DK108495C - Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf. - Google Patents
Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf.Info
- Publication number
- DK108495C DK108495C DK626764A DK626764A DK108495C DK 108495 C DK108495 C DK 108495C DK 626764 A DK626764 A DK 626764A DK 626764 A DK626764 A DK 626764A DK 108495 C DK108495 C DK 108495C
- Authority
- DK
- Denmark
- Prior art keywords
- benzomorphans
- substituted
- preparation
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Discharge Lamp (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK108495C true DK108495C (da) | 1967-12-27 |
Family
ID=23297612
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK626764A DK108495C (da) | 1963-12-20 | 1964-12-19 | Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf. |
| DK429865A DK108497C (da) | 1963-12-20 | 1964-12-19 | Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf. |
| DK429765A DK108496C (da) | 1963-12-20 | 1964-12-19 | Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf. |
| DK626864A DK106552C (da) | 1963-12-20 | 1964-12-19 | Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner. |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK429865A DK108497C (da) | 1963-12-20 | 1964-12-19 | Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf. |
| DK429765A DK108496C (da) | 1963-12-20 | 1964-12-19 | Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf. |
| DK626864A DK106552C (da) | 1963-12-20 | 1964-12-19 | Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner. |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT261126B (OSRAM) |
| BE (2) | BE657405A (OSRAM) |
| CH (7) | CH449640A (OSRAM) |
| DE (2) | DE1445854A1 (OSRAM) |
| DK (4) | DK108495C (OSRAM) |
| ES (4) | ES307299A1 (OSRAM) |
| FR (2) | FR4346M (OSRAM) |
| GB (2) | GB1092394A (OSRAM) |
| IL (2) | IL22643A (OSRAM) |
| NL (3) | NL6414820A (OSRAM) |
| NO (2) | NO119274B (OSRAM) |
| SE (2) | SE322779B (OSRAM) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP1506174B1 (en) | 2002-05-17 | 2015-09-30 | Taiwanj Pharmaceuticals Co., Ltd. | Use of naltrexone for treating kidney and liver damage |
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| WO2008106128A2 (en) | 2007-02-26 | 2008-09-04 | Vitae Pharmaceuticals, Inc. | CYCLIC UREA AND CARBAMATE INHIBITORS OF 11β -HYDROXYSTEROID DEHYDROGENASE 1 |
| WO2009017671A1 (en) | 2007-07-26 | 2009-02-05 | Vitae Pharmaceuticals, Inc. | Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 |
| AR069207A1 (es) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
| AR069545A1 (es) | 2007-11-16 | 2010-02-03 | Boehringer Ingelheim Pharma | Derivados de aril y heteroarilcarbonilo de benzomorfanos y estructuras relacionadas, composiciones farmaceuticas que contienen dichos compuestos, obtencion de las mismas, su uso en el tratamiento de enfermedades mediadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa (hsd) 1 y |
| JP5490014B2 (ja) | 2007-12-11 | 2014-05-14 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| JP5490020B2 (ja) | 2008-01-24 | 2014-05-14 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター |
| JP5734666B2 (ja) | 2008-02-11 | 2015-06-17 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の１，３−オキサアゼパン−２−オン及び１，３−ジアゼパン−２−オン阻害剤 |
| EP2245014B1 (en) * | 2008-02-12 | 2011-11-02 | Boehringer Ingelheim International GmbH | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| JP5730021B2 (ja) | 2008-02-15 | 2015-06-03 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤としてのシクロアルキルラクタム誘導体 |
| JP5696037B2 (ja) | 2008-05-01 | 2015-04-08 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター |
| WO2009134384A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2009134387A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| JP5301563B2 (ja) | 2008-05-01 | 2013-09-25 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状インヒビター |
