EA200400235A1 (ru) Комбинированная терапия для лечения рака
PT1325011E (pt) Metodos e compostos para tratamento de doencas proliferativas
DE60021381D1 (de) Chinonverbindungen zur behandlung von krankheiten
DK1105728T3 (da) Modulering af multiple lineage kinase-proteiner
DK1051187T3 (da) Behandling af follikulære lymfomer ved anvendelse af inhibitorer af lymfotoxin(LT)-syntesevejen
DK1276501T3 (da) Fremgangsmåde til behandling af tumorer under anvendelse af fotodynamisk terapi
DK1162985T3 (da) Matrixproteinsammensætninger til induktion af apoptose
AU3880900A (en) Surface localized colligin/hsp47 in carcinoma cells