DK1105104T3 - Bukkal bioadhæsiv tablet med langvarig frigivelse - Google Patents
Bukkal bioadhæsiv tablet med langvarig frigivelseInfo
- Publication number
- DK1105104T3 DK1105104T3 DK99942454T DK99942454T DK1105104T3 DK 1105104 T3 DK1105104 T3 DK 1105104T3 DK 99942454 T DK99942454 T DK 99942454T DK 99942454 T DK99942454 T DK 99942454T DK 1105104 T3 DK1105104 T3 DK 1105104T3
- Authority
- DK
- Denmark
- Prior art keywords
- long
- term release
- bioadhesive tablet
- buccal bioadhesive
- buccal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9784398P | 1998-08-25 | 1998-08-25 | |
US09/379,310 US6248358B1 (en) | 1998-08-25 | 1999-08-23 | Bioadhesive progressive hydration tablets and methods of making and using the same |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1105104T3 true DK1105104T3 (da) | 2006-02-06 |
Family
ID=22265404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK99942454T DK1105104T3 (da) | 1998-08-25 | 1999-08-24 | Bukkal bioadhæsiv tablet med langvarig frigivelse |
Country Status (26)
Country | Link |
---|---|
US (1) | US6248358B1 (ja) |
EP (1) | EP1105104B1 (ja) |
JP (2) | JP5411398B2 (ja) |
KR (1) | KR100716702B1 (ja) |
CN (2) | CN1259903C (ja) |
AR (1) | AR036972A1 (ja) |
AT (1) | ATE306253T1 (ja) |
AU (1) | AU754880B2 (ja) |
BR (1) | BR9913239B1 (ja) |
CA (1) | CA2341375C (ja) |
DE (1) | DE69927694T2 (ja) |
DK (1) | DK1105104T3 (ja) |
ES (1) | ES2251220T3 (ja) |
HK (1) | HK1034895A1 (ja) |
HU (1) | HU226591B1 (ja) |
IL (1) | IL141445A (ja) |
MA (1) | MA24964A1 (ja) |
MX (1) | MXPA01002007A (ja) |
MY (2) | MY125919A (ja) |
NO (1) | NO331255B1 (ja) |
NZ (1) | NZ509963A (ja) |
PE (1) | PE20001036A1 (ja) |
RU (1) | RU2227022C2 (ja) |
UA (1) | UA78967C2 (ja) |
WO (1) | WO2000010536A1 (ja) |
ZA (1) | ZA995445B (ja) |
Families Citing this family (46)
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US6624200B2 (en) * | 1998-08-25 | 2003-09-23 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
AU2005203703B2 (en) * | 1998-08-25 | 2007-05-24 | Columbia Laboratories (Bermuda) Limited | Bioadhesive progressive hydration tablets |
US7803392B2 (en) | 2000-12-27 | 2010-09-28 | University Of Kentucky Research Foundation | pH-Sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules |
WO2002087552A2 (en) * | 2001-05-01 | 2002-11-07 | Mcgill University | Androgen-mediated neuroprotection and uses thereof |
US7709026B2 (en) | 2001-10-29 | 2010-05-04 | Columbia Laboratories, Inc. | Low concentration of peroxide for treating or preventing vaginal infections |
CN101327326A (zh) * | 2001-10-29 | 2008-12-24 | 哥伦比亚实验室(百慕大群岛)有限公司 | 阴道给药治疗骨盆痛和不孕症的抗节律障碍剂 |
US8425892B2 (en) * | 2001-10-29 | 2013-04-23 | Columbia Laboratories, Inc. | Extended, controlled-release pharmaceutical compositions using charged polymers |
US20030114394A1 (en) * | 2001-10-29 | 2003-06-19 | Levine Howard L. | Vaginally administered anti-dysrhythmic agents for treating pelvic pain |
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SI1617823T1 (sl) * | 2003-01-24 | 2019-07-31 | Nicachet Ab | Vrečka, ki obsega nikotinski sestavek za transmukozno dajanje |
ATE493973T1 (de) | 2004-06-04 | 2011-01-15 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
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KR20070050081A (ko) * | 2004-08-13 | 2007-05-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 프라미펙솔 또는 약제학적으로 허용되는 이의 염을포함하는 연장 방출형 펠렛 제형, 이의 제조방법 및 이의용도 |
US20060286172A1 (en) * | 2005-06-03 | 2006-12-21 | Anu Mahashabde | Pharmaceutical compositions comprising prostanoid-receptor agonists and methods of making and using the same |
US20070048369A1 (en) * | 2005-08-26 | 2007-03-01 | National Starch And Chemical Investment Holding Corporation | Mucosal delivery tablet |
BRPI0619806A2 (pt) | 2005-12-13 | 2011-10-18 | Biodelivery Sciences Int Inc | dispositivo para fornecimento de fármacos transmucosal resistente ao abuso |
WO2007090881A2 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Modified release formulation |
WO2007090883A1 (en) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Extended release formulation |
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EP1837020A1 (en) | 2006-03-24 | 2007-09-26 | Bioalliance Pharma | Mucosal bioadhesive slow release carrier for delivering active principles |