| WO2009138386A2 (en) | 2008-05-13 | 2009-11-19 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| EP2324017B1 (en) | 2008-07-25 | 2014-12-31 | Boehringer Ingelheim International GmbH | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 |
| NZ590495A (en) | 2008-07-25 | 2012-10-26 | Vitae Pharmaceuticals Inc | Dihydropyridin-phenyl-3-oxazinan-2-ones as inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| TW201022266A (en) | 2008-10-23 | 2010-06-16 | Boehringer Ingelheim Int | Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use |
| EP2393807B1 (en) | 2009-02-04 | 2013-08-14 | Boehringer Ingelheim International GmbH | Cyclic inhibitors of 11 -hydroxysteroid dehydrogenase 1 |
| UA109255C2 (ru) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1 |
| EP2438049B1 (en) | 2009-06-02 | 2014-05-14 | Boehringer Ingelheim International GmbH | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
| WO2011002910A1 (en) | 2009-07-01 | 2011-01-06 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| TWI531571B (zh) | 2009-11-06 | 2016-05-01 | 維它藥物公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物 |
| US8933072B2 (en) | 2010-06-16 | 2015-01-13 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| JP5813106B2 (ja) | 2010-06-25 | 2015-11-17 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 代謝障害の処置のための１１−β−ＨＳＤ１のインヒビターとしてのアザスピロヘキサノン |
| KR20130137628A (ko) | 2010-11-02 | 2013-12-17 | 베링거 인겔하임 인터내셔날 게엠베하 | 대사 장애를 치료하기 위한 약제학적 병용물 |
| TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物 |
| US8735585B2 (en) | 2011-08-17 | 2014-05-27 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1618867A patent/CH449640A/de unknown
- 1964-11-30 CH CH1538364A patent/CH448118A/de unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/de unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/de unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/de unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/de unknown
- 1964-11-30 CH CH1538464A patent/CH446371A/de unknown
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/de active Pending
- 1964-12-18 AT AT1074264A patent/AT261126B/de active
- 1964-12-18 IL IL2264364A patent/IL22643A/xx unknown
- 1964-12-18 AT AT392865A patent/AT249276B/de active
- 1964-12-18 AT AT392965A patent/AT249277B/de active
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/de active Pending
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 AT AT1074364A patent/AT253687B/de active
- 1964-12-18 IL IL2264264A patent/IL22642A/xx unknown
- 1964-12-19 DK DK626764A patent/DK108495C/da active
- 1964-12-19 ES ES0307299A patent/ES307299A1/es not_active Expired
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 DK DK429865A patent/DK108497C/da active
- 1964-12-19 ES ES0307301A patent/ES307301A1/es not_active Expired
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-19 DK DK429765A patent/DK108496C/da active
- 1964-12-19 ES ES0307302A patent/ES307302A1/es not_active Expired
- 1964-12-19 DK DK626864A patent/DK106552C/da active
- 1964-12-19 ES ES0307300A patent/ES307300A1/es not_active Expired
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
-
1965
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| DK108497C (da) | 1967-12-27 |
| CH448118A (de) | 1967-12-15 |
| ES307301A1 (es) | 1965-05-16 |
| FR4346M (OSRAM) | 1966-08-16 |
| ES307300A1 (es) | 1965-05-01 |
| AT253687B (de) | 1967-04-25 |
| CH449639A (de) | 1968-01-15 |
| NL127995C (OSRAM) | |
| CH449641A (de) | 1968-01-15 |
| AT261126B (de) | 1968-04-10 |
| DE1445853A1 (de) | 1968-12-05 |
| IL22642A (en) | 1968-07-25 |
| CH449643A (de) | 1968-01-15 |
| CH449640A (de) | 1968-01-15 |
| SE305657B (OSRAM) | 1968-11-04 |
| DE1445854A1 (de) | 1968-12-05 |
| NO119273B (OSRAM) | 1970-04-27 |
| CH446371A (de) | 1967-11-15 |
| SE322779B (OSRAM) | 1970-04-20 |
| DK108496C (da) | 1967-12-27 |
| GB1077711A (en) | 1967-08-02 |
| AT249276B (de) | 1966-09-12 |
| BE657406A (OSRAM) | 1965-06-21 |
| FR4345M (OSRAM) | 1966-08-16 |
| NL6414821A (OSRAM) | 1965-06-21 |
| GB1092394A (en) | 1967-11-22 |
| CH449642A (de) | 1968-01-15 |
| NL6414820A (OSRAM) | 1965-06-21 |
| NO119274B (OSRAM) | 1970-04-27 |
| ES307302A1 (es) | 1965-05-16 |
| IL22643A (en) | 1968-07-25 |
| AT249277B (de) | 1966-09-12 |
| BE657405A (OSRAM) | 1965-06-21 |
| DK106552C (da) | 1967-02-20 |
| ES307299A1 (es) | 1965-05-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK108497C (da) | Fremgangsmåde til fremstilling af substituerede 6,7-benzomorphaner eller syreadditionssalte deraf. | |
| DK108972C (da) | Fremgangsmåde til fremstilling af lipoylpyridoxamin eller syreadditionssalte deraf. | |
| DK125421B (da) | Analogifremgangsmåde til fremstilling af 5-substituerede-aza-dibenzo-cycloheptener eller syreadditionssalte deraf. | |
| DK108169C (da) | Fremgangsmåde til fremstilling af 3-hydroxy-5-aminomethyl-isoxasol eller syreadditionssalte deraf. | |
| DK116000B (da) | Fremgangsmåde til fremstilling af amino-halogen-benzylaminer eller syreadditionssalte heraf. | |
| DK117000B (da) | Fremgangsmåde til fremstilling af substituerede phenylamino-1,3-diazacyclopentener-(2) eller syreadditionssalte heraf. | |
| DK115851B (da) | Fremgangsmåde til fremstilling af 1,2-dihydro-4-aryl-quinazoliner eller syreadditionssalte deraf. | |
| DK112451B (da) | Fremgangsmåde til fremstilling af [1,2-α]-imidazopyridiner eller syreadditionssalte deraf. | |
| DK107942C (da) | Fremgangsmåde til fremstilling af 1,5-disubstituerede 3-aza-1-pentanoler eller syreadditionssalte deraf. | |
| DK108394C (da) | Fremgangsmåde til fremstilling af substituerede imidazo- eller pyrimido-quinazoliner eller syreadditionssalte deraf. | |
| DK125552B (da) | Fremgangsmåde til fremstilling af 1,2,3,4-tetrahydroisoquinolin-2-carboxamidiner eller syreadditionssalte deraf. | |
| DK121604B (da) | Fremgangsmåde til fremstilling af substituerede iminocycloheptatrienderivater eller syreadditionssalte heraf. | |
| DK106381C (da) | Fremgangsmåde til fremstilling af 2-dimethylamino-3,5,6-trimethylpyrazin eller syreadditionssalte heraf. | |
| DK112449B (da) | Fremgangsmåde til fremstilling af 2,3-dihydro-5-pyridyl-1H-1,4-benzodiazepiner eller syreadditionssalte deraf. | |
| DK111893B (da) | Fremgangsmåde til fremstilling af substituerede methylhydraziner eller syreadditionssalte deraf. | |
| DK105649C (da) | Fremgangsmåde til fremstilling af 2-dimethylaminopyrazin eller syreadditionssalte deraf. | |
| DK106380C (da) | Fremgangsmåde til fremstilling af basisk substituerede 11-alkyl-5,6-dihydro-6-oxo-morphanthridiner eller syreadditionssalte deraf. | |
| DK118667B (da) | Fremgangsmåde til fremstilling af 1,3,4,5-tetrahydro-5-phenyl-2H-1,4-benzodiazepin-2-oner eller syreadditionssalte deraf. | |
| DK118345B (da) | Fremgangsmåde til fremstilling af 2,5-diacylamino-3,6-diamino-1,4-dihydroxybenzener eller syreadditionssalte deraf. | |
| DK106144C (da) | Fremgangsmåde til fremstilling af aryl-N-(1,2,5,6-tetrahydro-1,3-dialkyl-4-pyridyl)-alkanoylamider eller syreadditionssalte deraf. | |
| DK107169C (da) | Fremgangsmåde til fremstilling af 10-monoalkylaminoalkyl-10,11-dihydro-11-oxo-5H-dibenzo(b,e)(1,4)diazepiner eller syreadditionssalte deraf. | |
| DK108857C (da) | Fremgangsmåde til fremstilling af phenylcyclohexylalkylaminer eller syreadditionssalte deraf. | |
| DK118241B (da) | Fremgangsmåde til fremstilling af 2-amino-oxazoliner eller syreadditionssalte heraf. | |
| DK112530B (da) | Fremgangsmåde til fremstilling af α-phenyl-β-tetrahydofuryl-2-propionitriler eller syreadditionssalte heraf. | |
| DK106911C (da) | Fremgangsmåde til fremstilling af 2,3-dihydro-5-aryl-1H-1,4-benzodiazepinderivater eller syreadditionssalte deraf. |