US20070248655A1 (en) * | 2006-04-21 | 2007-10-25 | Haley Jeffrey T | Lenticular shaped protective mouth sore discs |
EP1872775A1 (en) * | 2006-06-29 | 2008-01-02 | Polichem S.A. | Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders |
KR101329496B1 (ko) | 2006-07-21 | 2013-11-13 | 바이오딜리버리 사이언시스 인터내셔널 인코포레이티드 | 향상된 흡수를 갖는 경점막 전달 장치 |
JP5502494B2 (ja) | 2007-01-22 | 2014-05-28 | ターガセプト・インコーポレイテッド | メタニコチンアナログの鼻腔内、バッカル、または舌下投与 |
PT2118123E (pt) | 2007-01-31 | 2016-02-10 | Harvard College | Péptidos de p53 estabilizados e suas utilizações |
US8828981B2 (en) | 2007-02-06 | 2014-09-09 | George Creasy | Progesterone for the treatment or prevention of spontaneous preterm birth |
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EP2163240A1 (en) * | 2008-09-12 | 2010-03-17 | Universita' Degli Studi Di Genova | A method for the production of bioadhesive compact matrices |
KR101792696B1 (ko) | 2009-06-18 | 2017-11-02 | 알레간 인코포레이티드 | 안전한 데스모프레신 투여 |
RU2582678C2 (ru) | 2010-08-13 | 2016-04-27 | Эйлерон Терапьютикс, Инк. | Пептидомиметические макроциклы |
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TWI643868B (zh) | 2011-10-18 | 2018-12-11 | 艾利倫治療公司 | 擬肽巨環化合物 |
US9901539B2 (en) | 2011-12-21 | 2018-02-27 | Biodelivery Sciences International, Inc. | Transmucosal drug delivery devices for use in chronic pain relief |
JP6450191B2 (ja) | 2012-02-15 | 2019-01-09 | エイルロン セラピューティクス,インコーポレイテッド | ペプチドミメティック大環状化合物 |
EP2819688A4 (en) | 2012-02-15 | 2015-10-28 | Aileron Therapeutics Inc | TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES |
WO2014071241A1 (en) | 2012-11-01 | 2014-05-08 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
KR20170058424A (ko) | 2014-09-24 | 2017-05-26 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방 거대고리 및 이의 용도 |
JP2018516844A (ja) | 2015-03-20 | 2018-06-28 | エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. | ペプチド模倣大環状分子およびその使用 |
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-
1999
- 1999-08-23 US US09/379,310 patent/US6248358B1/en not_active Expired - Lifetime
- 1999-08-24 AT AT99942454T patent/ATE306253T1/de active
- 1999-08-24 UA UA2001031967A patent/UA78967C2/uk unknown
- 1999-08-24 RU RU2001107846/15A patent/RU2227022C2/ru not_active IP Right Cessation
- 1999-08-24 EP EP99942454A patent/EP1105104B1/en not_active Expired - Lifetime
- 1999-08-24 AU AU55826/99A patent/AU754880B2/en not_active Ceased
- 1999-08-24 CN CNB998122009A patent/CN1259903C/zh not_active Expired - Fee Related
- 1999-08-24 ES ES99942454T patent/ES2251220T3/es not_active Expired - Lifetime
- 1999-08-24 HU HU0103218A patent/HU226591B1/hu not_active IP Right Cessation
- 1999-08-24 MX MXPA01002007A patent/MXPA01002007A/es not_active IP Right Cessation
- 1999-08-24 CN CNA2005101375941A patent/CN1879608A/zh active Pending
- 1999-08-24 WO PCT/US1999/019260 patent/WO2000010536A1/en active IP Right Grant
- 1999-08-24 JP JP2000565858A patent/JP5411398B2/ja not_active Expired - Fee Related
- 1999-08-24 KR KR1020017002347A patent/KR100716702B1/ko not_active IP Right Cessation
- 1999-08-24 CA CA002341375A patent/CA2341375C/en not_active Expired - Fee Related
- 1999-08-24 DE DE69927694T patent/DE69927694T2/de not_active Expired - Lifetime
- 1999-08-24 IL IL14144599A patent/IL141445A/xx not_active IP Right Cessation
- 1999-08-24 BR BRPI9913239-7A patent/BR9913239B1/pt not_active IP Right Cessation
- 1999-08-24 NZ NZ509963A patent/NZ509963A/en not_active IP Right Cessation
- 1999-08-24 DK DK99942454T patent/DK1105104T3/da active
- 1999-08-25 MY MYPI99003649A patent/MY125919A/en unknown
- 1999-08-25 ZA ZA9905445A patent/ZA995445B/xx unknown
- 1999-08-25 AR ARP990104253A patent/AR036972A1/es active IP Right Grant
- 1999-08-25 MA MA25744A patent/MA24964A1/fr unknown
- 1999-08-25 PE PE1999000855A patent/PE20001036A1/es not_active Application Discontinuation
-
2000
- 2000-06-20 MY MYPI20002772A patent/MY133365A/en unknown
-
2001
- 2001-02-23 NO NO20010919A patent/NO331255B1/no not_active IP Right Cessation
- 2001-07-13 HK HK01104891A patent/HK1034895A1/xx not_active IP Right Cessation
-
2010
- 2010-07-02 JP JP2010151682A patent/JP2010248231A/ja active Pending
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